姓名

于明明

性别

男

出生年月

1975年7月

职称

教授

民族

汉族

籍 贯

黑龙江

电子邮箱

yumm@zzu.edu.cn

最终学位

博士

学术头衔/兼职

《中国化学快报》青年编委

研究方向

生物荧光分子探针/功能高分子

主要学习、科研和工作经历

2005.7-2007.06，清华大学化学系，博士后；

2007.9-2011.4，郑州大学化学系，教师；

2011.4-2019.12，郑州大学化学学院，副教授；

2011.9，校级青年骨干教师；

2012.9，省级青年骨干教师；

2016.1-2019.12，郑州大学化学学院，直聘教授；

2017.8-2018.8，美国新泽西理工学院，访问学者。

2019.12至今，郑州大学化学学院，教授

代表性

教学成果与荣誉

作为2014级化学8班班主任2015年和2016年两次被评为郑州大学优秀班主任；指导的本科生毕业论文得院优秀毕业论文（杨帆）；2017年作为指导教师获省级大学生实验创新项目优秀奖。

指导的研究生多次获得国家奖学金，袁瑞丽和周婉获得2013年度国家奖学金，刘春霞获得2015年度国家奖学金，杜玮玮获得2016年度国家奖学金。2017年指导的研究生杜玮玮获省级优秀毕业论文。2015年周婉同学获得校级优秀毕业论文和省级优秀研究生。

代表性

科研成果

一、科研项目

国家自然科学基金“羧酸酯酶的上转换复合纳米近红外比率发光探针的制备及其生物成像”（项目批准号：U**）

郑州大学化学与分子工程学院“青年学术骨干”教师基金

国家自然科学基金“具有双识别协同作用的锌、铜离子荧光分子探针”（项目批准号：**）

中国科学院光化学转换与功能材料重点实验室开放课题“人造捕光天线的分子设计与应用”

横向课题“新型显色离子吸附剂的研制”

二、论文论著

1. Hou, Y.; Liu, H.X.; Li, Z.X.*; Zhang, H.Y.*; Wei, L.H.; Yu, M.M.* One-step synthesis of mitochondrion-targeted fluorescent carbon dots and fluorescence detection of silver ions. Anal. Methods, published online.

2. Bu, D.D.; Song, H.H.; Li, Z.X.*; Wei, L.H.; Zhang, H.Y.*; Yu, M.M.* Carbon-dot-based ratiometric fluorescent probe of intracellular zinc ion and persulfate ion with low dark toxicity. Luminescence, published online.

3. Liu, W.J.; Wang, Y.Y.; Wu, N.; Feng, W.; Li, Z.X.*; Wei, L.H.; Yu, M.M.* A mitochondrion-targeting fluorescent probe for hypochlorite anion in living cells. Spectrochim. Acta A, 2020, 240, 118564.

4. Li, Y.Y.; Ban, Y.N.; Wang, R.H.; Wang, Z.; Li, Z.X.*; Fang, C.J.; Yu, M.M.* FRET-based Ratiometric Fluorescent Detection of Arginine in Mitochondrion with a Hybrid Nanoprobe. Chin. Chem. Lett., 2020, 31, 443–446.

5. Hu,J.; Huang, S.; Yu, M.M.; Yu H.F.* Flexible Solar Thermal Fuel Devices: Composites of Fabric and a Photoliquefiable Azobenzene Derivative, Adv. Energy Mater. 2019, **–**.

6. Wang, Y.Y.; Liu, H.X.; Song, H.H.; Yu, M.M.*; Wei, L.H.; Li, Z.X.* Synthesis of dual-emission fluorescent carbon quantum dots and their ratiometric fluorescence detection for arginine in 100% water solution. New J. Chem., 2019, 43, 13234–13239.

7. Li, Z.X.; Liu, H.X.; Li, H.X.; Tsou, Y.H.; Gao, Y.L.; Xu*, X.Y.; Du, W.W.; Wei, L.H.; Yu, M.M.* Lysosome-targeting NIR Ratiometric Luminecent Upcoversion Nanoprobe toward Arginine. Sens. Actuators B, 2019, 280, 94–101.

8. Song, H.H.; Du, W.W.; Liu, C.X.; Li, Z.X.*; Zhang, H.Y.*; Wei, L.H.; Yu, M.M.* Self-Assembled Micellar Nanosensor toward pH with high photo-stability and its application in living cells. Sens. Actuators B, 2018, 273, 927–934.

9. Ban, Y.; Wang, R.H.; Li, Y.; An, Z.; Yu, M.M.*; Fang, C.J.*; Wei, L.; Li, Z.X. Mitochondria-targeted ratiometric fluorescent detection of hydrazine with fast response time. New J. Chem., 2018, 42, 2030−2035.

10. Shi, B. J.; He,Y. Y.; Zhang, P. P.; Wang, Y. L.; Yu, M. M.*; Zhang, H. Y.*; Wei, L. H.; Li, Z. X.* Turn on fluorescent detection of hydrazine with a 1,8-naphthalimde derivative. Dyes Pigments, 2017, 147, 152–159.

11. He,Y. Y.; Li, Z. X.*; Jia, Q. Y.; Shi, B. J.; Zhang, H. Y.*; Wei, L. H.; Yu, M. M.* Ratiometric fluorescent detection of acidic pH in lysosome with carbon nanodots. Chin. Chem. Lett., 2017, 28(10), 1969-1974.

12. Li, H. X; Dong, H.; Yu, M. M.; Liu, C. X.; Li, Z. X.; Wei, L. H.; Sun, L. D.; Zhang, H. Y. NIR ratiometric luminescence detection of pH fluctuation in living cells with hemicyanine derivative-assembled upconversion nanophosphors. Anal. Chem., 2017, 89, 8863−8869.

13. Shi, B. J.; Qi, S. J.; Yu, M. M.; Liu, C. X.; Li, Z. X.; Wei, L. H.; Ni, Z. H. Colorimetric and fluorescent detection of hydrazine with high sensitivity and excellent selectivity. Spectrochim. Acta A, 2018, 188, 208–212.

14. He,Y. Y.; Li, Z. X.; Shi, B. J.; An, Z.; Yu, M. M.; Wei, L. H.; Ni, Z. H. A new near-infrared ratiometric fluorescent probe for hydrazine. RSC Adv., 2017, 7, 25634–25639.

15. Yu, M. M.*; Du, W. W.; Li, H. X.; Zhang, H. Y.*; Li, Z. X.* Near-infrared ratiometric fluorescent detection of arginine in lysosome with a new hemicyanine derivative. Biosens. Bioelectron., 2017, 92, 385–389.

16. An, Z.; Li, Z. X.*; He, Y.; Shi, B.; Wei, L.; Yu, M. M.* Ratiometric luminescent detection of hydrazine with a carbon dots-hemicyanine nanohybrid system. RSC Adv., 2017, 7, 10875–10880.

17. Li, Z. X.;* Zhang, W. Y.; Liu, C. X.; Yu, M. M.*; Zhang, H. Y.*; Guo, L.; Wei, L. H. A colorimetric and ratiometric fluorescent probe for hydrazine and its application in living cells with low dark toxicity. Sens. Actuators B, 2017, 241, 665–671.

18. Shi, B. J.; Gao, Y. L.; Liu, C. X.; Feng, W. Li, Z. X.; Wei, L. H.; Yu, M. M.* A ratiometric fluorescent sensor for pH fluctuation and its application in living cells with low dark toxicity. Dyes Pigments, 2017, 136, 522–528.

19. Li, Z. X.; Li, H. X.; Shi, C. X.; Yu, M. M.; Wei, L. H.; Ni Z. H. Nanomolar colorimetric quantitative detection of Fe³⁺ and PPi with high selectivity. Spectrochim. Acta A, 2016, 159, 249–253.

20. Yu, M. M.*, Du, W. W.; Zhou, W.; Li, H. X.; Liu, C. X.; Wei, L. H.; Li, Z. X.*; Zhang, H. Y. A 1,8-naphthalimide-based chemosensor with an off-on fluorescence and lifetime imaging response for intracellular Cr³⁺ and further for S²⁻. Dyes Pigments, 2016, 126, 279–285.

21. Li, Z. X.*; Li, H. X.; Shi, C. X.; Zhang, W. Y.; Zhou, W.; Wei, L. H.; Yu, M. M.* Naked-eye-based highly selective sensing of Fe³⁺ and further for PPi with nano copolymer Film. Sens. Actuators B, 2016, 226, 127–134.

22. Yu, M. M.*; Xu, J.; Peng, C.; Li, Z. X.; Liu, C. X.; Wei, L. H. A novel colorimetric and fluorescent probe for detecting fluoride anions: from water and toothpaste samples. Tetrahedron, 2016, 72, 273–278.

23. Xu, L. J.; Liang, X. Y.; Zhang, L.; Wu, J. B.; Li, Z. X.; Yu, M. M.*; Wei, L. H.* The vesicle formation of β-CD and AD self-assembly of dumbbell-shaped amphiphilic triblock copolymer. Colloid Polym. Sci., 2016, 294, 145–155.

24. Zhang, W. Y.; Liu, X. J.; Zhang, H. Y.; Feng, C. C.; Liu, C. X.; Yu, M. M.*; Wei, L. H.; Li, Z. X.* A fluorescent probe for benzenethiols and its application on test paper, in water samples and living cells. J. Mater. Chem. C, 2015, 3, 8248–8254.

25. Liu, C. X.; Shi, C. X.; Li, H. X.; Du, W. W.; Li, Z. X.*; Wei, L. H.; Yu, M. M.* Nanomolar fluorescent quantitative detection of formaldehyde with a 8-hydroxyquinoline derivative in aqueous solution and electrospun nanofibers. Sens. Actuators B, 2015, 219, 185–191.

26. Li, Z. X.*; Zhang, W. Y.; Liu, X. J.; Liu, C. X.; Yu, M. M.*; Wei, L. H.* Naked-eye-based selective detection of pyrophosphate with Zn²⁺ complex in aqueous solution and electrospun nanofibers. RSC Adv., 2015, 5, 25229–25235.

27. Liu, C. X.; Xu, J.; Yang, F.; Zhou, W.; Li, Z. X.*; Wei, L. H.; Yu, M. M.* Nanomolar Cu²⁺ and F^– naked-eye detection with a 1,8-naphthalimide-based colorimetric probe. Sens. Actuators B, 2015, 212, 364–370.

28. Du, W. W.; Xu, J.; Li, H. X.; Feng, C. C.; Yu, M. M.*; Li Z. X.;* Wei L. H. Naked-eye and fluorescent detection of basic pH and F⁻ with a 1,8-naphthalimide-based multifunctional probe. RSC Adv., 2015, 5, 15077–15083.

29. Zhou, W.; Dong, H.; Yan, H.; Shi, C. X.; Yu, M. M.*; Wei, L. H.; Li, Z. X.* HCHO-reactive molecule with dual-emission-enhancement property for quantitatively detecting HCHO in near 100% water solution. Sens. Actuators B, 2015, 209, 664–669.

30. Liu, X. J.; Zhang, W.Y.; Li, C. X.; Zhou, W.; Li, Z. X.*; Yu, M. M.*; Wei, L. H. Nanomolar detection of Hcy, GSH and Cys in aqueous solution, test paper and living cells. RSC Adv., 2015, 5, 4941–4946.

三、授权专利

· 于明明、李占先、杜玮玮、李海霞、魏柳荷，一种溶酶体定位荧光探针、制备方法及在近红外比率检测精氨酸中的应用。2019.02.26，中国，专利号：ZL**3191.8

· 于明明、施冰杰、刘春霞、李占先、魏柳荷，一种线粒体靶向的pH敏感的比率型荧光探针及其制备方法和应用。2018.01.05，中国，专利号：ZL**1971.8

· 于明明、张文英、李占先、石彩霞、周婉、魏柳荷，一种高分子比色纳米薄膜材料及其制备方法以及用于Fe³⁺和焦磷酸根检测方面的应用。2018.08.14，中国，专利号：ZL**2665.9

· 于明明、李海霞、严晗、周婉、李占先、魏柳荷，一种甲醛快速检测试剂及其制备方法与应用。2016.11.02，中国，专利号：ZL**0026.2

· 于明明、张文英、刘兴江、周婉、李占先、魏柳荷，一种检测焦磷酸根的纳米纤维膜试条、制备方法及其应用。2015.12，中国，专利号：ZL**2826.0

· 于明明、李占先、魏柳荷、刘兴江，一种氟硼荧光衍生物、其制备方法及应用。2015.12，中国，专利号：ZL**1197.0

· 于明明、乔钰茜、李占先、魏柳荷、郭永开，2,4-二苯基-5,6-二吡啶基-苯酚及其制备。2015.07，中国，专利号：ZL**8992.2

· 于明明、李占先、魏柳荷、张利锋、赵万莹、王丽娜，苯衍生物金属离子荧光探针及其应用。2014.4，中国，专利号：ZL**9893.9