王慧东
E-mail: wanghd@henu.edu.cn
研究方向：植物与昆虫互作

王慧东，男，博士。2013年6月在南京农业大学获植物保护专业学士学位，2019年6月在南京农业大学获农业昆虫与害虫防治专业博士学位。2019年7月入选河南大学“黄河****”****。


主要研究方向：
以典型的多食性农业昆虫棉铃虫和草地贪夜蛾为研究对象，解析（1）多食性昆虫对植物次生物质的解毒机制；（2）多食性昆虫对寄主植物取食选择的分子基础；（3）害虫抗药性的进化机制。


代表性论文：
1. Wang Huidong, Shi Yu, Wang Lu, Liu Shuai, Wu Shuwen, Yang Yihua, Feyereisen René, Wu Yidong*. CYP6AE gene cluster knockout in Helicoverpa armigera reveals role in detoxification of phytochemicals and insecticides. Nature Communications, 2018, 9: 4820.
2. Wang Huidong, Zhang Jianpeng, Zhao Shan, Zhu Kun Yan, Wu Yidong*. Limited variations in susceptibility to an insecticidal double-stranded RNA (dsvATPaseE) among a laboratory strain and seven genetically differentiated field populations of Tribolium castaneum. Pesticide Biochemistry and Physiology, 2018, 149: 143-148.
3. Wang Jing, Wang Huidong, Liu Shaoyan, Liu Laipan, Tay Wee Tek, Walsh Thomas K, Yang Yihua, Wu Yidong*. CRISPR/Cas9 mediated genome editing of Helicoverpa armigera with mutations of an ABC transporter gene HaABCA2 confers resistance to Bacillus thuringiensis Cry2A toxins. Insect Biochemistry and Molecular Biology, 2017, 87: 147-153. (共同第一作者)
4. Shi Yu, Wang Huidong, Liu Zhi, Wu Shuwen, Yang Yihua, Feyereisen René, Wu Yidong*. Phylogenetic and functional characterization of ten P450 genes from the CYP6AE subfamily of Helicoverpa armigera involved in xenobiotic metabolism. Insect Biochemistry and Molecular Biology, 2018,93:79-91.
5. Wang Jing, Zhang Haonan, Wang Huidong, Zhao Shan, Zuo Yayun, Yang Yihua, Wu Yidong*. Functional validation of cadherin as a receptor of Bt toxin Cry1Ac in Helicoverpa armigera utilizing the CRISPR/Cas9 system. Insect Biochemistry and Molecular Biology, 2016,76:11-17.



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