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研究员
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博士
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(+86)
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yaokang@isa.ac.cn
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研究员
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湖南省长沙市芙蓉区远大二路644号
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研究员，博士生导师。2002年7月毕业于华中农业大学畜牧兽医专业，获农学学士学位；2005年7月毕业于华中农业大学动物科技学院，获得猪遗传育种与营养调控专业硕士学位；2009年3月毕业于中国科学院亚热带农业生态研究所，获得动物营养与生态专业博士学位。2009年5月至2014年3月在Department of Animal Science, Texas A&M University进行科研工作。目前主要从事单胃动物营养和氨基酸营养的研究。
从事单胃动物(猪)的营养研究以来，主要以进一步提高营养成分利用效率，促进蛋白质合成和沉积为研究方向，并围绕氨基酸及氨基酸代谢中间产物对蛋白质合成及合成信号通路即mTOR信号通路中各蛋白质翻译起始因子的调节作用开展了各项工作,先后参加国家自然科学基金项目3项、国家973课题2项，先后主持国家自然科学基金青年基金项目、湖南省自然科学基金重点项目各1项，973项目专项负责人，发表学术论文20余篇，SCI 收录16篇，文章收录发表后截止2014年3月他引次数达334次，参与编写专著1部，作为主要完成人获湖南省自然科学一等奖1项。

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发表英文论文目录：
1. Kang Yao, Yulong Yin, Guoyao Wu, Dun Deng, Zhiqiang Liu, Tijun Li, Ruilin Huang, Wuyin Chu, Bie Tan and Wence Wang. Dietary Arginine Supplementation Increases mTOR Signaling Activity in Skeletal Muscle of Neonatal Pigs. Journal of Nutrition. 2008：867-872
2. Kang Yao, Dun Deng, Wuying Chu，Tiejun Li , Ruiling Huang , Yulong Yin Zhiqiang Liu , Jianshe Zhang , and Guoyao Wu. Impaired translation initiation activation and reduced protein synthesis in weaned piglets fed a low-protein diet. Journal of Nutritional Biochemistry. (Co-author made equal contributions to the study) 2009 20 (7)：544-552
3. Kang Yao, Yu-Long Yin, Guoyao Wu, Dun Deng, Zhiqiang Liu, Tijun Li, Ruilin Huang, Wuyin Chu, Bie Tan and Wence Wang. Dietary L-arginine supplementation enhances intestinal development and expression of vascular endothelial growth factor in weanling piglets. British journal of nutrition. 105(5):703-9
4. Kang Yao , Yulong Yin Zhiqiang Liu , Jianshe Zhang , and Guoyao Wu. Tryptophan metabolism and its implications for nutrition. Frontiers in Bioscience. S3, 286-297
5. Kang Yao, Yulong Yin, Xilong Li, Pengbin Xi, Junjun Wang, Jian Lei, Yongqing Hou, Guoyao Wu. Alpha-ketoglutarate inhibits glutamine degradation and enhances protein synthesis in intestinal porcine epithelial cells. Amino Acids. DOI 10.1007/s00726-011-1060-6
6. Kang Yao，Li Wu, Wence Wang, Ting Zhou, Jie Yin, Tiejun Li, Lin Yang, Liuqin He, Xiaojian Yang, Hongfu Zhang, Qi Wang, Ruilin Huang, Yulong Yin. Effects of Dietary Arginine and Glutamine on Alleviating the Impairment Induced by Deoxynivalenol Stress and Immune Relevant Cytokines in Growing Pigs. (Co-author made equal contributions to the study) PLoS ONE. 2013 8(7): e69502. doi:10.1371/journal.pone.**
7. Kang Yao, Chenxing Fu, Sudath Dahanayaka, Jian Lei, Wei Lu, Guoyao Wu and YulongYin. Dietary alpha-ketoglutarate supplementation may increases muscle gain through mTOR signaling pathway in diet-induced obese rat. JFAE 2013 11 (3&4) - 2013
8. Zhengfeng Fang, Kang Yao, Xiaoling Zhang, Shengjun Zhao, Zhihong Sun, Gang Tian, Bing Yu, Yan Lin, Biquan Zhu, Gang Jia, Keying Zhang, Daiwen Chen, De Wu. Nutrition and health relevant regulation of intestinal sulfur amino acid metabolism. Amino Acids. (2010) 39:633–640.
9. Yulong Yin, Kang Yao, Zhaojin Liu, Min Gong, Zheng Ruan, Dun Deng, Bie Tan, Zhiqiang Liu, Guoyao Wu. Supplementing L-leucine to a low-protein diet increases tissue protein synthesis in weanling pigs. Amino Acids. (2010) 39:1477–1486
10. Yongqing Hou, Kang Yao, Lei Wang1, Binying Ding, Dabo Fu, Yulan Liu, Huiling Zhu, Jian Liu, Yongtang Li, Ping Kang, Yulong Yin and Guoyao Wu. Effects of α-ketoglutarate on energy status in the intestinal mucosa of weaned piglets chronically challenged with lipopolysaccharide. Brtish Journal Nutrition. (2011), 106, 357–363
11. Pengbin Xi, Zongyong Jiang, Zhaolai Dai, Xilong Li, Kang Yao, Chuntian Zheng,Yingcai Lin, Junjun Wang, Guoyao Wu. Regulation of protein turnover by L-glutamine in porcine intestinal epithelial cells. Journal of Nutritional Biochemistry. 2012,23(8):1012-7
12.Jian Lei, Dingyuan Feng, Yongliang Zhang, Sudath Dahanayaka, Xilong Li, Kang Yao, Junjun Wang, Zhenlong Wu, Zhaolai Dai, Guoyao Wu. Regulation of leucine catabolism by metabolic fuels in mammary epithelial cells. Amino Acids. (2012) 04/2012; 43(5):2179-89.
13.Jian Lei, Dingyuan Feng, Yongliang Zhang, Sudath Dahanayaka, Xilong Li, Kang Yao, Junjun Wang, Zhenlong Wu, Zhaolai Dai, Guoyao Wu. Hormonal regulation of leucine catabolism in mammary epithelial cells.Amino Acids. (2012) DOI 10.1007/s00726-012-1332-9
14.Carmen D. Tekwe, Jian Lei, Kang Yao, Reza Rezaei, Xilong Li, Sudath Dahanayaka, Raymond J. Carroll, Cynthia J. Meininger, Fuller W. Bazer, Guoyao Wu. Oral administration of interferon tau enhances oxidation of energy substrates and reduces adiposity in Zucker diabetic fatty rats. BioFactors. (2013) DOI 10.1002/biof.1113.
15.Bie Tan, Yulong Yin, Zhiqiang Liu, Wenjie Tang, Haijun Xu,Xiangfeng Kong, Xinguo Li, Kang Yao, Wanting Gu, Stephen B Smith, Guoyao Wu. Dietary L-arginine supplementation differentially regulates expression of lipid-metabolic genes in porcine adipose tissue and skeletal muscle. The Journal of nutritional biochemistry (2011); 22(5):441-5.
16.Bie Tan, Xinguo G Li, Xiangfeng Kong, Ruilin Huang, Zheng Ruan, Kang Yao, Zeyuan Deng, Mingyong Xie, Izuru Shinzato, Yulong Yin,Guoyao Wu. Dietary L-arginine supplementation enhances the immune status in early-weaned piglets. Amino Acids 09/2008; 37(2):323-31.
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主持项目：
2010.1-2012.12 国家自然科学基金青年基金项目“a-酮戊二酸对谷氨酰胺在肠道第一代谢率的影响作用及机理的研究”（**），为项目负责人。
2012.1-2014.12 湖南省自然科学基金重点项目“呕吐毒素解毒酶构建及其对饲料营养物质吸收的影响机制”(12JJ2020)，为项目负责人。
2013.1-2017. 12国家973项目“氮营养素消化代谢网络的整合机制与营养调控”，子课题负责人。