Publication in refereed journal
香港中文大学研究人员 ( 现职)
| Professor Tony GIN (麻醉及深切治疗学系) |
| 郭志德教授 (麻醉及深切治疗学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1093/bja/72.2.151 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/39WOS source URL
其它资讯
摘要We have compared three methods of preventing hypotension during subarachnoid anaesthesia. We attempted to maintain systolic arterial pressure (SAP) greater than 75% of baseline by use of i.v. fluids (preloading with normal saline 16ml kg(-1) and, if necessary, three subsequent boluses of 2.5 ml kg(-1)), an infusion of metaraminol titrated as necessary between 0 and 5 mg h(-1) and an infusion of ephedrine titrated as necessary between 0 and 120 mg h(-1). SAP and mean arterial pressure (MAP) were measured by automated oscillotonometry, central venous pressure (CVP) by a manometer and cardiac index (Cl), stroke index (Sl) and heart rare (HR) by transthoracic electrical bioimpedance. Systemic vascular resistance index (SVRI) was derived. Fluids alone failed to maintain SAP in five of 10 patients. Although Cl and CVP were maintained SVRI decreased (25 (SD 15)%; P = 0.02). Metaraminol maintained SAP in all 12 patients. The main cardiovascular change was decreased HR (15 (8)%; P = 0.0001). Ephedrine failed to maintain SAP in two of 12 patients and was accompanied by several cardiovascular changes: HR (21 (12)%; P = 0.001) increased and Sl(16 (10)%; P = 0.0001), CVP (3.8 (1.5) cm H2O; P = 0.0001) and SVRI (24 (6)%; P = 0.0001) decreased. Treatment failures resulted from failures to maintain SVRI in the fluid group and CVP and SVRI in the ephedrine group.
着者CRITCHLEY LAH, SHORT TG, GIN T
期刊名称British Journal of Anaesthesia
出版年份1994
月份2
日期1
卷号72
期次2
出版社PROF SCI PUBL
页次151 - 155
国际标準期刊号0007-0912
电子国际标準期刊号1471-6771
语言英式英语
关键词ANESTHETIC TECHNIQUES, SUBARACHNOID; COMPLICATIONS, HYPOTENSION
Web of Science 学科类别Anesthesiology; ANESTHESIOLOGY
