董钰明
职务/职称：教授/硕导
研 究 所：药物分析研究所
联系电话：
电子邮件：dongym@lzu.edu.cn
办 公 室：勤博楼2019室

个人简介
研究成果
研究项目

【基本情况】
1994年毕业于兰州大学药学院药学专业并获医学学士学位。1996年3月-1997年3月在中国药科大学药学院药物分析教研室进修学习，指导老师为刘文英教授。2002年毕业于兰州大学药学院生药学专业（药物分析方向）并获医学硕士学位，指导教师为段生玉教授和封士兰教授；2006年毕业于兰州大学化学化工学院分析化学专业并获理学博士学位，指导教师为陈兴国教授。1994年～2004年在兰州医学院药学系药物分析教研室任助教、讲师，其中1997年-1998年在甘肃省武山县卫生局挂职锻炼；2004年～2009年在兰州大学药学院任讲师；2007年～2010年先后在台湾长庚大学和美国新奥尔良大学从事博士后研究；2009年～2014年在兰州大学药学院任副教授、硕士研究生导师，2014年～至今，在兰州大学药学院任教授、硕士研究生导师。2016年8月-2017年8月在江苏张家港保税区科技人才局任副局长（挂职）。
现任兰州大学药学院药物分析教研室主任，甘肃省药学会药物分析专业委员会主任委员，甘肃省中药品质安全评价工程中心学术委员会副主任委员、《药物分析杂志》和《兰州大学学报》（医学版）编委。省级一流本科课程《药物分析》课程负责人。
【研究方向】
胶束液相色谱新方法及其在药物分析中的应用研究；毛细管电泳新方法及其在药物分析中的应用研究；新型HPLC整体柱的制备及其在药物分析中的应用研究；分析仪器的开发；医疗机构制剂、新药的开发研究。
【主讲课程】
主讲本科生《药物分析学》理论课和实验课以及面向全校本科生的通识选修课《药物与生活》，研究生《现代药物分析》和《药物分析新技术和新方法》等课程。
【获奖情况】
先后获得2010、2013年兰州大学创新创业项目优秀指导教师、2011年“之德基金”项目优秀指导教师，2016年兰州大学创新创业项目优秀指导教师二等奖。2017年大学生课外学术作品“挑战杯”优秀指导教师称号。
1.Jing Zhang,Yufei Zhang,Haixia Ma,Fatang Yang,Tianjiao Duan,Yuhui Zhang,Yuming Dong*，Quantitative analysis of nine isoflavones in traditional Chinese medicines using mixed micellar liquid chromatography containing sodium dodecylsulfate/β-cyclodextrin supramolecular amphiphiles，Journal of Separation Science, 2021, https://doi.org/10.1002/jssc.
2.Ning Li, Shujuan He, Chunlan Li, Fatang Yang,Yuming Dong*, Sensitive Analysis of Metoprolol Tartrate and Diltiazem Hydrochloride in Human Serum by Capillary Zone Electrophoresis Combining on Column Field-Amplified Sample Injection, Journal of Chromatographic Science,2021, 59（5）：465-472.
3.Fatang Yang,Xiaoyun Duan,Zhen Wang,Yuming Dong*, A gas chromatography flame ionization detector method for rapid simultaneous separation and determination of six active ingredients of anticold drug, Current Pharmaceutical Analysis, 2021, Doi10.2174/**211.
4.Tianjiao Duan, Haixia Ma, Yuming Dong, Fatang Yang, Xiaofeng Liu*，Microemulsion liquid chromatographic method for simultaneous separation and determinationof five isoflavones in red clover.Journal of Liquid Chromatography & Related Technologies，2021，Doi:10.1080/**.2020.**.
5.董钰明*，杨法棠，刘晖，王兆彦，陈娟，网络环境下基于慕课的药物分析学PBL教学模式研究，药学教育，2020，36（2）：52-57.
6.Peng Li , Xiao-Hui Ma , Yu-Ming Dong , Ling Jin*, Juan Chen*, α-Glucosidase immobilization on polydopamine-coated cellulose filter paper and enzyme inhibitor screening, Analytical Biochemistry,2020,605,113832.
7.Xiaoyun Duan, Xiaofeng Liu, Yue Dong, Jing Yang, Jing Zhang, Shujuan He, Fatang Yang, Zhen Wang, and Yuming Dong*，A Green HPLC Method for Determination of Nine Sulfonamides in Milk and Beef, and Its Greenness Assessment with Analytical Eco-Scale and Greenness Profile，Journal of AOAC INTERNATIONAL，2020，103（4）：1181-1189.
8.Xiaoyun Duan,Xiaofeng Liu，Yue Dong，Tianjiao Duan，Jing Zhang， Shujuan He，Fatang Yang，Yuming Dong*，A Mixed Micellar Liquid Chromatography with Direct Injection for Rapid Analysis of Eight Sulfonamides in Milk，Food Analytical Methods，2020，13：1148-1158.
9.Shujuan He,Jing Zhang, Yue Dong,Xiaoyun Duan,Fatang Yang,Tian Luo, Zhen Wang,Yuming Dong*,Establishment and development of a CZE–UV method for rapid measurement of aprotinin potency,Electrophoresis,2020, 41（3-4）：168-174.
10.Tian Luo, Shujuan He, Yueting Deng,Ximin Zhang, Yuming Dong*. Establishing tablet dissolution curve through determination of underivatized alendronate sodium by capillary electrophoresis-UV detector, Current Pharmaceutical Analysis, 2020,16（5）：615-622.
11.董钰明*，刘晖，王兆彦，陈娟，药学专业研究生现代现代药物分析课程教学中面临的问题及解决对策，卫生职业教育，2019，37（8）：21-23.
12.Xiaoyun Duan, Xiaofeng Liu, Yue Dong, Jing Zhang, Shujuan He, D. Serge Uhagaze, Fatang Yang ,Yuming Dong*, A micellar HPLC method for simultaneous determination of six active ingredients in cold compound preparations, Journal of Liquid Chromatography & Related Technologies, 2019,42: 485-493.
13.Jing Ke, Xiaoyun Duan, Xiaofeng Liu, Yuming Dong*,Isocratic micellar liquid chromatography using mixed anionic and non-ionic surfactants as mobile phase additives for separation of 17 free amino acid，Chemical Papers,2019, 73：2417-2426.
14.Jing Yang, Shujuan He, Aihui Liu, Juan Chen,Yuming Dong*,Preparation of a poly(1, 6-hexylene dimethacrylate) conventional size high performance liquid chromatographic monolithic column for separation of small molecule, Microchemical Journal,2019,149:1004-1009.
15.董钰明. 药物分析学. 北京：清华大学出版社，2018
16.Xiali Ding, Jing Yang，Yuming Dong*,Advancements in the preparation of high-performance liquid chromatographic organic polymer monoliths for the separation of small-molecule drugs, Journal of Pharmaceutical Analysis,2018,8:75-95.
17.Xie Yunfei, Luo Tian, Yang Jing, Yuming Dong*. Rapid determination of amino acids in beer, red wine, and donkey-hide gelatin by gradient elution of HPLC: from micellar liquid Chromatography to high submicellar liquid chromatography.[J]. Journal of Aoac International, 2018.101（1）：249-255.
18.TianLuo， Yue Dong，Shujuan He，Jing Yang，Yuming Dong*.Establishing a sensitive capillary electrophoresis-UV method for direct determination of amino acids to evaluate vinegar quality, Electrophoresis, 2018, 39(11), 1410–1416.
19.Tian Luo，Yunfei Xie，Yue Dong，Aihui Liub，Yuming Dong*. Quality assessment of soy sauce using underivatized amino acids by capillary electrophoresis, International Journal of Food Properties,2017,20(S3):S3052-S306.
20.Tian Luo, Jing Ke, Yunfei Jie, Yuming Dong*. Determination of underivatized amino acids to evaluate quality of beer by capillary electrophoresis with online sweeping technique. Journal of Food and Drug Analysis. 2017,25(4):789-797.
21.Qiong An, Yuming Dong*, Ningwei Lu, Ning Li. A micellar liquid chromatographic method for the determination of ephedrine and pseudoephedrine in human serum by direct inject the sample with simple dilution. Journal of liquid Chromatography & Related technology.2017,40(4):177-183
22.Jing Ke, Yuming Dong,* Tian Luo, Yunfei Xie, Development of a gradient micellar liquid chromatographic method eluting from micellar mode to high submicellar mode for the rapid separation of free amino acids?. Analytical Methods, 2017,9, 1762 – 1770.
23.Guoning Chen, Ning Li,Tian Luo,Yuming Dong*. Enantiomers recognition of propranolol based on organic–inorganic hybrid open-tubular MIPs-CEC column using 3-(trimethoxy silane) propyl methacrylate as a cross-linking monomer, Journal of Chromatographic Science,2017, 55(4):471-479.
24.Jing Ke, Hanfei Dou , Ximin Zhang, Dushimabararezi Serge Uhagaze, Xiali Ding, Yuming Dong*，Determination of pKa values of alendronate sodium in aqueous solution by piecewise linear regression based on acid-base potentiometric titration, Journal of Pharmaceutical Analysis，2016,6（6）：404-409.
25.Yu-Ming Dong*, Qiong An, Ning-Wei Lu, Ning Li, Development micellar HPLC method for simultaneous determination of ephedrine, pseudoephedrine, and methylephedrine in ephedra herb and traditional Chinese medicinal preparations, Acta Chromatographica, 2015,27(2):355-372.
26.Ning-wei Lu, Ning Li，Yu-ming Dong*. A Rapid hydrophilic interaction liquid chromatographic method for simultaneous determination of three ephedrine alkaloids in ephedra herb and its preparations，Journal of Liquid Chromatography& Its. Relatated. Technology，2015，38（15）：1507-1514.
27.Ning Li, Chun-lan Li, Ning-wei Lu, Yu-ming Dong*, A novel micellar per aqueous liquid chromatographic method for simultaneous determination of diltiazem hydrochloride, metoprololtartrate and isosorbide mononitrate in human serum, Journal of Chromatography B, 2014 (967) 90–97.
28.Ning Li, Ningwei Lu, Jing Ke and Yu-ming Dong*,. Micellar per aqueous liquid chromatography: analternative to micellar liquid chromatography for determination of polar compounds? .Analytical. Methods, 2014 (6) 7426-7435.
29.Yu-ming Dong*, Ning Li, Qiong An, Ning-wei Lu. A novel nonionic micellar liquid chromatographic method for simultaneous determination of pseudoephedrine, paracetamol and chlorpheniramine in cold compound preparations. Journal of Liquid Chromatography & Its. Relatated. Technology, 2014,10（2）： 251-258
30.Yuming Dong*，Zhengjie Zhou, Hongyan Ding, Preparation and properties of a pH sensitive carrier based on three kinds of polymer blend to control the release of 5-amino salicylic acid，Pharmacetical Development and Technology, 2014,19(8): 960–967.
31.Ningwei Lu, Qiong An，Ning Li，Yuming Dong,* RP-HPLC Method Using One Marker for Quantification of Four Podophyllum Lignans in Medicinal Plants，Journal of Chromatographic Science，2013,4(8),1-6.
32.Ningwei Lu, Wenxiang Zhang, Qiong An, Ning Li, and Yuming Dong*, Two-Dimensional Thin-Layer Chromatographic Fingerprint of Helleborus thibetanus Franch. Using a Polyamide Plate with Nonaqueous and Reversed Micellar Mobile Phases, Journal of Planar Chromatography-Modern TLC, 2013, 26(6):463-469.
33.Yuming Dong*,Ningwei Lu,Richard B. Cole,Analysis of the volatile organic compounds in Cinnamomum cassiabark by direct sample introduction thermal desorption gas chromatography–mass spectrometry, Journal of Essential Oil Research, 2013, 25(6):458-463.
34.Qiong An, Ningwei Lu and Yuming Dong*, Chromatographic fingerprint coupled with hierarchical clustering analysis and principal component analysis for quality evaluation and original discrimination of rhizomes of Helleborus thibetanus Franch by HPLC-DAD, Analytical Methods, 2013,5（20）, 5775–5784.
35.Yu-Ming Dong，Kun-Yi Chien,Jeng-Ting CheShih-Jie Lin,Tzu-Chien V. Wang,Jau-Song Yu*，Site-specific separation and detection of phosphopeptide isomers with pH-mediated stacking capillary electrophoresis-electrospray ionization-tandem mass spectrometry，Journal of Separation Science, 2013,36（9-10）： 1582-1589.
36.安琼，路宁维，董钰明*，高等医药院校实验教学存在的问题及对策探讨，卫生职业教育，2012，30（17）：106-107.
37.Adireddy Shiva, Cuikun Lin, Palshin Vadim, Yuming Dong, Cole Richard*, Caruntu Gabriel, Size-controlled synthesis of quasi-monodisperse transition-metal Ferrite nanocrystals in fatty alcohol solutions, Journal of Physical Chemistry. C, 2009(3), 113: 20800-20811.
38.Yuming Dong, Yann-Lii Leu, Kun-Yi Chie, Jau-Song Yu*, Separation anddetermination of low abundant flavonoids in scutellaria baicalensis georgi by micellar electrokinetic capillary electrophoresis, Analytical Letters, 2009 ,42(10):1444-1457.
39.Leizhou, Shuming Wang, Kan Tian,Yuming Dong, Zhide Hu*, Simultaneous determination of catecholamines and amino acids by micellar electrokinetic chromatography with laser-induced fluorescence detection, Journal of Separation Science,2007,30(1):110-117.
40.Yuming Dong, Hongli Chen, Yonglei Chen, Yang Hui, Xingguo Chen*, Zhide Hu，Separation and determination of epinephrine and dopamine in traditional Chinese medicines and human plasma by micellar electrokinetic chromatography with laser induced fluorescence detection，Journal of Separation Science, 2006, 29(13): 2049-2055.
41.Yuming Dong, Yonglei Chen, Xingguo Chen*, Zhide Hu, Method for derivatization of ephedrine and pseudoephedrine in nonaqueous media and determination by nonaqueous capillary electrophoresis with laser induced fluorescence detection， Biomedical Chromatography, 2006, 20(11)：1150-1156.
42.Yuming Dong, Xingguo Chen*, Zhide Hu, Derivatization of hydrophobic amino acids in nonaqueous media and separation by nonaqueous capillary electrophoresis with laser induced fluorescence detection, Microchimica Acta, 2006,154(3-4): 281-286.
43.Ning Lian, Xijun Chang*, Hong Zheng, Sui Wang, Yuming Dong, Shoujun Lai, Synthesis and efficiency of a chelating fiber for preconcentration and separation of trace Au(III) and Pd (IV) from solution samples, Annali di Chimica, 2005, 95(9-10):677-683.
44.Hong Zheng, Xijun Chang*, Ning Lian, Jie Mao, Sui Wang, Yuming Dong, Synthesis and application of a novel poly(acryl-p-toluenesulfonamideamidine-p-toluenesulfonylamide) chelating fiber for preconcentration and separation of trace noble metal ions from solution samples, Microchimica Acta, 2005，149（3-4）：259-266.
45.Yuming Dong, Xiaofeng Chen, Yonglei Chen, Xingguo Chen*, Zhide Hu, Separation and determination of pseudoephedrine, dextromethorphan, diphenhydramine and chlorpheniramine in cold medicines by nonaqueous capillary electrophoresis, Journal of Pharmaceutical and Biomeidical Analysis, 2005, 39(1-2): 285-289.
46.董钰明，冯葳，段生玉*，药学专业分析化学与药物分析的关系，兰州医学院学报，2001,27（4）：77-78.

【1】2014年主持横向科研项目：化学药品阿仑磷酸钠肠溶滴丸研究，编号（)；横向科研项目：八味接骨丸舒气安神丸，项目编号(432367)。
【2】2016年主持横向项目：枸杞多糖质量标准及掺假分析方法研，项目编号()。
【3】2017年主持横向项目：麝香祛风湿油质量标准提升研究，项目编号 ()；横向项目：岷县红车轴花茶的前期开发，项目编号()；横向项目：红参川贝咳喘丸项目，项目编号()；横向项目：生地消渴丸项目，项目编号()；主持开放基金：Fe3O4纳米粒子“阀门”对介孔硅材料内药物的可控释放及其MRI研究，项目编号（）。