出生年月：1982年2月

民 族：汉

职 称：讲师

学科专业：药物化学

研究方向：抗肿瘤小分子活性化合物的设计与合成

电 话：**

电子邮箱：wqwq0209@yahoo.com.cn

简 历：

2004年毕业于武汉大学药学院，获医学学士学位；

2009年毕业于山东大学药学院，药物化学专业，获医学博士学位；

2010年至今，工作于中南民族大学药学院。

一、研究方向：

抗肿瘤药物的设计与合成；计算机辅助药物设计。

二、发明专利：

碱性氨基酸类金属蛋白酶抑制剂及其应用，公开号：CN ** A

三、发表的研究论文：

1. Qiang Wang, Maoying Chen, Huawei Zhu, Jie Zhang, Hao Fang, Binghe Wang, Wenfang Xu. Design, synthesis and QSAR studies of novel Lysine derives as aminopeptidase N /CD13 inhibitors. Biorg. Med. Chem.2008, 16, 5473-5481.

2. Qiang Wang,Fuming Xu, JiajiaMou,Jian Zhang, Luqing Shang, Yepeng Luan, Yumei Yuan, Yingzi Liu, Minyong Li, Hao Fang, BingheWang,WenfangXu. Design, synthesis and primary activity evaluation of novel L-lysine derivates as aminopeptidase N/CD13 inhibitors. Protein Pept. Lett.2010;17(7):847-53.

3. Jing Su, Qiang Wang, Jinhong Feng, Cong Zhang, Deyu Zhu, Tiandi Wei, Wenfang Xu, Lichuan Gu. EngineeredThermoplasmaacidophilum factor F3 mimics human aminopeptidase N (APN) as atarget for anticancer drug development. Bioorg Med Chem.2011,19(9):2991-6.

4. Jie Zhang, Qiang Wang, Hao Fang, Wenfang Xu, Ailin Liu, Guanhua Du. Design,synthesis,inhibitory activity and SAR studies of hydrophobic p-aminosalicylic acid derivatives as neuraminidase inhibitors.Biorg. Med. Chem. 2008,16, 3839-3847.

5. Kanghui Yang,Qiang Wang, Li Su, Hao Fang, Xuejian Wang, Jianzhi Gong, Binghe Wang, WenfangXuDesign and synthesis of novel chloramphenicol amine derivatives as potent aminopeptidase N (APN/CD13) inhibitors. Biorg. Med. Chem.2009,17, 3810-3817.

6. Xian-Chao Cheng, Qiang Wang, HaoFang, Wei Tang, Wen-Fang Xu. .Biorg. Med. Chem.2008,16, 7932-7938.

7. Xian-Chao Cheng, Qiang Wang, Hao Fang, Wei Tang, Wen-Fang Xu. .Biorg. Med. Chem.2008,16, 5398-5404.

8. Jie Zhang, Qiang Wang, Hao Fang, Wenfang Xu, Ailin Liu, Guanhua Du. .Biorg. Med. Chem.2007, 15, 2749-2758.

9. Luqing Shang, Qiang Wang, Hao Fang, Jiajia Mu, Xuejian Wang, Yumei Yuan, Binghe Wang, WenfangXu. . Biorg. Med. Chem.2008, 16, 9984-9990.

10. Xian-Chao Cheng, Qiang Wang, HaoFang, Wei Tang, Wen-Fang Xu. .Eur. J. Med. Chem. 2008,43, 2130-2139.

11. Xian-Chao Cheng, Qiang Wang, HaoFang, Wen-Fang Xu. Role of Sulfonamide Group in Matrix Metalloproteinase Inhibitors. Curr. Med. Chem.2008,15, 368-373.

12. Xian-Chao Cheng, Qiang Wang, HaoFang, Wen-Fang Xu. Advances in Matrix Metalloproteinase Inhibitors Based on Pyrrolidine Scaffold.Curr. Med. Chem. 2008,15, 374-385.

13. Jie Jiao, Qiang Wang, Hua Wei Zhu, Hao Fang, Wen Fang Xu. .Chin. Chem. Lett.2008,19, 673-675.