教授、博士生导师 湖南大学“岳麓****”
研究领域：分析化学、生物功能材料和纳米医学
电子邮件：cairen@hnu.edu.cn
欢迎有志的本科生、硕士生、博士生和博士后加盟。






基本信息
蔡仁，男，毕业于美国佛罗里达大学，获分析化学博士学位，师从谭蔚泓教授。现任湖南大学材料科学与工程学院教授，博士生导师。目前主要从事分析化学、纳米生物材料的设计合成与肿瘤诊疗、生物传感器与器件测试研究。至今发表SCI学术论文40余篇，其中包括在J. Am. Chem. Soc.，Anal. Chem.等国际顶级学术期刊发表一作或通讯作者论文24篇，相关研究成果被C&EN等知名媒体所报道。合作申请发明专利2项。获得湖南省自然科学基金优秀青年基金资助。另外，兼任Energies 杂志(IF 2.7)专题编辑（Topic Editor）。
联系方式：cairen@hnu.edu.cn


教育背景
2013—2017佛罗里达大学(美国) 化学系 博士


工作履历
2019.4— 2019.10 访问研究员， 佛罗里达大学 (美国) 化学系

2019.1— 2019.3 博士后研究员，西北太平洋国家实验室(美国) 材料科学研究室

2018.10— 2019.1 访问研究员， 基础科学研究所(韩国 蔚山)软体和活性材料研究中心

2018.1— 2018.12 博士后研究员，佛罗里达大学(美国) 化学系

2011.8—2013.8 研究助理， 南洋理工大学(新加坡)材料科学与工程学院


学术兼职
兼任Energies 杂志(IF 2.7)专题编辑(Topic Editor)
研究领域
分析化学
生物纳米材料的设计合成及在癌症治疗和生物成像中的应用
生物传感器与器件测试




学术成果
Publications
44. Chengyi Hong, Lingling Chen, Chenyue Wu, Dan Yang, Jia-Yong Dai, Zhiyong Huang,Ren Cai,*and Weihong Tan.Green synthesis of Au@WSe₂ hybrid nanostructures with the enhanced peroxidase-like activity for sensitive colorimetric detection of glucose.Nano Research2021.
43.Zuocai Zhang, Dan Yang, Shaorong Lu,* Ren Cai,* and Weihong Tan, Rapid Water-responsive Shape Memory Films for Smart Resistive Bending Sensors, Nano Today2021, 38, 101202
42.Chengyi Hong, Xiaoxia Zhang, Sishi Ye, Hongfen Yang, Zhiyong Huang,* Dan Yang,* Ren Cai,* and Weihong Tan, Aptamer-Pendant DNA Tetrahedron Nanostructure Probe for Ultrasensitive Detection of Tetracycline by Coupling Target-Triggered Rolling Circle Amplification. ACS Applied Materials & Interfaces 2021, 13, 17, 19695–19700.
41. Zuocai Zhang, Dan Yang, Hongfen Yang, Yuqi Li, Shaorong Lu,* Ren Cai,* and Weihong Tan.A hydrophobic sisal cellulose microcrystal film for fire alarm sensors. Nano Lett. 2021,21, 5, 2104–2110.
40.Jia Ge, Jian-Hua Yu, Hongfen Yang, Dan Yang* and Ren Cai,* Human serum albumin templated MnO₂ nanosheets as an efficient biomimetic oxidase for biomolecule sensing. Journal of Materials Chemistry B 2020, 8, 11090-11095.
39.Chengyi Hong, Xiaoxia Zhang, Chenyue Wu, Qin Chen, Hongfen Yang*, Dan Yang*, Zhiyong Huang, Ren Cai,* and Weihong Tan*, On-Site Colorimetric Detection of Cholesterol Based on Polypyrrole Nanoparticles. ACS Applied Materials & Interfaces 2020, 12 (49), 54426-54432.
38. Jia Ge, Yun Hu, Ruijie Deng, Zhaohui Li, Kaixiang Zhang, Muling Shi, Dan Yang,* Ren Cai,* and Weihong Tan.* Highly sensitive microRNA detection by coupling nicking-enhanced rolling circle amplification with MoS₂ quantum dots. Analytical Chemistry2020, 92, 19, 13588–13594.
37. Xigao Chen, Liping Qiu, Ren Cai, Cheng Cui, Long Li, Jian-Hui Jiang, Weihong Tan. Aptamer-Directed Protein-Specific Multiple Modifications of Membrane Glycoproteins on Living Cells. ACS Applied Materials & Interfaces2020, 12, 34, 37845–37850.
36. Yu Yang, Wenjun Zhu, Liang Cheng,Ren Cai, Xuan Yi, Jiaxuan He, Xiaoshu Pan, Lu Yang, Kai Yang, Zhuang Liu, Weihong Tan, Meiwan Chen. Tumor microenvironment (TME)-activatable circular aptamer-PEG as an effective hierarchical-targeting molecular medicine for photodynamic therapy. Biomaterials2020, 119971.
35.Ren Cai, Haiyan Jin, Dan Yang, Keng-Te Lin, Jianke Sun, Zhuo Chen, Xiaobing Zhang, and Weihong Tan.* Generalized Preparation of Au NP@Ni(OH)₂ Yolk-Shell Nanoparticles and Their Superior Catalytical Activity for Oxygen Evolution Reaction. Nano Energy2020, 104542.
34. Ren Cai, Dan Yang, Xigao Chen, Yifan Lyv, He Zhen, Kangfu Chen, Yu Yang, Liqin Zhang, Jia Ge, Lian Xia, Yuliang Zhao, Weihong Tan.* 3D Halos Assembled from Fe₃O₄/Au NPs with Enhanced Catalytic and Optical Properties. Nanoscale2019,11 (43), 20968-20976.
33. Ren Cai, Yaping Du, Dan Yang, Guohua Jia, Bowen Zhu, Yifan Lyu, Liping Qiu, Xigao Chen, Dechao Chen, Wei Chen, Liqin Zhang, Meng Luo,Lu Yang, Yuliang Zhao, Weihong Tan.* Free-standing 2D nanorafts by assembly of 1D nanorods for biomolecule sensing. Nanoscale2019,11, 12169-12176.
32. Ren Cai, Dan Yang, Yifan Lyu, Bowen Zhu, Zhen He, Yusuke Kitamura, Liping Qiu, Xigao Chen, Yuliang Zhao, Weihong Tan.* Generalized preparation of 2D quasi-nanosheets via self-assembly of nanoparticles.Journal of the American Chemical Society2019, 141, 1725-1734.
31. Ren Cai, Dan Yang, Liang Yan, Feng Tian, Jichao Zhang, Yifan Lyv, Kangfu Chen, Chengyi Hong, Xigao Chen, Yuliang Zhao, Zhuo Chen, Weihong Tan.* Free-floating 2D Nanosheets With Superlattice Assembled From Fe₃O₄ Nanoparticles. ACS Applied Nano Materials2018, 1 (10), 5389-5395.
30. Ren Cai, D. Yang, X. Chen, Y. Huang, Y. Lyv, J. He, M. Shi, I-T. Teng, S. Wan, W. Hou, Weihong Tan.* Three Dimensional Multipod Superstructure based on Cu(OH)₂ as a Highly Efficient Nanozyme.J. Mater. Chem. B2016, 4, 4657-4661.
29. Ren Cai, D. Yang, S. Peng, X. Chen, Y. Huang, Y. Liu, W. Hou, S. Yang, Z. Liu, and Weihong Tan.* Single Nanoparticle to 3D Supercage: Framing for an Artificial Enzyme System.Journal of the American Chemical Society2015, 137, 13957-13963. (C&EN NEWS, http://cen.acs.org/articles/93/web/2015/10/Tiny-Boxes-Hold-Catalytic-Surprise.html).
28. Ren Cai, D. Yang, L. Zhang, J. Wu,X. Chen,Z. Zhang, H. Huo, Q. Yan, Weihong Tan,* Fabrication of ultrathin Zn(OH)₂ nanosheets as drug carriers. Nano Research 2016, 9: 250, doi:10.1007/s12274-016-1138-2 (EurekAlert! Science News (AAAS), http://underfringe55.rssing.com/browser.php?indx=**&last=1&item=19).
27. Ren Cai, D. Yang, L. Zhang, L. Qiu, H. Liang, X. Chen, Z. Zhang, S. Cansiz, S. Wan, Q. Yan, Weihong Tan,* A facile process for the preparation of three-dimensional (3D) hollow Zn(OH)₂ nanoflowers at room temperature.Chemistry-A European Journal 2016, 22(32): 11143-11147 (Hot Paper, Spotlight by Angew. Chem. Int. Ed. DOI: 10.1002/anie).
26. Ren Cai, Y. Du, S. Peng, H. Bi, W. Zhang, D. Yang, J. Chen, T. M. Lim, H. Zhang, Q. Yan,The Synthesis of Porous Metal MCO₃ (M=Mn, Co, Ca) Hollow Microstructures and Adsorption Property Thereof. Chemistry- A European Journal2014,20(2): 421-425.
25. Ren Cai, J. Chen,D. Yang,Z. Zeng, S. Peng, J. Wu, W. Zhang, C. Zhu,T. -M. Lim, H. Zhang, Q. Yan, Solvothermal-induced Conversion of One-Dimensional Multi-layer Nanotubes to Two-Dimensional Hydrophilic VO_x Nanosheets: Synthesis and Water Treatment Application. ACS Appl. Mater. Interfaces 2013, 5(20): 10389-10394.
24. Ren Cai, Y. Du, W. Zhang, H. Tan, T. Zeng,X. Huang, H. Yang, C. Chen, H. Liu, J. Zhu, S. Peng, J. Chen, Y. Zhao, H. Wu,Y. Huang, R. Xu, T. -M. Lim, Q. Zhang, H. Zhang, Q. Yan, Synthesis of Porous Amorphous FePO₄ Nanotubes and Their Li Storage Properties. Chemistry-A European Journal 2013, 19(5): 1568-1572.
23. Ren Cai, H. Li, W. Zhang, H. Tan, D. Yang, H. H. Hng, T. M. Lim, Q. Yan, Controlled Synthesis of Double-wall a-FePO₄ Nanotubes and Their LIB Cathode Properties. Small, 2013, 9(7): 1036-1041.
22. Ren Cai, J. Chen, J. Zhu, C. Xu, W. Zhang, C. Zhang, W. Shi, H. Tan, D. Yang, H. H. Hng, T. M. Lim, Q. Yan, Synthesis of Cu_xS/Cu Nanotubes and Their Lithium Storage Properties. Journal of Physical Chemistry C2012, 116 (23), 12468-12474.
21. Ren Cai, B. Deng, H. Jiang，Y. Yu，M. Yu，L. Li，J. Li. Radiation Induced Graft Polymerization of a Fluorinated Acrylate onto Fabric. Radiation Physics and Chemistry2012, 81 (9), 1354-1356.
20. B. Deng ^#, Ren Cai^#, Y. Yu, H. Jiang, C. Wang, J. Li, L. Li, M. Yu, J. Li, L. Xie, Q. Huang, C. Fan. Laundering Durability of Superhydro-phobic Cotton Fabric. Advanced Materials 2010, 22 (48), 5473-5477.
19. J. Ge^#, Ren Cai^#, L. Yang, L. Zhang, Y. Jiang, Y. Yang, C. Cui, S. Wan, X. Chu, Weihong Tan.* Core-Shell HA-Au NPs@Si NPs Nanoprobe for Sensitive Fluorescence Hyaluronidase Detection and Cell Imaging. ACS Sustainable Chemistry & Engineering 2018, 6 (12), 16555-16562.
18. J. Ge, Ren Cai, X. Chen, Q. Wu, L. Zhang, Y. Jiang, C. Cui, S. Wan, W. Tan. Facile approach to prepare HSA-templated MnO₂ nanosheets as oxidase mimic for colorimetric detection of glutathione. Talanta2019, 195, 40-45.
17. Yifan Lyu, Yian Guo, Ren Cai, Ruizi Peng, Chengyi Hong, Xigao Chen, Weijia Hou, Xiaowei Li, Jie Tan, Yuxiu Zou, Xiaobing Zhang, Qiaoling Liu, Weihong Tan. Spherically Directed Synthesis and Enhanced Cellular Internalization of Metal-Crosslinked DNA Micelles. Chem2019, 5 (4), 913-928.
16. L. Yang, H. Sun, Y. Liu, W. Hou, Y. Yang, Ren Cai, C. Cui, P. Zhang, X. Pan, X. Li, L. Li, B. S Sumerlin, Weihong Tan. Self‐Assembled Aptamer‐Grafted Hyperbranched Polymer Nanocarrier for Targeted and Photoresponsive Drug Delivery. Angew. Chem. Int. Ed.2018, 57 (52), 17048-17052.
15. X. Li, C A. Figg, R. Wang, Y. Jiang, Y. Lyu, H. Sun, Y. Liu, Y. Wang, I-T. Teng, W. Hou, Ren Cai, C. Cui, L. Li, X. Pan, B. S Sumerlin, W. Tan. Cross‐Linked Aptamer–Lipid Micelles for Excellent Stability and Specificity in Target‐Cell Recognition.Angew. Chem. Int. Ed.2018,130 (36), 11763-11767.
14. Y. Lyu, I-T. Teng, L. Zhang, Y. Guo, Ren Cai, X. Zhang, L. Qiu, W. Tan. A comprehensive regression model for dissociation equilibria of cell-specific aptamers. Anal. Chem.2018, 90, 10487-10493.
13. Lyu, Y.; Wu, C.; Heinke, C.; Han, D.; Cai, Ren; Teng, I. T.; Liu, Y.; Liu, H.; Zhang, X.; Liu, Q.; Tan, W., Constructing Smart Protocells with Built-In DNA Computational Core to Eliminate Exogenous Challenge. Journal of the American Chemical Society 2018, 140 (22), 6912-6920.
12. Y. Huang, H. C. Pappas, L. Zhang, S. Wang,Ren Cai, W. Tan, S. Wang, D. G. Whitten, and K. S. Schanze, Selective Imaging and Inactivation of Bacteria over Mammalian Cells by Imidazolium Substituted Polythiophene, Chemistry of Materials2017, 29 (15), 6389–6395.
11. S. Wang, L. Zhang, S. Wan, S. Cansiz, C. Cui, Y. Liu, Ren Cai, C. Hong, I-T. Teng, M. Shi, Y. Wu, Y. Dong, and W. Tan, Apta-sensor with Expanded Nucleotide Using DNA Nanotetrahedra for Electrochemical Detection of Cancerous Exosomes, ACS Nano2017, 11 (4), 3943–3949.
10. Y. Wang, C. Wu, T. Chen, H. Sun, S. Cansiz, L. Zhang, C. Cui, W. Hou, Y. Wu, S. Wan, Ren Cai, Y. Liu, B. Sumerlin, X. Zhang, W. Tan, DNA micelle flares: a study of the basic properties that contribute to enhanced stability and binding affinity in complex biological systems, Chemical Sciences 2016, 7, 6041-6049.
9. X. Zhang, J. Ge, Y. Xue, B. Lei, D. Yan, N. Li, Z. Liu, Y. Du, Ren Cai, Controlled Synthesis of Ultrathin Lanthanide Oxide Nanosheets and Their Promising pH-Controlled Anticancer Drug Delivery. Chemistry - A European Journal 2015, 21 (34), 12204-12204. (Back Cover)
8. S. Cansiz, L. Zhang, C. Wu, Y. Wu, I. T. Teng, W. Hou, Y. Wang, S. Wan,Ren Cai, C. Jin, Q. Liu, W. Tan, DNA Aptamer Based Nanodrugs: Molecular Engineering for Efficiency. Chemistry - An Asian Journal2015, 24 (15), 2155-2162.
7. S. Peng, L. Li, H. Tan, Ren Cai, W. Shi, C. Li, S. Ramakrishna, M. Srinivasan, S. G. Mhaisalkar, Q. Yan, MS₂ (M= Co and Ni) Hollow Spheres with Tunable Interiors for High-performance Supercapacitors and Photovoltaics. Adv. Funct. Mater.2014, 24 (15), 2155-2162.
6. X. Zhou, G. Wu, J. Wu, H. Yang, J. Wang, G. Gao, Ren Cai, Q. Yan, Multiwall carbon nanotubes-V₂O₅ integrated composite with nanosized architecture as cathode material for high performance lithium ion batteries. J. Mater. Chem. A 2013, 1, 15459-15468.
5. S. Peng, L. Li, C. Li, H. Tan, Ren Cai, H. Yu, S. Mhaisalkar, M. Srinivasan, S. Ramakrishna, Q. Yan, In situ growth of NiCo₂S₄ nanosheets on graphene for high-performance supercapacitors. Chem. Commun.2013, 49, 10178-10180.
4. X. Huang, J. Chen, H. Yu, Ren Cai, S. Peng, H. H. Hng, Q. Yan, Carbon buffered-transition metal oxide nanoparticle-graphene hybrid nanosheets as high-performance anode materials for lithium ion batteries. J. Mater. Chem. A 2013, 1,6901-6907.
3. S. Peng, L. Li, H. Tan, Y. Wu, Ren Cai, X. Huang, P. Zhu, S. Ramakrishna,M. Srinivasan, S. G. Mhaisalkar, Q. Yan, Monodispersed Ag nanoparticles loaded on the PVP-assisted synthetic Bi₂O₂CO₃ microspheres with enhanced photocatalytic and supercapacitive performances. J. Mater. Chem. A 2013, 1, 7630-7638.
2. D. Yang, J. Zhu, X. Rui, H. Tan, Ren Cai, H. E. Hoster, D. Y. W. Yu, H. H. Hng, Q. Yan, Synthesis of Cobalt Phosphides and Their Application as Anodes for Lithium Ion Batteries. ACS Appl. Mater. Interfaces2013, 5(3): 1093-1099.
1. X. Huang, J. Chen, H. Yu, S. Peng, Ren Cai,Q. Yan, H. H. Hng, Immobilization of plant polyphenol stabilized-Sn nanoparticles onto carbon nanotubes and their application in rechargeable lithium ion batteries. RSC Adv. 2013, 3(16): 5310-5313.


奖励与荣誉
湖南省自然科学基金优秀青年基金