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广西大学动物科学技术学院教授、博士生导师、副院长。入选广西优秀专家、广西高校引进海外高层次人才“****”，获广西青年五四奖章、广西****基金、霍英东教育基金。留学德国杜塞尔多夫大学、法国原子能委员会（巴黎）、美国宾夕法尼亚大学（费城）。主持国家自然科学基金、广西自然科学基金重点项目、霍英东教育基金、欧洲糖尿病研究基金、中欧、中日合作项目、教育部留学回国人员科研启动基金、教育部新教师基金等。在《Hepatology》、《Nucleic Acids Research》等国内外学术刊物上发表论文40余篇。
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中国畜牧兽医学会动物生理生化学分会理事 中国畜牧兽医学会动物遗传育种学分会理事中国生物化学与分子生物学会农业生物化学与分子生物学分会理事广西实验动物学会常务理事广西畜牧兽医学会理事 亚热带农业生物资源保护与利用国家重点实验室固定研究人员Frontiers in Endocrinology--Associate Editor
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动物生理学动物生物化学
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①营养、基因与代谢稳态；②动物肉质形成的分子基础及其调控；③细胞分化中的编程与重编程；④动物功能基因的转录调控和信号转导；⑤动物脂肪发育的分子机制及其调控；⑥营养组学研究（功能基因组、表观基因组、蛋白质组、蛋白质修饰组）。
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1. 广西大学高层次专业技术人才培养工程“杰出人才培养计划”。2. 国家自然科学基金。3. 广西高校引进海外高层次人才“****”。4. 广西自然科学基金重点项目。5. 广西大学科研基金（引进人才项目）。6. 欧洲糖尿病研究基金项目（EFSD，欧洲基金会资助）。7. 教育部博士点新教师基金。8. TANITA健康体重基金（日本基金会资助）。
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取得了以下研究进展：一、在动物整体水平上，发现抵抗素减少线粒体、增强脂肪异位沉积二、在细胞水平上，证实脂肪细胞因子参与葡萄糖代谢、肌肉发育及炎症反应三、在遗传水平上，开展猪脂肪代谢相关基因的克隆及转录调控研究课题组常年招聘博士后、博士生、硕士生，待遇从优，提供良好的职业发展机会。课题组情况分子营养课题组依托广西大学动物科学技术学院和亚热带农业生物资源保护与利用国家重点实验室，从组学水平研究糖脂代谢调控，在医学上主要针对肥胖、糖尿病、脂肪肝等代谢疾病；在畜牧上研究脂肪性状对繁殖、肉质、瘦肉率的调控。已在Hepatology、Nucleic Acids Research等高水平杂志上发表多篇论文。课题组长周老师入选广西自治区****、广西大学杰出人才培养计划，团队承担多项国家级、省部级研究课题。1. 周老师从科研思路、实验技能和论文写作方面亲自指导学生，与学生一起做研究，全方位培养学生2. 课题组与美国、德国等多个课题组保持着长期合作关系，优秀研究生和博士后根据项目进展和合作需要，有机会赴德国或美国进行联合培养或合作研究，毕业或出站后尽力推荐去国外一流课题组继续深造3. 博士后和研究生每年至少参加一次国内学术会议4. 课题组工作氛围轻松友善，为团队成员提供实现自身价值的机会及发展空间5. 先进的课题组运行模式，每个成员都有独立项目6. 较为充足的研究经费（详见主持项目）7. 充足的实验空间和优良的实验设备，具有课题组专用的洁净室和动物房。发表论文：第一或通讯作者（*）1.Lei Zhou*, Xiaolan Yu, Qingjie Meng, Hongqiang Li, Congcong Niu, Yun Jiang, Yuxi Cai, Minghui Li, Qiang Li, Chaoqiang An, Le Shu, Ao Chen, Handong Su, Yin Tang, Shen Yin, Silja Raschke, Kristin Eckardt, Juergen Eckel, Zaiqing Yang*. Resistin reduces mitochondria and induces hepatic steatosis in mice by the protein kinase C/protein kinase G/p65/PPAR gamma coactivator 1 alpha pathway. Hepatology. 2013, 57: 1384-1393. IF：14.9712.Lei Zhou, Gwenaelle Le Roux, Cecile Ducrot, Stephane Chedin, Jean Labarre, Michel Riva, Christophe Carles*. Repression of class I transcription by cadmium is mediated by the Protein Phosphatase 2A. Nucleic Acids Res. 2013, 41: 6087–6097. IF：11.1473.Yixing Li, Kejing Wu, Weili Quan, Lin Yu, Shuang Chen, Chao Cheng, Qijia Wu, Shuhong Zhao, Yi Zhang*, Lei Zhou*. The dynamics of FTO binding and demethylation from the m6A motifs. RNA Biology. 2019, 16: 1179–1189. IF：5.4774.Zupeng Luo, Zhiwang Zhang, Lina Tai, Lifang Zhang, Zheng Sun, Lei Zhou*. Comprehensive analysis of differences of N6-methyladenosine RNA methylomes between high-fat-fed and normal mouse livers. Epigenomics. 2019, 11(11): 1267-1282. IF: 4.404 5.Zhanyang Tang, Yi Zhou, Jun Xiao, Huan Zhong, Weiwei Miao, Zhongbao Guo, XuZhang, Lei Zhou*, Yongju Luo*. Transcriptome Analysis of Ovary Development in Nile Tilapia Under Different Photoperiod Regimes. Frontiers in Genetics. 2019, 10: 894. IF: 3.5176.Lifang Zhang, Yilin Qi, Zhier ALuo, Siqi Liu, Zhiwang Zhang and Lei Zhou*. Betaine increases mitochondrial content and improves hepatic lipid metabolism. Food Funct., 2019, 10: 216-223. IF：3.2417.Qiang Li, Yixing Li, Zhiwang Zhang, Huifang Kang, Lifang Zhang, Yuxiang Zhang, Lei Zhou*. SEIPIN overexpression in the liver may alleviate hepatic steatosis by influencing the intracellular calcium level. Mol Cell Endocrinol. 2019, 488: 70-78. IF：3.6938.Li Y, Luo Z, Wu X, Zhu J, Yu K, Jin Y, Zhang Z, Zhao S, Zhou L*. Proteomic Analyses of Cysteine Redox in High-Fat-Fed and Fasted Mouse Livers: Implications for Liver Metabolic Homeostasis. J Proteome Res. 2018, 17(1): 129-140. IF：3.789.Kang Huifang, Zhang Zhiwang, Yu Lin, Li Yixing*, Liang Mingzhen, Zhou Lei*. FTO reduces mitochondria and promotes hepatic fat accumulationthrough RNA demethylation. Journal of Cellular Biochemistry. 2018, 119(7): 5676-5685. IF：3.44810.Yixing Li, Huifang Kang, Yi Chu, Yi Jin, Lifang Zhang, Ranran Yang, Zhiwang Zhang, Shuhong Zhao, Lei Zhou*. Cidec differentially regulates lipid deposition and secretion through two tissue-specific isoforms. Gene. 2018, 641C: 265-271. IF：2.41511.Lin Yu, Lina Tai, Lifang Zhang, Yi Chu, Yixing Li*, Lei Zhou*. Comparative analyses of long non-coding RNA in lean and obese pig. Oncotarget. 2017, 8(25): 41440-41450. IF：5.16812.Yuxiang Zhang, Yixing Li, Lin Yu, Lei Zhou*. Association between serum resistin concentration and hypertension: A systematic review and meta-analysis. Oncotarget. 2017, 8(25): 41529-41537. IF：5.16813.Yixing Li, Yi Chu, Lin Yu, Huifang Kang, Lei Zhou*. Transcriptomic analysis of Bama pig's liver in various nutritional status reveals a metabolic difference of fatty acid. Food & Function. 2017, 8: 3480-3490. Cover Paper, IF：3.24714.Qiang Li, Yuxi Cai, Jing Huang, Xiaolan Yu, Jun Sun, Zaiqing Yang*, Zhou L*. Resistin impairs glucose permeability in EA.hy926 cells by downregulating GLUT1 expression. Mol Cell Endocrinol. 2016, 434: 127-34. IF：3.75415.Jiang Y, Lu L, Hu Y, Li Q, An C, Yu X, Shu L, Chen A, Niu C, Zhou L*, Yang Z*. Resistin Induces Hypertension and Insulin Resistance in Mice via a TLR4-Dependent Pathway. Sci Rep. 2016, 6: 22193. IF：4.25916.Y Li, L Zhou*, Vitamin D Deficiency, Obesity and Diabetes. Cell Mol Biol. 2015, 61(3): 35-38. IF：0.9217.Li H, Chen A, Shu L, Yu X, Gan L, Zhou L*, Yang Z*. Translocation of CIDEC in hepatocytes depends on fatty acids. Genes Cells. 2014, 19(11): 793-802. IF：1.99318.Lei Zhou, Lijie Zhang, Qingjie Meng, Congcong Niu, Dan Jin, An Yu, Li gan, Zaiqing Yang. C/EBP promotes transcription of the porcine perilipin5 gene. Mol Cell Endocrinnol. 2012, 364:28-35. IF：3.75419.Lei Zhou, Qingjie Meng, Tao Qian, Zaiqing Yang. Ginkgo biloba extract enhances glucose tolerance in hyperinsulinism-induced hepatic cells. J Nat Med. 2011, 65(1): 50-6. IF：1.98220.Lei Zhou, Henrike Sell, Kristin Eckardt, Zaiqing Yang, Jürgen Eckel. Conditioned medium obtained from in vitro differentiated adipocytes and resistin induce insulin resistance in human hepatocytes. FEBS letters. 2007, 581: 4303-4308. IF：3.62321.Lei Zhou, Yixing Li, Tao Nie, Shengqiu Feng, Huaping Chen, Zaiqing Yang. Clenbuterol inhibits SREBP-1c expression by activating CREB1. J BIOCHEM MOL BIOL. 2007, 40(4): 525-31. IF：2.02122.Lei Zhou, Yixing Li, Tao Xia, Shengqiu Feng, Xiaodong Chen, Zaiqing Yang. Resistin Overexpression Impaired Glucose Tolerance in Hepatocytes. Eur Cytokine Netw. 2006, 17(3): 189-95. IF：2.36423.Lei Zhou, Tao Xia, Yixing Li, Xiaodong Chen, Yin Peng, Zaiqing Yang. Transcriptional Regulation of the Resistin Gene. Domest Anim Endocrinol. 2006, 30(2): 98-107. IF：1.644
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1.广西高层次人才2.广西优秀专家3.广西****基金4.广西****5.广西青年五四奖章
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