Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 孙德生教授 (医学院) |
| 续平博士 (内科及药物治疗学系) |
| 胡锦生教授 |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1016/S0167-5273(97)00211-8 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/19WOS source URL
其它资讯
摘要The increasing prevalence of traditional atherosclerotic risk factors have been documented in Asia but the real impact on prevalence of coronary heart disease (CHD) remains unclear. Smoking, hypertension, hypercholesterolaemia, diabetes mellitus and obesity are present in only 508 of CHD. In community studies of Chinese in Hong Kong and southern mainland-China aging, smoking and hypercholesterolaemia were found to have a less impact on endothelial function in the Chinese compared with Caucasians in London and Sydney. As endothelial dysfunction is an early event in atherogenesis, there will be a strong need to search for newer risk factors for CHD in Asia, which may become more important in many Asian countries now in the process of modernization. Recently, heterozygous hyperhomocysteinaemia (with or without folate deficiency) was found to be an independent risk factor for arterial endothelial dysfunction, and hyperhomocysteinaemia in association with smoking was a significant risk factor for premature coronary heart disease in Hong Kong Chinese. Other newer factors which have emerged include folate deficiency, low HDL-cholesterol, insulin resistance, abdominal obesity, Methylene-tetrahydrofolate Reductase and Angiotensin Converting Enzyme gene polymorphism. (C) http://aims.cuhk.edu.hk/converis/portal/Publication/1997 Elsevier Science Ireland Ltd.
着者Woo KS, Chook P, Young RP, Sanderson JE
会议名称Asian Pacific Cardiovascular Update http://aims.cuhk.edu.hk/converis/portal/Publication/1997 Symposium on the 21st Century Approach
会议开始日05.06.http://aims.cuhk.edu.hk/converis/portal/Publication/1997
会议完结日06.06.http://aims.cuhk.edu.hk/converis/portal/Publication/1997
会议地点HONG KONG
期刊名称International Journal of Cardiology
出版年份http://aims.cuhk.edu.hk/converis/portal/Publication/1997
月份12
日期1
卷号62
出版社ELSEVIER SCI IRELAND LTD
页次S39 - S42
国际标準期刊号0167-5273
电子国际标準期刊号1874-1754
语言英式英语
关键词Asia; coronary heart disease; risk factors
Web of Science 学科类别Cardiac & Cardiovascular Systems; CARDIAC & CARDIOVASCULAR SYSTEMS; Cardiovascular System & Cardiology
