Dr. WANG Lidai (王立代 博士) BS & Ms (Tsinghua University), PhD (University of Toronto)



Associate Professor


Contact Information Office: Y6619AC1
Phone: 34426157
Email: lidawang@cityu.edu.hk
Web: Google scholar profile

Research Interests Photoacoustic imaging
Computational optics
Wavefront engineering
Biomedical instrumentation



Lidai Wang received the Bachelor and Master degrees from the Tsinghua University, Beijing, and received the Ph.D. degree from the University of Toronto, Canada. After working as a postdoctoral research fellow in the Prof Lihong Wang's group, he joined the City University of Hong Kong in 2015. His research focuses on biophotonics, biomedical imaging, wavefront engineering, instrumentation and their biomedical applications. He has invented single-cell flowoxigraphy, ultrasonically encoded photoacoustic flowgraphy and nonlinear photoacoustic guided wavefront shaping. He has published more than 60 articles in peer-reviewed journals and has received four best paper awards from international conferences.


Research Grants Multiscale photoacoustic molecular imaging for early diagnos, National Natural Science Foundation of China, Aug 2019 - Now, Co-PI.
Development of Optical-resolution Photoacoustic Microscopy with Compensation of Absorption Saturation, General Research Fund , Jan 2019 - Dec 2021, PI.
Development of a Magnetic Driven Microrobotic Control System for In-vivo Transportation of Cell-cultured Microrobots, Innovation and Technology Fund , Innovation and Technology Commission of Hong Kong, Aug 2018 - Now, Co-PI.
Development and mechanism study of chitosan/graphene oxide hemostatic sponge, Shenzhen Foundamental Research Fund, Jan 2018 - Dec 2020, PI.
Quantitative Photoacoustic Imaging of Blood Oxygen Saturation in Deep Tissue, General Research Fund , Research Grants Council of Hong Kong, Jul 2017 - Now, PI.
Large-scale single-cell photoacoustic microscopy of the brain in action, Early Career Scheme, Research Grants Council of Hong Kong, Jan 2017 - Dec 2019, Lidai Wang (PI).
Multiscale functional and molecular photoacoustic imaging and guidance technology for liver cancer surgery, National Natural Science Foundation of China, Jan 2017 - Dec 2021, Lidai Wang (Co-PI).
Development of micro/nano robotic technology for multi-dimensional diagnosis of cancer cells, Shenzhen Basic Research Fund, Jan 2016 - Dec 2018, Lidai Wang (Co-PI).
Development of photoacoustic tomography for deep brain functional imaging and early cancer detection, City University of Hong Kong Start-Up Fund, Sep 2015 - Aug 2017, Lidai Wang (PI).



Patents Lidai Wang, Yizhi Liang, System and Method for Providing Multi-Wavelength Laser, US Patent No. 15/493,283, 21 Apr 2017. (Licensed).
Lihong V. Wang, Lidai Wang, Chi Zhang, Puxiang Lai, and Jian Wei Tay, Systems and methods of grueneisen-relaxation photoacoustic microscopy and wavefront shaping, US Patent No. US2, 2015.
Lihong V. Wang, Konstantin Maslov, Lidai Wang, Single-cell label-free photoacoustic flowoxigraphy in vivo, US Patent No. US2 , 2014.



Publications Show All Publications Show Prominent Publications
Journal CHEN, Jiangbo. , ZHANG, Yachao. , HE, Linyun. , LIANG, Yizhi. & WANG, Lidai. (Jun 2020). Wide-field polygon-scanning photoacoustic microscopy of oxygen saturation at 1-MHz A-line rate. Photoacoustics. 100195.
LIANG, Yizhi. , LIU, Huan. , LI, Qiang. , JIN, Long. , GUAN, Bai-ou. & WANG, Lidai. (2020). Acoustic-spectrum-compensated photoacoustic microscopy. Optics Letters. 45/7. 1850.
LU, YU. , CHEN, FENG. & WANG, LIDAI. (2020). An invertible wavefront switching system with a high extinction ratio. Optics & Laser Technology. 131. 106466.
Wei, Tanyong. , Liu, Jiang. , Li, Dongfang. , Chen, Shuxun. , Zhang, Yachao. , Li, Junyang. , Fan, Lei. , Guan, Zhangyan. , Lo, Chung‐Mau. , Wang, Lidai. , Man, Kwan. & Sun, Dong. (2020). Development of Magnet‐Driven and Image‐Guided Degradable Microrobots for the Precise Delivery of Engineered Stem Cells for Cancer Therapy. Small. 16/41. 1doi:10.1002/smll.201906908
LI, Mingsheng. , CHEN, Jiangbo. & WANG, Lidai. (2020). High acoustic numerical aperture photoacoustic microscopy with improved sensitivity. Optics Letters. 45/3. 628.
ZHOU, Yingying. , LIANG, Siyi. , LI, Mingsheng. , LIU, Chengbo. , LAI, Puxiang. & WANG, Lidai. (2020). Optical‐resolution photoacoustic microscopy with ultrafast dual‐wavelength excitation. Journal of Biophotonics. e201960229.
LI, Shengliang. , Deng, Q. , ZHANG, Y. , LI, X. , WEN, G. , CUI, X. , WAN, Y. , HUANG, Y. , CHEN, J. , LIU, J. , WANG, L. & LEE, C. (2020). Rational Design of Conjugated Small Molecules for Superior Photothermal Theranostics in the NIR‐II Biowindow. Advanced Materials. 32/33. 2001146.
LU, YU. , WONG, Terence. TW. , CHEN, FENG. & WANG, LIDAI. (May 2019). Compressed Ultrafast Spectral-Temporal Photography. Physical Review Letters. 122. 193904.
LIANG, YIZHI. , LIU, JIN-WEI. , JIN, LONG. , GUAN, BAIOU. & WANG, LIDAI. (2018). Fast-scanning photoacoustic microscopy with a side-looking fiber optic ultrasound sensor. Biomedical Optics Express. 9/11. 5809- 5816.
BAI, XUE. , LIANG, YIZHI. , SUN, HUOJIAO. , JIN, LONG. , MA, JUN. , GUAN, BAIOU. & WANG, LIDAI. (24 Jul 2017). Sensitivity characteristics of broadband fiber-laser-based ultrasound sensors for photoacoustic microscopy. Optics Express. 25/15. 17616- 17626.
Liang, Yizhi. , Jin, Long. , Guan, Bai-ou. & Wang, Lidai. (2017). 2 MHz multi-wavelength pulsed laser for functional photoacoustic microscopy. Optics Letters. 42/7.
Liang, Yizhi. , Jin, Long. , Wang, Lidai. , Bai, Xue. , Cheng, Linghao. & Guan, Bai-Ou. (2017). Fiber-Laser-Based Ultrasound Sensor for Photoacoustic Imaging. Scientific reports. 7.
Lin, Li. , Hai, Pengfei. , Xu, Song. , Shi, Junhui. , Li, Lei. , Yao, Junjie. , Wang, Lidai. , Zou, Jun. & Wang, Lihong. V. (2017). Handheld optical-resolution photoacoustic microscopy. Journal of Biomedical Optics. 22/4. doi:10.1117/1.JBO.22.4.041002
Li, Lei. , Zhu, Liren. , Ma, Cheng. , Lin, Li. , Yao, Junjie. , Wang, Lidai. , Maslov, Konstantin. , Zhang, Ruiying. , Chen, Wanyi. , Shi, Junhui. & Wang, Lihong. V. (2017). Single-impulse panoramic photoacoustic computed tomography of small-animal whole-body dynamics at high spatiotemporal resolution. Nature Biomedical Engineering. 1/5. doi:10.1038/s41551-017-0071
Lin, Li. , Yao, Junjie. , Zhang, Ruiying. , Chen, Chun-cheng. , Huang, Chih-Hsien. , Li, Yang. , Wang, Lidai. , Chapman, William. , Zou, Jun. & Wang, Lihong. V. (2016). High‐speed photoacoustic microscopy of mouse cortical microhemodynamics. Journal of Biophotonics. doi:10.1002/jbio.201600236
He, Yun. , Wang, Lidai. , Junhui, Shi. & et al(2016). In vivo label-free photoacoustic flow cytography and on-the-spot laser killing of single circulating melanoma cells. Scientific Reports. 6. doi:10.1038/srep39616
Hsu, Hsun-Chia. , Wang, Lidai. & Wang, Lihong. V. (2016). In vivo photoacoustic microscopy of human cuticle microvasculature with single-cell resolution. Journal of biomedical optics. 21/5. doi:10.1117/1.JBO.21.5.056004
Yao, Junjie. , Kaberniuk, Andrii. A. , Li, Lei. , Shcherbakova, Daria. M. , Zhang, Ruiying. , Wang, Lidai. , Li, Guo. , Verkhusha, Vladislav. V. & Wang, Lihong. V. (2016). Multiscale photoacoustic tomography using reversibly switchable bacterial phytochrome as a near-infrared photochromic probe. Nature methods. 13. doi:10.1038/nmeth.3656
Shi, Junhui. , Wang, Lidai. , Noordam, Cedric. & Wang, Lihong. (2015). Bessel-beam Grueneisen relaxation photoacoustic microscopy with extended depth of field. Journal of Biomedical Optics. 20/11. doi:10.1117/1.JBO.20.11.116002
Shi, Junhui. , Wang, Lidai. , Noordam, Cedric. & Wang, Lihong. (2015). Bessel-beam Grueneisen relaxation photoacoustic microscopy with extended depth of field. Journal of Biomedical Optics. 20/11. doi:10.1117/1.JBO.20.11.116002
Yao, Junjie. , Wang, Lidai. & et al(2015). High-speed label-free functional photoacoustic microscopy of mouse brain in action. Nature methods. 12/5.
Lai, Puxiang. , Wang, Lidai. , Tay, Jian Wei. & Wang, Lihong. (2015). Photoacoustically guided wavefront shaping for enhanced optical focusing in scattering media. Nature photonics. 9/2.
Wang, Lidai. , Li, Guo. , Xia, Jun. & Wang, Lihong. (2015). Ultrasonic-heating-encoded photoacoustic tomography with virtually augmented detection view. Optica. 2/4.
Yao, Junjie. & et al(2014). Calibration-free structured-illumination photoacoustic flowgraphy of transverse flow in scattering media. Journal of biomedical optics. 19/4.
Li, Lei. & et al(2014). Fully motorized optical-resolution photoacoustic microscopy. Optics letters. 39/7.
Wang, Lidai. , Zhang, Chi. & Wang, Lihong. V. (2014). Grueneisen relaxation photoacoustic microscopy. Physical review letters. 113/17.
zhang, ruiying. , wang, lidai. & et al(2014). In vivo optically encoded photoacoustic flowgraphy. Optics letters. 39/13. doi:10.1364/OL.39.003814
Danielli, Amos. , Maslov, Konstantin. & et at(2014). Label-free photoacoustic nanoscopy. Journal of biomedical optics. 19/8. doi:10.1117/1.JBO.19.8.086006
Yao, Junjie. , Zhang, Chi. , Wang, Lidai. , Zhang, Chi. & Wang, Lihong. V. (2014). Photoimprint photoacoustic microscopy for three-dimensional label-free subdiffraction imaging. Physical review letters. 112/1. doi:10.1103/PhysRevLett.112.014302
Xia, Jun. & et al(2013). Calibration-free quantification of absolute oxygen saturation based on the dynamics of photoacoustic signals. Optics letters. 38/15.
Zhang, Yu. , Wang, Yu. , Wang, Lidai. & et al(2013). Labeling Human Mesenchymal Stem Cells with Gold Nanocages forin vitroandin vivoTracking by Two-Photon Microscopy and Photoacoustic Microscopy. Theranostics. 3/8.
Gao, Liang. , Wang, Lidai. & et al(2013). Photothermal bleaching in time‐lapse photoacoustic microscopy. Journal of biophotonics. 6/6-7.
Wang, Lidai. , Maslov, Konstantin. & Wang, Lihong. V. (2013). Single-cell label-free photoacoustic flowoxigraphy in vivo. Proceedings of the National Academy of Sciences. 110/15. doi:10.1073/pnas.1215578110
Gao, Liang. , Wang, Lidai. & et al(2013). Single-cell photoacoustic thermometry. Journal of biomedical optics. 18/2.
Wang, Lidai. , Xia, Jun. , Yao, Junjie. , Maslov, Konstantin. & Wang, Lihong. (2013). Ultrasonically encoded photoacoustic flowgraphy in biological tissue. Physical review letters. 111/20. doi:10.1103/PhysRevLett.111.204301
Wang, Lidai. , Yao, Junjie. & et al(2013). Ultrasound-heated photoacoustic flowmetry. Journal of biomedical optics. 18/11.
Rowland, K. & et al(2013). Up-regulation of hypoxia-inducible factor 1 alpha and hemodynamic responses following massive small bowel resection. Journal of pediatric surgery. 48/6.
Xia, Jun. , Li, Guo. , Wang, Lidai. & et al(2013). Wide-field two-dimensional multifocal optical-resolution photoacoustic-computed microscopy. Optics letters. 38/24.
Wang, Lidai. & et al(2012). Video-rate functional photoacoustic microscopy at depths. Journal of biomedical optics. 17/10.
Wang, Lidai. , Maslov, Konstantin. , Yao, Junjie. & et al(2011). Fast voice-coil scanning optical-resolution photoacoustic microscopy. Optics Letters. 36/2.




External Services
Professional Activity 2020 - Now, Editorial Board, Photoacoustics Journal.
2016 - Now, Topical editor of Applied Optics.




Service in CityU
Teaching Service Jan 2017 - Now, Biomedical photonics.
Sep 2016 - Now, Instrumentation and testing technologies.
Jan 2016 - Now, Biomedical instrumentation.
Jan 2016 - Now, Engineering Graphics.




Group members Postdoctoral fellows
LIU, Chao City University of Hong Kong
ZHANG, Yachao City University of Hong Kong
PhD students
LU, Yu Xi'an Jiaotong University
CHEN, Jiangbo Harbin Institute of Technology
LIANG, Siyi Sichuan University
ZHU, Jingyi Zhejing University
YAO, Kuanming Zhejiang University
WANG, Yue Dalian University of Technology
QU, Zheng Tianjin University
Visiting students
ZHOU, Yingying Hong Kong Polytechnic University

Former members
LIANG, Yizhi
WEN, Guohua
LIN, Xiangwei
Han, Qi
LI, Mingsheng
He, Linyun
QI, Shuo



Last update date : 27 Oct 2020