孙旭武
职称：教授
联系电话：**
传真：+86-
E-mail：sunxuwussd@sina.com
研究方向：质体信号转导、植物抗逆机理、光敏雄性不育的机制及应用
孙旭武，男，博士，教授，博士生导师。
2004年在甘肃农业大学获理学硕士学位，2007年在兰州大学获理学博士学位。2007-2013年在中国科学院植物研究所先后任助理研究员、副研究员。2013-2017年在德国慕尼黑大学任“洪堡****”。2016年被评选为上海市“****”。 目前被聘为河南大学“特区计划”****。
主要研究方向：
1. 植物活性氧依赖的叶绿体反向信号转导：
叶绿体不仅是植物进行光合作用的场所，同时植物叶绿体也是细胞内活性氧产生的重要场所。此外叶绿体还具有合成脂肪和氨基酸、参与植物的免役反应等重要功能。然而，叶绿体的发育及功能依赖于细胞核的调节，而这种调节依赖于由正向信号和反向信号组成的信号网络。正向信号源自于细胞核，调控光合作用相关核基因的表达；反向信号源自叶绿体，负责传递叶绿体的发育和代谢状态传递到细胞核，从而调节正向信号的输出。本课题组通过正向遗传学、反向遗传学、分子生物学、生物信息学等手段挖掘活性氧依赖的质体反向信号通路中的新的信号分子，并研究其生物学功能，完善对这一信号通路的认知。
2. 植物抗逆机理:
自然条件下，植物经常面临盐碱、干旱、病虫害等胁迫环境，并进化出复杂的适应机制。本课题组通过生物信息学、反向遗传学等手段，筛选植物响应盐、干旱等胁迫条件的关键基因，并研究其在农业生产的应用。
3. 光敏雄性不育的机制及应用：
杂交育种对于利用杂种优势提高作物产量有巨大帮助。常用的“三系法”杂交育种操作繁琐，应用十分受限制；以光敏雄性不育系为基础的“二系法”杂交育种操作方便，但是可以使用的遗传位点有限，并且机理很不清楚。本课题组以拟南芥短光照雄性不育突变体psms1为研究基础，通过遗传学、细胞生物学、生物信息学等手段研究植物光敏雄性不育的保守机制，并探索其在农作物杂交育种中使用的可行性。
主持的重要研究项目：
1. 国家自然科学基金面上项目： 过氧化氢介导的质体反向信号的作用机理及其生理功能研究 (**)，2017.01-2020.12。
代表性研究论文和著作：
1) Sun, X.W. *, Xu, D.R., Liu, Z.X., Kleine, T., Leister, D. (2016). Functional relationship between mTERF4 and GUN1 in retrograde signalin. J Exp Bot. 67:3909-3924. (*Corresponding author).
2) Xu, X., Chi, W., Sun, X.W., Feng, P.Q., Guo, H.L., Li, J., Lin, R.C., Lu, C.M., Wang, H.Y., Leister, D., Zhang, L. (2016). Convergence of light and chloroplast signals for de-etiolation through ABI4-HY5 and COP1. Nat Plants. 2:16066.
3) Chi, W., Li, J., He, B.Y., Chai, X., Xu, X.M., Sun, X.W., Jiang, J.J., Feng, P.Q., Zuo, J., Lin, R.C., Rochaix, J.D., Zhang, L. (2016). DEG9, a serine protease, modulates cytokinin and light signaling by regulating the level of ARABIDOPSIS RESPONSE REGULATOR 4. Proc Natl Acad Sci U S A. 113:E3568-76.
4) Guo, H.L., Feng, P.Q., Chi, W., Sun, X.W., Xu, X.M., Li, Y., Ren, D., Lu, C.M., David, Rochaix J, Leister, D., Zhang, L. (2016). Plastid-nucleus communication involves calcium-modulated MAPK signalling. Nat Commun. 7:12173.
5) Feng, P.Q., Guo, H.L., Chi, W, Chai, X, Sun, X.W., Xu, X.M., Ma, J.F., Rochaix, J.D., Leister, D., Wang, H.Y., Lu, C.M., Zhang, L.X. (2016). Chloroplast retrograde signal regulates flowering. Proc Natl Acad Sci U S A. 113:10708-13.
6) Mu, Y, Zou, M.J., Sun, X.W., He, B.Y., Xu, X.M., Liu, Y.N., Zhang, L.X., Chi, W. (2017). BASIC PENTACYSTEINE Proteins Repress ABSCISIC ACID INSENSITIVE4 Expression via Direct Recruitment of the Polycomb-Repressive Complex 2 in Arabidopsis Root Development. Plant Cell Physiol. 58(3):607-621.
7) Yang, H.M., Liao, L.B., Bo, T.T., Zhao, L., Sun, X.W., Lu, X.F., Norling, B., Huang, F. (2014). The Slr0151 protein of the cyanobacterium Synechocystis sp. PCC 6803 is required for efficient repair of photosystem II under high light stress conditions. J Integr Plant Biol. 6:1136-1150.
8) Yin, S.M., Sun, X.W., Zhang, L.X. (2008). An Arabidopsis ctpA homologue is involved in the repair of photosystem II under high light. Chinese Sci Bull. 53:1021-1026.
9) Sun, X.W., Wang, L.Y., Zhang, L.X. (2007). Involvement of DEG5 and DEG8 proteases in the turnover of the photosystem II reaction center D1 protein under heat stress in Arabidopsis thaliana. Chinese Sci Bull. 52:1742-1745.
10) Li, X.Y., Mu, Y., Sun, X.W. *, Zhang, L.X. (2010). Increased sensitivity to drought stress in atlon4 Arabidopsis mutant. Chinese Sci Bull. 55: 3668-3672. (*Corresponding author).
11) Li, J., Sun, X.W. *, Zhang, L.X. (2010). Deg1 is involved in the degradation of the PsbO oxygen-evolving protein of photosystem II in Arabidopsis. Chinese Sci Bull. 27-28:3145-3148. (*Corresponding author).
12) Wei, L., Guo, J., Ouyang, M., Sun, X.W., Ma, J.F., Chi, W., Lu, C.M., Zhang, L.X. (2010). LPA19, a Psb27 homolog in Arabidopsis thaliana, facilitates D1 protein precursor processing during PSII biogenesis. J Biol Chem. 285:21391-21398.
13) Chi, W., Sun, X.W., Zhang, L.X. (2012). The roles of chloroplast proteases in the biogenesis and maintenance of photosystem II. Biochimica et Biophysica Acta. 1817:239-246.
14) Kato, Y., Sun, X.W., Zhang, L.X., Sakamoto, W. (2012). Operative D1 degradation in the photosystem II repair mediated by chloroplastic proteases in Arabidopsis. Plant Physiol. 159:1428-1439.
15) Chi, W., Sun, X.W., Zhang, L.X. (2013). Intracellular signaling from plastid to nucleus. Annu Rev Plant Biol. 64:559-582.
16) Sun, X.W., Ouyang, M., Guo, J.K., Ma, J.F., Lu, C.M., Adam, Z., Zhang, L.X. (2010). The thylakoid protease Deg1 is involved in photosystem-II assembly in Arabidopsis thaliana. Plant J. 62:240-249.
17) Sun, X.W., Fu, T.J., Chen, N., Guo, J.K., Ma, J.F., Zou, M.J., Lu, C.M., Zhang, L.X. (2010). The stromal chloroplast Deg7 protease participates in the repair of photosystem II after photoinhibition in Arabidopsis. Plant Physiol. 152:1263-1273.
18) Sun, X.W., Peng, L.W., Guo, J.K., Chi, W., Ma, J.F., Lu, C.M., Zhang, L.X. (2007). Formation of DEG5 and DEG8 complexes and their involvement in the degradation of photodamaged photosystem II reaction center D1 protein in Arabidopsis. Plant Cell. 19:1347-1361.
19) Sun, X.W., Feng, P.Q., Xu, X.M., Guo, H.L., Ma, J.F., Chi, W., Lin, R.C., Lu, C.M., Zhang, L.X. (2011). A chloroplast envelope bound PHD transcription factor mediates chloroplast signals to the nucleus. Nat Commun. 2:477.
科研获奖：
1. 卢嘉锡青年人才奖, (2011)
讲授课程：
1. 植物学文献阅读（硕、博士生）



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