教育经历：
1987年9月- 1991年7月 湖北大学 学士学位
2002年9月- 2007年6月 武汉大学 博士学位
工作经历：
2007年7月至今 华中师范大学，生命科学学院，讲师，副教授
2014年3月 – 2015年3月：美国匹兹堡大学，医学院，访问****
1991年7月- 2002年8月 武钢程潮铁矿子弟中学 教师
荣誉或奖励
2016年6月 湖北省科学技术进步奖二等奖
2018年1月 2017年度英国皇家化学学会杰出评审专家
主要研究领域：
环境污染物对人体健康的影响 -
承担科研项目：
1. 国家重点研发计划 "建筑室内空气质量运维共性关键技术研究"（课题编号：2017YFC**）子课题，2017年6月-2020年6月，主持
2. 国家重点研发计划委托课题，"基于热舒适评价的人体生理参数指标测试研究"，8万元。2017年6月-2018年6月，主持
3.中央高校科研业务费2017年重大交叉研究项目，CCNU17ZDJC05，建筑室内过敏性疾病的健康风险和致病机理研究，主持
4. 国家自然科学基金青年项目（**）：增塑剂邻苯二甲酸酯对大鼠甲状腺内分泌干扰作用及其机理的研究，2016.1-2018.12, 参加。
5. 国家科技支撑计划子课题（2012BAJ02B03）：建筑室内半挥发有机物（SVOC）及其复合污染检测及控制关键技术研究，2012.1-2016.12，参加
6. 国家科技支撑计划（2012BAJ02B06，建筑室内空气污染监测及运营管理技术研究）子课题：不同典型污染物浓度水平下的动物实验研究，2015.9-2016.10，主持
7. 国家科技支撑计划（2012 BAJ02B05-1，西部内陆地区室内环境对人体健康的影响及评估）子课题：实验室环境中不同温湿度及污染物浓度条件下的动物实验测试，2015.1-2015.12，主持
8. 国家自然科学基金面上项目（**）：室内典型SVOC散发、传播机理及体内暴露研究，2011.1-2013.12，参加。
9. 湖北省自然科学基金（2008CBD107）： EV71病毒衣壳蛋白与宿主细胞内源蛋白相互作用研究，2009.1-2010.12, 主持。
代表性论文：
1. Duan JF, Kang J, Deng T, Yang X, Chen MQ*. 2018. Exposure to DBP and High Iodine Aggravates Autoimmune Thyroid Disease Through Increasing the Levels of IL-17 and Thyroid-Binding Globulin in Wistar Rats. Toxicological Sciences, 163(1):196–205.
2. Kang J, Duan JF, Song J, Luo C, Liu H, Li BZ, Yang X, Yu W*, Chen MQ*. 2018. Exposure to a Combination of Formaldehyde and DINP Aggravated Asthma-like Pathology through Oxidative Stress and NF-κB activation. Toxicology, 404–405: 49–58
3. Deng T, Zhang Y, Wu Y, Ma P, Duan JF, Qin W, Yang X, Chen MQ*. 2018. Dibutyl phthalate exposure aggravates type 2 diabetes by disrupting the insulin-mediated PI3K/AKT signaling pathway, Toxicology Letters, 290, 1-9.
4. Qin W, Deng T, Cui HY, Zhang Q, Liu XD, Yang Xu, Chen MQ*. 2018. Exposure to diisodecyl phthalate exacerbated Th2 and Th17-mediated asthma through aggravating oxidative stress and the activation of p38 MAPK. Food and Chemical Toxicology, 114:78-87.
5. Duan JF, Kang J, Qin W, Deng T, Liu H, Li BZ, Yu W, Gong SY, Yang X, Chen MQ*. 2018. Exposure to formaldehyde and diisononyl phthalate exacerbate Neuroinflammation through NF-κB activation in a mouse asthma model. Ecotoxicology and Environmental Safety, 163:356-364.
6. Kang J, Ding Y, Li BZ, Liu H, Yang X and Chen MQ *. 2017, TRPA1 mediated aggravation of allergic contact dermatitis induced by DINP and regulated by NF-κB activation. Sci.Rep.7, 43586; doi: 10.1038/srep43586.
7. Shen SP, Li JQ, You HH, Wu Z, Wu Y, Zhao Y, Zhu YQ, Guo Q, Li XX, Li R, Ma P, Yang X, Chen MQ *. 2017. Oral exposure to diisodecyl phthalate aggravates allergic dermatitis by oxidative stress and enhancement of thymic stromal lymphopoietin, Food and Chemical Toxicology, 99: 60-69
8. Kang J, Song J, Shen SP, Li BZ, Yang X and Chen MQ*. 2016. Diisononyl phthalate aggravates allergic dermatitis by activation of NF-κB, Oncotarget, 7(51): 85472-85482.
9. Yan B, Li JQ, Guo JH, Ma P, Wu Z, Ling ZH, Guo H, Hiroshi Y, Yanagi U, Yang X, Zhu SW *, Chen MQ *.2016.The toxic effects of indoor atmospheric fine particulate matter collected from allergic and non-allergic families in Wuhan on mouse peritoneal macrophages. Journal of Applied Toxicology, 36(4):596-608
10. Chen MQ, Sun F., Han L., Qu, ZX. 2016. Kaposi's sarcoma herpesvirus (KSHV) microRNA K12-1 functions as an oncogene by activating NF-κB/IL-6/STAT3 signaling. Oncotarget, 7(22), 33363-33373.
11. Zhu SW, Cai W, Yoshino H, Yanagi U, Hasegawa K, Kagi N, Chen MQ. 2015. Primary pollutants in schoolchildren's homes in Wuhan, China. Building and Environment, 93:41-53.
12. Min A, Liu FM, Yang X, Chen MQ*. 2014. Benzyl butyl phthalate exposure impairs learning and memory and attenuates neurotransmission and CREB phosphorylation in mice. Food and Chemical Toxicology,71: 81-89.
13. Zeng Q, Wei CX , Wu Y, Li K , Ding SM , Yuan JL , Yang X, Chen MQ *. 2013. Approach to distribution and accumulation of dibutyl phthalate in rats by immunoassay. Food and Chemical Toxicology, 56: 18-27
14. Chen MQ, Wei HB, Cao JW, Liu RJ, Wang YL, Zhen CY. 2007. Expression of Bacillus subtilis proBA genes and reduction of feedback inhibition of proline synthesis increases proline production and confers osmotolerance in transgenic Arabidopsis. Journal of Biochemistry and Molecular Biology, 40: 396-403.
15. Chen MQ, Cao JW, Zheng CY, Liu Q.2006. Directed evolution of an artificial bifunctional enzyme, γ-glutamyl kinase/γ-glutamyl phosphate reductase, for improved osmotic tolerance of Escherichia coli transformants. FEMS Microbiology Letters, 263: 41-47.
学术兼职（请以条目形式概括）
1. 担任Toxicological Sciences, Journal of Biological Chemistry, Food and Chemical Toxicology, Scientific Reports, Toxicology Research等刊物评审专家。
2. 中国环境科学学会室内环境与健康分会委员
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英文版：
Mingqing Chen


Title：Associate professor



Office Address：Room 315

Lab Address：Section of Environmental Biomedicine, Hubei Key Laboratory of Genetic Regulation and Integrative Biology

E-mail：chenmq@mail.ccnu.edu.cn

Resume:
Jul. 2007 to present: Assistant Professor, School of Life Sciences, Central China Normal University.
Mar.2014- Mar. 2015: Visiting scholar, University of Pittsburgh, School of Medicine.
Sep. 2002 - Jun.2007: Ph.D. in Biology, Wuhan University.
Sep. 1987 - Jun.1991: B. Sc. in Biology, Hubei University.
Research Interestes:
The influence of environmental pollutants on human health

Research Grants：
1. China National KeyR&D Program (2017YFC**), 2017.6.-2020.6
2. Self-determined research funds of CCNU from the colleges’ basic research and operation of MOE (CCNU17ZDJC05).2017.1-2017.12
3. China National KeyR&D Program (2016YFC07007), 2016.6-2018.12
4. National Natural Science Foundation of China (**), 2016.1-2018.12
5. National Key Technologies R&D Program of China (2012BAJ02B03), 2012.1-2016.12
6. National Key Technologies R&D Program of China (2012BAJ02B06), 2015.9-2016.10
7. National Key Technologies R&D Program of China (2012 BAJ02B05-1), 2015.1-2015.12
8. National Natural Science Foundation of China (**), 2011.1-2013.12
9. Natural Science Foundation of Hubei Province（2008CBD107）, 2009.1-2010.12
Representative Peer-reviewed Publications:
1. Duan JF, Kang J, Deng T, Yang X, Chen MQ*. 2018. Exposure to DBP and High Iodine Aggravates Autoimmune Thyroid Disease Through Increasing the Levels of IL-17 and Thyroid-Binding Globulin in Wistar Rats. Toxicological Sciences, 163(1):196–205.
2. Kang J, Duan JF, Song J, Luo C, Liu H, Li BZ, Yang X, Yu W*, Chen MQ*. 2018. Exposure to a Combination of Formaldehyde and DINP Aggravated Asthma-like Pathology through Oxidative Stress and NF-κB activation. Toxicology, 404–405: 49–58
3. Deng T, Zhang Y, Wu Y, Ma P, Duan JF, Qin W, Yang X, Chen MQ*. 2018. Dibutyl phthalate exposure aggravates type 2 diabetes by disrupting the insulin-mediated PI3K/AKT signaling pathway, Toxicology Letters, 290, 1-9.
4. Qin W, Deng T, Cui HY, Zhang Q, Liu XD, Yang Xu, Chen MQ*. 2018. Exposure to diisodecyl phthalate exacerbated Th2 and Th17-mediated asthma through aggravating oxidative stress and the activation of p38 MAPK. Food and Chemical Toxicology, 114:78-87.
5. Duan JF, Kang J, Qin W, Deng T, Liu H, Li BZ, Yu W, Gong SY, Yang X, Chen MQ*. 2018. Exposure to formaldehyde and diisononyl phthalate exacerbate Neuroinflammation through NF-κB activation in a mouse asthma model. Ecotoxicology and Environmental Safety, 163:356-364.
6. Kang J, Ding Y, Li BZ, Liu H, Yang X and Chen MQ *. 2017, TRPA1 mediated aggravation of allergic contact dermatitis induced by DINP and regulated by NF-κB activation. Sci.Rep.7, 43586; doi: 10.1038/srep43586.
7. Shen SP, Li JQ, You HH, Wu Z, Wu Y, Zhao Y, Zhu YQ, Guo Q, Li XX, Li R, Ma P, Yang X, Chen MQ *. 2017. Oral exposure to diisodecyl phthalate aggravates allergic dermatitis by oxidative stress and enhancement of thymic stromal lymphopoietin, Food and Chemical Toxicology, 99: 60-69
8. Kang J, Song J, Shen SP, Li BZ, Yang X and Chen MQ*. 2016. Diisononyl phthalate aggravates allergic dermatitis by activation of NF-κB, Oncotarget, 7(51): 85472-85482.
9. Yan B, Li JQ, Guo JH, Ma P, Wu Z, Ling ZH, Guo H, Hiroshi Y, Yanagi U, Yang X, Zhu SW *, Chen MQ *.2016.The toxic effects of indoor atmospheric fine particulate matter collected from allergic and non-allergic families in Wuhan on mouse peritoneal macrophages. Journal of Applied Toxicology, 36(4):596-608
10. Chen MQ, Sun F., Han L., Qu, ZX. 2016. Kaposi's sarcoma herpesvirus (KSHV) microRNA K12-1 functions as an oncogene by activating NF-κB/IL-6/STAT3 signaling. Oncotarget, 7(22), 33363-33373.
11. Zhu SW, Cai W, Yoshino H, Yanagi U, Hasegawa K, Kagi N, Chen MQ. 2015. Primary pollutants in schoolchildren's homes in Wuhan, China. Building and Environment, 93:41-53.
12. Min A, Liu FM, Yang X, Chen MQ*. 2014. Benzyl butyl phthalate exposure impairs learning and memory and attenuates neurotransmission and CREB phosphorylation in mice. Food and Chemical Toxicology,71: 81-89.
13. Zeng Q, Wei CX , Wu Y, Li K , Ding SM , Yuan JL , Yang X, Chen MQ *. 2013. Approach to distribution and accumulation of dibutyl phthalate in rats by immunoassay. Food and Chemical Toxicology, 56: 18-27
14. Chen MQ, Wei HB, Cao JW, Liu RJ, Wang YL, Zhen CY. 2007. Expression of Bacillus subtilis proBA genes and reduction of feedback inhibition of proline synthesis increases proline production and confers osmotolerance in transgenic Arabidopsis. Journal of Biochemistry and Molecular Biology, 40: 396-403.
15. Chen MQ, Cao JW, Zheng CY, Liu Q.2006. Directed evolution of an artificial bifunctional enzyme, γ-glutamyl kinase/γ-glutamyl phosphate reductase, for improved osmotic tolerance of Escherichia coli transformants. FEMS Microbiology Letters, 263: 41-47.