姓 名：舒广文

出生年月：1984年3月

民 族：汉

职 称：副教授

学科专业：中药学

研究方向：传统药物治疗肝脏疾病的活性物质与作用机理

电子邮箱：shuguangwen@whu.edu.cn

简 历：

　　2002/09至2006/06，武汉大学，生命科学学院，学士。

　　2006/09至2011/06，中国科学院上海生命科学研究院，生物化学与细胞生物学研究所，博士。

　　2011/07至今，中南民族大学，药学院，教师。

代表性研究成果

1.Meixian Xiang, Hanwen Su, Yajing Hu, Yun Hu, Tianming Yang, Guangwen Shu, Chemical composition of total flavonoids from Salvia chinensia Benth and their pro-apoptotic effect on hepatocellular carcinoma cells: potential roles of suppressing cellular NF-kappaB signaling. Food and Chemical Toxicology, 62 (2013) 420-426.

2.Guangwen Shu, Xue Mi, Jian Cai, Xinlin Zhang, Wu Yin, Xinzhou Yang, You Li, Lvyi Chen, Xukun Deng, Brucine, an alkaloid from seeds of Strychnos nux-vomica Linn., represses hepatocellular carcinoma cell migration and metastasis: the role of hypoxia inducible factor 1 pathway. Toxicology Letters, 222 (2013) 91-101.

3.Fufeng Chen, Hui Xiong, Jianxia Wang, Xin Ding, Guangwen Shu, Zhinan Mei, Antidiabetic effect of total flavonoids from Sanguis draxonis in type 2 diabetic rats. Journal of Ethnopharmacology, 149 (2013) 729-736

4.G.uangwen Shu, Tianming Yang, Chaoyuan Wang, Hanwen Su, Meixian Xiang, Gastrodin stimulates anticancer immune response and represses transplanted H22 hepatic ascitic tumor cell growth: Involvement of NF-kappaB signaling activation in CD4+ T cells. Toxicology and Applied Pharmacology, 269 (2013) 270-279.

5.Xiangpei Zhao, Guangwen Shu, Lvyi Chen, Xue Mi, Zhinan Mei, Xukun Deng, A flavonoid component from Docynia delavayi (Franch.) Schneid represses transplanted H22 hepatoma growth and exhibits low toxic effect on tumor-bearing mice. Food and Chemical Toxicology, 50 (2012) 3166-3173.

6.Xinzhou Yang, Chunping Tang, Ping Zhao, Guangwen Shu, Zhinan Mei, Antimicrobial constituents from the tubers of Bletilla ochracea. Planta Medica, 78 (2012) 606-610.

7.Tao Zheng, Guangwen Shu, Zhanzhan Yang, Shasha Mo, Yin Zhao, Zhinan Mei, Antidiabetic effect of total saponins from Entada phaseoloides (L.) Merr. in type 2 diabetic rats. Journal of Ethnopharmacology, 139 (2012) 814-821.

8.G.uangwen Shu, Yunneng Tang, Yi Zhou, Chen Wang, Jianguo Song, Zac1 is a histone acetylation-regulated NF-kappaB suppressor that mediates histone deacetylase inhibitor- induced apoptosis. Cell Death and Differentiation, 18 (2011) 1825-1835.