A COMPARISON BETWEEN KETOROLAC AND DICLOFENAC IN LAPAROSCOPIC STERILIZATION
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香港中文大学研究人员 ( 现职)

Professor Tony GIN (麻醉及深切治疗学系)

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Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/9WOS source URL

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摘要We compared ketorolac and diclofenac for the prevention and treatment of post-operative pain in patients undergoing laparoscopic sterilization. Fifty ASA I or II women were allocated randomly to receive either diclofenac 75 mg or ketorolac 30 mg intramuscularly 30-http://aims.cuhk.edu.hk/converis/portal/Publication/90 min before general anaesthesia. Pain scores were assessed half-hourly in the recovery room and then at 2 h and 4 h in the ward. In the recovery room, pain was treated with a second dose of the study drug, followed by parenteral pethidine if necessary. Four patients in the diclofenac group and five patients in the ketorolac group requested no analgesics after surgery. Fifteen patients from each group had satisfactory analgesia after the second dose of study drug. Pain scores were similar between groups at all times. The median (range) initial pain score in the recovery room was 5 (0-http://aims.cuhk.edu.hk/converis/portal/Publication/9.5) in the diclofenac group and 5 (1-http://aims.cuhk.edu.hk/converis/portal/Publication/9) in the ketorolac group. Pain at the injection site was more common after diclofenac than ketorolac (12 vs. 3, P < 0.05). In conclusion, both intramuscular diclofenac and ketorolac were relatively ineffective in controlling the pain after laparoscopic sterilization. The drugs were equally well tolerated, but more patients complained of pain at the injection site after diclofenac.

着者CHUI PT, GIN T
期刊名称European Journal of Anaesthesiology
出版年份1http://aims.cuhk.edu.hk/converis/portal/Publication/9http://aims.cuhk.edu.hk/converis/portal/Publication/95
月份11
日期1
卷号12
期次6
出版社BLACKWELL SCIENCE LTD
页次5http://aims.cuhk.edu.hk/converis/portal/Publication/97 - 601
国际标準期刊号0265-0215
语言英式英语

关键词ANALGESICS, DICLOFENAC, KETOROLAC; PAIN, POSTOPERATIVE; SURGERY, LAPAROSCOPY, STERILIZATION
Web of Science 学科类别Anesthesiology; ANESTHESIOLOGY