刘博雯，1991.10-，博士、讲师、硕士生导师，新乡医学院医学检验学院临床病原生物学教研室。2018年南开大学生物化学与分子生物学博士学位。研究方向为肝癌及乳腺癌发生发展机理，现主要从事特异RNA甲基化修饰在基因表达调控和肿瘤转移中的功能及相关分子机制研究。主持国家自然科学基金青年项目1项。目前在Journal of Hematology & Oncology、oncogene、acta pharmacologica sinica、Journal of Molecular Medicine等杂志发表SCI文章11篇，其中第一作者3篇。
近期发表SCI论文（#为第一作者，*为通讯作者）
[1] Liu, B., Wang, T., Wang, H., Zhang, L., Xu, F., Fang, R., Li, L., Cai, X., Wu, Y., Zhang, W., Ye, L. (2018). Oncoprotein HBXIP Enhances HOXB13 Acetylation and Co-activates HOXB13 to Confer Tamoxifen Resistance in Breast Cancer. J Hematol Oncol, 23; 11(1):26. doi: 10.1186/s13045-018-0577-5.IF=11.059
[2] Liu, B.^#, Wang, T^#.,Li, L.^#, Zhang, L., Liu, Y., Feng, J., Wu, Y., Xu, F., Zhang, W., Ye, L. (2019).Oncoprotein HBXIPInduces PKM2 viaTranscriptionFactor E2F1 toPromoteCellProliferation inBreastCancer. Acta Pharmacol Sin, 40(4):530-538. doi: 10.1038/s41401-018-0015-9. IF=5.064
[3] Wang, T.^#,Liu, B.^#, Guan, Y. (2018). Melatonin Inhibits the Proliferation of Breast Cancer Cells Induced by Bisphenol A via Targeting Estrogen Receptor-related Pathways.Thorac Cancer. 9(3):368-375. doi: 10.1111/1759-7714.12587.IF=2.61
[4] 4)Li, L.^#, Fang, R.^#,Liu, B., Shi, H., Wang, Y., Zhang, W., Zhang, X., Ye, L. (2016). Deacetylation of Tumor Suppressor MST1 in Hippo Pathway Induces Its Degradation through HBXIP-elevated HDAC6 in Promotion of Breast Cancer Growth.Oncogene. 35(31):4048-57. doi: 10.1038/onc.2015.476.IF=7.971
[5] Li, Q., Sun, Y.,Liu, B., Li, J., Hao, X., Ge, W., Zhang, X., Bao, S., Gong, J., Jiang, Z., Qiu, C., Zhao, L., Zhao, Y., Chen, Y., Yang, X., Ding, Y., Wu, Z. (2020). ACT001 Modulates The NF-ΚB/Mnsod/ROS Axis By Targeting IKKΒ To Inhibit Glioblastoma Cell Growth. J Mol Med (Berl). 98(2):263-277. doi: 10.1007/s00109-019-01839-0.IF=4.43
主持的主要科研项目：
1. METTL3介导的STAT3 m6A甲基化修饰在肝癌转移中的作用及分子机制研究，刘博雯，国家自然科学基金2020.01-2022.12，No. **，20.50万元