唐丽杰
性 别: 女 出生年月: 1971-05-18
职 称: 教授 工作单位: 动物医学学院
招生学科1: 预防兽医学 招生学科2:
办公电话: E-mail: tanglijie@163.com
开设研究生课程情况
课程编号 课程名称 课程级别 学时
206106 兽医微生物学专题 硕士课 48
106229 分子病毒学 博士课 48
近五年主持科研项目概况
1.“十二五”农村领域国家科技计划,禽传染性法氏囊病毒感染与变异对宿主免疫应答影响及提高免疫,2015.4-2019.12,95万;
2.国家自然科学基金,表达牛乳铁蛋白肽的重组罗伊氏乳酸杆菌替代抗生素改善断乳仔猪肠道黏膜免疫的分子机制(2017.01-2020.12),62万元;
3. “十三五”国家重点研发项目子课题,表达牛乳铁蛋白肽的重组乳酸菌的研制(2018.7-2020.12),32万元;
4. 哈尔滨市科技创新人才基金,构建表达牛乳铁蛋白肽的绿色生态安全型重组乳酸菌及其功能研究,2014.7-2017.7,7万元;
5. 哈药集团生物疫苗有限公司横向课题,表达猪传染性胃肠炎病毒S蛋白的乳酸乳球菌口服疫苗的研制,2014.1-2017.12,60万元;
6. “十二五”国家科技支撑计划子课题,《型特异性蓝舌病鉴别诊断技术研究》2013.1-2017.12,230万元;
近五年项目获奖概况
猪病毒性腹泻快速检测试剂的研制,黑龙江省科技发明二等奖,2008,第二名。
猪腹泻病毒重要基因及其结构蛋白免疫相关功能研究,黑龙江省高校科学技术一等奖,2010,第二名。
基因工程乳酸菌微生态制剂的分子设计及机制研究,黑龙江省畜牧科技一等奖,2017,第一名。
近五年代表性著作、论文
(1)Xuewei Huang, Yigang Xu, Qingyu Lin, Weilong Guo, Dongfang Zhao, Chunmei Wang, Li Wang, Han Zhou, Yanping Jiang, Wen Cui, Xinyuan Qiao, Yijing Li, Guangpeng Ma & Lijie Tang* (2020) Determination of antiviral action of long non-coding RNA loc during infectious bursal disease virus infection due to enhancement of interferon production, Virulence, 11:1, 68-79, DOI: 10.1080/**.2019.**Virulence. 2020; 11(1): 68–79. (2)Oral delivery of a Lactococcus lactis strain secreting bovine lactoferricin-lactoferrampin alleviates the development of acute colitis in mice. Song L, Xie W, Liu Z, Guo D, Zhao D, Qiao X, Wang L, Zhou H, Cui W, Jiang Y, Li Y, Xu Y*, Tang L*. Appl Microbiol Biotechnol. 2019 Jun 4. (3)Effects of Lactococcus lactis MG1363 producing fusion proteins of bovine lactoferricin–lactoferrampin on growth, intestinal morphology and immune function in weaned piglet. L. Song, X. Qiao, D. Zhao, W. Xie, S.M. Bukhari, Q. Meng, L. Wang, W. Cui,Y. Jiang, H. Zhou, Y. Li, Y. Xu*and L. Tang*. J Appl Microbiol. 2019 Jun 4.(4) Ma S, Qiao X, Xu Y, Wang L, Zhou H, Jiang Y, Cui W, Huang X, Wang X, Tang L, Li Y.Screening and Identification of a Chicken Dendritic Cell Binding Peptide by Using a Phage Display Library. Front Immunol. 2019 Aug 6;10:1853. (5)Identification of antigenic epitopes of monoclonal antibodies against the VP2 protein of the 25 serotype of bluetongue virus. Shuangyu Xie, Yiming Shi, Ruyue Gong, Wen Cui, Yanping Jiang, Min Liu, Li Wang,Han Zhou, Xinyuan Qiao, Yijing Li, Yigang Xu, Lijie Tang*.Veterinary Microbiology, 2018, 219,136-143.(6) Construction and characterization of thymidine auxotrophic (ΔthyA) recombinant Lactobacillus casei expressing bovine lactoferricin. Han Zhou, Xuechun Li, Zongying Wang, Jiyuan Yin, Hongchao Tan, Li Wang, Xinyuan Qiao, Yanping Jiang, Wen Cui, Min Liu, Yijing Li, Yigang Xu and Lijie Tang *. BMC Veterinary Research, 2018, 14:206.(7) Simultaneous detection of Vibrio cholerae, Vibrio alginolyticus, Vibrio parahaemolyticus and Vibrio vulnificus in seafood using dual priming oligonucleotide (DPO) system-based multiplex PCR assay. Xu, Yi-Gang ,Sun, Liu-Mei,Wang, Yu-Sai,Chen, Pei-Pei,Liu, Zhong-Mei,Li, Yi-Jing,Tang, Li-Jie *. Food Control, 2017, 71:64~70.(8) Development of Competitive Enzyme-Linked Immunosorbent Assays for Antibody Detection Based on Bluetongue Virus Monoclonal Antibodies.Han Z, Mingxin Z, Xuechun L, Yigang X, Xinyuan Q, Li W, Wen C, Yanping J, Yijing L, Lijie T*. Viral Immunol. 2018, 31(3):264-271. (9)Expression and purification of the outer shell proteinVP2 of the 4th serotype Bluetongue virus, and preparation of monoclonal antibodies against this protein. Han Zhou, Jiaxuan Li, Shuangyu Xie, Mingxin Zang, Yigang Xu, Xinyuan Qiao,Li Wang, Yanping Jiang, Wen Cui, Yijing Li*, Lijie Tang*. Process Biochemistry.2017, 61: 119–123.(10)Immunogenicity and protective efficacy of orally administered recombinant Lactobacillus plantarum expressing VP2 protein against IBDV in chicken. I. Maqsood, W. Shi, L.Wang, X.Wang, B. Han, H. Zhao, A.M. Nadeem, B.S. Moshin, K. Saima, S.S. Jamal, M.F. Din,Y.Xu, L. Tang* and Y. Li*. Journal of Applied Microbiology 2018,125, 1670—1681.
近五年授权的专利等情况
1. 新兽药注册证书:鸡新城疫、传染性支气管炎、禽流感(H9亚型)三联灭活疫苗(La Sota株+M41株+HZ株)2011新兽药证字21号2011.3.18
2. 中国发明专利:一种用于检测猪流行性腹泻病毒的免疫胶体金试纸条及其制备方法和应用ZL3.6,2015.3
3. 中国发明专利:表达猪传染性胃肠炎病毒S蛋白的重组乳酸乳球菌及其制法,专利号:1.1,国家发明专利,第一名。2009年12月9日.
4. 中国发明专利: 一种作为断乳仔猪饲料添加剂的表达乳铁蛋白重组乳酸菌组合物,专利号:9.1,国家发明专利,2015年9月30第一名。
5. 中国发明专利:用于同时检测猪流行性腹泻病毒、猪传染性胃肠炎病毒以及猪轮状病毒的多重PCR引物组,专利号:2.1,2016年3月30日
其他获奖及荣誉称号
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