职 务：
职 称：国家一级研究员学 历：博士
电 话：(86)-**通迅地址：湖南省长沙市芙蓉区远大二路644号
传 真：(86)-**邮政编码：410125
电子邮件：yinyulong@isa.ac.cn
- 简历一级研究员，博士生和博士后导师。中国工程院院士，中科院“百人计划人选”。曾于1985-1987，1994-1999分别在德国国家农科院动物营养所，英国女皇大学，加拿大Guelph大学学习和工作，获英国女皇大学哲学博士学位。农业部动物营养实验室群名誉理事长，动物营养学国家重点实验室、生物饲料安全与污染防控国家工程实验室学术委员会委员。中国畜牧兽医学会动物营养分会副理事长，先后获全国五一劳动奖章、九三学社全国优秀社员、中科院创新文化先进奖和优秀共产党员等殊荣。长期从事“猪氨基酸营养代谢与调控” 研究，带领团队在影响因子超过3.0和一区SCI期刊发表论文100多篇，H指数高达41,进入Plnat & Animal Science,Biology & Biochemistry 和Agricultural Sciences世界前1%科学家行列，2014年获美国汤森路透中国引文桂冠奖（中国农业界别唯一获得者）。主编中英文著作4部，获国家发明专利24项，其成果先后获国家科技进步奖4项。
- 承担科研项目 1.基因工程生产富乳铁蛋白素的功能饲料及食品，国家863项目
2.动物重要氨基酸吸收转运的分子机制与营养调控机理，中国科学院知识创新重 要方向项目
3.小型猪蛋白质氨基酸营养代谢机理研究，国家自然科学基金面上项目
4.仔猪肠道健康及功能性饲料研究与应用，
5.家养动物营养组学研究体系的建立与应用，企业和自选项目
6.功能性氨基酸和碳水化合物的研发，企业和自选项目
- 代表论著1 Fu J, Wenzel SC, Perlovan O, Wang JP, Gross F, Tang ZR, Yin YL, Stewart AF, Muller R and Zhang YM, Efficient transfer of two large secondary metabolite pathway gene clusters into heterologous hosts by transposition. Nucleic Acids Research 36: 113-114 (2008).
2 Dekaney CM, Wu GY, Yin YL and Jaeger LA, Regulation of ornithine aminotransferase gene expression and activity by all-transretinoic acid in Caco-2 intestinal epithelial cells. The Journal of Nutritional Biochemistry 19 : 674-681 (2008).
3 Yao K, Yin YL, Chu WY, Liu ZQ, Dun D, Li TJ, Huang RL, Zhang JS, Tan Bie, Wang WC and Wu GY, Dietary Arginine Supplementation Increases mTOR Signaling Activity in Skeletal Muscle of Neonatal Pigs. J Nutr 138: 867-872 (2008).
4 Wang JJ, Chen LX, Li P, Li XL, Zhou HJ, Wang FL, Li DF, Yin YL and Wu GY, Gene Expression is Altered in Piglet Small Intestine by Weaning and Dietary Glutamine Supplementation. J Nutr 138: 1025-1032 (2008).
5 Zeng XF, Feng L, Fan X, Yang WJ, Zhou B, Li PF, Yin YL, Wu GY and Wang JJ, Dietary arginine supplementation during early pregnancy enhances embryonic survival in rates.Journal of Nutrition 138:1421-1425 (2008).
6 Wang JJ, Chen LX, Li DF, Yin YL, Wang XQ, Li P, Dangott LJ, Hu WX and Wu GY, Intrauterine Growth Restriction Affects the Proteomes of the Small Intestine, Liver, and Skeletal Muscle in Newborn Pigs. The Journal of Nutrition 138: 60-66 (2008).
7 Liu YL, Huang JJ, Hou YQ, Zhu HL, Zhao SJ, Ding BY, Yin YL, Yi GF, Shi JX and Fan W, Dietary arginine supplementation alleviates intestinal mucosal disruption induced by Escherichia coli lipopolysaccharide in weaned pigs. British Journal of Nutrition 100:552-560 (2008).
8 Han J, Liu YL, Fan W, Chao J, Hou YQ, Yin YL, Zhu HL, Meng GQ and Che ZQ, Dietary L-arginine supplementation alleviates immunosuppression induced by cyclophosphamide in weaned pigs. Amino Acids 37:643-651 (2008).
9 Tan Bie, Yin YL, Liu ZQ, Li XG, Xu HJ, Kong XF, Huang RL, Tang WJ, Shinzato I, Smith SB and Wu GY, Dietary L-arginine supplementation increases muscle gain and reduces body fat mass in growing-finishing pigs. Amino Acids 37:169-175 (2009).
10 Kong X.F, Yin YL, He QH, Yin FG, Liu HJ, Li TJ, Huang RL, Geng MM, Ruan Z, Deng ZY, Xie MY and Wu G, Dietary supplementation with Chinese herbal powder enhances ileal digestibilities and serum concentrations of amino acids in young pigs. Amino Acids 37:573-582 (2008) .
11 Yin YL, Li TJ and Huang RL, Evaluating standardized ileal digestibility of amino acids in growing pigs. Anim feed Science and Technology 140:385-401 (2008).
12 Yin YL, Huang CH, Wu X, Li TJ, Huang RL, Kang P, Hu Q, Chu WY and Kong XF, Nutrient digestibility response to graded dietary levels of sodium chloride in weanling pigs. Journal of the Science of Food and Agriculture 88:940-944 (2008).
13 Li TJ, Dai QZ, Yin YL, Zhang J, Huang RL, Ruan Z, Deng Z and Xie M, Dietary starch sources affect net portal appearance of amino acids and glucose in growing pigs. Animal 2:723-729 (2008).
14 Liu YL, Lu J, Shi JX, Hou YQ, Zhu HL, Zhao SJ, Liu HM, Ding BY, Yin YL and Yi GF, Increased expression of the peroxisome proliferator-activated receptor ? in the immune system of weaned pigs after Escherichia coli lipopolysaccharide injection. Veterinary Immunology and Immunopathology 124:82-92 (2008).
15 Hou ZP, Yin YL, Huang RL, Li TJ, Hou RQ, Liu YL, Wu X, Liu ZQ, Wang WC, Xiong H, Wu GY and Tan LX, Rice protein concentrate partially replaces dried whey in the diet for early-weaned piglets and improves their growth performance. J Sci Food Agric 88:1187-1193 (2008).
16 Kang P, Yin YL, Ruan Z, Pan J, Hu Q, Deng ZY, Xiong H and Xie MY, Effect of replacement of lactose with partially hydrolysed rice syrup on small intestine development in weaned pigs from 7 to 21days. Journal of the Science of Food and Agriculture 88:1932-1938 (2008).
17 Deng D, Yao K, Chu WY, Li TJ, Huang RL, Yin YL, Liu HQ, Zhang JS and Wu GY, Impaired translation initiation activation and reduced protein synthesis in weaned piglets fed a low-protein diet. Journal of Nutritional Biochemistry 20: 544-552 (2009).
1 8Tan BE, Li XG, Kong XF, Huang RL, Ruan Z, Deng ZY, Xie MY, Shinzato I, Yin YL and Wu G, Dietary L-arginine supplementation enhances the immune status in early-weaned piglets. Amino Acids 37: 323-331 (2009).
19 Yin FG, Liu YL, Yin YL, Kong XF, Huang RL, Li TJ, Wu GY and Hou YQ, Dietary supplementation with Astragalus polysaccharide enhances ileal digestibilities and serum concentrations of amino acids in early weaned piglets. Amino Acids 37: 263-270 (2009).
20 Kong XF, Zhang YZ, Yin YL, Wu GY, Zhou HJ, Tan ZL, Yang F, Bo MJ, Huang RL, Li TJ and Geng MM, Chinese Yam polysaccharide enhances growth performance and cellular immune response in weanling rats. Journal of Science of Food and Agriculture 89(12): 2039-2044 (2009).
21 Liu YL, Shi JX, Lu J, Meng GQ, Zhu HL, Hou YQ, Yin YL, Zhao SJ and Ding BY, Activation of peroxisome proliferator-activated receptor-gamma potentiates pro-inflammatory cytokine production, and adrenal and somatotropic changes of weaned pigs after Escherichia coli lipopolysaccharide challenge. Innate Immunity 15 (3): 169-178 (2009).
22 Li LL, Peng HZ, Zhang B, Wu GY, Yin YL, Yang KM, Li TJ, Li AK, Hou ZP, Zhang P and Liu CY, The effect of dietary addition of a polysaccharide from atractylodes macrophala koidz on growth performance, immunoglobulin concentration and IL-1βexpression in weaned pigs. Journal of Agricultural Science 147：625-631 (2009).
23 Fang J, Yan FY, Kong XF, Ruan Z, Liu ZQ, Huang RL, Li TJ, Geng MM, Yang F, Zhang YZ, Li P, Gong JH, Wu GY, Fan MZ, Liu YL, Hou YQ and Yin YL, Dietary supplementation with Acanthopanax senticosus extract enhances gut health in weanling piglets. Livestock Science 123: 268-275 (2009).
24 Wang WC, Shi CY, Zhang JS, Gu WT, Li TJ, Gen MM, Chu WY, Huang RL, Liu YL, Hou YQ, Li P and Yin YL, Molecular cloning, distribution and ontogenetic expression of the oligopeptide transporter PepT1 mRNA in Tibetan suckling piglets. Amino Acids 37:593-601 (2009).
25 Kong XF, Yin FG, He QH , Liu HJ, Li TJ, Huang RL, Fan MZ, Liu YL, Hou YQ, Li P, Ruan Z, Deng ZY, Xie MY, Xiong H and Yin YL, Acanthopanax senticosus extract as a dietary additive enhances the apparent ileal digestibility of amino acids in weaned piglets. Livest Sci 123: 261-267 (2009).
26 Wang WC, Gu WT, Tang XF, Geng MM, Fan M, Li TJ, Chu WY, Shi CY, Huang RL, Zhang HF and Yin YL, Molecular cloning, tissue distribution and ontogenetic expression of the amino acid transporter b0,+ cDNA in the small intestine of Tibetan suckling piglets. Comparative Biochemistry and Physiology, Part B 154:157-164 (2009).
27 Deng J, Wu X, Bin S, Li TJ, Huang R, Liu Z, Liu Y, Ruan Z, Deng Z, Hou Y and Yin YL, Dietary amylose and amylopectin ratio and resistant starch content affects plasma glucose, lactic acid, hormone levels1and protein synthesis in splanchnic tissues. Zeitschrift für Tierphysiologie, Tierern?hrung und Futtermittelkunde 94: 220-226 (2010).
28 Liu YL, Shi JX, Lu J, Che ZQ, Zhu HL, Hou YQ, Yin YL, Zhao SJ, Ding BY and Liu HM, Up-regulated expression of peroxisome proliferator-activated receptor γ in the hypothalamic–pituitary–adrenal axis of weaned pigs after Escherichia coli lipopolysaccharide challenge.The Veterinary Journal 184:230-235 (2010).
29 Kang P, Toms D, Yin YL, Cheung Q, Gong JH, Lange KD and Li JL, Epidermal Growth Factor-Expressing Lactococcus lactis Enhances Intestinal Development of Early-Weaned Pigs. J Nutr 140: 806-811 (2010).
30 Yin FG, Zhang ZZ, Huang J and Yin YL, Digestion rate of dietary starch affects systemic circulation of amino acids in weaned pigs. British Journal of Nutrition 103: 1404–1412 (2010).
31 Tan BE, Yin YL, Kong XF, Li P, Li XL, Gao HJ, Li XG, Huang RL and Wu GY, L-Arginine stimulates proliferation and prevents endotoxin-induced death of intestinal cells. Amino Acids 38: 1227-1235 (2010).
32 Tan BE, Yin YL, Liu ZQ, Tang WJ, Xu HJ, Konga XF, Li XG, Yao K, Gu WT, Smith SB and Wu GY, Dietary L-arginine supplementation differentially regulates expression of fat-metabolic genes in porcine adipose tissue and skeletal muscle. J Nutr Bioc. 22:441-445（2011）
33 Yin YL, Huang RL, Li TJ, Ruan Z, Xie MY, Deng ZY, Hou YQ and Wu GY, Amino acid metabolism in the portal-drained viscera of young pigs: effects of dietary supplementation with chitosan and pea hull. Amino Acids 39: 1581–1587 (2010).
34 Wu X, Yin YL, Li TJ, Wang L, Ruan Z, Liu ZQ and Hou YQ, Dietary supplementation with l-arginine or N-carbamylglutamate enhances intestinal growth and heat shock protein-70 expression in weanling pigs fed a corn- and soybean meal-based diet. Amino Acids 39: 831-839 (2010).
35 Yin YL, Yao K, Liu ZJ, Gong M, Ruan Z, Deng D, Tan BE, Liu ZQ, Wu GY, Supplementing L-leucine to a low-protein diet increases tissue protein synthesis in weanling pigs. Amino Acids 39:1477–1486 (2010).
36 Hou YQ, Wang L, Ding BY, Liu YL, Zhu HL, Liu J, Li YT, Wu X, Yin YL, Wu GY, Dietary a-ketoglutarate supplementation ameliorates intestinal injury in lipopolysaccharide-challenged piglets. Amino Acids 39: 555-564 (2010).
37 Chung HJ, Liu Q, Wang RL, Yin YL and Li AK, Physicochemical properties and in vitro starch digestibility of cooked rice from commercially available cultivars in Canada. Cereal Chemistry 87: 297-304 (2010).
38 Wu X, Yin YL, Li TJ, Wang L, Ruan Z, Liu ZQ and Hou YQ, Dietary protein, energy and arginine affect LAT1 expression in forebrain white matter differently. Animal 4: 1518–1521 (2010).
39 Yin YL and Tan BE, Manipulation of dietary nitrogen, amino acids and phosphorus to reduce environmental impact of swine production and enhance animal health. Journal of Food, Agriculture & Environment. 8: 447-462 (2010).
40 Tang ZR, Zhang YM, Stewart AF, Geng MM, Tang XS, Tu Q, Yin YL, High-level expression, purification and antibacterial activity of bovine lactoferricin and lactoferrampin in Photorhabdus luminescens. Protein Expression and Purification 73:132-139 (2010).
41Yu J, Yin P, Yin J, Liu F, Zhu X, Cheng G, Guo K, Yin Y, Xu J, Involvement of ERK1/2 signalling and growth related molecules’ expression in response to heat stress induced damage in rat jejunum and IEC cells. International Journal of Hyperthermia, 2010, 26 (6): 538-555.
42 Yang CB, Albin DM, Wang ZR, Stoll B, Lackeyram D, Swanson KC, Yin YL, Tappenden KA, Mine Y, Yada RY, Burrin DG, and Fan MZ, Apical Na+-D-glucose co-transporter 1 (SGLT1) activity and protein abundance are expressed along the jejunal crypt-villus axis in the neonatal pig. Am J Physiol Gastrointest Liver Physiol 300: G60–G70, 2011.
43 Hou YQ, Wang L, Ding BY, Liu YL, Zhu HL, Liu J, Li YT, Kang P, Yin YL, Wu GY, Alpha-Ketoglutarate and intestinal function. Frontiers in Bioscience 16:1186-1196 (2011).
44 Yao K, Fang J, Yin YL, Feng ZM, Tang ZR, Wu GY, Tryptophan metabolism in animals: important roles in nutrition and health. Frontiers in Bioscience S3:286-297 (2011).
45 Kong XF, Wu GY, Yin YL, Roles of phytochemicals in amino acid nutrition. Frontiers in Bioscience S3:372-384 (2011).
46 He QH, Ren PP, Zhao F, Kong XF, Wu GY, Yin YL, Metabonomics and its role in amino acid nutrition research. Frontiers in Bioscience 16, 2451-2460, June 1, 2011
47 Yao K, Guan S, Li TJ, Huang RL, Wu GY, Ruan Z and Yin YL, Dietary L-arginine supplementation enhances intestinal development and expression of vascular endothelial growth factor in weanling piglets. British Journal of Nutrition 105: 703–709 (2011).
48 Geng MM , Li TJ, Kong XF, Song XY, Chu WY, Huang RL, Yin YL , Wu GY, Reduced expression of intestinal N-acetylglutamate synthase in suckling piglets: a novel molecular mechanism for arginine as a nutritionally essential amino acid for neonates. Amino Acids. 40 ：1513- 1522 (2011).
49. Li Fengna, Yulong Yin, Bie Tan, Xiangfeng Kong, and Guoyao Wu. Leucine nutrition in animals and humans: mTOR signaling 3 and beyond. Amino Acids 41: 1185-1193 (2011).
50 Yin,Fugui Yulong Yin, Zhenzhen Zhang, Mingyong Xie, Ju Huang, Ruilin Huang and Tiejun Li, Digestion rate of dietary starch affects the systemic circulation of lipid profiles and lipid metabolism-related gene expression in weaned pigs. British Journal of Nutrition, 106, 369–377 (2011).
51. He Qinghua, Tang Huiru, Ren Pingping, Kong Xiangfeng, Wu Guoyao, Yin Yulong and Wang Yulan. Dietary Supplementation with L -Arginine Partially Counteracts Serum Metabonome Induced by Weaning Stress in Piglets. Journal of Proteome Research. 10:5214-5221 (2011).
52. Li Fengna, Huansheng Yang, Yehui Duan and Yulong Yin. Myostatin regulates preadipocyte differentiation and lipid metabolism of adipocyte via ERK1/2. Cell Biol Int 35(11):1141-1146 (2011).
53. Li F. N, L. L. Li, H. S. Yang, X. X. Yuan, B. Zhang, M. M. Geng, C. W. Xiao and Y. L. Yin. Regulation of soy isoflavones on weight gain and fat percentage: evaluation in a Chinese Guangxi minipig model.Animal 5:1903-1908 (2011).
147. Yao Kang, Lei Wang, Binying Ding, Dabo Fu, Yulan Liu, Huiling Zhu, Jian Liu, Yongtang Li, Ping Kang, Yu-long Yin, Guoyao Wu, Yongqing Hou. Alpha-ketoglutarate inhibits glutamine degradation and enhances protein synthesis in intestinal porcine epithelial cells. Amino Acids. 2012 Jun ;42 (6):2491-500
54. Yang Huansheng, Fengna Li, Xiangfeng Kong, Xiaoxue Yuan, Guoqi Lian, Meimei Geng, Tiejun Li, Jingdong Yin and Yulong Yin. Molecular cloning, tissue distribution and ontogenetic expression of Xiang pig Chemerin and its involvement in regulating energy metabolism through Akt and ERK1/2 signaling pathways. Mol Biol Rep 39(2):1887-1894 (2012).
55. He Qinghua, Pingping Ren, Xiangfeng Kong, Yongning Wu, Guoyao Wu, Peng Li, Fuhua Hao,Huiru Tang, Yulong Yin. Comparison of serum metabolite compositions between obese and lean growing pigs. Journal of Nutritional Biochemistry 23: 133¨139 (2012).
56. Tan Bie, Li Xinguo, Yin Yulong, Wu Zhenlong, Liu Chuang, Tekwe D. Carmen, Wu Guoyao. Regulatory roles for L-arginine in reducing white adipose tissue. Frontiers in Bioscience. 17: 2237-2246 (2012).
57. Kong X F, Y.L.Yin, G.Y.Wu. Arginine stimulates the mTOR signaling pathway and protein synthesis in porcine trophectoderm cells. Journal of Nutritional Biochemistry 23 1178-1183 (2012).
58. Liu X.D，X.Wu, Y.L.Yin, Y.Q.Liu, M.M.Geng, H.S.Yang G.Y.Wu. 2011. Effects of dietary L-arginineor N-carbamylglutamate supplementation during late gestation of sows on the miR-15b/16, miR-221/222,VEGFAandeNOSexpression in umbilicalvein. Amino Acids 42:2111-2119 (2012).
59. Ren Wenkai, Yulong Yin, Gang Liu, Xinglong Yu, Yinghui Li, Guan Yang, Teijun Li, Guoyao Wu. Effect of dietary arginine supplementation on reproductive performance of mice with porcine circovirus type 2 (PCV2) infection" Amino Acids 42:2089-2094 (2012).
60. Wu X. Wu , Y.L. Yin, Y.Q. Liu, X.D. Liu, Z.Q. Liu, T.J. Li, R.L. Huang, Z. Ruan, Deng Z. Effect of dietary arginine and N-carbamoylglutamate supplementation reproduction and gene expression of eNOS, VEGFA and PlGF1 in on in late pregnancy of sows placenta. Animal Reproduction Science. 132 187-192 (2012).
61. Yang Huansheng, Dezhi Fu., Hua Shao, Xiangfeng Kong, Wence Wang, Xiaojian Yang, Charles M. Nyachoti, Yulong Yin. Impacts of Birth Weight on Plasma, Liver and Skeletal Muscle Neutral Amino Acid Profiles and Intestinal Amino Acid Transporters in Suckling Huanjiang Mini-Piglets. PLOS ONE 7:e50921 (2012).
62. Yang Huansheng, YulongYin. Chemerin regulates proliferation and differentiation of myoblast cells via ERK1/2 and mTOR signaling pathways. Cytokine 60:646-652 (2012).
62. Zhou Xihong , Xin Wu, Yulong Yin, Cui Zhang, Liuqin He. Preventive oral supplementation with glutamine and arginine has beneficial effects on the intestinal mucosa and inflammatory cytokines in endotoxemic rats. Amino Acids 43: 813-821 (2012).
63. Yang Huansheng, YulongYin. Soy isoflavones modulate adipokines and myokines to regulate lipid metabolism in adipose tissue, skeletal muscle and liver of male Huanjiang mini-pigs. Molecular and Cellular Endocrinology 365 44-51 (2012).
64.Tan BE, Li XG, Wu GY, Yulong Yin 2012. Dynamic changes in blood flow and oxygen consumption in the portal-drained viscera of growing pigs receiving acute administration of L-arginine. Amino Acids, 43: 2481-2489.
65 Wu Xin,, Yuzhe Zhang , Yulong Yin , Zheng Ruan , Huimin Yu , Zhenlong Wu , Guoyao Wu. Roles of heat-shock protein 70 in protecting against intestinal mucosal damage . Frontiers in Bioscience 18, 356-365, January 1, 2013
66 He Liuqin, Yulong Yin, Tiejun Li, Rulin Huang，Zhenlong Wu, Guoyao Wu。Use of the Ussing chamber technique to study nutrient transport by epithelial tissues。. Frontiers in Bioscience
66 Wu Xin, Y. Zhang, Z. Liu, T. Li, Y. Yin. Effects of oral supplementation with glutamate or combination of glutamate and N-carbamylglutamate on intestinal mucosa in piglets. Journal of Animal Science, 90: 337–339, 2012
编著(主编)
1. 印遇龙主编《猪营养代谢与调控研究》湖南科学技术出版社，2011
2. 印遇龙主编. 《现代仔猪营养学》中国农业出版社，2010
3．印遇龙主编《猪氨基酸营养与代谢》科学出版社，2008.014.
4.Nutritional and physiological functions of amino acids in swine, 2013.Springer (德国施普林格出版社）.
