牛玉娜，1982.01-，中山大学动物学博士学位。目前研究方向为分子免疫学，主要从事成人T淋巴细胞白血病病毒1型感染HTLV-1致白血病ATL机制研究、以及NK细胞活性调控分子机制研究。主持国家自然科学基金青年项目1项，河南省自然科学基金1项；在Carcinogenesis、Immunology等杂志上发表论文17篇。
主持的科研项目：
1. 河南省自然科学基金，EVI1通过调控自噬参与白血病干细胞的干性维持，2016-2018,10万元，项目编号**3，主持人
2. 国家自然科学基金，BCL3通过STAT3调控NK细胞的功能和机制研究，2018/1/1-2020/12/30，20万元，项目编号**，主持人
发表SCI论文一览表（#为第一作者，*为通讯作者）
1. Yuna Niu#,Xue Yang, Yifei Chen, Xinyue Jin, Li Li, Yilin Guo, Xuelu Li,Yecheng Xie,Yun Zhang, Hui Wang.EVI1induces autophagyto promote drug resistance via regulation of ATG7expression in leukemia cells.Carcinogenesis. 2019 (accepted)
2. Yuna Niu#, Xue Yang, Yifei Chen, Linbo Zhang, Xinyue Jin, Youjing Tang, Li Li, Lu Yu,Yilin Guo, Hui Wang.BCL3 expressionis apotentialprognostic andpredictivebiomarker inacutemyeloidleukemia of FAB Subtype M2. Pathol Oncol Res. 2019 Apr;25(2):541-548. doi: 10.1007/s12253-018-0476-7.
3. Yuna Niu#, Xue Yang, Yifei Chen, Xinyue Jin, Yecheng Xie,Youjing Tang,Li Li, Shibo Liu,Yilin Guo,Xuelu Li,Liangwei Duan,Hui Wang.Distinct prognostic values of Annexin family members expression in acute myeloid leukemia.Clin Transl Oncol. 2019 Jan 29. [Epub ahead of print]
4. Yuna Niu#,Qingqing Liu,SupingZhang,NaYuan,YanCao,JinyangCai,Weiwei Lin,FeiXu,ZhenWang,JianrongWang. Alternative messenger RNA splicing of autophagic gene Beclin 1 in human B-cell acute lymphoblastic leukemia cells. Asian Pac J Cancer Prev. 2014;15(5):2153-8.
5. Yuna Niu#, Delin Mo, Limei Qin, Chong Wang, Anning Li, Xiao Zhao, Xiaoying Wang, Shuqi Xiao, Qiwei Wang, Ying Xie, Zuyong He, Peiqing Cong, Yaosheng Chen*. Lipopolysaccharide-induced miR-1224 negatively regulates tumour necrosis factor-α gene expression by modulating Sp1. Immunology. May;133(1):8-20. doi: 10.1111/j.1365-2567.2010.03374.x. Epub Feb 14. 2011
6. 李莉,张艺博,张林波,汤友静,陈逸飞,关丫丫,牛玉娜*. BCL3基因敲除对线粒体呼吸作用及ATP合成的影响.中国细胞生物学学报, 2018, 40(4): 533-541
7. 张林波,牛玉娜,王辉.信号转导与转录激活因子和肿瘤微环境对自然杀伤细胞功能及免疫监视影响的研究进展.新乡医学院学报,2017, 34(11), 1037-1039
8. 汤友静,牛玉娜,王辉. Pink1/Parkin介导的线粒体自噬分子机制.中国细胞生物学学报,2017, 39(7), 939-946
9. Yun Zhang, Wenqing Tan, Lin Zhang, Shuyou Shi,Yuna Niu, Xue Yang, Jinjuan Qiao, Hui Wang. Highly sensitive and selective colorimetricdetermination of Staphylococcus aureus via chicken anti-protein A IgY antibody. Analytical Methods, 2019 11(29), 3665-3670
10. Zhijian Wang, Fei Xu, Na Yuan,Yuna Niu, Weiwei Lin, Yan Cao, Jinyang Cai, Lin Song, Xin Li, Yixuan Fang, Wenli Zhao, Shaoyan Hu, Suning Chen, Suping Zhang, Jianrong Wang. Rapamycin inhibits pre-B acute lymphoblastic leukemia cells by downregulating DNA and RNA polymerases. Leuk Res. 2014 Aug;38(8):940-7. doi: 10.1016/j.leukres.2014.05.009. Epub 2014 May 24.
11. Suping Zhang,Yuna Niu, Na Yuan, Aihong Zhang, Dan Chao, Qiuping Xu, Lijun Wang, Xueguang Zhang, Wenli Zhao, Yun Zhao, Jianrong Wang. Role of autophagy in acute myeloid leukemia therapy. Chinese Journal of Cancer; doi: 10.5732/cjc.012.10073. 2012
12. Limei Qin, Yaosheng Chen,Yuna Niu, Weiquan Chen, Qiwei Wang, Shuqi Xiao, Anning Li, Ying Xie, Jing Li, Xiao Zhao, Zuyong He, Delin Mo. A deep investigation into the adipogenesis mechanism: profile of microRNAs regulating adipogenesis by modulating the canonical Wnt/beta-catenin signaling pathway. BMC Genomics. May 23;11:320. 2010
13. Shuqi Xiao, Jianyu Jia, Delin Mo, Qiwei Wang, Limei Qin, Zuyong He, Xiao Zhao, Yuankai Huang, Anning Li, Jingwei Yu,Yuna Niu, Xiaohong Liu, Yaosheng Chen Y. Understanding PRRSV infection in porcine lung based on genome-wide transcriptome response identified by deep sequencing*. PLoS One. Jun 29;5(6):e11377. 2011
14. Shuqi Xiao, Delin Mo, Qiwei Wang, Jianyu Jia, Limei Qin, Xiangchun Yu,Yuna Niu, Xiao Zhao, Xiaohong Liu, Yaosheng Chen. Aberrant host immune response induced by highly virulent PRRSV identified by digital gene expression tag profiling. BMC Genomics. Oct 7;11:544. 2010
15. Xiao Zhao, Delin Mo, Anning Li, Wen Gong, Shuqi Xiao, Yue Zhang, Limei Qin,Yuna Niu, Yunxue Guo, Xiaohong Liu, Peiqing Cong, Zuyong He, Chong Wang, Jiaqi Li, Yaosheng Chen. Comparative analyses by sequencing of transcriptomes during skeletal muscle development between pig breeds differing in muscle growth rate and fatness. PLoS One. 6(5):e19774. Epub 2011 May 26. 2011
16. Anning Li, Yaosheng Chen, Xiao Zhao,Yuna Niu, Peiqing Cong, Zongwu Zhang, Weiquan Chen, Wei Jiang, Delin Mo. Characterization and transcriptional regulation analysis of the porcine TNFAIP8L2 gene. Mol Genet Genomics. Epub. Sep;284(3):185-95. Jul 17. 2010
17. Zhisheng Zhang, Delin Mo, Peiqing Cong, Zuyong He, Fei Ling, Anning Li,Yuna Niu, Xiao Zhao, Chunyan Zhou, Yaosheng Chen. Molecular cloning, expression patterns and subcellular localization of porcine TMCO1 gene. Mol Biol Rep. Mar;37(3):1611-8. 2010
主持的科研项目：
1. 河南省自然科学基金，EVI1通过调控自噬参与白血病干细胞的干性维持，2016-2018,10万元，项目编号**3，主持人
2. 国家自然科学基金，BCL3通过STAT3调控NK细胞的功能和机制研究，2018/1/1-2020/12/30，20万元，项目编号**，主持人