张瑞莉
性 别: 女 出生年月: 1970-01-31
职 称: 教授 工作单位: 动物医学学院
招生学科1: 基础兽医学 招生学科2: 无
办公电话: E-mail: zhangruili@neau.edu.cn
开设研究生课程情况
课程编号 课程名称 课程级别 学时
206202 兽医病理诊断技术 硕士 64
306305 兽医病理诊断技术实验 硕士 32
206316 病理读片技术 硕士 32
406301 基础兽医学专题 博士 64
近五年主持科研项目概况
1、MDA5与TLR3信号转导在IBDV致雏鸡法氏囊免疫损伤中的作用机制,国家自然科学基金资助项目,主持,2013.1-2016.12,2、TLR4信号通路介导APS调节雏鸡黏膜免疫功能机制研究,黑龙江省自然科学基金项目,主持,2013.1-2015.123、不同分子量段APS影响ND疫苗免疫雏鸡呼吸道-消化道黏膜免疫功能研究,黑龙江省博士后科研启动资助基金项目,主持,2012.1-2014.124、抗新城疫病毒感染中药组方及其作用机制研究,黑龙江省青年基金资助项目,主持,2008.10-2011.10
近五年项目获奖概况
近五年代表性著作、论文
1、Zhang Ruili,Yu Qun ,Shi Guangliang , Liu Rui , Zhang Weiqian,Zhao Xia ,Li Guangxing ,Ge Ming. chTLR4 pathway activation by Astragalus polysaccharide in bursa of Fabricius. BMC Veterinary Research.(2017)13 (1):119. doi:10.1186/s12917-017-1039-y. (IF:1.75, 一区)2、Xie Wanqiu, Ge Ming, Li Guangxing, Zhang Linan, Tang Zequn, Li Ruyue, Zhang Ruili. Astragalus Polysaccharide Protect against Cadmium-Induced Cytotoxicity through the MDA5/NF-κB Pathway in Chicken Peripheral Blood Lymphocytes. Molecules(2017) 22 (10). doi:10.3390/molecules**.(IF=2.861,二区)3、Xie Wanqiu, Lv Ai, Li Ruyue, Tang Zequn, Ma Dexing, Huang Xiaodan, Zhang Ruili, Ge Ming. Agaricus blazei Murill Polysaccharides Protect against Cadmium-induced Oxidative Stress and Inflammatory Damage in Chicken Spleens. Biol Trace Elem Res(2017) doi:10.1007/s12011-017-1189-6. (IF=2.399,三区)4、Liu Wenjing, Ge Ming, Hu Xuequan, Lv Ai, Ma Dexing, Huang Xiaodan, Zhang Ruili. The Effects of Agaricus blazei Murill Polysaccharides on Cadmium-Induced Apoptosis and the TLR4 Signaling Pathway of Peripheral Blood Lymphocytes in Chicken. Biol Trace Elem Res(2017) 180 (1):153-163. doi:10.1007/s12011-017-0969-3.(IF=2.399,三区) 5、Lv Ai, Ge Ming, Hu Xuequan, Liu Wenjing, Li Guangxing, Zhang Ruili. Effects of Agaricus blazei Murill Polysaccharide on Cadmium Poisoning on the MDA5 Signaling Pathway and Antioxidant Function of Chicken Peripheral Blood Lymphocytes. Biol Trace Elem Res(2017) doi:10.1007/s12011-017-1012-4. (IF=2.399,三区)6、Zhang Ruili, Luo Haiyan,Hu Xuequan,Xie Yingying, Tang Zequn, Ge Ming. The effects of cadmium on TLR3 expression in chicken peripheral lymphocytes and spleen, Journal of Trace Elements in Medicine and Biology, 2017, 41s1: 85.(IF=3.755,三区)7、Hu Xuequan, Zhang Ruili, Xie Yingying, Wang Hongmei, Ge Ming. The Protective Effects of Polysaccharides from Agaricus blazei Murill Against Cadmium-InducedOxidant Stress and Inflammatory Damage in Chicken Livers. Biol Trace Elem Res(2017) 178(1):117-126. doi: 10.1007/s12011-016-0905-y. (IF=2.399,三区)8、Song Yangyang, Zhang Ruili, Wang Hongmei, Yan Yan, Ge Ming. Protective Effect of Agaricus blazei Polysaccharide Against Cadmium-Induced Damage on the Testis of Chicken. Biol Trace Elem Res(2017) doi: 10.1007/s12011-017-1196-7.(IF=2.399,三区)9、栾亚男,葛铭,李广兴,谢婉秋,杨贵君,张瑞莉.雏鸡免疫器官中chMDA5的表达与定位. 畜牧兽医学报,2016,47(7):1480-1487.10、王成成,葛铭,刘超男,栾亚男,李广兴,张瑞. IBDV感染雏鸡外周血液淋巴细胞chMDA5信号通路因子表达的动态变化. 畜牧兽医学报,2015,46(5):830-835.11、王成成,王杲强,葛铭,于群,潘龙,张瑞莉.感染传染性法氏囊病病毒的DF-1细胞中chTLR3表达的动态变化. 中国兽医科学,2014,44(12):1304-1308.12、刘瑞,于群,李莹,赵霞,张瑞莉,葛铭.黄芪多糖对雏鸡黏膜sIgA含量的影响研究.中国家禽,2014,36(21):23-26.
近五年授权的专利等情况
抗chMDA5蛋白单克隆抗体抗体及其制备方法和应用. 国家发明专利,7.4,第一名
其他获奖及荣誉称号
中国兽医病理学家、黑龙江省畜牧兽医学会理事。曾获东北农业大学优秀教师称号、主编的《动物病理解剖学实验指导》获东北农业大学优秀教材奖。
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