姓名：沈爱国
邮箱：agshen@whu.edu.cn
职称：教授/博士生导师

教育&学术经历
教育经历
博士，武汉大学，化学与分子科学学院，分析化学，2001-2006
本科，湖北大学，化学与材料科学学院，化学教育，1997-2001
学术经历
武汉大学印刷与包装系，包装工程研究室，教授，2020/9/9
武汉大学化学与分子科学学院，测试中心，教授，2016/12-2020/8
武汉大学化学与分子科学学院，测试中心，副教授，2008/12-2016/11
德国图宾根大学，物理与理论化学所，博士后（王宽诚奖学金），2011/6-2012/6
武汉大学化学与分子科学学院，测试中心，讲师，2006/7-2008/11

研究方向
1.等离激元相关的纳米材料与检测器件
2.基于包装的化学测量科学与技术
3.疾病（早期）诊断的拉曼光谱新技术与新仪器
4.面向食品、环境及医疗的现场、快速分析的表面增强拉曼检测新原理和新器件
5.新型表面增强拉曼光谱纳米探针用于多元传感分析和生物成像

教授课程
1.《现代仪器分析方法与实践》（拉曼光谱）（研究生）
2.《分析科学进展》（研究生）
3.《材料科学进展》（研究生）
4.《激光分析》（研究生）
5.《人文化学》（本科生通识课）
6.《仪器分析实验—红外与拉曼光谱》（本科生）

代表性论著（通讯作者或第一作者）
1.Yi Zeng, Jia-Qiang Ren, Ai-Guo Shen*, Ji-Ming Hu, Splicing nanoparticles-based ‘Click’ SERS could aid multiplex liquid biopsy and accurate cellular imaging, Journal of the American Chemical Society, 2018, 140, 10649-10652. (IF=14.612)
2.Ai-Guo Shen, Li-Fang Chen, Wei Xie, Jun-Cheng Hu, Ao Zeng, Ryan M Richards, Ji-Ming Hu*, Triplex Au-Ag-C core-shell nanoparticles as a novel Raman labels, Advanced Functional Materials, 2010, 20, 969-975. (IF=15.621)
3.Wei Zhu, Meng-Yue Gao, Qing Zhu, Bin Chi, Ling-Wen Zeng, Ji-Ming Hu, Ai-Guo Shen*, Monodispersed plasmonic prussian blue nanoparticles for zero-background SERS/MRI-guided phototherapy, Nanoscale, 2020, 12, 5, 3292-3301. (IF=6.895)
4.Meng-yue Gao, Qiao Chen, Wei Li, Ai-Guo Shen*, Ji-Ming Hu, Combined surface-enhanced Raman scattering emissions for high-throughput optical labels on micrometer-scale objects, Analytical Chemistry, 2019, 91, 21, 13866-13873. (IF=6.785)
5.Wei Fang, Zi-He Cheng, Yin Yang, Ai-Guo Shen*, Ji-Ming Hu, Ultrafast and surfactant-free synthesis of bimetallic alloy nanopeanuts: First-longitudinal-then-radial growth starting from slightly inert metal seeds, Applied Materials Today, 2019, 15, 252-262. (IF=8.352)
6.Yi Zeng, Kevin M. Koo, Matt Trau*, Ai-Guo Shen*, Ji-Ming Hu, Watching SERS glow for multiplex biomolecular analysis in the clinic: A review, Applied Materials Today, 2019, 15, 431-444. (IF=8.352)
7.Xiang-Ru Bai, Li-Hua Wang, Jia-Qiang Ren, Xiang-Wei Bai, Ling-Wen Zeng*, Ai-Guo Shen*, Ji-Ming Hu, Accurate clinical diagnosis of liver cancer based on simultaneous detection of ternary specific antigens by magnetic induced mixing surface-enhanced Raman scattering emissions, Analytical Chemistry, 2019, 91, 2955-2963. (IF=6.785)
8.Qian Lv, Huan Min, Dong-Ban Duan, Wei Fang, Gui-Ming Pan, Ai-Guo Shen*, Qu-Quan Wang, Guang-Jun Nie*, Ji-Ming Hu, Total aqueous synthesis of Au@Cu2-xS core-shell nanoparticles for in vitro and in vivo SERS/PA imaging-guided photothermal cancer therapy, Advanced Healthcare Materials, 2019, 8 (2), **. (IF=7.367)
9.Qian Lv, Meng-Yue Gao, Zi-He Cheng, Qiao Chen, Ai-Guo Shen*, Ji-Ming Hu, Rational synthesis of hollow cubic CuS@Spiky Au core-shell nanoparticles for enhanced photothermal and SERS effects, Chemical Communications, 2018, 54, 13399-13402. (IF=5.996)
10.Jun-Rong Li, Guan-Nan Zhang, Jing Wang, Ivan S. Maksymov, Andrew D. Greentree, Ji-Ming Hu, Ai-Guo Shen*, Yu-Ling Wang*, Matt Trau*, Facile one-pot synthesis of nanodot-decorated gold-silver alloy nanoboxes for single-particle surface-enhanced Raman scattering activity, ACS Applied Materials & Interfaces, 2018, 10, 32526-32535. (IF=8.758)
11.Xiang-Ru Bai, Yi Zeng, Xiao-Dong Zhou, Xiao-Hua Wang, Ai-Guo Shen*, Ji-Ming Hu, Environmentally safe mercury (II) ions aided zero-background and ultrasensitive SERS detection of dipicolinic acid, Analytical Chemistry, 2017, 89, 10335-10342. (IF=6.785)
12.Yi Zeng, Jia-Qiang Ren, Shao-Kai Wang, Jia-Ming Mai, Bing Qu, Yan Zhang, Ai-Guo Shen*, Ji-Ming Hu, Rapid and reliable detection of alkaline phosphatase by a hot spots amplification strategy based on well-controlled assembly on single nanoparticle, ACS Applied Materials & Interfaces, 2017, 9, 29547-29553. (IF=8.758)
13.Yi Zeng, Jia-Qiang Ren, Ai-Guo Shen*, Ji-Ming Hu*, Field and pretreatment-free detection of heavy-metal ions in organic polluted water through an alkyne-coded SERS test kit, ACS Applied Materials & Interfaces, 2016, 8, 27772-27778. (IF=8.758)
14.Yong Chen, Jia-Qiang Ren, Xia-Guang Zhang, De-Yin Wu, Ai-Guo Shen*, Ji-Ming Hu*, Alkyne-modulated surface-enhanced Raman scattering-palette for optical interference-free and multiplex cellular imaging, Analytical Chemistry, 2016, 88, 6115-6119. (IF=6.785)
15.Wei Fang, Xin-Wei Zhang, Yong Chen, Liang Wan, Wei-Hua Huang, Ai-Guo Shen*, Ji-Ming Hu*, Portable SERS-enabled micropipettes for microarea sampling and reliably quantitative detection of surface organic residues, Analytical Chemistry, 2015, 87, 9217-9224. (IF=6.785)
16.Yi Zeng, Jin-Ju Pei, Li-Hua Wang, Ai-Guo Shen*, Ji-Ming Hu, A sensitive sequential "on/off" SERS assay for heparin with wider detection window and higher reliability based on the reversed surface charge changes of functionalized Au@Ag nanoparticles, Biosensors and Bioelectronics, 2015, 66, 55-61. (IF=10.257)
17.Li-Hua Wang, Yi Zeng, Ai-Guo Shen*, Xiao-Dong Zhou, Ji-Ming Hu*, Three-dimensional nano-assemblies of noble metal nanoparticle-infinite coordination polymers as specific oxidase mimetics for degradation of methylene blue without adding any cosubstrate, Chemical Communications, 2015, 51, 2052-2055. (IF=5.996)
18.Gan Qu, Guan-Nan Zhang, Zi-Tong Wu, Ai-Guo Shen*, Jian-Bo Wang, Ji-Ming Hu*, A "turn-off" SERS assay of heparin with high selectivity based on heparin-peptide complex and Raman labelled gold nanoparticles, Biosensors and Bioelectronics, 2014, 60, 124-129. (IF=10.257)
19.Zi-Tong Wu, Yi-Zhen Liu, Xiao-Dong Zhou, Ai-Guo Shen*, Ji-Ming Hu*, A "turn-off" SERS-based detection platform for ultra-sensitive detection of thrombin based on enzymatic assays, Biosensors and Bioelectronics, 2013, 44, 10-15. (IF=10.257)

科研项目
1.主持人，企业横向项目，“室内空气微生物快速检测关键技术及设备研发”，2020-2021，50万。
2.主持人，国家自然科学基金面上项目，“突破衍射与颜色双重极限的SERS显微成像新技术研究”，2019-2022，65万（直接经费），批准号：**。
3.主持人，国家自然科学基金面上项目，“突破衍射极限的针尖增强拉曼显微镜在细菌生物被膜无标记、高灵敏检测中的应用”，2015-2018，90万，批准号：**。
4.主持人，国家重大科学仪器设备开发专项子项目，“激光拉曼光谱气体分析仪的研制”，2012-2015，218万，批准号：2012YQ**。
5.主持人，国家自然科学基金面上项目，“原位、活体检测植物激素的SERS探针新技术”，2012-2015，60万，批准号：**。
6.主持人，国家自然科学基金青年科学基金项目，“新型复合拉曼探针用于胃癌早期诊断的研究”，2008-2010，20万，批准号：**。
7.主持人，中国石油科技创新基金项目，“改善二氧化碳驱油关键技术研究”，2008-2010，20万。

学术组织任职、兼职等
1.中国物理学会光散射专业委员会副秘书长
2.湖北省化学化工学会谱学专业委员会秘书长


邀请报告
1.沈爱国, 新型SERS标记：从理解到创新, 第二十届全国光散射学术会议, 中国, 苏州, 2019.11.3。
2.沈爱国, 叁键SERS——化学生物传感器零背景、高通量信号输出, 第十四届全国化学传感器学术会议, 中国, 大同, 2019.8.16。
3.Shen Ai-Guo, ‘Click SERS’ for multiplex liquid biopsy and accurate cellular imaging, International Conference of Raman Spectroscopy (ICORS XXVI), Jeju, Korea, 26-31 August 2018.
4.Shen Ai-Guo, Multi-color and zero-background SERS cellular imaging, International Conference on SERS (SERS-2017), Xiamen, China, 5-9 December 2017.
5.沈爱国, “点击”SERS光谱及其在生物医学分析中的应用, 第十九届全国光散射学术会议, 中国, 广州, 2017.12.1-11.5。
6.沈爱国, 新型SERS检测试剂和器件在快检分析中的应用, 第十九届全国光散射学术会议卫星会暨五邑大学应用物理与材料学院第三届青年教授论坛, 中国, 江门, 2017.11.30-12.1。
7.Shen Ai-Guo, Multi-color and zero background cellular imaging based on alkyne-coded SERS technique, International Conference on BioNano Innovation Australia 2017, Brisbane, Australia, 25-27 September 2017.
8.沈爱国, SERS用于多元、定量检测与活细胞靶向成像, 第十八届全国分子光谱学学术会议,中国, 苏州, 2014.10.31-11.3。
9.沈爱国, SERS生物成像应用的一点思考, 第二届SERS前沿研讨会, 中国, 北京, 2013.12.8。
10.沈爱国, SERS标记材料新进展, 第十七届全国光散射学术会议, 中国,西安, 2013.10.19-22。