姓 名：陈祖兴，

出生年月：1955,3

职称职务：教授

专业方向：有机化学

办公电话：**

Email：　chzux@hubu.edu.cn



研究领域与兴趣：

聚合物支载合成及组合化学；生物活性物质的合成；精细化学品



教育与研究经历：



教学情况：

主讲研究生《金属与元素有机化学》



承担项目与课题：

1、新型聚合物微球支载手性诱导试剂的设计、合成及其应用研究（**），国家自然科学基金，项目负责人。

2、新型功能化聚合物微球的设计制备及其支载化有机合成研究（**），国家自然科学基金，项目负责人。

3、可溶性聚合物支载手性试剂制备及应用研究(**)，国家自然科学基金，项目负责人。

4、有机磷精细化学品研发，湖北兴发化工集团股份有限公司，300.00 万，项目负责人。

5、昆虫信息素的高立体选择性合成及其应用研究(2008CDA078)，湖北省科技攻关，项目负责人。

6、丙烯酸N－烷基全氟辛基磺酰氨基乙酯中试工艺研究(2003AA101C96)，湖北省科技攻关，项目负责人。

7、氟化丙烯酸酯单体及其聚合物基料乳液的合成研究, 湖北省科技攻关，项目负责人。

8、精细化学品研发，武汉银冠化工有限公司，2008~2012, 100万元，项目负责人。

9、全氟烷基酸脂的中试生产工艺及光纤包材开发研究（**）武汉市科技攻关，项目负责人。

10、新型支载化手性诱导试剂的合成及其应用研究(**),国家自然科学基金，（第二）。



获奖与荣誉：

1、 “支载化有机合成研究” 获湖北省2007年度自然科学叁等奖（第一）。

2、 “生物活性物质的高立体选择性合成”获湖北省2001年度自然科学叁等奖（第一）
代表性成果：

近期获得授权发明专利：

1、陈祖兴, 李甲, 杨桂春, 卢翠芬. 线型聚苯乙烯支载手性噁唑烷-2-硒酮及其制备方法.，ZL **0.7.

2、卢翠芬, 陈祖兴, 夏德新, 胡富强, 杨桂春. 线型聚苯乙烯支载(4S)-噁唑烷-2-苯亚胺及其制备方法和用途. ZL：**8.9.

3、万亚东;陈祖兴;杨桂春;卢翠芬线型聚苯乙烯支载的(4S)-5,5-二取代基噁唑烷酮及其制备方法和用途，ZL **0.9

近期发表的论文：

1、Lu, C.F., Hu, L., Yang, G.C., Chen, Z. X. 2-Imidazolidinones as Chiral Auxiliaries in Asymmetric Synthesis, Current Organic Chemistry,2012,16, 2802-2817.

2、Lu, C.F., Zhang, L.D., Su, H., Yang, G.C., Chen, Z.X. Asymmetric synthesis of both (R)- and (S)-arundic acid , Journal of Chemical Research,2012,11, 678-679

3、Li, XR ., Lu, C.F., Chen, Z.X., Li, Y., Yang, G.C. Asymmetric and diastereoselective Mannich reactions using hydantoin as a chiral auxiliary, Tetrahedron-Asymmetry,2012, 23, 1380-1384

4、Deng, J., Lu, C.F., Hu, L., Yang, G.C., Chen, Z.X. Preparation of microgel-supported chiral catalysts and their application in the asymmetric hydrogenation of aromatic ketones, Reactive & Functional Polymers, 2012, 72, 378-382

5、Zhang, J.S ., L.U, CF., Chen, Z.X., Li, Y., Yang G.C. Boron Enolates of A Hydantoin Chiral Auxiliary Derived From L-Phenylalanine: A Versatile Tool for Asymmetric Aldol Reactions，Tetrahedron-Asymmetry, 2012, 23(1) :72-75.

6、Feng, C., Wang Q.,Y Lu C. F., Yang G.C.., Chen Z.X. Green Synthesis of Tetrahydrobenzo[B]Pyrans by Microwave Assisted Multi-Component One-Pot Reactions in PEG-400, Combinatorial Chemistry & High Throughput Screening, 2012, 15(1):100-103

7、He X.P., Lu C.F., Chen Z.X., Yang G.C. Synthesis of A New Chiral Auxiliary Non -Cross-Linked Polystyrene-Supported Oxazolidine-2-Selone, Can. J. Chem., 2011, 89, 88-91.

8、Gao M., Lu C.F., Yang G.C., Chen Z.X. A Novel Approach For Synthesis of 3- Amino-5-Aryl-2,5- Dihydropyridazines using Onium Salt as Soluble Support, Chinese Chemical Letters, 2011, 22, 823-826.

9、Zhang L., Lu C.F., Yang G.C., Chen Z.X. Novel Synthesis of 2-Amino -3- Ethoxycarbonyl Benzopyrans with Onium Salt as Soluble Support, Chem. Res. Chinese U., 2011, 27, 435-440.

10、Zhao P., Lu C.F., Yang G.C., Chen Z.X., Dong N.G., Shi J.W. Stereoselective Synthesis of Polysubstituted Cyclopropanes From Poly(Ethylene Glycol) Supported Pyridinium Ylide, Chem. Res. Chinese U., 2011, 27, 984-987.

11、Hu F.Q., Xia D.X., Lu C.F., Chen Z.X., Yang G.C. A New Non-Cross-Linked Polystyrene Supported 2-Phenylimino-2-Oxazolidine Chiral Auxiliary: Synthesis And Application in Asymmetric Alkylation Reactions. Eur. J. Org. Chem., 2010, 5552-5554.（Highlighted In Synfacts 2011, 117）

12、Lu C.F., Zhang L., Yang G.C, Chen Z.X. Task Specific Onium Salt as Soluble Support in Multicomponent Synthesis of 4-Aryl-2-Amino-3- Ethoxycarbonyl- Naphthopyrans. Chin. J. Chem., 2010, 28, 2469-2473.

13、Xia D.X., Feng C., Lu C.F., Chen Z.X., Yang G.C. New Practical Synthesis of Tetrahydronquinolin- 2,5-Diones. Chem. Res. Chinese U., 2010, 26, 749-752.

14、Feng C., Lu C.F., Chen Z.X., Dong N.G., Shi J.W., And Yang G.C. A Facile Synthesis of Tetrasubstituted 2,3-Dihydrofuran Derivatives using Poly(Ethylene glycol) as Soluble Support. J. Heterocyclic Chem., 2010, 47, 671-676.

15、Zhou F.Y., Lu C.F., Chen Z.X. And Yang G.C. Stereoselective Synthesis of an Alarm Pheromone of Grematogaster Arts Using (S)-4-Benzyloxazolidinone as Chiral Auxiliary. Chem. Nat. Compd., 2010, 46, 83-85.

16、Li J., Lu C.F., Chen Z.X., Yang G.C. Synthesis of Non-Crossed-Linked Polystyrene Supported (4S)-4- Substituted-4,5-Dihydrooxazoline. J.Chem.Res-S, 2010, 86-87.

17、Li D.L., Lu C.F., Yang G.C., And Chen Z.X. Stereoselective Synthesis of Sex Pheromone of The Yellow Mealworm using (S)-4-Benzyloxazolidinone as Chiral Auxiliary. Chem. Nat. Compd., 2010, 46, 440-443.

18、Lu C.F., Li D.L., Wang Q.Y., Yang G.C., Chen Z.X. Stereoselective Synthesis of Sex Pheromone (R)-4-Methyl-1-Nonanol: Non-Cross-Linked Polystyrene Supported Oxazolidinone as A Chiral Auxiliary，Eur. J. Org. Chem. 2009, 1078-1081.

19、Lu C.F., Zhang S.B., Li Y., Yang G.C., Chen Z.X. Stereoselective Synthesis of (R)-10- Methyltridecan -2-One, The Sex Pheromone of the Southerncorn Root worm, using (4S)-Benzylthiazolidinethione As A Chiral Auxiliary, Tetrahedron: Asymmetry,2009, 20, 2267-2269.

20、Lu C.F., Nie J.Q., Yang G.C., Chen Z.X. An Improved Synthesis of Sitophilure，Can. J. Chem., 2009，87, 30-32.

21、Xie, H.W., Lu C.F., Yang G.C., Chen Z.X. Synthesis of 1,4-Benzodia zepine-2,5-Diones using An Ionic Liquid as A Soluble Support, Synthesis, 2009, 205-210.

22、Lu C.F., Xie C., Chen Z.X., Yang G.C. Synthesis of New Soluble Dendrimers on Poly(Ethylene Glycole) Sublayer, Russ. J. Org. Chem., 2009, 45, 788 -791.

23、Yang J.H., Yang G.C., Lu C.F., Chen Z.X. Asymmetric Synthesis of (2R, 5S)-2- Methyl-5-Hexanolide, The Sex Pheromone of Carpenter Bee Xylocopa Hirutissima, Tetrahedron- Asymmetry,2008, 19, 2164-2166.

24、Huang Y.L., Lu C.F., Chen Z.X., Yang GC. Traceless Synthesis of Quinazoline- 2,4-Diones By Curtius Rearrangement Reaction Using Poly(Ethylene Glycol) as Soluble-Polymeric Support, Journal of Heterocyclic Chemistry, 2007, 44, 1421-1424.

25、Yan X.Q., Yu J.J., Ye R.H., Chen Z.X., Yang GC. Synthesis of a Library of N-Substituted Methyl Aminocarbonyl Acetates using Poly(Ethylene Glycol) as Soluble Support, Letters in Organic Chemistry, 2007, 4 , 239-241.

26、Peng H.D., Huang Y.L., Yang J.H., Chen Z.X., Yang GC. Traceless Synthesis of 3-N-Substituted -2-Thioxoquinazoline-4-Ones on A Soluble Polymeric Support, Combinatorial Chemistry & High Throughpu Screening, 2007, 10 , 257-260.

27、Chen J.N., Yang G.C., Zhang H.Q., Chen ZX. Non-Cross-Linked Polystyrene Bound Reagents, Catalysts and Syntheses, Reactive & Functional Polymers, 2006, 66, 1434-1451.

28、Yang G.C., Zhang H.Q., Huang Y.L., Chen Z.X. Synthesis of Methyl N-Aryl Oxamate using Soluble Polymer Support，Synthetic Communications, 2006, 36, 611-619.

29、Zhang H.Q., Yang G.C., Chen J.N., Chen Z.X. Synthesis of Thiophene Derivatives on Soluble Polymer-Support using Gewald Reaction, Synthesis, 2004, 18, 3055-3059.

30、Yang G.C., Chen Z.X., Zhang H.Q. Clean Synthesis of An Array of N-Benzoyl–N’-Aryl Ureas using Polymer-Supported Reagents, Green Chemistry, 2003, 5, 441-442.


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