出生年月 ：1983年2月

民 族：苗族

职 称：副教授

学科专业：药物分析、化学计量学

研究方向：药物代谢动力学方法研究；中药质量控制方法研究；化学计量学方法及其创新

性应用研究；

定量构效、谱效方法研究；

电 话：**

电子邮箱：fuhaiyan@mail.scuec.edu.cn

简 历：

2005年6月毕业于湖南大学化学化工学院，获理学学士学位； 2005年9月在湖南大学化学生物传感与计量学国家重点实验室攻读分析化学硕士，2007年9月获提前攻博资格，于2010年12月毕业获得湖南大学分析化学专业理学博士学位。2010年12月至今，任教于中南民族大学。助教（2010年12月-2011年6月）、讲师（2011年6月-2013年6月）、副教授（2013年6月-至今）、硕士生导师（2013年6月至今）。任教期间为美国化学会会员，并于2012年起应邀担任《Food Analytical Methods》和《Journal of the American Oil Chemists' Society》等国际英文SCI期刊审稿人。2013年荣获中南民族大学“十佳青年教工”。目前，主持包括国家自然科学基金项目等6项，在国内外核心期刊发表学术论文36篇，其中被SCI收录27篇。申报中国发明专利1项（公开号：CN**A）。 >

一、代表性研究成果

（一）部分代表性论文（均为SCI收录论文）：

[1] Meijuan Cao, Yuanbin She*, Haiyan Fu*, Yanmin Yu, Hui Li, Tao Wang . Rate-limiting step of the iron porphyrin-catalyzed oxidation of cyclohexane to adipic acid by DFT method, Molecular Simulation, 2014, DOI:10.1080/**.2013.875171.

[2] Tian-Ming Yang, Li-Ping Wang, Hai-Yan Fu*, Yuan-Bin She*, Can Huang, Yan Hu, Hao Zhang. Analysis of phenolic compounds and determination of Loureirin B in Dragon's Blood by LC-MS and HPCE. Asian journal of chemistry. 2014, proof.

[3] Zheng-Lin Zhang, Yuan-Bin She*, Hai-Yan Fu*, Xu-Feng Song, and Zhi-Cheng Sun. An improved synthesis of di-nitro-functionalized trans-a2b2 –tetraphenyl- porphyrins. Heterocycles, 2014, 89(2):503-514.

[4] Jing-Jing Xing, Rui-Min Luo, Hai-Li Guo, Ya-Qiong Li, Hai-Yan Fu, Tian-Ming Yang, Yan-Ping Zhou. Radial basis function network-based transformation for nonlinear partial least-squares as optimized by particle swarm optimization: Application to QSAR studies. Chemometrics and Intelligent Laboratory Systems, 2014, 130:37-44.

[5] Yong-Jie Yu, Hai-Long Wu, Hai-Yan Fu, Juan Zhao, Yuan-Na Li, Shu-Fang Li, Chao Kang, Ru-Qin Yu. Chromatographic background drift correction coupled with parallel factor analysis to resolve coelution problems in three-dimensional chromatographic data: Quantification of eleven antibiotics in tap water samples by high-performance liquid chromatography coupled with a diode array detector. Journal of Chromatography A, 2013, 1302: 72-80.

[6] Hai-Yan Fu, Dong-Chen Huang, Tian-Ming Yang*, Yuan-Bin She*, Hao Zhang. Rapidrecognition of Chinese herbal pieces of Areca catechu by different concocted processes using Fourier transform mid-infrared and near-infrared spectroscopy combined with partial least-squares discriminant analysis, Chinese Chemical Letters, 2013, 24(7): 639-642.

[7] Tian-Ming Yang, Hao Zhang, Hai-Yan Fu*, Yuan-Bin She *, Can Huang, Yan Hu, and Li-Ping Wang, Comparative Studies on the Interaction of Cochinchinenin A and Loureirin B with Bovine Serum Albumin. Journal of spectroscopy, 2013, vol. 2013，Article ID 149615, 9 pages,

[8] Rui-Min Luo, Shi-Miao Tan, Yan-Ping Zhou, Shu-Juan Liu, Hui Xu, Dan-Dan Song, Yan-Fang Cui, Hai-Yan Fu, Tian-Ming Yang. Quantitative analysis of tea using ytterbium-based internal standard near-infrared spectroscopy coupled with boosting leastsquares support vector regression. Journal of Chemometrics, 2013,27(7-8):198-206.

[9] Jin-Fang Nie, Yun Zhang, Zhong-Sheng Yi, Hong-Yan Zou, Hai-Yan Fu, Hai-Long Wu. Advanced chemometric algorithm coupled to subspace projection technique between original and pseudo samples: A snapshot of chemical rank estimation for high-order data. Chemometrics and Intelligent Laboratory Systems. 2012, 118: 211-218.

[10]Hai-Yan Fu, Hai-Long Wu, Yong-Jie Yu, Li-Li Yu, Shu-Rong Zhang, Jin-Fang Nie, Shu-Fang Li, Ru-Qin Yu. A new third-order calibration method with application for four-way data arrays. Journal of Chemometrics, 2011, 25(8): 408-429.

[11]Hai-Yan Fu, Hai-Long Wu, Hong-Yan Zou, Li-Juan Tang, Lu-Xu, Chen Bo-cai, Jin-Fang Nie, Ru-Qin Yu. Automatically Configuring of Optimized Sample -weighted Least-squares Support Vector Machine by Particle Swarm Optimization for Multivariate Spectral Analysis. Analytical Methods, 2010, 2(3): 282-288.

[12]Hai-Yan Fu, Hai-Long Wu, Jin-Fang Nie, Yong-Jie Yu, Hong-Yan Zou, Ru-Qin Yu. Highly sensitive fluorescence determination of irinotecan in biological fluids with the aid of second-order advantage. Chinese Chemical Letters, 2010, 21(12): 1482-1486.

[13]Hai-Yan Fu, Shuang-Yan Huan, Lu Xu, Jian-Hui Jiang, Hai-Long Wu, Guo-Li Shen, Ru-Qin Yu. Construction of an efficacious model for nondestructive identification of traditional Chinese medicines Liuwei Dihuang pills from different manufacturers using near infrared spectroscopy and moving window partial least-squares discriminant analysis. Analytical Sciences, 2009, 25(9): 1143-1148.

[14]Hai-Yan Fu, Shuang-Yan Huan, Lu Xu, Li-Juan Tang, Jian-Hui Jiang, Hai-Long Wu, Guo-Li Shen, Ru-Qin Yu. Moving window partial least-squares discriminant analysis for identification of different kinds of bezoar samples by near infrared spectroscopy and comparison of different pattern recognition methods. Journal of Near Infrared Spectroscopy, 2007,15 (5): 291-297.

[15]Li-Juan Tang, Wen Du, Hai-Yan Fu, Jian-Hui Jiang, Hai-Long Wu, Guo-Li Shen, and Ru-Qin Yu. New Variable Selection Method Using Interval Segmentation Purity with Application to Blockwise Kernel Transform Support Vector Machine Classification of High-Dimensional Microarray Data. Journal of Chemical Information and Modeling, 2009, 49(8): 2002-2009.

[16]Hong-Yan Zou, Hai-Long Wu, Hai-Yan Fu, Li-Juan Tang, Lu Xu, Ru-Qin Yu. Variable-weighted Least-squares Support Vector Machine for Multivariate Spectral Analysis. Talanta, 2010, 80(5): 1698-1701.

[17]Wei-Qi Luo, Shuang-Yan Huan, Hai-Yan Fu, Guo-Li Wen, Hai-Long Wu, Guo-Li Shen, Ru-Qin Yu. Preliminary study on the application of near infrared spectroscopy and pattern recognition methods to classify different types of apple samples. Food Chemistry, 2011, 128(2): 555-561.

[18]Hong-Yan Zou, Hai-Long Wu, Yuan-Na Li, Jin-Fang Nie, Hai-Yan Fu, Shu-Fang Li, Li-Qun Ouyang, Ru-Qin Yu. Simultaneous determination of dextromethorphan and quinidine in biological fluids by excitation-emission matrix fluorescence coupled with second-order calibration methods. Analytical Letters, 2010,43（17）: 2739-2750.

[19]Chen Bo-cai, Lu-Xu, Qing-Juan Han, Hai-Long Wu, Jin-Fang Nie, Hai-Yan Fu, Ru-Qin Yu. Combining the least correlation design, wavelet packet transform and correlation coefficient test to reduce the size of calibration set for NIR quantitative analysis in multi-component systems. Talanta, 2010, 81(3): 799-804.

[20]Shu-Fang Li, Hai-Long Wu, Yong-Jie Yu, Yuan-Na Li, Jin-Fang Nie, Hai-Yan Fu, Ru-Qin Yu. Quantitative analysis of levodopa, carbidopa and methyldopa in human plasma samples using HPLC-DAD combined with second-order calibration based on alternating trilinear decomposition algorithm. Talanta, 2010, 81(3): 805-812.

[21]Yuan-Na Li, Hai-Long Wu, Xiang-Dong Qing, Quan Li, Shu-Fang Li, Hai-Yan Fu, Yong-Jie Yu, Ru-Qin Yu. Quantitative analysis of triazine herbicides in environmental samples by using high performance liquid chromatography and diode array detection combined with second-order calibration based on an alternating penalty trilinear decomposition algorithm. Analytica Chimica Acta, 2010, 678(1): 26-33.

[22]Li-Qun Ouyang, Hai-Long Wu, Jin-Fang Nie, Yan Zhang, Hong-Yan Zou, Hai-Yan Fu, Ru-Qin Yu. Simultaneous determination of psoralen and isopsoralen in plasma and Chinese medicine Xian Ling Gu Bao capsule by using HPLC-DAD coupled with alternating trilinear decomposition algorithm. Analytica Chimica Acta, 2009, 650: 160-166.

[23]Hong-Yan Zou, Hai-Long Wu, Yan Zhang, Shu-Fang Li, Jin-Fang Nie, Hai-Yan Fu, Ru-Qin Yu. Studying the Interaction of Pirarubicin with DNA and Determining Pirarubicin in Human Urine Samples: Combining Excitation -Emission Fluorescence Matrices with Second-order Calibration Methods. Journal of Fluorescence, 2009, 19(6): 955-966.

[24]Hong-Yan Zou, Hai-Long Wu, Li-Qun OuYang, Yan Zhang, Jin-Fang Nie, Hai-Yan Fu, Ru-Qin Yu. Fluorescent quantification of terazosin hydrochloride content in human plasma and tablets using second-order calibration based on both parallel factor analysis and alternating penalty trilinear decomposition. Analytica Chimica Acta, 2009, 650(1): 143-149.

[25]Jin-Fang Nie, Hai-Long Wu, Shao-Hua Zhu, Qing-Juan Han, Hai-Yan Fu, Shu-Fang Li, Ru-Qin Yu. Simultaneous determination of 6-methylcoumarin and 7-methoxycoumarin in cosmetics using three-dimensional excitation–emission matrix fluorescence coupled with second-order calibration methods. Talanta, 2008, 75(5): 1260-1269.

二． 主持的研究项目

[1] 基于高阶校正的民族植物药多组分体内协同代谢动力学过程多维定量表征研究(No. **)，国家自然科学基金青年项目（2013年），项目负责人。

[2] 中药材资源近红外光谱专属性模式识别模型判别分析质量控制技术(No.2011BMZ087)，湖北省技术转移项目，科学技术厅（2012年）， 立项，合作单位项目负责人。

[3] 民族药物活性组分体内代谢动力学过程多维表征及高阶校正量化研究(No.201111), 化学生物传感与计量学国家重点实验室开放基金（2012年），项目负责人。

[4] 中药材资源近红外光谱专属性模式识别模型判别分析质量控制技术（No. HZY11062)，企业横向项目(2011年)，项目负责人。

[5] 藏药麻花秦艽活性成分体内代谢动力学过程多维定量表征(No. CZQ11012)，中南民族大学中央高校专项基金（2011年），项目负责人。

[6] 药物分析案例教学模式探索研究与实践(No. JYX11015),中南民族大学教改项目（2011年），项目负责人。