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中南民族大学生命科学学院导师教师师资介绍简介-李先涛

本站小编 Free考研考试/2021-07-31


李先涛,博士,教授
动物生理学教研室
主要教育及科研经历
2002-2005 德国马堡大学学习并获博士学位(Ph.D)。
2007-2009 美国耶鲁大学从事研究工作(Research Scientist)。
研究方向
近年来主要运用电生理与分生等技术相结合的方法,对心、脑血管中钾离子通道生理作用及结构与功能的关系进行了系统的研究,并发表相关论文,为寻找设计治疗相关疾病的药物提供了参考。
近五年发表文章(*为通讯作者):
1.Qiu XY,Li K, Li XQ, Li XT*. The inhibitory effects of nifedipine on outward voltage-gated potassium currents in mouse neuroblastoma N2A cells. Pharmol Rep. 2016; 68:631-637
2.Hu XM, Li XQ, Li XT*The tau-induced reduction of mRNA levels of Kv channels in human neuroblastoma SK-N-SH Cells. J Mol Neurosci. 2016;58(2):306-311
3.LiXT*, Li XQ, Hu XM, Qiu XY. The inhibitory effects of Ca2+ channel blocker nifedipine on rat kv2.1 potassium channels. PLoS One. 2015; 10(4):e**.
4.Li XT*, Qiu XY. 17β-estrdiol upregualted expression of α and β subunits of larger conductance calcium-activated K+ channels (BK) via estrogen receptor β. J Mol Neurosci. 2015;56(4):799-807
5.Li XT*, Hu XM, Li XQ, Hao XR. Overexpression of tau downregulated the mRNA levels of Kv channels and improved proliferation in N2A cells.PLoS One. 2015; 10(1):e**.
6.Hao XR, Li XT*.The knockdown of TASK-1 channels improved the proliferation of N2A cells. J Mol Neurosci. 2015; 55(2):314-317.
7.Hao XR, Li XQ, Li XT*. 17β-estradiol downregulated the expression of TASK-1 channels in mouse neuroblastoma N2A cells. J Membr Biol. 2014; 247(3):273-279.
8.Li XQ, Hao XR, Chen B, Li XT*. Acute blockage of voltage-gated K+ currents by 17β-estradiol in mouse neuroblastoma N2A cells. Neuroreport. 2014; 25(8):574-579.
9.Li XT, ZhengSC, Dong XH, Xiao J. 17β-Estradiol Inhibits Outward Voltage-Gated K (+) Currents in Human Osteoblast-Like MG63 Cells. J Membr Biol. 2013; 246(1):39-45.
10.Li XT, Dong XH, Zheng SC, Xiao J. Expression and localization of TASK-1, TASK-2 and TASK-3 channels in human osteoblast-like MG63 cells. Oncol Lett. 2013; 5(3):865-869.
11.Li XT, Surguchev A, Bian SM, Dhasakumar N, Santos-Sacchi J. Extracellular chloride regulation of Kv2.1,contributor to the major outward Kv current in mammalian outer hair cells. Am J Physiol, 2012, 302(1):C296-306.




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