导师简介
| 姓名 | 于阿娟 | 性别 | 女 | 出生年月 | 1978年4月 | 照片 | |
| 职称 | 副教授 | 民族 | 汉 | 籍 贯 | 河南洛阳 | ||
| 电子邮箱 | yuajuan@zzu.edu.cn | 最终学位 | 博士 | ||||
| 学术头衔/兼职 | 无 | ||||||
| 研究方向 | 手性分离介质的合成、应用及手性识别机理研究 | ||||||
| 主要学习、科研和工作经历 | 1997年9月-2001年6月，郑州大学化学系，获应用化学专业理学学士学位； 2001年9月-2004年6月，郑州大学化学系，获分析化学专业理学硕士学位； 2006年9月-2009年6月，郑州大学化学系，获有机化学专业理学博士学位； 2012年1月-2014年12月，郑州大学药学院，博士后； 2019年3月-2020年3月，香港浸会大学，访问学者。 | ||||||
| 代表性 教学成果与荣誉 | 多次评为网上教评优秀教师； 指导2019年度郑州大学大学生创新创业训练计划项目一项。 | ||||||
| 代表性 科研成果 | 一、主持的项目： 1、 国家自然科学基金面上项目，**、基于MOF-磁性石墨烯功能材料富集和分离手性药物的研究、2017/01-2020/12、直接经费65万、在研、主持。 2、 中国烟草总公司科技发展基金（横向项目），不同产地、部位烟梗和烟叶中细胞壁成分的差异规律研究、2016/04-2016/07、69万、已结题、主持。 3、 国家自然科学基金青年基金项目，**、基于Fc 分子骨架的新型功能化固定相的设计制备、色谱性能及保留机制研究、2013/01-2015/12、25万元、已结题、主持。 4、 博士后面上资助项目，2012M511592、新型功能化Fc固定相的合成及其对药物分子的手性拆分、2012/01-2013/12、5万元、已结题、主持。 5、 中国烟草总公司科技发展基金（横向项目），烟草、卷烟烟气中有害成分的毛细管电泳分析技术应用研究、2010/01-2011/12、15万元、已结题、主持。 6、 黄河水利委员会科研基金（横向项目），黄河重点城市水源地典型有毒有机物筛选及供水安全性评价、2008/01-2010/12、9.6万元、已结题、主持。 二、论文论著 [1] Xue Ma, Yanhao Zhang, Yu Gao, Xinglin Li, Cuijie Wang, Hang Yuan, Ajuan Yu*, Shusheng Zhang, Yuanyuan Cui. Reveal of the chiral recognition for alanine and leucine in an L-phenylalanine-based metal-organic framework. Chemical Communications, 2020, 56, 1034-1037. [2] Xinglin Li, Yu Gao, Cuijie Wang, Jiting Cui, Ajuan Yu*, Shusheng Zhang. Facile synthesis of 3D flower-like SiO2-MOF architecture with copper oxide as copper source for enantioselective capture. New Journal of Chemistry, 2019, 43, 16123-16126. [3] Xue Ma, Wenrui Du, Chenfeng Hua, Yan Li, Ajuan Yu*, Wuduo Zhao, Shusheng Zhang, Fuwei Xie. Facile preparation of optically pure PROs using novel MOFs functionalized composites and in vitro study of growth inhibitory and apoptosis effects on non-small cell lung cancer. Journal of Pharmaceutical and Biomedical Analysis, 2019, 172, 50-57. [4] Yu Gao, Wenrui Du, Ajuan Yu*, Xinglin Li, Wuduo Zhao, Shusheng Zhang. Engineering MOF-magnetic graphene nanocomposite for enantioselective capture of chiral drug intermediates. Analytical Methods, 2018, 10, 5811-5816. [5] Xue Ma, Xiaohua Zhou, Ajuan Yu*, Wuduo Zhao, Wenfen Zhang, Shusheng Zhang*, Linlin Wei, Debra J. Cook, Anirban Roy. Functionalized MOF nanocomposites for dispersive solid phase extraction and enantioselective capture of chiral drug intermediates. J. Chromatogr. A, 2018, 1537, 1-9. [6] Lijun Qiao, Xiaohua Zhou, Xue Li, Wenrui Du, Ajuan Yu*, Shusheng Zhang, Yangjie Wu. Synthesis and performance of chiral ferrocene modified silica gel for mixed-mode chromatography. Talanta, 2017, 163, 94-101. [7] Wenfen Zhang, Yanhao Zhang, Qiong Jiang, Wenjie Zhao*, Ajuan Yu, Hong Chang, Ximei Lu, Fuwei Xie, Baoxian Ye and Shusheng Zhang*. Tetraazacalix[2]arence[2]triazine Coated Fe3O4/SiO2 magnetic nanoparticles for simultaneous dispersive solid phase extraction and determination of trace multitarget analytes. Analytical Chemistry, 2016, 88, 10523-10532. [8] Lijun Qiao, Xiaohua Zhou, Yanhao Zhang, Ajuan Yu*, Kai Hu, Shusheng Zhang, Yangjie Wu. 4-Chloro-6-pyrimidinylferrocene modified silica gel: a novel multiple-function stationary phase for mixed-mode chromatography. Talanta, 2016, 153, 8-16. [9] Lijun Qiao, Xiaohua Zhou, Yanhao Zhang, Ajuan Yu*, Shusheng Zhang*, Yangjie Wu. Determination of Trace sulfonamides in foodstuffs by High Performance Liquid Chromatography Using a Novel Mixed-Mode Functionalized ferrocene Sorbent for Solid-Phase Extraction Cleanup. Analytical Methods, 2016, 8, 6099-6106. [10] Yanhao Zhang, Liu Yang, Xiangyu Tian, Yaxiao Guo, Wei Tang, Ajuan Yu*, Wenfen Zhang, Baoguo Sun, Shusheng Zhang*. Determination of Trace Nitrites and Nitrates in Human Urine and Plasma by Field-amplified Sample Stacking Open-tubular Capillary Electrochromatography in a Nano-latex Coated Capillary. Journal of Analytical Chemistry, 2015, 70(7), 885-891. [14] Xiaohua Zhou, Xiaole Li, Aijuan Cao, Lijun Qiao, Ajuan Yu*, Shusheng Zhang*, Yangjie Wu. Development of N-ferrocenyl(benzoyl)amino-acid esters stationary phase for high performance liquid chromatography. Talanta, 2015, 144, 1044-1051. [11] Heng Tian, Aijuan Cao, Lijun Qiao, Ajuan Yu*, Junbiao Chang and Yangjie Wu*. First palladium-catalyzed denitrated coupling of nitroarenes with Sulfinates. Tetrahedron, 2014, 70(47), 9107-9112. [12] Hailei Wang, Yuping Ma, Heng Tian, Ajuan Yu*, Junbiao Chang, Yangjie Wu*. Tetrabutylammonium Bromide-Mediated Benzylation of Phenols in Water under Mild Condition. Tetrahedron, 2014, 70(16), 2669-2673. [13] Yanhao Zhang, Xiangyu Tian, Yaxiao Guo, Haibin Li, Ajuan Yu*, Zhifen Deng, Barry Baoguo Sun, Shusheng Zhang*. Analysis of Nitrites and Nitrates in Hams and Sausages by Open-Tubular Capillary Electrochromatography with a Nanolatex-Coated Capillary Column. J. Agric. Food Chem., 2014, 62, 3400-3404. [14] Ajuan Yu, Dongpo Peng, Kai Hu, Aijuan Cao, Junbiao Chang*, Yangjie Wu, Shusheng Zhang*. A new 4-ferrocenylbenzoyl chloride-bonded stationary phase for high performance liquid chromatography. J. Chromatogr. A, 2013, 1283, 75-81. [15] Dongpo Peng, Ajuan Yu*, Hailei Wang, Yangjie Wu*, Junbiao Chang*. A 2,2’-bipyridine-palladacycle catalyzed the coupling of arylboronic acids with nitroarenes. Tetrahedron, 2013, 69(33), 6884-6889. [16] Hailei Wang, Ajuan Yu*, Aijuan Cao, Junbiao Chang, Yangjie Wu*. First Palladium-Catalyzed Denitrated Coupling Reaction of Nitroarenes with Phenols. Appl. Organomet. Chem., 2013, 27(10), 611-614. [17] Kai Hu, Junwei Liu, Chao Tang, Caijuan Wang, Ajuan Yu*, Fuyong Wen, Wenjie Zhao, Baoxian Ye, Yangjie Wu, Shusheng Zhang. Preparation, characterization and application of a new 25, 27-bis-[2-(5-methylthiadiazole)thioethoxyl]-26, 28-dihydroxy-para-tert-butyl calix[4]arene stationary phase for HPLC. J. Sep. Sci., 2012, 35(2), 239-247. [18] Ajuan Yu, Lei Shen, Xiuling Cui, Dongpo Peng, Yangjie Wu*. Palladacycle-catalyzed cross-coupling reactions of arylboronic acids with carboxylic anhydrides or acyl chlorides. Tetrahedron, 2012, 68(10), 2283-2288. [19] Ajuan Yu, Xiangdong Li, Dongpo Peng, Yangjie Wu*, Junbiao Chang*. Cyclopalladated ferrocenylimine as efficient catalyst for the syntheses of diarylmethane derivatives. Appl. Organomet. Chem., 2012, 26(6), 301-304. [20] Ajuan Yu, Yangjie Wu, Baoli Cheng, Kun, Wei, Jingya Li. A Mild, one-Pot synthesis of arylamines via Pd-catalyzed addition of arylaldehydes with amines and arylboronic acids in water. Adv. Synth. Catal., 2009, 351(5), 767-771. [21] Ajuan Yu, Baoli Cheng, Yangjie Wu, Jingya Li, Kun, Wei. Cyclopalladated complexes catalyzed addition of arylboronic acids to aldehydes in neat water. Tetrahedron Lett., 2008, 49(37), 5405-5407. [22] Ajuan Yu, Jingya Li, Mengjun Cui, Yangjie Wu. Addition of arylboronic acids to nitriles in aqueous media catalyzed by a 2,2'-bipyridine-cyclopalladated ferrocenylimine complex. Synlett, 2007, (19), 3063-3067. 三、专利 [1] 于阿娟, 高煜, 马雪, 张书胜. 一种手性MOFs功能材料及其制备方法和用途. 国家发明专利, 申请号: **2670.5. [2] 于阿娟, 杜文瑞, 李艳, 张书胜, 赵无垛, 陈胜. 一种MOF-磁性石墨烯杂化材料及其在手性拆分和体外细胞毒性方面的应用. 国家发明专利, 申请号: **7849.7. [3] 于阿娟, 周晓华, 杜文瑞, 高煜, 张书胜. 手性MOF-磁性石墨烯功能材料及其制备方法和用途. 国家发明专利, 申请号: **5658.4; 公开号: CN**3B; 专利号: ZL**5658.4. 授权日期: 2018. 11. 13. [4] 于阿娟, 曹爱娟, 王海磊, 赵文杰, 蒋琼, 张书胜. N-二茂铁基（苯酰基）-苯丙氨酸甲酯键合硅胶固定相及其制备方法和应用. 国家发明专利, 申请号: **1645.3; 公开号: CN**0A; 专利号: ZL**1645.3. 授权日期: 2015. 09. 30. [5] 于阿娟, 乔丽君, 周晓华, 曹爱娟, 赵文杰, 张书胜, 吴养洁. 一种固相萃取填料及其在测定食品中磺胺残留的应用. 国家发明专利, 申请号: **7489.6.
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