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湖南大学化学生物传感与计量学国家重点实验室导师教师师资介绍简介-何凤姣

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何凤姣,湖南大学化学化工学院教授,国务院政府特殊津贴专家,科技部创新创业人才,全国妇联执委,湖南省政协委员。发明了高耐磨性、高耐蚀性、环保型钨合金电镀技术,2011年获国家技术发明二等奖。该项目被列为2012年国家经信委推广的清洁生产工艺,已用于含有高硫化氢、二氧化碳、高矿化度的西南油气田和塔里木油田,获得好的效果。在微生物快速检测领域,主持研制开发了临床医疗急需的血培养仪,该仪器的研发,对我国提高诊疗水平,防止抗生素的滥用,具有重要意义。相关研究获2017年获湖南省自然科学一等奖。






基本信息
姓名:何凤姣
性别:
出生年月:1964年8月
职称:二级教授
最高学历及毕业时间:博士,1994年
工作单位:湖南大学化学化工学院,化学生物传感与计量学国家重点实验室
通讯地址:湖南大学化学化工学院
邮箱:fengjiaohe@hnu.edu.cn
手机:**
教育背景
1982.9-1986.7, 湖南大学化学化工学院, 分析化学本科
1986.9-1989.6, 湖南大学化学化工学院, 分析化学硕士
1991.9-1994.12,湖南大学化学化工学院, 分析化学博士

1997.1-1997.11 美国阿拉巴马大学医学院 博士后

1997.12-1998.12 美国加州大学洛杉矶分校 博士后




工作履历


1989.6-1991.8, 湘潭机电专科学校, 教师
1995.1-1996.12,湖南大学国际商学院,副教授

1999---至今,湖南大学化学化工学院, 教授



学术兼职
湖南省预防医学会卫生检验专业委员会副主任
湖南省环境保护厅特约环保监察员
研究领域
1.细菌、病毒传感器的研制与应用
利用压电传感原理,结合纳米技术、分子导线、表面修饰、叉指电极等,构建微生物快速检测系统,进行细菌、病毒的生长和代谢研究,开发出实用的检测方法和检测设备。
2.金属表面处理方法与应用研究
研究新的金属表面处理工艺及表面处理的废水零排放,废酸的回收循环利用,新型镀层表观形貌、结构的表征及相关性质的研究,侧重在制造领域表面处理及应用研究。
科研项目
1.国家自然科学基金仪器专项,**,压电生化传感仪,80万元
2.国家高技术研究发展计划(863计划),2013AA020203,基于荧光检测技术的自动化临床微生物检测分析仪器研制,80万
3.国家自然科学基金面上项目,**,基于核酸适配体的结核杆菌电化学传感器的研制与应用,80万
4.国家自然科学基金面上项目,**,分子导线压电微生物传感新技术理论与应用,26万元
5.国家自然科学基金面上项目,**,结核杆菌压电测试新技术研究与应用,36万元
6.国家科技支撑计划,有毒有害元素替代技术,85万元
7.钨合金表面处理工艺研究,湖南省重点计划,20万元


学术成果
授权专利
授权发明专利20项,授权实用新型专利3项。
成果转化
研制的血培养仪已获生产许可证和产品注册证书;
研制的电镀钨合金代镀铬,获得国家环保总局“环境保护A类推广证书”和“国家重点新产品”证书,被国家发改委评为260项实用环保技术之一,2008年列入无锡市政府530A类计划。
教材:无机化学,科学出版社,被评为国家十一五教材
发表论文:

[1]XiaoQing Zhang, Ye Feng, QiongQiong Yao, Fengjiao He*,Selection of a new Mycobacterium tuberculosis H37Rv aptamer and itsapplication in the construction of a SWCNT/aptamer/Au-IDE MSPQCH37Rv sensor,Biosensors and Bioelectronics,98 (2017) 261–26
[2]Xiaohong Shi, Xiaoqing Zhang, Qiongqiong Yao, Fengjiao He*,A novel method for the rapid detection of microbes in blood usingpleurocidin antimicrobial peptide functionalized piezoelectric sensor,Journal of Microbiological Methods 133 (2017) 69–75
[3]Fengjiao He*, Yunchang Xiong, Jing Liu, Feifei Tong, Danyang Yan,Construction of Au-IDE/CFP10-ESAT6 aptamer/DNA-AuNPs MSPQC forrapid detection of Mycobacterium tuberculosis,Biosensors and Bioelectronics 77 (2016) 799–804
[4]Yan Lian, Fengjiao He*, Huan Wang, Feifei Tong,A new aptamer/graphene interdigitated gold electrode piezoelectric
sensor for rapid and specific detection of Staphylococcus aureus,Biosensors and Bioelectronics 65 (2015) 314–319
[5]Feifei Tong, Yan Lian, Fengjiao He*,Novel S-MSPQC cell sensor for real time monitoring the injury of endothelial cell by LPS and assessing the drug effect on this injury,Biosensors and Bioelectronics 71 (2015) 62–67
[6]Fengjiao He*,Danyang Yan,Construction and Application of a NovelImpedance Sensor for Siderophore,Analytical Letters, 48:2, 259-268
[7]Feifei Tong, Yan Lian, Huang Zhou, Xiaohong Shi, and Fengjiao He*,Multichannel Series Piezoelectric Quartz Crystal Cell Sensor for RealTime and Quantitative Monitoring of the Living Cell and Assessmentof Cytotoxicity,Anal. Chem. 2014, 86, 10415-10421
[8]Yan Lian, Fengjiao He ?, Xianwen Mi, Feifei Tong, Xiaohong Shi,Lysozyme aptamer biosensor based on electron transfer fromSWCNTs to SPQC-IDE,Sensors and Actuators B 199 (2014) 377–383
[9]Xianwen Mi, Fengjiao He?, Meiyu Xiang, Yan Lian, Songlin Yi,Novel phage-piezoelectric sensor for rapid drug susceptibility testingof Mycobacterium tuberculosis,Sensors and Actuators B 193 (2014) 715–722
[10]Xiaohong Shi, Fengjiao He ?, Yan Lian, Danyang Yan, Xiaoqing Zhang,A new aptamer/SWNTs IDE-SPQC sensor for rapid and specificdetection of Group A Streptococcus,Sensors and Actuators B 198 (2014) 431–437
[11]F.J. He*, Y.Z. Fang, S.J. Jin,The study of corrosion–wear mechanism of Ni–W–P alloy,Wear 311 (2014) 14–20
[12]Xianwen Mi,Fengjiao He,*,Meiyu Xiang,Yan Lian,and Songlin Yi,Novel Phage Amplified Multichannel Series Piezoelectric QuartzCrystal Sensor for Rapid and Sensitive Detection of Mycobacteriumtuberculosis,Anal. Chem. 2012, 84, 939-946
[13]Fengjiao He*, Meiyu Xiang, and Xianwen Mi,A NEW BACTERIOPHAGE-MODIFIED PIEZOELECTRICSENSOR FOR RAPID AND SPECIFIC DETECTION OFMYCOBACTERIUM,Analytical Letters, 45: 1–12, 2012
[14]Fengjiao He,* Suzhen Chen and Lingling Zhang,The construction and application of a molecular wire piezoelectric
urease-producing bacteria sensor,Anal. Methods, 2012, 4, 2145
[15]Fengjiao He ?, Hui Su, Hui Ju, Ling Tan, Que Zhou,A new blackening process for NiWP alloy deposits,Surface & Coatings Technology 213 (2012) 133–138
[16]Fengjiao He, Li Lin, and Jiandang Zhou,Multi-Channel Series Piezoelectric Quartz Crystal Sensor with Partial Least Square Method for Identification ofClinically Relevant Bacteria,Sensor Lett. 9, 472-478 (2011)
[17]Ren J L, He F J, Zhang L L. The construction and application of a new PPY-MSPQC for l-asparaginase activity assay. Sensors and Actuators B: Chemical, 2010, 145:272-277
[18]He F J, Zhong M. New MSPQC-PLS method for the early clinic identification of commonly encountered Candida species. Talanta, 2010, 80 (3): 1210-1215
[19]He F J, Tu J R. New Medium for Rapid Quantification of Micrococcus Luteus Cells byMultic hannel Series Piezoelectric Quartz Crystal Based Method. Sensor letters, 2010, 8: 1-5
[20]He F J, Li T, Zhang L L, Yuan H, Zhou J D. New MSPQC Method for Rapid Identification and Quantification of Pseudomonas aeruginosa. Analytical Letters, 2009, 42(1): 58-67
[21]Su C W, Wang E L, Zhang Y B, He F J. Ni1?xFex (0.1 < x < 0.75) alloy foils prepared from a fluorborate bath using electrochemical deposition. Journal of Alloys and Compounds, 2009,474: 190-194
[22]Su C W, He F J, Ju H, Zhang Y B, Wang E L. Electrodeposition of Ni, Fe and Ni–Fe alloys on a 316 stainless steel surface in a fluorborate bath. Electrochimica Acta, 2009, 54: 6257-6263
[23]Ren J L, He F J, Yi S L, Cui X Y. A new MSPQC for rapid growth and detection of Mycobacterium tuberculosis. Biosensors and Bioelectronics, 2008, 24(3): 403-409
[24]He F J, Ren J L, Liu Z H. The study and application of a new IDE–PQC sensor. Sensors and Actuators B: Chemical, 2007, 123(2): 1057-1063
[25]Ren J L, He F J, Zhang L L, Su C W, Liu Z H. A new B-PAn-P system for the detection of bacteria population. Sensors and Actuators B: Chemical, 2007, 125: 510-516
[26]He F J, Zhou J. A new antimicrobial susceptibility testing method of Escherichia coli against ampicillin by MSPQC. Journal of Microbiology Methods, 2007, 68(3): 563-567
[27]He F J, Zhang X Q, Zhou J D, Liu Z H. A new MSPQC system for rapid detection of pathogens in clinical samples. Journal of Microbiology Methods, 2006, 66(1): 56-62
[28]He F J, Zhang X Q, Liu Z H. A new sensor method for studying the effect of surfactants on the growth of Pseudomonas aeruginosa. Sensors and Actuators B: Chemical, 2006, 113(1): 428-434




奖励与荣誉
2017年,湖南省自然科学一等奖
2016年,国务院特殊津贴
2013年,湖南省十大同心人物
2012,入选国家创新创业人才
2011年,国家科技发明一等奖

2009年获第四届中国技术市场协会金桥奖优秀项目奖;
2007年获中国机械工业科学技术一等奖,湖南省科技进步二等奖;






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