尹鹏

性 别：男

学历：博士

职称：教授

其他：博士生导师




*个人简历*
2018年12月 - 至今 湖南师范大学化学化工学院 教授
2012年8月 - 2018年12月 湖南师范大学化学化工学院 讲师
2007年8月 - 2012年4月 新加坡南洋理工大学 博士研究生 导师: Prof Loh Teck Peng
2006年7月 - 2007年7月 上海药明康德新药开发有限公司
2003年9月 - 2006年7月 中国协和医科大学 硕士研究生 导师: 王荣先 教授
1999年9月 - 2003年7月 吉林大学 本科
*研究方向*
荧光探针及其生物传感
*主持课题*
5) 同时区分Cys, Hcy和GSH的近红外荧光探针的构建及荧光定量研究（NO.**） 国家自然科学基金面上项目 2019年-2022年
4) 新型化学发光试剂及生物新材料的研究开发 2017年-2024年
3) 碱性磷酸酶检测体系的底物的开发 2016年-2019年
2) 检测β-内酰胺酶的荧光小分子探针的设计、合成及其在检测结核杆菌中的应用（NO.**） 国家自然科学基金青年基金 2015年-2017年
1) 新型阻燃剂的合成研究 2014年-2016年
*论文*
24) Guoxing Yin, Ting Yu,*Yabing Gan, Li Zhou*, Meiling Liu, Youyu Zhang, Ting Yu,* Haitao Li,Peng Yin* and Shouzhuo Yao, A novel fluorescent probe with dual-sites for simultaneously monitoring metabolisms of cysteine in living cells and zebrafishes, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2020, doi: 10.1016/j.saa.2020.118602.
23) Tingting Niu,^# Guoxing Yin,^# Ting Yu, Yabing Gan, Chenye Zhang, Juanjuan Chen, Wei Wu, Haimin Chen,* Haitao Li, Peng Yin,*A novel fluorescent probe for detection of Glutathione dynamics during ROS-induced redox imbalance. Anal. Chim. Acta, 2020, 1115, 52-60.
22) Yabing Gan,Guoxing Yin,Ting Yu,Youyu Zhang,Haitao Li, Peng Yin,* A novel fluorescent probe for selective imaging of cellular cysteine with large Stokes shift and high quantum yield. Talanta 2020, 210, 120612.
21) Guoxing Yin, Jingfeng Yao, Sai Hong, Yinuo Zhang, Zhaohua Xiao, Ting Yu,* Haitao Li and Peng Yin,* A Dual-responsive Colorimetric Probe for Detection of Cu²⁺ and Ni²⁺ Species in Real Water Samples and Human Serum, Analyst, 2019, 144, 6962-6967.
20) Guoxing Yin,^# Tingting Niu,^# Ting Yu,^# Yabing Gan, Xinyu Sun, Peng Yin,* Haimin Chen,* Youyu Zhang, Haitao Li* and Shouzhuo Yao,Simultaneous Visualization of Endogenous Homocysteine, Cysteine, Glutathione, and their Transformation through Different Fluorescence Channels, Angew. Chem. Int. Ed., 2019, 58, 4557-4561.
19) Tingting Niu,^# Ting Yu,^# Guoxing Yin, Haimin Chen,* Peng Yin* and Haitao Li. A novel colorimetric and ratiometric fluorescent probe for sensing SO₂ derivatives and their bio-imaging in living cells. Analyst, 2019,144, 1546-1554
18) Zile Zhou, Yaqian Li, Wei Su, Biao Gu, Hai Xu, Cuiyan Wu,Peng Yin, Haitao Li* and Youyu Zhang. A dual-signal colorimetric and near-infrared fluorescence probe for the detection of exogenous and endogenous hydrogen peroxide in living cells. Sens. Actuators, B, 2019, 280, 120-128.
17) Cuiyan Wu, Xiaojun Hu, Biao Gu,Peng Yin, Wei Su, Yaqian Li, Qiujun Lu, Youyu Zhang and Haitao Li,* A lysosome-targeting colorimetric and fluorescent dual signal probe for sensitive detection and bioimaging of hydrogen sulfide. Anal. Methods, 2018, 10, 604-610.
16) Guoxing Yin, Yabing Gan, Ting Yu, Tingting Niu, Peng Yin,* Haimin Chen, Youyu Zhang, Haitao Li and Shouzhuo Yao, A dual-emission and mitochondria-targeted fluorescent probe for rapid detection of SO₂ derivatives and its imaging in living cells, Talanta, 2019, 191, 428-434.
15) Guoxing Yin, Tingting Niu, Yabing Gan, Ting Yu,Peng Yin,* Haimin Chen,* Youyu Zhang, Haitao Li* and Shouzhuo Yao, A Multi-signal Fluorescent Probe with Multiple Binding Sites for Simultaneous Sensing of Cysteine, Homocysteine and Glutathione. Angew. Chem. Int. Ed., 2018, 57, 4991-4994
14) Ting Yu, Guoxing Yin,Tingting Niu, Peng Yin*, Haitao Li*, Youyu Zhang, Haimin Chen*, Ying Zeng and Shouzhuo Yao, A novel colorimetric and fluorescent probe for simultaneous detection of SO₃^2-/HSO₃^- and HSO₄^- by different emission channels and its bioimaging in living cells. Talanta, 2018, 176, 1–7.
13) Hai Xu, Biao Gu, Yaqian Li, Zhen Huang, Wei Su, Xiaoli Duan,Peng Yin,* Haitao Li* and Shouzhuo Yao, A highly selective, colorimetric and ratiometric fluorescent probe for NH₂NH₂ and its bioimaging. Talanta, 2018, 180, 199-205.
12) Guoxing Yin, Ting Yu, Tingting Niu,Peng Yin,* Haimin Chen, Youyu Zhang, Haitao Li* and Shouzhuo Yao, A novel fluorescence turn-on probe for the selective detection of thiophenols by caged benzooxazolidinoindocyanine. RSC Adv., 2017, 7 46148-46154.
11) Ting Yu, Guoxing Yin,Peng Yin, *Ying Zeng, Haitao Li,* Youyu Zhang and Shouzhuo Yao, A novel long-wavelength fluorescent probe for discrimination of different palladium species based on Pd-catalyzed reactions. RSC Adv., 2017, 7, 24822–24827.
10) Xiaojun Hu, Wei Su, Qiulan Zhou,Peng Yin, Haitao Li* and Shouzhuo Yao. An excited-state intramolecular proton transfer-based probe for the discrimination of thiophenols over aliphatic thiols. Anal. Methods, 2016, 8 1425-1430.
9) Qiujun Lu, Jiangna Zhao, Shanyan Xue,Peng Yin, Youyu Zhang* and Shouzhuo Yao. A "turn-on" fluorescent sensor for ultrasensitive detection of melamine based on a new fluorescence probe and AuNPs. Analyst , 2015, 140 1155-1160.
8) Hai-Xiao Jin, Mei-Lin Go,Peng Yin, Xiao-Ting Qiu, Peng Zhu and Xiao-Jun Yan,* Determining the Functions of HIV-1 Tat and a Second Magnesium Ion in the CDK9/Cyclin T1 Complex: A Molecular Dynamics Simulation Study. PLoS One, 2015, 10 e**.
7) Liyan Huang, Biao Gu, Wei Su,Yin Peng and Haitao Li,* Proton donor modulating ESIPT-based fluorescent probes for highly sensitive and selective detection of Cu²⁺. RSC Adv., 2015, 5 76296-76301.
6) Biao Gu, Naxiu Mi, Youyu Zhang,Peng Yin, Haitao Li* and Shouzhuo Yao. A tetraphenylimidazole-based fluorescent probe for the detection of hydrogen sulfide and its application in living cells. Anal. Chim. Acta, 2015, 879 85-90.
5) Biao Gu, Liyan Huang, Naxiu Mi,Peng Yin, Youyu Zhang,* Xinman Tu, Xubiao Luo, Shenlian Luo and Shouzhuo Yao. An ESIPT-based fluorescent probe for highly selective and ratiometric detection of mercury(II) in solution and in cells. Analyst, 2015, 140 2778-2784.
4) Peng Yin, Mun Yee Wong, Jieying Tham,and Teck-Peng Loh, * Palladium-catalyzed amination of allylic carbonates with ammonia: access to primary amines. Org. Chem. Front., 2014, 1, 1266-1269(cover paper)
3) Chang Liu, Youming Shen,Peng Yin, Lidong Li, Meiling Liu, Youyu Zhang, Haitao Li* and Shouzhuo Yao. Sensitive detection of acetylcholine based on a novel boronate intramolecular charge transfer fluorescence probe. Anal. Biochem., 2014, 465 172-178.
2) Mingjie Wei ,Peng Yin, Youming Shen, Lingli Zhang, Jianhui Deng, Shanyan Xue, Haitao Li, Bin Guo, Youyu Zhang * and Shouzhuo Yao, A new turn-on fluorescent probe for selective detection of glutathione and cysteine in living cells. Chem. Commun., 2013, 49,4640-4642.
1) Peng Yin and Teck-Peng Loh, * Intermolecular Hydroamination between Nonactivated Alkenes and Aniline Catalyzed by Lanthanide Salts in Ionic Solvents. Org. Lett., 2009, 17, 3791-3793.
*专利*
授权专利
1) 尹鹏; 喻婷; 尹国兴; 李海涛; 一种新型检测苯硫酚荧光分子探针的制备方法和应用。CNB
2) 尹鹏 ;尹国兴 ;喻婷 ;李海涛 ;一种线粒体靶向pH比率型荧光探针的制备方法和应用。CNB
申请专利
10) 尹鹏 ;徐晨露；甘亚兵;喻婷 ;尹国兴 ;张友玉 ;一种Nitro-PAPS的合成方法。CNA
9)尹鹏;喻婷;尹国兴;一种同时区分检测Cys、Hcy和GSH多功能荧光分子探针的合成及应用。CNA
8) 尹鹏 ;尹国兴 ; 甘亚兵;喻婷 ;孙鑫雨; 张友玉 ;多信号荧光探针的合成及其同时区分检测Hcy、Cys和GSH的应用。CNA
7) 尹鹏 ;尹国兴 ; 喻婷 ;甘亚兵;徐晨露;李海涛;一种比色法检测水中Cu和Ni探针的合成与应用。CNA
6) 尹鹏 ;喻婷 ;尹国兴 ;李海涛 ;张友玉 ;一种荧光增强型快速检测亚硫酸氢根离子或亚硫酸根离子荧光分子探针的合成和应用。CNA
5) 尹鹏 ;尹国兴 ;喻婷 ;李海涛 ;一种线粒体靶向pH比率型荧光探针的制备方法和应用。CNA
4) 尹鹏 ;喻婷 ;尹国兴 ;李海涛 ;徐晨露 ;一种新型检测H₂S荧光分子探针的制备方法和应用。CNA
3) 尹鹏 ;尹国兴 ;喻婷 ;曾盈 ;李海涛 ;一种比色和比率型检测SO₂及其衍生物荧光探针的合成和应用。CNA
2) 尹鹏 ;尹国兴 ;李海涛 ;喻婷 ;曾盈 ;张友玉 ;一种比率型检测HSO₄离子和SO₂及其衍生物的双功能荧光分子探针。CNA
1) 尹鹏 ;谢朝龙 ;夏开富 ;尹国兴 ;喻婷 ;吖啶酯类化学发光底物DMAE·NHS的合成。CNA
*学术职务*
Chinese Chemical Letters 青年编委
*联系方式*
yinpeng@hunnu.edu.cn