姓 名:
杨运煌 性 别:
男
职 务:
职 称:
研究员
通讯地址:
武汉市武昌区小洪山西30号 邮政编码:
430071
电子邮件:
yang_yh@wipm.ac.cn 电 话：



简历：
男，博士，研究员，2005年于中国科学院武汉物理与数学研究所获博士学位。2005年4月至2009年2月在美国School of Medicine, Wayne State University从事博士后工作。2009年3月至2014年12月在Miami University, Northeast Structural Genomics (NESG) consortium从事高级研究****工作。 2014年12月任中科院武汉物理与数学研究所研究员。长期从事基于基因组学的生物大分子溶液结构，动力学和功能研究，发表论文30余篇, 其中第一作者论文11篇。
研究领域：
　　(1) 应用磁共振波谱(NMR)和其它生物物理技术，发展生物大分子复合物（RNA/DNA/protein-protein complex) 的结构和动力学研究的新方法
　　(2) 基于基因组学的生物大分子结构和功能研究
(3) 与癌症相关(Human Cancer Pathway Protein Interaction Network, HCPIN)的蛋白质结构和功能研究
社会任职：

获奖及荣誉：

代表论著：
　
　　Yunhuang Yang, Theresa A. Ramelot, Hsiau-Wei Lee, Rong Xiao, John K. Everett, Gaetano T. Montelione, James H. Prestegard, and Michael A. Kennedy. Solution structure of a C-terminal fragment (175-257) of CV_0373 protein from Chromobacterium violaceum adopts a winged helix-turn-helix (wHTH) fold. Journal of Biomolecular NMR, 60:197-202, 2014.
　　Yunhuang Yang, Theresa A. Ramelot, Hsiau-Wei Lee, Rong Xiao, John K. Everett, Gaetano T. Montelione, James H. Prestegard, and Michael A. Kennedy. Solution structure of the free Za domain of human DLM-1 (ZBP1/DAI), a Z-DNA binding domain. Journal of Biomolecular NMR, 60:189-195, 2014.
　　Yunhuang Yang, Theresa A. Ramelot, Shuisong Ni, Robert M. McCarrick, and Michael A. Kennedy. Applications of NMR-based PRE and EPR-based DEER spectroscopy to homodimer chain exchange characterization and structure determination. Methods in Molecular Biology, 215-227, 2014.
　　Yunhuang Yang, Theresa A. Ramelot, Shuisong Ni, Robert M. McCarrick, and Michael A. Kennedy. Measurement of rate constants for homodimer subunit exchange using double electron-electron resonance and paramagnetic relaxation enhancements. Journal of Biomolecular NMR, 55, 47-58, 2013.
　　Yunhuang Yang, Theresa A. Ramelot, John R. Cort, Maite Garcia, Adelinda Yee, Cheryl H. Arrowsmith, and Michael A. Kennedy. Solution NMR structure of hypothetical protein CV_2116 encoded by a viral prophage element in Chromobacterium violaceum. International Journal of Molecular Sciences, 13, 7354-7364, 2012.
　　Yunhuang Yang, Theresa A. Ramelot, John R. Cort, Huang Wang, Colleen Ciccosanti, Mei Jiang, Haleema Janjua, Thomas B. Acton, Rong Xiao, John K. Everett, Gaetano T. Montelione, and Michael A. Kennedy. Solution NMR structure of Dsy0195 homodimer from Desulfitobacterium hafniense: first structure representative of the YabP domain family of proteins involved in spore coat assembly. Journal of Structural and Functional Genomics; 12, 175-179, 2011.
　　Yunhuang Yang, Theresa A. Ramelot, John R. Cort, Dongyan Wang, Colleen Ciccosanti, Keith Hamilton, Rajesh Nair, Burkhard Rost, Thomas B. Acton, Rong Xiao, John K. Everett, Gaetano T. Montelione, and Michael A. Kennedy. Solution NMR structure of photosystem II reaction center protein Psb28 from Synechocystis sp. strain PCC 6803. Proteins: Structure, Function, and Bioinformatics, 79, 340-344, 2011.
　　Yunhuang Yang, Theresa A. Ramelot, Robert M. McCarrick, Shuisong Ni, Erik A. Feldmann, John R. Cort, Huang Wang, Colleen Ciccosanti, Mei Jiang, Haleema Janjua, Thomas B. Acton, Rong Xiao, John K. Everett, Gaetano T. Montelione, and Michael A. Kennedy. Combining NMR and EPR methods for homodimer protein structure determination. Journal of American Chemical Society, 132, 11910-11913, 2010.
　　Yunhuang Yang, David Hoyt, and Jianjun Wang. A complete NMR spectral assignment of the lipid-free mouse apolipoprotein A-I (apoAI) C-terminal truncation mutant, apoAI (1-216). Biomolecular NMR Assignments, 1, 109-111, 2007.
　　Yunhuang Yang, Guoyun Bai, Xu Zhang, Chaohui Ye, and Maili Liu. ¹H NMR spectroscopic evidence of interaction between ibuprofen and lipoproteins in human blood plasm. Analytical Biochemistry, 324, 292-297, 2004.

承担科研项目情况：