姓名
韩正刚
性别
男

民族
汉族
籍贯
陕西渭南

出生日期
1981.6
婚姻状况
是

学历
博士研究生
联系电话
159-2726-2705

专业
生物化学
邮箱
zhengganghan@whpu.edu.cn

教育经历
2009.11 - 2015.09 Institute of Biochemistry, University of Luebeck, Germany.获自然科学博士学位；
2005.9 - 2008.6中国科学院武汉病毒研究所获理学硕士学位；
2000.9 - 2005.6沈阳农业大学获动物医学学士学位。

工作经历
2015.11 –至今武汉轻工大学生物与制药工程学院讲师；
2008.7 - 2009.10香港基因公司市场部武汉产品专员。

发表文章
Yang J,Han Z. Understanding the Positional Binding and Substrate Interaction of a Highly Thermostable GH10 Xylanase from Thermotoga maritima by Molecular Docking. Biomolecules.2018, 8, doi: 10.3390/biom**.
Han Z, Shang-Guan F, Yang J. Characterization of a novel cold-active xylanase from Luteimonas species. World J Microbiol Biotechnol.2018, 34, 123, doi: 10.1007/s11274-018-2505-9.
Han Z, Zhang J, Jiang X, Yang J. Gene dosage and coexpression with endoplasmic reticulum secretion-associated factors improved the secretory expression of α-galactosidase. Protein Expr Purif. 2019,153: 83-91.
Liu Z,Han Z, Yu X, Wen G, Zeng C. Crystal Structure of the Catalytic Domain of MCR-1 (cMCR-1) in Complex with d-Xylose. Crystals 2018, 8, 172.
Li Y, Wang P, Hu C, Wang K, Chang Q, Liu L, Han Z, Shao Y, Zhai Y, Zuo Z, Mak M, Gong Z, Wu Y. Protein corona of airborne nanoscale PM2.5 induces aberrant proliferation of human lung fibroblasts based on a 3D organotypic culture. Sci Rep.2018, 8, 1939, doi: 10.1038/s41598-018-20445-7.
Yang JK, Xiong W, Chen FY, Xu L,Han ZG. Aromatic amino acids in the cellulose binding domain of Penicillium crustosum endoglucanase EGL1 differentially contribute to the cellulose affinity of the enzyme. PLoS One.2017, 12, e**. doi: 10.1371/journal.pone.**.
Xiong W, Yang JK, Chen FY,Han ZG. The catalytic domain of Penicillium crustosum endoglucanase EGL1 has cellulose-binding capacity and cellulolytic activity. Enzyme Microb Technol.2017, 97, 71-81, doi: 10.1016/j.enzmictec.2016.11.007.
Han Z, Sakai N, Böttger LH, Klinke S, Hauber J, Trautwein AX, Hilgenfeld R. Crystal Structure of the Peroxo-diiron(III) Intermediate of Deoxyhypusine Hydroxylase, an Oxygenase Involved in Hypusination. Structure.2015, 23, 882-892, doi: 10.1016/j.str.2015.03.002.
Zhou P,Han Z, Wang LF, Shi Z. Identification of immunogenic determinants of the spike protein of SARS-like coronavirus. Virol Sin.2013, 28, 92-6, doi: 10.1007/s12250-013-3292-y.
Hou YX, Peng C,Han ZG, Zhou P, Chen JG, Shi ZL. Immunogenicity of the spike glycoprotein of bat SARS-like coronavirus. Virol Sin.2010, 25, 36-44, doi: 10.1007/s12250-010-3096-2.
Hou Y, Peng C, Yu M, Li Y,Han Z, Li F, Wang LF, Shi Z. Angiotensin-converting enzyme 2 (ACE2) proteins of different bat species confer variable susceptibility to SARS-CoV entry. Arch Virol.2010, 155, 1563-9, doi: 10.1007/s00705-010-0729-6.
Zhou P,Han Z, Wang LF, Shi Z. Immunogenicity difference between the SARS coronavirus and the bat SARS-like coronavirus spike (S) proteins. Biochem Biophys Res Commun. 2009, 387, 326-9, doi: 10.1016/j.bbrc.2009.07.025.
Li Y, Wang J, Hickey AC, Zhang Y, Li Y, Wu Y, Zhang H, Yuan J,Han Z, McEachern J, Broder CC, Wang LF, Shi Z. Antibodies to Nipah or Nipah-like viruses in bats, China. Emerg Infect Dis.2008, 14, 1974-6, doi: 10.3201/eid1412.080359.
Ren W, Qu X, Li W, Han Z, Yu M, Zhou P, Zhang SY, Wang LF, Deng H, Shi Z. Difference in receptor usage between severe acute respiratory syndrome (SARS) coronavirus and SARS-like coronavirus of bat origin. J Virol.2008, 82, 1899-907.