Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 陈德威教授 (麻醉及深切治疗学系) |
| Professor Tony GIN (麻醉及深切治疗学系) |
| 周家明教授 (建筑学院) |
| 许树昌教授 (内科及药物治疗学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1378/chest.08-1998 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/18WOS source URL
Scopushttp://aims.cuhk.edu.hk/converis/portal/Publication/26Scopus source URL
其它资讯
摘要Background: As part of our influenza pandemic preparedness, we studied the dispersion distances of exhaled air and aerosolized droplets during application of a jet nebulizer to a human patient simulator (HPS) programmed at normal lung condition and different severities of lung injury. Methods: The experiments were conducted in a hospital isolation room with a pressure of - 5 Pa. Airflow was marked with intrapulmonary smoke. The jet nebulizer was driven by air at a constant flow rate of 6 L/min, with the mask reservoir filled with sterile water and attached to the HPS via a nebulizer mask. The exhaled leakage jet plume was revealed by a laser light sheet and images captured by high-definition video. Smoke concentration in the plume was estimated from the light scattered by smoke and droplet particles. Findings: The maximum dispersion distance of smoke particles through the nebulizer side vent was 0.45 in lateral to the HPS at normal lung condition (oxygen consumption, 200 mL/min; lung compliance, 70 mL/cm H2O), but it increased to 0.54 m in mild lung injury (oxygen consumption, 300 mL/min; lung compliance, 35 mL/cm H2O), and beyond 0.8 m in severe lung injury (oxygen consumption, 500 mL/min; lung compliance, 10 mL/cm H2O). More extensive leakage through the side vents of the nebulizer mask was noted with more severe lung injury. Interpretation: Health-care workers should take extra protective precaution within at least 0.8 m from patients with febrile respiratory illness of unknown etiology receiving treatment via a jet nebulizer even in an isolation room with negative pressure. Copyright ? 2009 American College of Chest Physicians.
着者Hui D.S., Chow B.K., Chu L.C.Y., Ng S.S., Hall S.D., Gin T., Chan M.T.V.
期刊名称Chest
出版年份2009
月份3
日期1
卷号135
期次3
出版社Elsevier Inc.
出版地United States
页次648 - 654
国际标準期刊号0012-3692
语言英式英语
关键词Dispersion, Exhaled air, Influenza, Jet nebulizer, Severe acute respiratory syndrome
