Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 陈德威教授 (麻醉及深切治疗学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1093/bja/aew179 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/3WOS source URL
Scopushttp://aims.cuhk.edu.hk/converis/portal/Publication/3Scopus source URL
其它资讯
摘要Background Overt stroke after non-cardiac surgery has a substantial impact on the duration and quality of life. Covert stroke in the non-surgical setting is much more common than overt stroke and is associated with an increased risk of cognitive decline and dementia. Little is known about covert stroke after non-cardiac, non-carotid artery surgery. Methods We undertook a prospective, international cohort study to determine the incidence of covert stroke after non-cardiac, non-carotid artery surgery. Eligible patients were ≥65 yr of age and were admitted to hospital for at least three nights after non-cardiac, non-carotid artery surgery. Patients underwent a brain magnetic resonance study between postoperative days http://aims.cuhk.edu.hk/converis/portal/Publication/3 and 10. The main outcome was the incidence of perioperative covert stroke. Results We enrolled a total of 100 patients from six centres in four countries. The incidence of perioperative covert stroke was 10.0% (10/100 patients, 95% confidence interval 5.5-17.4%). Five of the six centres that enrolled patients reported an incident covert stroke, and covert stroke was found in patients undergoing major general (http://aims.cuhk.edu.hk/converis/portal/Publication/3/27), major orthopaedic (http://aims.cuhk.edu.hk/converis/portal/Publication/3/41), major urological or gynaecological (http://aims.cuhk.edu.hk/converis/portal/Publication/3/22), and low-risk surgery (1/12). Conclusions This international multicentre study suggests that 1 in 10 patients ≥65 yr of age experiences a perioperative covert stroke. A larger study is required to determine the impact of perioperative covert stroke on patient-important outcomes. Clinical trial registration NCT01http://aims.cuhk.edu.hk/converis/portal/Publication/3695http://aims.cuhk.edu.hk/converis/portal/Publication/37.
着者Mrkobrada M., Hill M.D., Chan M.T.V., Sigamani A., Cowan D., Kurz A., Sessler D.I., Jacka M., Graham M., Dasgupta M., Dunlop V., Emery D.J., Gulka I., Guyatt G., Heels-Ansdell D., Murkin J., Pettit S., Sahlas D.J., Sharma M., Sharma M., Srinathan S., St John P., Tsai S., Gelb A.W., O'Donnell M., Siu D., Chiu P.W.Y., Sharath V., George A., Devereaux P.J.
期刊名称British Journal of Anaesthesia
出版年份2016
月份8
日期1
卷号117
期次2
出版社Oxford University Press
出版地United Kingdom
页次191 - 197
国际标準期刊号0007-0912
电子国际标準期刊号1471-6771
语言英式英语
关键词magnetic resonance imaging, perioperative period, stroke
