姜晓文
性 别： 女 出生年月： 1970-06-20
职 称： 副教授 工作单位： 东北农业大学
招生学科1： 090601基础兽医学 招生学科2：
办公电话： ** E-mail： jiangxiaowen@neau.edu.cn

 开设研究生课程情况
课程编号 课程名称 课程级别 学时
106212 神经生物学 博士 32
6.602 动物营养生理生化与调控机理 硕士 32
 近五年主持科研项目概况


 近五年项目获奖概况


 近五年代表性著作、论文

1.Xiaowen Jiang，Bokyung Kim，Haiyue Lin  Chang-Kwon Lee,1 Junghwan Kim,1 Hyun Kang,1 Pilyoung Lee,1 Seung Hyo Jung,1 Hwan Myung Lee, 2 and Kyung-Jong Won 1 Tetrahydrobiopterin Inhibits PDGF-stimulated Migration and Proliferation in Rat Aortic Smooth Muscle Cells via the Nitric Oxide Synthase-independent Pathway. Korean J Physiol Pharmacol. 2010 June; 14(3): 177–183.

2.Won KJ, Lee P, Jung SH, Jiang X, Lee CK, Lin HY, Kang H, Lee HM, Kim J, Toyokuni S, Kim B. 3-morpholinosydnonimine participates in the attenuation of neointima formation via inhibition of annexin A2-mediated vascular smooth muscle cell migration. Proteomics. Jan;11(2) 93-201.2011

3. Jiang XW, Kim B. Cofilin phosphorylation contributes to invasion development of bladder cancer.  The 60th Annual meeting of the korean physiological society.2009.10.

4. 姜晓文，张春燕，于文会，冯国峰,徐 利.复方伊维菌素乳液的毒性试验研究第41 卷 第 9 期 东 北 农 业 大 学 学 报 41(9): 101-105页,2010年

5.于文会，戈胜，姜晓文.防腐生肌膏对创伤组织中VEGF及bFGF mRNA表达水平的影响，中兽医医药杂志，第30卷，第5期，5-7页，2011

6.陆子音，姜晓文，姜龙，康欣，于文会*，乳香提取物对大鼠雪旺细胞增殖和相关蛋白表达影响，中国兽医科学，2013.7

7.戈胜,姜晓文,王志新,于文会*.绞股蓝对雏鸡免疫功能的影响,中兽医医药杂志,第3期,32-34页, 2010.

8．Won KJ, Lee CK, Lee HM, Jung SH, Chang HS, Fang Z, Jiang XW, Kim J, Bae YM, Cho SI, Kwon S, Kim B. Proteomic analysis of Annexin II changed during treatment with SIN-1 in rat aortic in rat aortic smooth muscle: Implication in neointima formation. The 60th Annual Meeting of the Korean Physiological Society, October 22-23, 2008, Seoul, South Korea.

9.Lee CK, Won KJ, Fang Z, Chang HS, Jiang XW, Jung SH, Lee HM, Bae YM, Cho SI, Lee YL, Kim B. Protein tyrosine phosphatase SHP2 is positively involved in vascular smooth muscle cell migration and neointima formation via the ROS-mediated Syk pathway. The 60th Annual Meeting of the Korean Physiological Society, October 22-23, 2008, Seoul, South Korea.
10．Jung SH, Lee HM, Lee CK, Won KJ, Chang HS, Fang Z, Jiang XW, Kim B. Cordycepin, 3’-Deoxyadenosine, attenuates vascular neointimal formation via inhibition of migration and proliferation in response to PDGF-BB. The 60th Annual Meeting of the Korean Physiological Society, October 22-23, 2008, Seoul, South Korea.

11.  Kim J, Lee CK, Won KJ, Fang Z, Chang HS, Jiang XW, Jung SH, Lee HM, Bae YM, Cho SI, Kim B. DJ-1 is involved in the disuse-induced atrophy in rat gastrocnemius. The 60th Annual Meeting of the Korean Physiological Society, October 22-23, 2008, Seoul, South Korea. 

12．Won KJ, Lee CK, Fang Z, Jiang XW, Jung SH, Chang HS, Lee HM, Kim J, Park SH, Kim B. Possible con  tribution of protein tyrosine phosphatase SHP2 to vascular smooth muscle cell migration and neointima formation via the ROS-mediated Syk pathway. Korean Society of Toxicogenomics and Toxicoproteomics 4th International Conference on Toxicogenomics-2008 and Annual Meeting, November 7-8, 2008, Hyatt Regency Incheon, Korea.

13．Jung SH, Won KJ, Lee CK, Lee HM, Chang HS, Fang Z, Jiang XW, Kim J, Bae YM, Cho SI, Kwon S, Kim B. Proteomic analysis of rat aortic smooth muscle treated with SIN-1: Involvement of migration and proliferation. Korean Society of Toxicogenomics and Toxicoproteomics 4th International Conference on Toxicogenomics-2008 and Annual Meeting, November 7-8, 2008, Hyatt Regency Incheon, Korea. 

14．Kim J, Lee CK, Won KJ, Fang Z, Chang HS, Jiang XW, Chung SH, Lee HM, Bae YM, Cho SI, Kim BK. The changes of DJ-1 expression correlates with atrophic condition in rat gastrocnemius muscles and L6 cell lines. Korean Society of Toxicogenomics and Toxicoproteomics 4th International Conference on Toxicogenomics-2008 and Annual Meeting, November 7-8, 2008, Hyatt Regency Incheon, Korea.

15．Fang Z, Jung SH, Jiang X, Won KJ, Lee CK, Kim J, Lee HM, Kim B. SHP2 phosphorylation is positively involved in formation of vascular neointima via the ROS-mediated Syk/p38 MAPK pathway. The 17th Federation Meeting of Korean Basic Medical Scientists, April 23-24, 2009, Suwon, Korea. 

16．Kim J, Lee CK, Won KJ, Fang J, Lee HM, Chung SH, Jin MH, Lin HY, Chun YJ, Jiang XW, Bae YM, Cho S, Kim B. External fixation and starvation induce the expression of atrophy-related MuRF-1 mediated the Akt and Mitogen-activated protein kinase phosphorylation in rat gastrocnemius muscled and L6 myoblasts. The 17th Federation Meeting of Korean Basic Medical Scientists, April 23-24, 2009, Suwon, Korea.

17．Won KJ, Lee CK, Jiang X, Lin HY, Bae YM, Shin HC, Lee HM, Kim J, Kim B. Participation of superoxide in antifungal miconazole-induced cardiomyocyte apoptosis. The 18th Annual Meeting of the Korean Society for Smooth Muscle Research, June 20, 2009, Seoul, South Korea.

18. Lee CK, Won KJ, Lee HM, Jung SH, Kim JH, Lee PY, Lee NK, Jung SH, Na HR, Lin HY, Jiang XW, Bae YM, Cho S, Kim B. Cast immobilization initiates rat gastrocnemius muscle atrophy via MAPK-mediated MuRF-1 pathway. The 18th Annual Meeting of the Korean Society for Smooth Muscle Research, June 20, 2009, Seoul, South Korea.

19. Won KJ, Lee CK, Kim JH, Jung SH, Lin HY, Jiang XW, Lee HM, Kim J, Cho SM, Bae YM, Shin HC, Kim B. Microarray analysis of gene expression in cardiomyocytes exposed to quinolone antibiotics. Korean Society of Toxicogenomics and Toxicoproteomics 5th International Conference on Toxicogenomics (ICT) & 2nd-Toxigenomics intergrated environmental science (TIES)-2008, Sept. 23, 2009, Incheon, Korea.

20.Kim J, Lee CK, Won KJ, Lee HM, Jung SH, Kim JH, Lee PY, Lee NK, Jung SH, Na HR, Lin HY, Jiang XW, Bae YM, Cho S, Kim B. Skeletal muscle atrophy-related muscle-specific ubiquitine-ligase muscle RING Finger-1 expression mediated the mitogen-activated protein kinase in rat gastrocnemius muscle. The 61st Annual Meeting of the Korean Physiological Society, October 29-30, 2009, Gangneung (Kwandong University), South Korea. 

21.Kim J, Lee CK, Won KJ, Lee HM, Jung SH, Kim JH, Lee PY, Lee NK, Jung SH, Na HR, Lin HY, Jiang XW, Bae YM, Cho S, Kim B. Up-regulation of Parkinson’s disease-related DJ-1 protein in immobilization-induced skeletal muscle atrophy. The 61st Annual Meeting of the Korean Physiological Society, October 29-30, 2009, Gangneung (Kwandong University), South Korea. 
 
22.姜晓文, 冯国峰, 徐明星．   伊维菌素对雄性大白鼠生育功能的影响． 中国畜牧兽医. 36卷第6期,174-175页, 2010.
23.姜晓文，张春燕，于文会，冯国峰，徐利．复方伊维菌素乳液的毒性试验研究．东北农业大学学报，41卷第9期，101-105页，2010．
24.周 蔷; 姜晓文; 于文会  陈皮对应激大鼠免疫抑制的缓解和肝肾功能影响  黑龙江畜牧兽医 23. 2013.
25 梁辰; 姜晓文; 刘旭; 权鑫; 于文会  牛乳头状瘤的病理学观察及其病毒基因型分析  中国预防兽医学报 2013.526
26.  肖承男; 姚旭; 姜晓文; 于文会  β-甘露聚糖酶对雏鸡生长性能与血液生化指标的影响 中国家禽 2013/18
27.姜晓文;权鑫;冯欣欣.牛乳头状瘤病毒临床病理学检测及感染C127细胞研究 中国预防兽医学报2016年第01期
28.姜晓文，姜龙，于文会.黄芪水煎剂对免疫应激鸡血清ACTH和CORT含量及下丘脑CRH mRNA表达的影响.中国兽医学报, 2015(11):1819-1823
29.于文, 姜龙, 姜晓文.野菊花水煎剂对免疫应激鸡血清ACTH和CORT含量及下丘脑CRH mRNA表达影响.中国兽医杂志,2015, 51(11)
30.冯欣欣, 于文会, 姜晓文 沙棘黄酮抗衰老作用及对大鼠非特异性免疫功能的影响研究.《中兽医医药杂志》 2015年05期

等40余


 近五年授权的专利等情况
实用新型：1.一种凝胶与照相装置                          第三发明人
          2.自动加液层析柱,                              第三发明人
          3.猫保定器,                                    第三发明人
          4.动物用液压手术台                             第三发明人
          5.带有照明装置的犬阴道扩张器                   第三发明人
发明专利: 1.单诺沙星肺靶向脂质体研究与应用                 第三发明人
          2.预防和治疗鸡败血支原体病中药组合物及其制备方法   第三发明人
 
申请进行中:      


 其他获奖及荣誉称号
1.中国畜牧兽医学会中兽医分会2015学术年会学术论文评选中获三等奖。
2.中国畜牧兽医学会中兽医分会2016学术年会暨中兽药新产品研发研讨会“维尔康”杯征文中，论文获三等奖。
3.中国畜牧兽医学会中兽医分会2017学术年会暨中兽药新产品研发研讨会“惠中”杯征文中，论文获一等奖。
4.中国畜牧兽医学会中兽医分会2018学术年会暨中兽药新产品研发研讨会“绿达生”杯征文中，论文获一等奖。