基本信息科学研究教育教学论文专著
基本信息




工作经历
时间工作经历
2004年起哈尔滨工业大学生命科学与工程系系主任 教授/博士生导师
2011年哈尔滨工业大学生命科学与技术学院 院长 教授/博士生导师




教育经历
1985年获医学学士学位，

1990年获医学硕士学位，

1997年获遗传学博士学位，

1999年完成博士后训练，

2001~2003年哈佛大学医学院访问学者。

主要任职
中国细胞生物学会常务理事

黑龙江省细胞生物学学会理事长

黑龙江省遗传学会常务理事

黑龙江省生物医学工程学会常务理事

国家自然科学基金委员会评审专家

国家科技部科技进步奖函评专家

美国得克萨斯A&M大学健康医学中心，IBT Adjunct faculty member

遗传杂志编委

航天医学与工程杂志编委

中华医学遗传学杂志编委

国际遗传学杂志编委

研究领域
肿瘤细胞分子生物学肿瘤糖生物学肿瘤代谢组学空间细胞分子生物学与航天医学 主要研究方向:

肿瘤细胞的基因表达调控肿瘤细胞分子生物学肿瘤诊断的分子标记物细胞的辐射损伤与修复


科研奖项
国家教育部高校科技奖 二等

黑龙江省自然科学奖（著作类） 二等

黑龙江省政府科技进步奖 二等

全国肿瘤大会(第一届) 优秀论文奖

其他省部及厅局级奖项多项

教学成果
国家级教学成果奖 二等， 第一完成人

黑龙江省优秀教学成果奖 一等, 第一完成人

论文期刊
2012：

Synergistic Effects of Incubation in Rotating Bioreactors and Cumulative Low Dose 60Co γ-ray Irradiation on Human Immortal Lymphoblastoid Cells. Microgravity Science and Technology: 2012, 24 (5):335-344Recent advances in sialic acid-focused glycomics. Journal of Proteomics. 2012.5Identification and characterization of a novel gene, c1orf109, encoding a CK2 substrate that is involved in cancer cell proliferation. Journal of Biomedical Science 2012.5MARVELD1 inhibited cell proliferation and enhance chemosensitivity via increasing expression of p53 and p16 in hepatocellular carcinoma. Cancer science. 2012.3Recent Advances in the Synthesis and Biomedical Applications of Chain-End Functionalized Glycopolymers. Journal of Carbohydrate Chemistry. 2012.2A three-dimensional in vitro culture model for primary neonatal rat ventricular myocytes. Current applied physics. 2012.5Rotary culture promotes the proliferation of MCF-7 cells encapsulated in three- dimensional collagen-alginate hydrogels via activation of ERK1/2-MAPK pathway. 2012.2 2011:

Fabrication of engineered heart tissue grafts from alginate/collagen barium composite microbeads. Biomedical materials. 2011.5Knockdown of Rab5a expression decrease cancer cell motility and invasion by integrin-mediated pathway. J Biomed Sci. 2011,17;18:58Identification of mouse MARVELD1 as a candidate microtubule-associated protein that inhibites cell-cycle progression and migration. Molecules and Cells. 2011;31(3)：267-274.Human Serum N-Glycan Profiles Are Age and Sex Dependent. age aging. 2011;40(5):568-75 2010-2007:

Simulated weightlessness leads to structural aberrant spindle apparatus and cell cycle arrest in NIH3T3 fibroblast cells. Space Medicine & Medical Engineering. 2010;23(6)416-418Identification and characterization of MARVELD1, a novel nuclear protein that is downregulated in multiple cancers and silenced by DNA methylation. Cancer Letters. 2009;282:77-86.Identification of Interaction between MARVELD1 and Importinβ1. Chin J. Biochem. & Mol. Bio. 2009;25:735-739.Silencing LRP1B with huge transcript by RNAi method. HEREDITAS. 2009;31:36-42.The study of damage of rat terminal differentiation PC12 cell under γ-radiation and simulated microgravity. Progress in Modern Biomedicine. 2008;8(12):2204-2207Cloning of Novel Tumor Metastasis-Related Genes from the Highly Metastatic Human Lung Adenocarcinoma Cell Line Anip973. Journal of Genetics and Genomics. 2007;34: 189-195Insulin Receptor Activation in Solitary Fibrous Tumors. J. of Pathology. 2007;211:550-554.Genomic and functional evidence for an ARID1A tumor suppressor role. Genes Chromosomes Cancer. 2007;46:745-750.UTRN on chromosome 6q24 is mutated in multiple tumors. Oncogene 2007;26: 6220-6228.