Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 陈德威教授 (麻醉及深切治疗学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1016/j.bpa.2011.06.005 |
引用次数
Scopushttp://aims.cuhk.edu.hk/converis/portal/Publication/4Scopus source URL
其它资讯
摘要Inflammation is an adaptive response to surgery. When the pro-inflammatory responses are unregulated and become over reactive, systemic inflammatory response syndrome may occur. Postoperative systemic inflammation is more common than is generally acknowledged and is observed in about 10-15% of elderly patients undergoing major surgery. Although the vast majority of systemic inflammation is related to infections, other important predisposing risk factors, such as extent of trauma and haemorrhage, should not be overlooked. Increased awareness, modification of risk factors and early recognition are the key elements in the management of systemic inflammation. Prompt resuscitation aiming to correct hypotension, hypovolaemia and tissue hypoxia may improve outcome. Future large prospective observational studies are needed to define the incidence, risk factors and impact of systemic inflammatory syndrome in the elderly surgical patients. A better understanding of the molecular events during the systemic inflammatory response syndrome is required for future development of specific immunotherapy. ? 2011 Elsevier Ltd. All rights reserved.
着者Koo E.G.Y., Lai L.M.L., Choi G.Y.S., Chan M.T.V.
期刊名称Best Practice and Research: Clinical Anaesthesiology
出版年份2011
月份9
日期1
卷号25
期次3
出版社Bailliere Tindall
出版地United Kingdom
页次http://aims.cuhk.edu.hk/converis/portal/Publication/413 - http://aims.cuhk.edu.hk/converis/portal/Publication/425
国际标準期刊号1521-6896
语言英式英语
关键词aged, immunotherapy, infection, inflammation, postoperative complications, sepsis, surgery, systemic inflammatory response syndrome
