Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 孙德生教授 (医学院) |
| 余卓文教授 (内科及药物治疗学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1016/j.jacc.2007.01.078 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/329WOS source URL
其它资讯
摘要Tissue Doppler imaging (TDI) is evolving as a useful echocardiographic tool for quantitative assessment of left ventricular (LV) systolic and diastolic function. Recent studies have explored the prognostic role of TDI-derived parameters in major cardiac diseases, such as heart failure, acute myocardial infarction, and hypertension. In these conditions, myocardial mitral annular or basal segmental (Sm) systolic and early diastolic (Ea or Em) velocities have been shown to predict mortality or cardiovascular events. In particular, those with reduced Sm or Em values of < 3 cm/s have a very poor prognosis. In heart failure and after myocardial infarction, noninvasive assessment of LV diastolic pressure by transmitral to mitral annular early diastolic velocity ratio (E/Ea or E/Em) is a strong prognosticator, especially when E/Ea is >= 15. In addition, systolic intraventricular dyssynchrony measured by segmental analysis of myocardial velocities is another independent predictor of adverse clinical outcome in heart failure subjects, even when the QRS duration is normal. In heart failure patients who received cardiac resynchronization therapy, the presence of systolic dyssynchrony at baseline is associated with favorable LV remodeling, which in turn predicts a favorable long-term clinical outcome. Finally, TDI and derived deformation parameters improve prognostic assessment during dobutamine stress echocardiography. A high mean Sm value in the basal segments of patients with suspected coronary artery disease is associated with lower mortality rate or myocardial infarction and is superior to the wall motion score. (J Am Coll Cardiol 2007;49:1903-14) (C) 2007 by the American College of Cardiology Foundation
着者Yu CM, Sanderson JE, Marwick TH, Oh JK
期刊名称JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
出版年份2007
月份5
日期15
卷号49
期次19
出版社ELSEVIER SCIENCE INC
页次1903 - 1914
国际标準期刊号0735-1097
电子国际标準期刊号1558-3597
语言英式英语
Web of Science 学科类别Cardiac & Cardiovascular Systems; CARDIAC & CARDIOVASCULAR SYSTEMS; Cardiovascular System & Cardiology
