＞副教授 姓　　名： 李传星 部　　门： 生物信息学教研室 职　　称： 副教授 学　　历： 博士研究生 职　　务： 办公电话： 办公地址： 分子生物学馆110室 Email： 主要研究方向： 生物信息学 个人简介 　　EDUCATION Harbin Medical University, Harbin, China, 1999-2009 Ph.D. in Pharmacology, 2006, Area of Specialization: Bioinformatics M.S. and B.A. in Medicine, 1999, Combined Bachelors-Masters Degree, Area of Specialization (M.S.): Bioinformatics, Area of Specialization (B.A.): Basic Medicine Science. 　　FOLLOWSHIP AND AWARDS Excellent PhD graduates of Heilongjiang Province, China, 2009 Excellent PhD graduates of Harbin Medical University, China, 2009 First Rank Award for the excellent academic work and research achievement awarded by the educational committee of Heilongjiang Province, China, 2006 Scholarship, Harbin Medical University, 2001-2006 　　RESEARCH EXPERIMENCE Harbin Medical University, College of Bioinformatics Science and Technology Additional Graduate Research: 2009-present -Prediction of Ultrasound-Related Proteins by combining Literature-Mining and Protein-Protein Interaction Network -Dissection the modularity organization principle of protein interaction network -Development of disease miRNAs prioritization algorithm based on their topological features in the microRNA-target dysregulated network. -Development of algorithm to identify inflammatory bowel disease related bacteria and genes by integration of microbial metagenomic and human transcriptomic data Doctoral Research: 2006-2009 -Dissecting the organization of subcellular localizations in protein interaction network. -Construction of miRNA-miRNA synergistic network and analysis of properties of disease miRNA. -Further development of algorithm to identify disease risk single nucleotide polymorphisms (SNPs) by combining multiple genomic data. Master’s Research: 2003-2006 -Development of algorithms to identify disease risk SNPs. -Construction of gene regulatory network based on gene expression profiles. 　　GRANTS Principal Investigators: National Natural Science Foundation of China, 200,000 RMB (Grant Nos. 30600367), 1/2007-12/2009 Principal Investigators: Basic research funds of Harbin Medical University, 30,000 RMB (Grant Nos. BMFH060044), 1/2007-12/2009 　　PUBLICATIONS 　　First author and co-first author 1.Juan Xu, Chuan-Xing Li, Yong-Sheng Li, Jun-Ying Lv, Ye Ma, Ting-Ting Shao, Liang-De Xu, Ying-Ying Wang, Lei Du, Yun-Peng Zhang, Wei Jiang, Chun-Quan Li, Yun Xia, Xia Li. MiRNA-miRNA synergistic network: construction via co-regulating functional modules and disease miRNA topological features. Nucleic Acids Res, 2010. (Co-first author) 2.Chuanxing Li, G. Zhang, X. Li, S. Rao, B. Gong, W. Jiang, D. Hao, P. Wu, C. Wu, L. Du, Y. Xiao, and Y. Wang, A systematic method for mapping multiple loci: an application to construct a genetic network for rheumatoid arthritis. Gene, 2008. 408(1-2): p. 104-11. 3.Chuanxing Li, L. Du, X. Li, B. S. Gong, J. Zhang, and S. Q. Rao, Novel strategies to identify relevant molecular signatures for complex human diseases based on data of identical-by-decent profiles and genomic context. Beijing Da Xue Xue Bao, 2006. 38(1): p. 74-7. 4.Chuanxing Li, Lei Du, Xia Li, Binsheng Gong, Jie Zhang, and Shaoqi Rao, Analysis of Sib-Pair IBD Profiles and Genomic Context for Identification of the Relevant Molecular Signatures for Alcoholism. Lecture Notes in Computer Science, 2005. 3614: p. 845-851. 5.Chuanxing Li, LI Xia, GUO Zheng, GONG Bing-Sheng, TU Kang, Analysis of the mRNA expression similarity of genes in the same gene expression regulatory pathway. Hereditas (Beijing), 2004, 26(6): 929-933. 6.Jiang Wei, Li Xia, Rao Shaoqi, Wang Lihong, Du Lei, Chuanxing Li, Wu Chao, Wang Hongzhi, Wang Yadong, Yang Baofeng, Constructing disease-specific gene networks using pair-wise relevance metric: Application to colon cancer identifies interleukin 8, desmin and enolase 1 as the central elements, BMC systems biology, 2008. 2. 7.Xia Li, Shaoqi Rao, Wei Jiang, Chuanxing Li, Yun Xiao, et.al. Discovery of time-delayed gene regulatory networks based on temporal gene expression profiling. BMC Bioinformatics. 2006. 7:26. 8.Zhang Jie, Li Xia, Wang YQ, ChuanXing Li, Wang QJ, Rao SQ, A novel ensemble decision tree approach for mining genes coding ion channels for cardiopathy subtype, Lecture Notes in Computer Science, 2005. 3614: p. 852-860. 9.Yang Yueying, Wang Haiyun, Li Xia, Xiao Xue, Fei Su, Chuanxing Li, Wang HZ, Rao SQ, Wang YD, A feature ensemble technology to identify molecular mechanisms for distinction between multiple subtypes of lymphoma, Progress in Natural Science, 2008, 18(12), 1491-1500. 　　Talks and poster presentations: 1.An integrative genome-wide strategy for mapping multiple loci for rheumatoid arthritis. Conference on Genetic Analysis Workshop 15, 2006, Tampa, USA. 2.Analysis of Sib-Pair IBD Profiles and Genomic Context for Identification of the Relevant Molecular Signatures for Alcoholism. Conference on Fuzzy Systems and Knowledge Discovery, 2005, Changsha, China. 　　REVIEWER BMC bioinformatics 　　TEACHING EXPERINCE Co-Instructor: Genome Informatics, Harbin Medical University, 2007-2010 -Lectures and dry-lab experiments, emphasis on gene expression profile analysis, gene function annotation and transcriptional regulation. Instructor: Functional Genomics, Harbin Medical University, 2008-2010 -Lectures, emphasis on prediction of gene function and analysis of protein network and disease network. Co-Instructor: Medical Informatics, Harbin Medical University, 2007-2008 -Lectures, emphasis on usage of biological databases and disease biomarker identification.