伍国锋
复旦大学医学博士，贵州医科大学博士生导师/二级教授、学科带头人，急诊医学教研室主任/附属医院急诊医学科主任，国家自然科学基金函审专家，省管专家，省政府特殊津贴专家，省级科技创新人才团队学术领衔人；中国医师协会急诊分会神经急诊专委会主任委员，中国卒中学会急救医学分会常委、中国医师协会神经调控专业委员会常委、中国老年医学会急诊医学分会常委、国家卫健委脑卒中防治工程委员会脑血管病急诊专业委员会常委，中华医学会急诊医学分会心脑血管病学组副组长，中国医师协会急诊医师分会委员，中国医师协会神经内科医师分会委员，贵州省急诊专科联盟主席；主持国家自然科学基金4项、省部级科研项目5项；获省部级科技进步奖一等2项（排名：1/9、4/15），获省部级科技进步奖二等奖2项（排名：1/7、5/8），获省部级科技进步奖三等奖2项（排名1/5）；在国内外专业杂志发表论文100余篇（SCI收录40余篇，北图核心期刊30余篇）；国内外学术大会演讲30余次；担任《Neuropsychiatry》、《Brain Hemorrhages》等杂志副主编，主编《神经内科急症》1部，副主编《高血压脑出血微创治疗学》1部，参编《急诊医学》、《病理生理学》、《脑血管病治疗学》、《急诊医学研究进展》及《癫痫病治疗学》各1部。
代表论文：
01.Wang, L. Shi, H. Kang, Y. Guofeng, W. Hippocampal low-frequency stimulation improves the cognitive function of pharmacoresistant epileptic rats. Epilepsy Research. 2019 Sep 11:106194. doi: 10.1016/j.eplepsyres.2019.106194.
02. Qi Li , Yi Qing Shen, XiongFei Xie, MengZhou Xue, Du Cao, WenSong Yang, Rui Li, Lan Deng, Miao Wei, FaJin Lv, GuoFeng Wu, ZhouPing Tang and Peng Xie. Expansion-Prone Hematoma: Defining a Population at High Risk of Hematoma Growth and Poor Outcome. Neurocritical Care. 2019，30(3):601-608
03. Kaya Xu, Feng Liu, Wei Xu, Jian Liu, Shuxuan Chen, Guofeng Wu.Transplanting GABAergic Neurons Differentiated from Neural Stem Cells into Hippocampus Inhibits Seizures and Epileptiform Discharges in Pilocarpine-Induced Temporal Lobe Epilepsy Model. World Neurosurgery,2019,128:E1-E11
04.Guofeng Wu, Jinpeng Yu, Likun Wang, Siying Ren, Yixia Zhang. PKC/CREB pathway mediates the expressions of GABA_A receptor subunits in cultured hippocampal neurons after low-Mg2+ solution treatment. Epilepsy Research, 2018, 140:155-161
05. Guofeng Wu, Yu Jiao, Junjie Wu, Riying Ren, Likun Wang, Zhouping Tang, Houguang Zhou. Rosiglitazone Infusion Therapy Following Minimally Invasive Surgery for Intracranial Hemorrhage Evacuation Decreased Perihematomal Glutamate Content and Blood-Brain Barrier Permeability in Rabbits. World Neurosurgery.2018,111:e40-e46
06.Zhengkui Shen1, Likun Wang, Guofeng Wu, Qi Li,Riying Ren , Yuanhong Mao. CT black hole sign predicts post-operative rehaemaorrhage in patients with spontaneous ICH following stereotactic minimally invasive surgery. World Neurosurgery.2018, online
07. Kaya Xu, Zhaoyang Liu, Likun Wang, Guofeng Wu,Tao Liu. Influence of hippocampal low-frequency stimulation on GABAA R α1, ICER and BNDF expression level in brain tissues of amygdala-kindled drugresistant temporal lobe epileptic rats. Brain Research,2018,1698：195-203
08. Guofeng Wu, Fan Wang, Likun Wang, Jing Shi, MD,Hui Yu and Yingjun Zhang. Minimally Invasive Surgery for Evacuating the Intracerebral Hematoma in Early Stages Decreased Secondary Damages to the Internal Capsule in Dog Model of ICH: Observed by Diffusion Tensor Imaging. Journal of Stroke and Cerebrovascular Diseases. 2017, 26(4):701-7（2016-2017, IF=1.73）
09.Guofeng Wu, Likun Wang, Zhen Hong, Siying Ren and Feng Zhou.Hippocampal low-frequency stimulation inhibits afterdischarge and increases GABA (A) receptor expression in amygdala-kindled pharmacoresistant epileptic rats. Neurological Research. 2017，May , 39(8):733-743（2016-2017，IF=1.54）
10.Qiong Mu, Likun Wang, Hang Hang, Chunfeng Liu, Guofeng Wu. Rosiglitazone pretreatment influences thrombin-induced phagocytosis by rat microglia via activating PPAR and CD36. Neuroscience Letters. 2017, 651 :159–164（2016-2017，IF=2.23）
11.Guofeng Wu, Zhengkui Shen, Likun Wang, Shujie Sun, Jinbiao Luo and Yuanhong Mao. Post-operative re-bleeding in patients with hypertensive ICH is closely associated with the CT blend sign. BMC Neurology.2017,17:131-138（2016-2017，IF=2.41）
12.Jing Shi, Guofeng Wu, Xiaohua Zou, Ke Jiang. Oleuropein protects intracerebral hemorrhage-induced disruption of blood-brain barrier through alleviation of oxidative stress. Pharmacological Reports. 2017,69：1206-1212（2016-2017, IF=2.587）
13.Guofeng Wu, Junjie Wu, Likun Wang , Yu Jiao , Houguang Zhou , Zhouping Tang.Minimally invasive surgery for ICH evacuation followed by rosiglitazone infusion therapy increased perihematomal PPARγ expression and improved neurological outcomes in rabbits. Neurol Res.2016 Apr 15:1-8. 14.Guofeng Wu, Junjie Wu, Yu Jiao, Likun Wang, Fan Wang, Yingjun Zhang.Rosiglitazone infusion therapy following minimally invasive surgery for intracerebral hemorrhage evacuation decreases matrix metalloproteinase-9 and blood-brain barrier disruption in rabbits. BMC Neurology.2015, 15（37）：1471-2337
15.Likun Wang, Fan Wang, Guofeng Wu, Jing Shi.Early-stage minimally invasive procedures decrease perihematomal endothelin-1 levels and improve neurological functioning in a rabbit model of intracerebral hemorrhage. Neurol Res，2015，37（4）：320-327
16.Jin Shi. Likun Wang, Guofeng Wu. Synaptic vesicle protein2A decreases in amygdaloid-kindling pharmcoresistant epileptic rats. Journal of Huazhong University Science and Technology(Med Sci). 2015，35（5）716-722,
17.Guofeng Wu, Jing Shi, Fan Wang, Likun Wang. Effects of minimally invasive procedures for evacuation of intracerebral hematoma in early stages on MMP-9 and BBB permeability in rabbits. BMC Neurology.2014, 14(85):1-9
18.Likun Wang, Jing Shi, Guofeng Wu(通讯作者),Feng Zhou, Zhen Hong. Hippocampal low-frequency stimulation increased SV2A expression and inhibited the seizure degree in pharmacoresistant amygdala-kindling epileptic rats. Epilepsy Research.2014,108（9）: 1483—1491
19.Guofeng Wu, , Likun Wang, Jian Liu, Yuanhong Mao, and Guannan Qin. Minimally Invasive Procedures Reduced the Damages to Motor Function in Patients with Thalamic Hematoma: Observed by Motor Evoked Potential and Diffusion Tensor Imaging.Journal of Stroke and Cerebrovascular Diseases.2013: pp 232-240
20.Likun Wang, Guofeng Wu, Yuanhong Mao,et al.Minimally invasive procedures reduce perihematomal endothelin-1 levels and the permeability of the BBBin a rabbit model of intracerebral hematoma. Neurological Sciences.2013, 34(1):41-9.
21.Guofeng Wu, Likun Wang. Minimally invasive procedures for intracerebral hematoma evacuation in early stages decrease perihematomal glutamate level and improve neurological function in a rabbit model of ICH. Brain Res. 2013, 1492: 140-7
22.Wu Guofeng, Hongzhen, Liyan，Zhou Feng. Hippocampal stimulation increased GABA(B) receptor expression in the brain tissues of amygdaloid kindling pharmacoresistant epileptic rats .Neuromodulation. 2013; 16: 105–113
23.Guofeng Wu, Shujie Sun, Xianyue Long, Likun Wang, Siying Ren.Early stage minimally invasive procedures reduce perihematomal MMP-9 and blood–brain barrier disruption in a rabbit model of intracerebral hemorrhage.Neurological Research，2013.35（6）：649-658
24. Likun Wang, Guofeng Wu, Chang Li, et al. Perihematomal endothelin-1 level is associated with an increase in blood-brain barrier permeability in a rabbit model of intracerebral . Chinese Medical Journal. 2013, 126(18):3433-8
25.Wu Guofeng, Sheng Fei, Wang Likun, Wang Fan. The pathophysiological time window study of performing minimally invasive procedures for the intracerebral hematoma evacuation in rabbit. Brain Res 2012;1465:57-65.
26.Guofeng Wu, Shen Li, Likun Wang, Yuanhong Mao.The perihematomal glutamate level is associated with the outcome of patients with basal ganglia hematomas treated by minimally invasive procedures.Neurological Research.2013，35 ：829-835
27. Guofeng Wu, Likun Wang, Yuanhong Mao, Zhen Hong. Minimally Invasive Procedures for Evacuation of Intracerebral Hemorrhage Reduces Perihematomal Glutamate Content, Blood–Brain Barrier Permeability and Brain Edema in Rabbits. Neurocrit Care.2011,14:118–126
28.Wu Guofeng, Wang Likun, Hong Zheb, Li Chang, Long Xianyue, Sheng Fei.. Effects of minimally invasive procedures for removal of intracranial hematoma on matrix metalloproteinase expression and blood-brain barrier permeability in perihematomal brain tissues. Neurol Res 2011;33:300-306.
29.Wu Guofeng, Wang Likun, Hong Zhen, Mao Yuhong, Hu Xiaochun. Effects of minimally invasive techniques for evacuation of hematoma in basal ganglia on cortical spinal tract from patients with spontaneous hemorrhage: observed by diffusion tensor imaging.Neurol Res.2010;32:1103-1109.
30.Wu Guofeng, Zhong Weibin. Effect of minimally invasive surgery for cerebral hematoma evacuation in different stages on motor evoked potential and thrombin in dog model of intracranial hemorrhage. Neurol Res. 2010;32:127-133.