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刘庆友
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亚热带农业生物资源保护与利用国家重点实验室，南宁市大学东路100号
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动物科学技术学院
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刘庆友，研究员，博士生导师，广西卓越****，亚热带农业生物资源保护与利用国家重点实验室固定人员。2007年博士毕业于中科院北京基因组研究所。2007年广西大学硕士导师，2011年获评研究员职称，2013年广西大学博士生导师。主要从事动物基因组学、功能基因组学、基因编辑、纳米口服疫苗等生物技术研究，研究获得染色体级别的沼泽型水牛和河流型水牛全基因组序列图，挖掘了了沼泽型水牛温顺性格形成相关和役力适应性进化选择相关基因。主持国家自然基金课题4项，主持863子课题1项，广西重点研发课题2项。发表论文150余篇，其中2020年以通讯作者发表SCI论文11篇。包括知名期刊《National science review》IF16.69《 Journal of nanobiotechnology》《J. Cell. Physiol.》《Frontiers in Genetics》《theriogenology》《Journal of dairy science》等。
xsjz
全国畜牧学科高峰论坛副秘书长；中国畜牧兽医学会高级会员；国家农业基因组科技创新联盟理事；广西实验动物学会理事。《Journal of dairy science》《Scientific Reports》《theriogenology》等杂志审稿专家；《Frontiers in Genetics 》reviewer editor,《黑龙江动物繁殖》常务编委。国家自然基金、广西科学基金等评审专家。
zyyjskc
基因组学与生物信息学、动物保护学、畜牧前沿进展等课程。
zyyjfx
动物基因组学、功能基因组学、基因编辑、纳米口服疫苗
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1. 水牛重要经济性状基因组学与功能基因组学研究，国家自然基金联合基金重点项目，260万，202101-202412，主持；2.应用基因捕获高通量测序精准鉴定影响水牛产奶性状的关键基因研究，国家自然基金，39万，201901-202212，主持；3.广西高等学校卓越****高水平创新团队，120万，2018/08-2021/08，主持；4.通过干预肠道微生物实现水牛生态养殖的关键技术研究，广西重点研发，60万，201810-202010主持；5.高产意大利奶用水牛新品种引进与繁育技术研究，广西重点研发，100万，2016/09-2019/12，主持；6.基于全外显子测序的水牛不同时期卵巢转录组研究，国家自然基金，52万，2013.01-2016.12，主持；7.组蛋白药物人白细胞介素-2奶山羊乳腺生物反应器研制，计划内横向，10万，2014.11-2017.11，主持；8.奶牛重要经济性状的功能基因组学研究----水牛繁殖性状的功能基因组学研究，863计划，155万，2013.01-2017.12； 9.新型动植物生物反应器创制，863计划，1145万，2011.04-2015.12，参加；10.水牛胎儿成纤维细胞诱导为多能干细胞的初步研究，国家自然基金，2010.01-2012.12，**，23.0万，已结题，主持；11.高繁殖力和高产奶量的转基因水牛新品种培育，国家农业部，2008.07-2010.12，2008ZX08007-003，总经费2681.0，已结题，子任务负责人；12.抗乳房炎转基因奶水牛和奶牛的研究，广西科技厅，2009.03-2012.03，桂科自**Z，13.0万，已结题，主持；13.应用转基因娟姗牛乳腺生产人药用干扰素的研究，南宁市科技局，2010.03-2013.03，G，20.0万，主持。
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1.Xier Luo, Yu Zhou, Bing Zhang, Yi Zhang, Xiaobo Wang, Tong Feng, Zhipeng Li, Kuiqing Cui, Zhiqiang Wang, Chan Luo, Hui Li, Yanfei Deng, Fenghua Lu, Jianlin Han, Yongwang Miao, Huaming Mao, Xiaoyan Yi, Cheng Ai, Shigang Wu, Alun Li, Zhichao Wu, Zijun Zhuo, Do Da Giang, Bikash Mitra, Mohammad Farhad Vahidi, Shahid Mansoor, Sahar Ahmed Al-Bayatti, Eka Meutia Sari, Neena Amatya Gorkhali, Sigit Prastowo, Laiba Shafique, Guoyou Ye, Qian Qian, Baoshan Chen, Deshun Shi*, Jue Ruan*, Qingyou Liu*，Understanding divergent domestication traits from the whole-genome sequencing of swamp and river buffalo populations，National Science Review，2020，7：686-701. doi: 10.1093/nsr/nwaa024. 2.Zhang Haihang, Li Yushan, Cui Kuiqing, Chen Xiu, Shang Cuiling, Min Wanping, Jin Peng, Jiang Zhaodi, Shi Deshun, Liu Qingyou*, Wang Fengchao. Male fertility in Mus musculus requires the activity of TRYX5 in sperm migration into the oviduct.[J]. J. Cell. Physiol., 2020 ;235(9):6058-6072. doi:10.1002/jcp.29534. 3.Hui Li, Kongwei Huang, Kuiqing Cui, Pengcheng Wang, Tong Feng, Deshun Shi, Chan Luo, Laiba Shafique, Qian Qian, Jue Ruan, Qingyou Liu*, Comparison of Long Non-coding RNA Expression Profiles of Cattle and Buffalo Differing in Muscle Characteristics，Frontiers in Genetics，2020;11:98. Published 2020 Feb 26. doi:10.3389/fgene.2020.00098. 4.Yang C, Zheng H, Moussa M, Amin A, Huang J, El-Sayed A, Shang J, Liu Q*. Effects of laser zona thinning and artificial blastocoel collapse on the cryosurviving and hatching of buffalo (Bubalus bulalis) blastocysts of different ages. Theriogenology. 2020;147:197-201. doi:10.1016/j.theriogenology.2019.11.015.5.Sun J, Cui K, Li ZP, Gao B, Huang B, Liu Q*, Shi D*. Improved early development potence of in vitro fertilization embryos by treatment with tubacin increasing acetylated tubulin of matured porcine oocytes [published online ahead of print, 2020 Aug 20]. Mech Dev. 2020;103631. doi:10.1016/j.mod.2020.103631.6.Rehman SU, Shafique L, Ihsan A*, Liu Q*. Evolutionary Trajectory for the Emergence of Novel Coronavirus SARS-CoV-2. Pathogens. 2020;9(3):240. Published 2020 Mar 23. doi:10.3390/pathogens**.7.Li Z, Lu S, Cui K, Shafique L, Rehman SU, Luo C, Wang Z, Ruan J, Qian Q, Liu Q*. Fatty acid biosynthesis and transcriptional regulation of Stearoyl-CoA Desaturase 1 (SCD1) in buffalo milk. BMC Genet. 2020;21(1):23. Published 2020 Mar 2. doi:10.1186/s12863-020-0829-6. 8.Tong Feng, Zilu Zhang, Minghao Qu, Chan Luo, Laiba Shafique, Qingyou Liu*, and KuiQing Cui* Three SNPs Identified in the MC1R Gene of Nubian Goats may Relate to the Wool Color，Pakistan J. Zool., 2020，52(3)：843-847. 9.Lingyan Lv, Xingrong L, Tong Feng, Saif ur Rehman, Junming Sun, Zhuyue Wu, Deshun Shi, Qingyou Liu*, Kuiqing Cui, Valproic acid enhances in vitro developmental competence of porcine handmade cloned embryos, Livestock Science，2020, 233, 103957. 10.Jinfeng Liu, Yanhong Cao, Tong Feng, Laiba Shafique, Chan Luo, Peng Zhu* and Qingyou Liu*,Expression Patterns of BMP15 Gene in Folliculogenesis of Buffalo (Bubalus bubalis)Pakistan J. Zool.,2020, 52(1)：37-47. 11.Rehman SU, Nadeem A, Javed M, Hassan FU, Luo X, Khalid RB, Liu Q. Genomic Identification, Evolution and Sequence Analysis of the Heat-Shock Protein Gene Family in Buffalo. Genes (Basel). 2020 Nov 23;11(11):1388. doi: 10.3390/genes**. 12.Li Zhipeng, Cui Kuiqing, Wang Hong, Liu Fuhang, Huang Kongwei, Duan Zhaojun, Wang Fengchao, Shi Deshun*, Liu Qingyou*. A milk-based self-assemble rotavirus VP6-ferritin nanoparticle vaccine elicited protection against the viral infection.[J]. Journal of nanobiotechnology, 2019, 17(1):13.13.Xiao Ning, Li Hongli, Shafique Laiba, Zhao Shanshan, Su Xiaoping, Zhang Yu, Cui Kuiqing, Liu Qingyou*, Shi Deshun*. A Novel Pale-Yellow Coat Color of Rabbits Generated via MC1R Mutation With CRISPR/Cas9 System.[J]. Frontiers in genetics, 2019, 10.14.Li Zhipeng, Cui Kuiqing, Huang Kongwei, Liu Fuhang, Shi Deshun*, Liu Qingyou*. Self-assembling Rotavirus VP6 Nanoparticle Vaccines Expressed in Escherichia coli Elicit Systemic and Mucosal Responses in Mice.[J]. Protein and peptide letters, 2019, 26(12):904-90915.Le J, Lei X, Ren Y, Li Z, Tu H, Ding F, Yi X, Zhou Y, Liu Q*, Zhang S*，Exogenous oestradiol benzoate induces male mice azoospermia through modulation of oxidative stress and testicular metabolic cooperation, Mol Med Rep. 2019, 19(6):4955-496316.Li Hongli, Li Zhipeng, Xiao Ning, Su Xiaoping, Zhao Shanshan, Zhang Yu, Cui Kuiqing, Liu Qingyou*, Shi Deshun*. Site-specific integration of rotavirus VP6 gene in rabbit β-casein locus by CRISPR/Cas9 system.[J]. In vitro cellular & developmental biology. Animal, 2019, 55(8):586-59717.Cai Xiaoyan#, Liu Qingyou#, Zhang Xiaoxi, Ren Yanping, Lei Xiaocan, Li Sheng, Chen Qiuping, Deng Kai,Wang Ping, Zhang Haihang, Shi Deshun. Identification and analysis of the expression of microRNA from lactating and nonlactating mammary glands of the Chinese swamp buffalo.[J]. Journal of dairy science, 2017, 100(3):1971-198618.Lei X, Cui K, Cai X, Ren Y, Liu Q*, Shi D.Bone morphogenetic protein 1 is expressed in porcine ovarian follicles and promotes oocyte maturation and early embryonic development. J Vet Med Sci. 2017, 79(2):258-26619.Lei Xiaocan, Cui Kuiqing, Li Zhipeng, Su Jie, Jiang Jianrong, Zhang Haihang, Liu Qingyou*, Shi Deshun*. BMP-1 participates in the selection and dominance of buffalo follicles by regulating the proliferation and apoptosis of granulosa cells.[J]. Theriogenology, 2016, 85(5):999-1012.20.Lei X#, Cui K#, Liu Q#, Zhang H, Li Z, Huang B, Shi D. Exogenous Estradiol Benzoate Induces Spermatogenesis Disorder through Influencing Apoptosis and Oestrogen Receptor Signalling Pathway.[J]. Reproduction in domestic animals, 2016, 51(1):75-84.
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