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Advances in the clinical laboratory assessment of urinary sediment (2004)_香港中文大学化學病理學系 (CPY)研究成果

香港中文大学 辅仁网/2017-06-20

Advances in the clinical laboratory assessment of urinary sediment
Publication in refereed journal


香港中文大学研究人员 ( 现职)
司徒卓俊教授 (内科及药物治疗学系)
陈颖欣博士 (化学病理学系)


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Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/12WOS source URL

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摘要Urinalysis has been used extensively in clinical practice to aid in the diagnosis of various renal and urologic diseases. The innovation of urinalysis is marching on right along with the rapid developments in biotechnology and astride from the solo urine cytology to sophisticated studies of individual component in the urinary sediment. In this review article, we focus on the use of flow cytometry and other technical advances in the examination of urinary sediment, the detection of urologic malignancies by the presence of microsatellite alteration in the urinary sediment, as well as the quantification of cytokine messenger RNA (mRNA) expression in urinary sediment by reverse transcription and real-time quantitative polymerase chain reaction (RT-QPCR). Notably, the study of cytokine mRNA expression in urinary sediment by RT-QPCR has recently been reported to provide important diagnostic information in kidney allograft recipients and patients with lupus nephritis. This simple and non-invasive method requires further study to determine its role in risk stratification and monitoring of therapeutic response in patients with other kidney diseases. (C) 2003 Elsevier B.V. All rights reserved.

着者Chan RWY, Szeto CC
期刊名称Clinica Chimica Acta
出版年份2004
月份2
日期1
卷号340
期次1-2
出版社ELSEVIER SCIENCE BV
页次67 - 78
国际标準期刊号0009-8981
电子国际标準期刊号1873-3492
语言英式英语

关键词flow cytometry; kidney; urinalysis; urology
Web of Science 学科类别Medical Laboratory Technology; MEDICAL LABORATORY TECHNOLOGY

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