基本情况
姓名：李苏华
性别：男
出生年月：1983-05
籍贯：江苏姜堰 （江西德安人）
职位：教授，博士生导师
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联系方式
电话：暂未填写
传真：暂未填写
邮箱：lisuhua5@mail.sysu.edu.cn
通讯地址：广州市海珠区新港西路135号中山大学化学学院丰盛堂B522
邮编：510275
个人网站：暂未填写
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教育经历
2007.09–2012.07 ?中国科学院上海有机化学研究所，有机化学博士 ? ?导师：麻生明 院士
2002.09–2006.06 ?南京大学 ?化学学士学位
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工作经历
2017.07–至今 ? ?????中山大学化学学院，教授，博士生导师
2014.07–2017.06 ?The Scripps Research Institute 博士后 ?合作导师：K. Barry Sharpless教授
2012.08–2014.07 ?The Scripps Research Institute 博士后 ?合作导师：Jin-Quan Yu教授
2006.08–2007.09 ?康化（上海）新药研发有限公司
讲授课程
暂无
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科研方向
通过研究新型化学试剂来发展经济高效的合成方法学，并探索其在能源、环境、材料以及生物中的应用。
课题组长期招聘正、副特聘研究员与博士后。我们热诚欢迎硕士和博士研究生加入本课题组，同时欢迎本科生利用课余时间来本组短期或长期交流学习
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科研项目
中山大学“****”启动经费
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获奖情况
· ? ? ? ?2011年度麻生明小组“研究贡献奖”, 2012
· ? ? ? ?布劳恩奖学金, 布劳恩惰性气体系统有限公司, 2011
· ? ? ? ?中国科学院院长优秀奖, 2011
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论著一览
(1) ? ? Wan Jung Kim, Keith Korthals, Suhua Li, Christine Le, Jaroslaw Kalisiak, K. Barry Sharpless, Valery V. Fokin, Yukiko Miyamoto, Lars Eckmann*, Click chemistry-facilitated structural diversification of nitrothiazoles, nitrofurans and nitropyrroles enhances antimicrobial activity against Giardia lamblia, Antimicrob. Agents Chemother. 2017, 61, e02397-16.
(2) ? ? Bukeyan Miao, Yangguangyan Zheng, Penglin Wu, Suhua Li, Shengming Ma*, Bis(cycloocta- 1,5-diene)nickel-Catalyzed Carbon Dioxide Fixation for Stereoselective Synthesis of 3-Alkylidene-2-indolinones, Adv. Synth. Catal. 2017, 359, 1691.
(3) ? ? Suhua Li, Peng Wu, John E. Moses, K. Barry Sharpless*, Multidimensional SuFEx Click Chemistry: Sequential Sulfur(VI) Fluoride Exchange Connections of Diverse Modules Launched From An SOF4 Hub, Angew. Chem. Int. Ed. 2017, 56, 2903. (VIP文章, highlighted in C&E News, 2017, 95, 10; Chemistry World: https://www.chemistryworld.com/news/sulfur-linkage-takes-click-chemistry-in-a-different-direction/**.article)
(4) ? ? Haiyan Fu, Peng-Xiang Shen, Jian He, Fanglin Zhang, Suhua Li, Peng Wang, Tao Liu, Jin-Quan Yu*, Ligand-Enabled Alkynylation of C(sp3)-H Bonds with Pd(II) Catalysts, Angew. Chem. Int. Ed. 2017, 56, 1873.
(5) ? ? Wentao Chen?, Jiajia Dong?, Lars Plate?, David E. Mortenson, Gabriel J. Brighty, Suhua Li, Yu Liu, Andrea Galmozzi, Peter S. Lee, Jonathan J. Hulce, Benjamin F. Cravatt, Enrique Saez, Evan T. Powers, Ian A. Wilson, K. Barry Sharpless*, Jeffery W. Kelly*, Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue, J. Am. Chem. Soc. 2016, 138, 7353.
(6) ? ? Bukeyan Miao, Suhua Li, Gen Li and Shengming Ma*, Cyclic Anti-Azacarboxylation of 2?Alkynylanilines with Carbon Dioxide, Org. Lett. 2016, 18, 2556. (Highlighted in Synfacts, 2016, 12, 890.)
(7) ? ? Suhua Li, Ru-Yi Zhu, Kai-Jiong Xiao and Jin-Quan Yu*, Ligand-Enabled Arylation of γ-C-H Bonds, Angew. Chem. Int. Ed. 2016, 55, 4317.
(8) ? ? Enxuan Zhang*, Jiaze Tang, Suhua Li, Peng Wu, John E. Moses and K. Barry Sharpless*, Chemoselective Synthesis of Polysubstituted Pyridines From Heteroaryl Fluorosulfates, Chem. Eur. J. 2016, 22, 5692. (Highlighted in Synfacts, 2016, 12, 617.)
(9) ? ? Wentao Chen?, Jiajia Dong?, Suhua Li, Yu Liu, Yujia Wang, Leonard Yoon, Peng Wu, K. Barry Sharpless*, Jeffery W. Kelly*, Synthesis of Sulfotyrosine-Containing Peptides by Incorporating Fluorosulfated Tyrosine Using an Fmoc-Based Solid-Phase Strategy, Angew. Chem. Int. Ed. 2016, 55, 1835.
(10) ?Ru-Yi Zhu, Keita Tanaka, Gen-Cheng Li, Jian He, Hai-Yan Fu, Suhua Li and Jin-Quan Yu*, Ligand-Enabled Stereoselective β-C(sp3)–H Fluorination: Synthesis of Unnatural Enantiopure anti-β-Fluoro-α-amino Acids, J. Am. Chem. Soc. 2015, 137, 7067.
(11) ?Xiao-Chen Wang, Wei Gong, Li-Zhen Fang, Ru-Yi Zhu, Suhua Li, Keary M. Engle and Jin-Quan Yu*, Ligand-enabled meta-CH activation using a transient mediator, Nature, 2015, 519, 334.
(12) ?Gang Chen, Toshihiko Shigenari, Pankaj Jain, Zhipeng Zhang, Zhong Jin, Jian He, Suhua Li, Claudio Mapelli, Michael M. Miller, Michael A. Poss, Paul M. Scola, Kap-Sun Yeung and Jin-Quan Yu*, Ligand-Enabled beta-C-H Arylation of alpha-Amino Acids Using a Simple and Practical Auxiliary, J. Am. Chem. Soc. 2015, 137, 3338.
(13) ?Suhua Li, Gang Chen, Chen-Guo Feng, Wei Gong and Jin-Quan Yu*, Ligand-Enabled γ-C–H Olefination and Carbonylation: Construction of β-Quaternary Carbon Centers, J. Am. Chem. Soc. 2014, 136, 5267. (Highlighted in Organic Chemistry Portal, 2015, Jan 26th: http://www.organic-chemistry.org/Highlights/2015/26January.shtm)
(14) ?Jian He?, Suhua Li?, Youqian Deng, Haiyan Fu, Brian N. Laforteza, Jillian E. Spangler, Anna Homs and Jin-Quan Yu*, Ligand-Controlled C(sp3)–H Arylation and Olefination in Synthesis of Unnatural Chiral α–Amino Acids, Science, 2014, 343, 1216. (Highlighted in C&EN News, 2014, 92, 5. ?共同第一作者.)
(15) ?Chen-Guo Feng, Mengchun Ye, Kai-Jiong Xiao, Suhua Li and Jin-Quan Yu*, Pd(II)-Catalyzed Phosphorylation of Aryl C-H Bonds, J. Am. Chem. Soc. 2013, 135, 9322.
(16) ?Suhua Li, Juntao Ye, Weiming Yuan and Shengming Ma*, Highly Regioselective Three-component Palladium-Catalyzed Synthesis of 5-Vinyloxazolidin-2-one from 2,3-Allenyl Amines, Organic Iodides and Carbon Dioxide, Tetrahedron, 2013, 69, 10450.
(17) ?Juntao Ye, Suhua Li and Shengming Ma*, Gorlos-phos: Addressing the Stereoselectivity in Palladium-catalyzed Exo-mode Cyclization of Allenes with a Nucleophilic Functionality, Org. Biomol. Chem. 2013, 11, 5370.
(18) ?Suhua Li, Bukeyan, Miao, Weiming Yuan and Shengming Ma* Carbometalation–Carboxylation of 2,3-Allenols with Carbon Dioxide: A Dramatic Effect of Halide Anion, Org. Lett., 2013, 15, 977. (Highlighted in Organic Chemistry Portal, Abstracts: http://www.organic-chemistry.org/abstracts/lit3/945.shtm)
(19) ?Juntao Ye, Suhua Li and Shengming Ma*, Palladium-Catalyzed Cyclization Reactions of 2,3-Allenyl Amines with Propargylic Carbonates,Org. Lett. 2012, 14, 2312.
(20) ?Suhua Li and Shengming Ma*, Quadri-Synergetic Effect for Highly Effective Carbon Dioxide Fixation and Its Application to Indoloquinolinone. Adv. Synth. Catal. 2012, 354, 2387.
(21) ?Juntao Ye, Suhua Li, Bo Chen, Wu Fan, Jingqiang Kuang, Jinxian Liu, Yu Liu, Bukeyan Miao, Bao Wan, Yuli Wang, Xi Xie, Qiong Yu, Weiming Yuan and Shengming, Ma*, Catalytic Asymmetric Synthesis of Optically Active Allenes from Terminal Alkynes,Org. Lett., 2012, 14, 1346.
(22) ?Suhua Li and Shengming Ma*, CO2-Activation for γ-Butyrolactones and its Application in the Total Synthesis of (±)-Heteroplexisolide E, Chem. Asian J. 2012, 7, 2411.
(23) ?Suhua Li and Shengming Ma*, Highly Selective Nickel-Catalyzed Methyl-Carboxylation of Homopropargylic Alcohols for α-Alkylidene-γ-butyrolactones. Org. Lett. 2011, 13, 6046. (Highlighted in Synfacts, 2012, 8, 196.)
(24) ?Suhua Li, Weiming Yuan and Shengming Ma*, Highly Regio- and Stereoselective Three-Component Nickel-Catalyzed syn-Hydrocarboxylation of Alkynes with Diethyl Zinc and Carbon Dioxide, Angew. Chem. Int. Ed. 2011, 50, 2578. (Highlighted in Nature China doi: 10.1038/nchina.2011.13; Angew. Chem. Int. Ed. 2011, 50, 6210.)
(25) ?Shengming Ma*, Jinxian Liu, Suhua Li, Bo Chen, Jiajia Cheng, Jinqiang Kuan, Yu Liu, Baoqiang Wan, Yuli Wang, Juntao Ye, Qiong Yu, Weiming Yuan and Shichao Yu, Development of a General and Practical Iron Nitrate/TEMPO Catalyzed Aerobic Oxidation of Alcohols to Aldehydes/Ketones: Catalysis with Table Salt, Adv. Synth. Catal. 2011, 353, 1005.
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相关成果
首次实现了炔烃与CO-2的氢羧化反应；发展了两个高效的喹啉类配体,并由Sigma-Aldrich公司将之商品化，命名为Li-Quinoline和Li-Yu t-Butyl Quinoline；将点击化学发展到一个全新的维度，实现了三维连接。在国际著名刊物上发表学术论文25篇，其中第一作者10篇，包括1篇Science (共同第一作者)，1篇J. Am. Chem. Soc., 3篇Angew. Chem. Int. Ed.，他引数已超过700次。