Publication in policy or professional journal
香港中文大学研究人员 ( 现职)
| 孙德生教授 (医学院) |
| 沈祖尧教授 (内科及药物治疗学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1136/hrt.76.4.305 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/61WOS source URL
其它资讯
摘要Hyperhomocysteinaemia and bacter pylori infection have been implicated in the pathogenesis of coronary artery disease. These two risk factors, though they seem unrelated, could be linked by a deficiency of vitamins and folate caused by chronic gastritis in H pylori infection. This nutritional defect could lead to failure of methylation by 5-methyl-tetrahydrofolic acid and thus exacerbate the accumulation of homocysteine in susceptible patients. Homocysteine is toxic to endothelial cells and results in coronary artery disease.
着者Sung JJY, Sanderson JE
期刊名称Heart
出版年份1996
月份10
日期1
卷号76
期次4
出版社BRITISH MED JOURNAL PUBL GROUP
国际标準期刊号1355-6037
电子国际标準期刊号1468-201X
语言英式英语
关键词coronary heart disease; Helicobacter pylori; hyperhomocysteinaemia
Web of Science 学科类别Cardiac & Cardiovascular Systems; CARDIAC & CARDIOVASCULAR SYSTEMS; Cardiovascular System & Cardiology
