1986年9月-1990年7月 华中农业大学 学士学位
1990年9月-1993年7月 华中农业大学 硕士学位
1993年9月-1996年7月 华东师范大学 博士学位
工作经历：
1996年7月-1998年8月 中国科学院水生生物研究所 博士后
1998年9月-今 华中师范大学生命科学学院，副教授、教授
2001年7月-2003年8月 法国巴黎居里研究所 博士后
2005年12月-2006年5月 澳大利亚昆士兰大学 访问****；
主要研究领域：
1．动物（果蝇、鱼、虾）生殖与发育的分子调控机制；
2．水生经济动物（鱼、虾）增养殖学。
承担科研项目：
1. 国家自然科学基金项目（**）：ocnus调控果蝇雄性生殖细胞发生的机制研究，2019.1- 2022.12，主持。
2. 国家自然科学基金项目（**）：Wolbachia对果蝇雄性生殖系统先天免疫的影响及其与生殖的关系，2017.1- 2020.12，主持。
3. 国家自然科学基金项目（**）：基于精子蛋白组学研究Wolbachia诱导果蝇CI的分子机制，2012.1- 2015.12，主持。
4. 国家自然科学基金项目（**）：Wolbachia感染对果蝇精子育性的影响，2010.1- 2012.12，主持。
5. 国家自然科学基金项目（**）：雌核发育银鲫 Hira 基因的克隆及其功能分析，2007.1 - 2009.12, 主持。
6. 国家自然科学基金项目（**）：用功能获得性方法鉴定果蝇胚胎中囊胚过渡的调控因子，2004.1-2006.12，主持。
7. 湖北省对外科技合作项目（2017AHB050）：沃尔巴克氏体感染对果蝇学习记忆能力的影响及对害虫防治和生态环境的作用，2018.1—2019.12，主持。
8. 武汉市学科带头人计划项目（4）：克氏原螯虾健康养殖技术研究，2011.1-2013.12，主持。
代表性论文：
1. Bi J, Zheng Y, Rui-Fang Wang, Hui Ai, Paula R. Haynes, Jeremy C. Brownlie, Xiao-Qiang Yu, Wang YF*. Wolbachia infection may improve learning and memory capacity of Drosophila by altering host gene expression through miRNA. Insect Biochemistry and Molecular Biology, 2019，106：47–54.
2. Biwot JC, Zhang HB, Liu C, Qiao JX, Yu XQ, Wang YF*. Wolbachia-induced expression of kenny gene in testes affects male fertility in Drosophila melanogaster. Insect Science, 2019, doi: 10.1111/1744-7917.12730.
3. Bi J, Wang YF*.The effect of the endosymbiont Wolbachia on the behavior of insect hosts. Insect Science, 2019, DOI:10.1111/1744-7917.12731.
4. Zhen He, Ya Zheng, Wen-Juan Yu, Yang Fang, Bin Mao, Wang YF*. How do Wolbachia modify the Drosophila ovary? New insights into mechanisms of Wolbachia dependence on female hosts. BMC Genomics, 2019, 20: 608.
5. Zheng Y, Shen W, Bi J, Chen MY, Wang RF, Ai H, Wang YF*. Small RNA analysis provides new insights into cytoplasmic incompatibility in Drosophila melanogaster induced by Wolbachia. Journal of Insect Physiology, 2019, 103938.
6. Zheng Y, Bi J, Hou MY, Shen W, Zhang W, Ai H, Yu XQ, Wang YF*. 2018. Ocnus is essential for male germ cell development in Drosophila. Insect Molecular Biology, 27(5): 545-555.
7. Bi J, Sehgal A, Williams J. A., Wang YF*. 2018. Wolbachia affects sleep behavior in Drosophila melanogaster. Journal of Insect Physiology, 107: 81-88.
8. Tan HY, Shao GM, Kang PF, Wang YF*. 2017. Full-length normalization subtractive hybridization analysis provides new insights into sexual precocity and ovarian development of red swamp crayfish Procambarus clarkii. Aquaculture, 468: 417-427.
9. 张维，郑雅，王玉凤*. 沃尔巴克氏体感染对果蝇性腺和早期胚胎DNA 6mA去甲基化酶基因DMAD表达的影响. 昆虫学报，2017，60(11): 1292－1299.
10. Wu CH, Zong Q, Du AL, Zhang W, Yao HC, Yu XQ, Wang YF*. 2016. Knockdown of Dynamitin in testes significantly decreased male fertility in Drosophila melanogaster. Developmental Biology, 420: 79-89.
11. Yuan LL, Chen X, Zong Q, Zhao T, Wang JL, Zheng Y, Zhang M, Wang Z, Brownlie JC, Yang F*, Wang YF*. 2015. Quantitative proteomic analyses of molecular mechanisms associated with cytoplasmic incompatibility in Drosophila melanogaster induced by Wolbachia. Journal of Proteome Research, 14: 3835-3847.
12. Liu C, Wang J, Zheng Y, Xiong EJ, Li JJ, Yuan LL, Yu XQ, Wang YF*. 2014. Wolbachia-induced paternal defect in Drosophila is likely by interaction with the juvenile hormone pathway. Insect Biochemistry and Molecular Biology, 49：49-58.
13. Xia XF, Zheng JJ, Shao GM, Wang JL, Liu XS, Wang YF*. 2013. Cloning and functional analysis of glutathione peroxidase gene in red swamp crayfish Procambarus clarkii. Fish & Shellfish Immunology, 34: 1587-1595.
14. Zheng Y, Wang JL, Liu C, Wang CP, Walker T, Wang YF*. 2011. Differentially expressed profiles in the larval testes of Wolbachia infected and uninfected Drosophila. BMC Genomics, 12:595.
15. Zheng Y, Ren PP, Wang JL, Wang YF*. 2011. Wolbachia-induced cytoplasmic incompatibility is associated with decreased Hira expression in male Drosophila. PLoS One, 6（4）：e19512
16. Zhao ZK, Li W, Wang MY, Zhou L, Wang JL, Wang YF*. 2011. The role of HIRA and maternal histones in sperm nucleus decondensation in the gibel carp and color crucian carp. Molecular reproduction and development, 78(2):139-147.
17. 王玉凤（主编）. 发育生物学。北京：科学出版社，2011
18. 郭秋红，赵占克，王玉凤*，桂建芳. 2010. Hira基因产物在银鲫和彩鲫卵子发生过程中的动态变化. 水生生物学报， 34（3）：611-617
19. 彭宇，王玉凤*. 2009. Wolbachia感染显著提高果蝇嗅觉反应. 科学通报， 54: 596 - 602.
20. McMeniman CJ, Lane RV, Cass BN, Fong AWC, Sidhu M, Wang YF, O’Neill SL. 2009. The stable introduction of a life-shortening Wolbachia infection into the mosquito Aedes aegypti. Science, 323, 141-144.
（*通讯作者）
学术兼职:
1．中国动物学会理事
2. 湖北省动物学会副理事长
3. 湖北省水产学会常务理事
---------------------------------------
Wang, Yu-Feng
Title：
Professor
Office Address：
5-305
Lab Address：
5-306
E-mail：
yfengw(AT)mail.ccnu.edu.cn
Resume:
Sep. 1998.8-present: Associate professor, Professor, School of Life Sciences, Central China Normal University.
Dec. 2005-May, 2006: Academic visitor, School of Integrative Biology, The University of Queensland, Brisbane QLD 4072,
July, 2001-Aug. 2003: Post-doctor, UMR218, CNRs, Curie Institute-Section of Research, 75248 Paris,
July, 1996-Aug. 1998: Post-doctor, Institute of Hydrobiology, Chinese Academy of Sciences;
Sep. 1993-July, 1996: Ph.D., Dept. of Biology, East China Normal University;
Sep. 1990-July, 1993: M.Sc., Dept. of Fisheries, Huazhong Agricultural University;
Sep. 1986.9-July, 1990: B.Sc., Dept. of Fisheries, Huazhong Agricultural University.
Research Interestes:
1. Molecular regulatory mechanisms of reproduction and development in animals (Drosophila, fishes, shrimp);
2. Aquaculture technology of fishes and shrimps.
Research Grants：
1. National Nature Science Foundation of China（**）：Mechanisms of ocnus regulating male germ cell development in Drosophila. 2019.1- 2022.12.
2. National Nature Science Foundation of China（No.: **）：Effects of Wolbachia on innate immunity of reproductive system of Drosophila melanogaster and its association with reproduction. 2017- 2020.
3. National Nature Science Foundation of China (No.: **) : Molecular mechanism of CI induced by Wolbachia in Drosophila based on sperm proteomics. 2012-2015.
4. National Nature Science Foundation of China (No.: **) : Effect of Wolbachia infection on the fecundity of Drosophila. 2010-2012.
5. National Nature Science Foundation of China (No.: **): Cloning and functional analysis of Hira gene in gynogenetic gibel carp. 2007-2009
6. National Nature Science Foundation of China (No.: **): Identification of the factors involved in the regulation of mid-blastula-transition in Drosophila by gain-of-function. 2004-2006.
7. Key projects of science and technology of ministry of education of China（109118）：Study on the molecular mechanism of Wolbachia-induced CI in Drosophila melanogaster from the point of view of gene differential expression during spermatogenesis. 2009-2011.
8. The International Cooperation Projects of Science and Technology of Hubei Province (2017AHB050)：Effect of Wolbachia infection on learning and memory ability of Drosophila and its effects on pest control and environment. 2018-2019.
9. Program for academic leader in Wuhan city (4)：Research on healthy breeding technology in the crayfish (Procambarus clarkii)
Representative Peer-reviewed Publications:
1. Bi J, Zheng Y, Rui-Fang Wang, Hui Ai, Paula R. Haynes, Jeremy C. Brownlie, Xiao-Qiang Yu, Wang YF*. Wolbachia infection may improve learning and memory capacity of Drosophila by altering host gene expression through miRNA. Insect Biochemistry and Molecular Biology, 2019，106：47–54.
2. Biwot JC, Zhang HB, Liu C, Qiao JX, Yu XQ, Wang YF*. Wolbachia-induced expression of kenny gene in testes affects male fertility in Drosophila melanogaster. Insect Science, 2019, doi: 10.1111/1744-7917.12730.
3. Bi J, Wang YF*.The effect of the endosymbiont Wolbachia on the behavior of insect hosts. Insect Science, 2019, DOI:10.1111/1744-7917.12731.
4. Zhen He, Ya Zheng, Wen-Juan Yu, Yang Fang, Bin Mao, Wang YF*. How do Wolbachia modify the Drosophila ovary? New insights into mechanisms of Wolbachia dependence on female hosts. BMC Genomics, 2019, 20: 608.
5. Zheng Y, Shen W, Bi J, Chen MY, Wang RF, Ai H, Wang YF*. Small RNA analysis provides new insights into cytoplasmic incompatibility in Drosophila melanogaster induced by Wolbachia. Journal of Insect Physiology, 2019, 103938.
6. Zheng Y, Bi J, Hou MY, Shen W, Zhang W, Ai H, Yu XQ, Wang YF*. 2018. Ocnus is essential for male germ cell development in Drosophila. Insect Molecular Biology, 27(5): 545-555.
7. Bi J, Sehgal A, Williams J. A., Wang YF*. 2018. Wolbachia affects sleep behavior in Drosophila melanogaster. Journal of Insect Physiology, 107: 81-88.
9. Tan HY, Shao GM, Kang PF, Wang YF*. 2017. Full-length normalization subtractive hybridization analysis provides new insights into sexual precocity and ovarian development of red swamp crayfish Procambarus clarkii. Aquaculture, 468: 417-427.
10. Wu CH, Zong Q, Du AL, Zhang W, Yao HC, Yu XQ, Wang YF*. 2016. Knockdown of Dynamitin in testes significantly decreased male fertility in Drosophila melanogaster. Developmental Biology, 420: 79-89.
11. Yuan LL, Chen X, Zong Q, Zhao T, Wang JL, Zheng Y, Zhang M, Wang Z, Brownlie JC, Yang F*, Wang YF*. 2015. Quantitative proteomic analyses of molecular mechanisms associated with cytoplasmic incompatibility in Drosophila melanogaster induced by Wolbachia. Journal of Proteome Research, 14: 3835-3847.
12. Liu C, Wang J, Zheng Y, Xiong EJ, Li JJ, Yuan LL, Yu XQ, Wang YF*. 2014. Wolbachia-induced paternal defect in Drosophila is likely by interaction with the juvenile hormone pathway. Insect Biochemistry and Molecular Biology, 49：49-58.
13. Wang MY, Guo QH, Du XZ, Zhou L, Luo Q, Zeng QH, Wang JL, Zhao HB, Wang YF*. 2014. HIRA is essential for the development of gibel carp. Fish physiology and biochemistry, 40:235-244.
14. Wang CP, Zheng Y, Zheng JJ, Wang YF*. 2014. Paternal effects caused by the knockdown of Mst84Db mimic cytoplasmic incompatibility induced by Wolbachia in Drosophila melanogaster. Acta Entomologica Sinic， 57(3): 293-299.
15. Xia XF, Zheng JJ, Shao GM, Wang JL, Liu XS, Wang YF*. 2013. Cloning and functional analysis of glutathione peroxidase gene in red swamp crayfish Procambarus clarkii. Fish & Shellfish Immunology, 34: 1587-1595.
16. Zheng Y, Wang JL, Liu C, Wang CP, Walker T, Wang YF*. 2011. Differentially expressed profiles in the larval testes of Wolbachia infected and uninfected Drosophila. BMC Genomics, 12:595.
17. Zheng Y, Ren PP, Wang JL, Wang YF*. 2011. Wolbachia-induced cytoplasmic incompatibility is associated with decreased Hira expression in male Drosophila. PLoS One, 6（4）：e19512
19. Wang YF（chief editor）. Developmental Biology. Beijing：Science Press，2011
20. McMeniman CJ, Lane RV, Cass BN, Fong AWC, Sidhu M, Wang YF, O’Neill SL. 2009. The stable introduction of a life-shortening Wolbachia infection into the mosquito Aedes aegypti. Science, 323, 141-144.
（*Corresponding author）
