暂无信息



基本信息
教授，博士生导师

Email: zpchen@hnu.edu.cn

教育背景
2002.10-2008.11 英国钮卡斯尔大学化工与先进材料学院，博士后。
1998.09-2001.05 湖南大学化学化工学院，理学博士；
1995.09-1998.06 湖南大学化学化工学院，理学硕士；
1991.09-1995.06 湖南大学化学化工学院，理学学士；


工作履历
2008.12- 现在 湖南大学化学化工学院，教授、博士生导师。
2001.06- 2002.09 湖南大学化学化工学院，讲师。


学术兼职
英国斯特斯克莱德大学（University of Strathclyde）纯粹与应用化学系荣誉教师
Editorial Advisory Board Member of "Chemometrics and Intelligent Laboratory Systems"
研究领域
目前主要从事复杂体系波谱定量分析理论和应用方面的研究，研究内容主要包括：复杂生物体系质谱定量分析技术、表面增强拉曼光谱定量分析技术、荧光化学生物传感技术、化学计量学理论和方法等。所获得的研究成果可望为临床疾病诊断、生物医学研究、食品和药品安全检测、以及环境监测和保护等领域提供重要的工具。
科研项目
1. 国家自然科学基金，基于分子探针技术的化学计量学定量分析理论及其应用研究，2018.1-2021.12。
2. 国家自然科学基金，非均相体系荧光化学生物传感技术中的化学计量学理论及应用研究，2015.1-2018.12。
3. 国家自然科学基金，具有普适性的表面增强拉曼光谱定量分析技术的研究，2013.1-2016.12。
4. 国家自然科学基金，复杂多相体系拉曼光谱定量分析的化学计量学方法研究，2011.1-2013.12。
5.科技部重大科学仪器设备开发专项子任务，SHINERS粒子模型设计与理论研究，2011.9-2015.8。
6. 湖南省自然科学基金，复杂非均相体系荧光化学生物传感定量分析理论及应用研究，2016.1-2017.12。
7.教育部博士点基金（博导类），复杂非均相体系原位光谱定量分析基础理论研究，2014.1-2016.12。
8.教育部新世纪人才计划，化学计量学，2013.1-2014.12。
学术成果
主要科研论文：
Shi, C.X.; Chen, Z.P.*; Chen, Y.; Liu, Q.; Yu, R.Q. Quantification of dopamine in biological samples by surface-enhanced Raman spectroscopy: comparison of different calibration models, Chemometrics and Intelligent Laboratory Systems, 2017, 169, 87-93
Zuo, Q.; Xiong, S.; Chen, Z.P.*; Chen, Y.; Yu, R.Q. A novel calibration strategy based on background correction for quantitative circular dichroism spectroscopy, Talanta, 2017, 174, 320-324
Kong, J.J.; Chen, Z.P.*; Chen, Y.; Yan, X.F.; Yu, R.Q. Direct DNA quantification in cell lysates by fluorometric method in combination with an advanced chemometric model, Chemometrics and Intelligent Laboratory Systems, 2016, 151, 9-14
Hu, Y.L.; Chen, Z.P.*; Chen, Y.; Shi, C.X.; Yu, R.Q. Generalized multiple internal standard method for quantitative liquid chromatography mass spectrometry, Journal of Chromatography A, 2016,1445, 112-117
Yan, X.F.; Chen, Z.P.*; Cui, Y.Y.; Hu, Y.L.; Yu, R.Q. Quantitative generalized ratiometric fluorescence spectroscopy for turbid media based on probe encapsulated by biologically localized embedding, Analytica Chimica Acta, 2016, 921, 38-45
Chen, Y.; Chen, Z.P.*; Zuo, Q.; Shi, C.X.; Yu, R.Q. Surface-enhanced Raman spectroscopy based on conical holed enhancing substrates, Analytica Chimica Acta, 2015, 887, 45-50
Yan, X.F.; Chen, Z.P.*; Kong, J.J.; Hu, Y.L.; Chen, Y.; Yu, R.Q. Determination of free Mg²⁺ in turbid samples with the coexistence of interfering Ca²⁺ using extended quantitative fluorescence model, Chemometrics and Intelligent Laboratory Systems, 2015, 147, 41-46
Shi, C.X.; Chen, Z.P.*; Chen, Y.; Yu, R.Q. Quantitative analysis of hormones in cosmetics by LC-MS/MS combined with an advanced calibration model, Analytical Methods, 2015, 7, 6804-6809
Long, S.Y.; Chen, Z.P.*; Chen, Y.; Yu, R.Q. Quantitative detection of captopril in tablet and blood plasma samples by the combination of surface-enhanced Raman spectroscopy with multiplicative effects model, Journal of Raman Spectroscopy, 2015, 46, 605-609
Chen, Y.; Chen, Z.P.*; Jin, J.W.; Yu, R.Q. Quantitative determination of ametryn in river water using surface-enhanced Raman spectroscopy coupled with an advanced chemometric model, Chemometrics and Intelligent Laboratory Systems, 2015, 142, 166-171
Chen, Y.; Chen, Z.P.*; Long, S.Y.; Yu, R.Q. Generalized ratiometric indicator based surface-enhanced Raman spectroscopy for the detection of Cd²⁺ in environmental water samples, Analytical Chemistry, 2014, 86, 12236-12242
Du, H.L.; Chen, Z.P.*; Song, M.; Chen, Y.; Yu, R.Q. Novel calibration model maintenance strategy for solving the signal instability in quantitative liquid chromatography–mass spectrometry, Journal of Chromatography A, 2014, 1338, 44-50
Jin, J.W.; Chen, Z.P.*; Song, J.; Xia, T.H.; Yu, R.Q. Determination of glucose in plasma by dry film-based near infrared spectroscopy: correcting the thickness variations of dry films without applying an internal standard, Chemometrics and Intelligent Laboratory Systems, 2014, 135, 63-69
Song, M.; Chen, Z.P.*; Chen, Y.; Jin, J.W. Multiplicative effects model with internal standard in mobile phase for quantitative liquid chromatography-mass spectrometry, Talanta, 2014, 125, 347-351.
Xia, T.H.; Chen, Z.P.*; Chen, Y.; Jin J.W.; Yu, R.Q. Improving the quantitative accuracy of surface enhanced Raman spectroscopy by the combination of microfluidics with a multiplicative effects model, Analytical Methods, 2014, 6, 2363-2370
Song, J.; Chen, Z.P.*; Jin, J.W.; Chen, Y.; Yu, R.Q. Quantitative surface-enhanced Raman spectroscopy based on the combination of magnetic nanoparticles with an advanced chemometric model, Chemometrics and Intelligent Laboratory Systems, 2014, 135, 31-36
Chen, Y.; Chen, Z.P.*; Yang J.; Jin, J.W.; Zhang, J.; Yu, R.Q. Quantitative fluorescence spectroscopy in turbid media: a practical solution to the problem of scattering and absorption, Analytical Chemistry, 2013, 85, 2015-2020
Yang, J.; Chen, Z.P.*; Zhang, J.; Jin, J.W.; Chen, Y. Quantitative Raman spectrometry: the accurate determination of analytes in solution phase of turbid media, Chemometrics and Intelligent Laboratory Systems, 2013, 126, 6-10
Zhang, J.; Liu S.Z.; Yang, J.; Song, M.; Song, J.; Du, H.L.; Chen, Z.P.* Quantitative spectroscopic analysis of heterogeneous systems: chemometric methods for the correction of multiplicative light scattering effects, Review in Analytical Chemistry , 2013, 32(2), 113-125
Chen, Z.P*; Li, L.M.; Jin, J.W.; Nordon, A.; Littlejohn, D.; Yang, J.; Zhang, J.; Yu, R.Q. Quantitative analysis of powder mixtures by Raman spectrometry: the influence of particle size and its correction, Analytical Chemistry, 2012, 84, 4088-4094
Jin, J.W.; Chen, Z.P.*; Li, L.M.; Steponavicius, R.; Thennadil, S.N.; Yang, J.; Yu, R.Q. Quantitative spectroscopic analysis of heterogeneous mixtures: the correction of multiplicative effects caused by variations in physical properties of samples, Analytical Chemistry, 2012, 84, 320-326
Chen Z.P.*; Zhong L.J.; Nordon A.; Littlejohn D.; Holden M.; Fazenda M.; Harvey L.; McNeil B.; O’Kennedy R. Calibration of multiplexed fibre-optic spectroscopy, Analytical Chemistry, 2011, 83, 2655-2659
Chen Z.P.*; Li L.M.; Yu R.Q.; Littlejohn D.; Nordon A.; Morris J.; Dann A.S.; Jeffkins P.A.; Richardson M.D.; Stimpson S.L. Systematic prediction error correction: a novel strategy for maintaining the predictive abilities of multivariate calibration models, Analyst, 2011, 136, 98-106
Chen Z.P.; Lovett D.; Morris J. Process analytical technologies and real time process control a review of some spectroscopic issues and challenges, Journal Process Control, 2011, 21, 1467-1482
Du W.; Chen Z.P.*; Zhong L.J.; Wang S.X.; Yu R.Q.; Nordon A.; Littlejohn D.; Holden M. Maintaining the predictive abilities of multivariate calibration models by spectral space transformation, Analytica Chimica Acta, 2011, 690, 64-70
Chen, Z.P.*; Morris, J. Borissova, A.; Khan, S.; Mahmud, T.; Penchev, R.; Roberts, K. On-line monitoring of batch cooling crystallisation of organic compounds using ATR-FTIR spectroscopy coupled with an advanced chemometric calibration method, Chemometrics and Intelligent Laboratory Systems, 2009, 96, 49-58
Chen, Z.P.; Morris, J. Process analytical technology and compensating for nonlinear effects in process spectroscopic data for improved process monitoring and control, Biotechnology Journal, 2009, 4, 610-619
Chen, Z.P.*; Fevotte, G.; Caillet, A.; Littlejohn, D.; Morris, J. Advanced calibration strategy for in-situ quantitative monitoring of phase transition processes in suspensions using FT-Raman spectroscopy, Analytical Chemistry, 2008, 80, 6658-6665
Chen, Z.P.*; Morris, J. Improving the linearity of spectroscopic data subjected to fluctuations in external variables by the extended loading space standardization, Analyst, 2008, 133, 914-922
Chen, Z.P.; Lovett, D.; Morris, J. Process analytical technologies (PAT)-the impact for process systems engineering, Computer Aided Chemical Engineering, 2008, 25, 967-972
Chen, Z.P.; Morris, J.; Martin, E. Extracting chemical information from spectral data with multiplicative light scattering effects by optical path-length estimation and correction, Analytical Chemistry, 2006, 78, 7674-7681
Chen, Z.P.; Morris, J.; Martin, E. Correction of temperature-induced spectral variations by loading space standardization, Analytical Chemistry, 2005, 77, 1376-1384
Chen, Z.P.; Morris, J.; Martin, E.; Hammond, R.B.; Lai, X.J.; Ma, C.Y.; Purba, E.; Roberts, K.J.; Bytheway, R. Enhancing the signal-to-noise ratio of X-ray diffraction profiles by smoothed principal component analysis, Analytical Chemistry, 2005, 77, 6563-6570
Chen, Z.P.; Morris, J.; Martin, E.; Yu, R.Q.; Liang, Y.Z.; Gong, F. Recursive evolving spectral projection for revealing the concentration windows of overlapping peaks in two-way chromatographic experiments, Chemometrics and Intelligent Laboratory Systems, 2004, 72, 9-19
Chen, Z.P.; Yu, R.Q. Mitigating model deficiency in three-way data analysis by the combination of background constraining and iterative correcting techniques, Analytica Chimica Acta, 2003, 487, 171-180
Chen, Z.P.; Wu, H.L.; Li, Y.; Yu, R.Q. On self-weighted alternating trilinear decomposition algorithm-the property of being insensitive to the excess factors used in calculation, Journal of Chemometrics, 2001, 15, 427-438
Chen, Z.P.; Li, Y.; Yu, R.Q. Pseudo alternating least squares algorithm for trilinear decomposition, Journal of Chemometrics, 2001, 15, 149-167
Chen, Z.P.; Liu, Z. Cao, Y. Z.; Yu, R.Q. Efficient way to estimate the optimum number of factors for trilinear decomposition, Analytica Chimica Acta, 2001, 444, 295-307
Chen, Z.P.; Wu, H.L.; Jiang, J.H.; Li, Y.; Yu, R.Q. A novel trilinear decomposition algorithm for second orders linear calibration, Chemometrics and Intelligent Laboratory Systems, 2000, 52, 75-86
Chen, Z.P.; Wu, H.L.; Li, Y.; Yu, R.Q. Novel constrained PARAFAC algorithm for second order linear calibration, Analytica Chimica Acta, 2000, 423, 187-196
Chen, Z.P.; Jiang, J.H.; Li, Y.; Liang, Y.Z.; Yu, R.Q. Fuzzy linear discriminant analysis for chemical data sets, Chemometrics and Intelligent Laboratory Systems, 1999, 45, 295-302
Chen, Z.P.; Jiang, J.H.; Li, Y.; Yu, R.Q. Non-linear mapping using real-valued genetic algorithm, Chemometrics and Intelligent Laboratory Systems, 1999, 45, 409-418
Chen, Z.P.; Liang, Y.Z.; Jiang, J.H.; Li, Y.; Qian, J.Y.; Yu, R.Q. Determination of the number of components in mixtures using a new approach incorporating chemical information, Journal of Chemometrics, 1999, 13, 15-30
Chen, Z.P.; Jiang, J.H.; Li, Y.; Shen, H.L.; Liang, Y.Z.; Yu, R.Q. Smoothed window factor analysis, Analytica Chimica Acta, 1999, 381, 233-246

发明专利：
陈增萍、俞汝勤. 用于维护复杂体系光谱校正模型预测能力的方法, 中国发明专利, 专利号：ZL4.0（2012.05.23）
陈增萍、金竞文、俞汝勤. 用于复杂非均相混合物体系的准确光谱定量分析方法，中国发明专利, 专利号：ZL9.6（2013.09.04）
陈增萍、李丽梅、金竞文. 一种粉末混合物的拉曼光谱准确定量分析方法，中国发明专利, 专利号：ZL5.1（2013.11.20）
陈增萍、金竞文、俞汝勤. 具有普适性的表面增强拉曼光谱定量分析技术，中国发明专利, 专利号：ZL4.0（2014.04.16）
陈增萍，陈瑶，田中群. 一种环境水体样本中镉离子含量的定量分析方法，专利号：ZL8.0（2016.06.08）
陈增萍，陈瑶，田中群. 一种增强SERS信号的方法及其应用，中国发明专利, 专利号：ZL1.5（2017.08.04）


奖励与荣誉
曾获湖南省2002自然科学技术一等奖