向东山个人简介
博士，教授，硕士研究生导师
研究方向：分子光谱分析
Email: zk3100@sohu.com
教育与研究经历
2005.7-至今，湖北民族大学，任教
2009.9-2012.7，武汉大学，分析化学，获得博士学位
2002.9-2005.7，贵州大学，植物营养学，获得硕士学位
1993.9-1996.7，湖北民族学院，化工工艺
主持科研项目
(1) 国家自然科学基金，超猝灭多功能分子信标的构建及应用研究
(2) 国家民委教学研究项目，新工科建设背景下地方民族院校环境类专业应用型人才培养模式改革研究
主要代表性成果
2 期刊论文：
2 (1) D. S. Xiang, G. P. Zeng, Z. K. He*. Magnetic microparticle-based multiplexed DNA detection with biobarcoded quantum dot probes. Biosens & Bioelectron, 2011, 26(11):4405-4410
2 (2) D. S. Xiang*, K. Zhai, L. Z. Wang. Multiplexed DNA detection with a composite molecular beacon based on guanine-quenching. Analyst, 2013, 138(18):5318-5324
2 (3) D. S. Xiang, G. H. Zhou, M. Luo, X. H. Ji, Z. K. He*. Dual color fluorescence quantitative detection of specific single-stranded DNA with molecular beacons and nucleic acid dye SYBR Green I. Analyst, 2012, 137(16):3787-3793
2 (4) D. S. Xiang, Zhang CL, L. Chen, X. H. Ji, Z. K. He*. Tricolour fluorescence detection of sequence-specific DNA with a new molecular beacon and a nucleic acid dye TOTO-3. Analyst, 2012, 137(24):5898-5905
2 (5) D. S. Xiang, Zheng AH, Luo M, Ji XH, Z. K. He*. Graphene oxide and molecular beacons-based multiplexed DNA detection by synchronous fluorescence analysis. Sci China Chem, 2013, 56(3):380-386
2 (6) D. S. Xiang, Zeng GP, Zhai K, Li L, Z. K. He*. Determination of melamine in milk powder based on the fluorescence enhancement of Au nanoparticles. Analyst, 2011, 136(13):2837-2844
2 (7) D. S. Xiang, K. Zhai, W. J. Xiang, L. Z. Wang. Highly sensitive fluorescence quantitative detection of specific DNA sequences with molecular beacons and nucleic acid dye SYBR Green I. Tlanta, 2014, 129:249-253
2 (8) 向东山，史伯安，翟琨，王联芝．利用无标记的分子信标有核酸染料检测乙肝病毒．中国科学：化学，2014, 44(12) :1996-2003
2 (9) Z. J. Lu, Y. S. Jiang, P. Wang, W. W. Xiong, B. P. Qi, Y. K. Zhang, D. S. Xiang*, K. Zhai*. Bimetallic Organic Framework-based aptamer sensors：a new platform for fluorescence detection of chloramphenicol [J], Anal. Bioanal. Chem., 2020, 412(22):5273~5281.
2 (10) D. S. Xiang, F. Q. Li, C. Y. Wu, B. A. Shi, K. Zhai*. The G-BHQ synergistic effect Improved double quenching molecular beacons based on guanine and Black Hole Quencher for sensitive simultaneous detection of two DNAs [J], Talanta, 2017, 174: 289~294.
2 (11) D. S. Xiang*, K. Zhai, Q. Z. Sang, B. A. Shi, X. H. Yang. Highly Sensitive Fluorescence Quantitative Detection of Mercury in Soil Based on Non-labeled Molecular Beacon and Fluorescent Dye Hoechst 33258 [J], Anal. Sci., 2017, 33(3): 275~279.
2 (12) Z. J. Lu, W. W. Xiong, P. Wang, X. Li, K. Zhai, R. J. Shi*, D. S. Xiang*. Simultaneous detection of lead (II) and mercury (II) ions using nucleic acid aptamer molecular beacons [J]. Int. J. Environ. An. Ch., 2019, Publish online, DOI: 10.1080/**.2019.**.
2 (13) Z. J. Lu, P. Wang, W. W. Xiong, B. P. Qi, R. J. Shi, D. S. Xiang*, K. Zhai*. Simultaneous detection of mercury (II), lead (II) and silver (I) based on fluorescently labeled nucleic acids and graphene oxide [J]. Environ. Technol., 2020, Publish online, DOI: 10.1080/**.2020. **.
2 (14) 熊威威，张应坤，鲁子敬，汪鹏，翟琨*，向东山*．基于双荧光基团分子信标对水体中铅离子(Ⅱ)的双色荧光定量检测[J]，农业环境科学学报，2020 , 39(12) : 2895-290.
2 (15) 翟 琨，李奉权，史伯安，向东山*．基于双重猝灭原理的分子信标定量检测凝血酶[J]，分析化学, 2017, 45(10): 1462~1466.
2 (16) 鲁子敬，熊威威，翟 琨，向东山*，谭志斗*．基于双重猝灭分子信标及核酸染料Hoechst 33258对单链核酸的双色定量检测[J]，分析化学，2019, 47 (7): 1014-1020.
2 (17) 向东山*．利用无标记分子信标及核酸染料TOTO-3检测转基因食品[J]，食品科学，2014, 36(2): 174~178.
2 奖励
2 （1）郑小江，刘金龙，向东山，向班贵，罗世家，张升晖，周大寨，汪建敏，刘晓鹏，肖强，李玉山，武芸，朱玉昌，唐巧玉，王柏权。藤茶品种选育及开发利用（奖证编号：2009J-208-2-072-008-R03），湖北省科技厅，省科技进步奖，二等奖，2009。
2 （2）Xiang DS, Zeng GP, He ZK. Magnetic microparticle-based multiplexed DNA detection with biobarcoded quantum dot probes，湖北省科学技术协会，湖北省人力资源和社会保障厅，湖北省科技厅，湖北省自然科学优秀学术论文奖，二等奖，2012。
2 发明专利
一种基于Cu/UiO-66金属有机框架猝灭的同步荧光检测氯霉素的方法（实质审查）