性 ? ?别： 女?? ?
导 ? ?师： 博士导师,硕士导师
学科专业： 免疫学?? ?
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个人简介：
? ? 2002年获微生物学博士学位；2002－2004年，于美国弗吉尼亚州立大学（VCU）接受博士后培训；2005－2008年，在美国加利福尼亚大学（UCSB）任研究助理。2009年作为“****”引进人才，受聘于中山大学中山医学院。研究方向是宿主细胞与登革病毒之间的相互作用，及细胞抗病毒感染的固有免疫应答调控机制。
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重要学术研究成果与贡献：
学术论著与教材：
1. ? ? ? ?Xiaoyan Chen, Jun Xia, Qirui Zhao, Yi Wang, Jingyu Liu, Lianqiang Feng, Junfang He*, Ping Zhang*. Eukaryotic initiation factor 4AI interacts with NS4A of Dengue virus and plays an antiviral role. Biochemical and Biophysical Research Communications, 2015, 461 (2015): 148-153
2. ? ? ? ?Yuye Li, Siyu Wu, Jieying Pu, Xi Huang, Ping Zhang*. Dengue Virus Upregulates Expression of Notch Ligands Dll1 and Dll4 Through IFN-β Signaling Pathway. Immunology, 2015, 144(1):127-38
3. ? ? ? ?Peifen Zhang#, Yuye Li#, ?Jun Xia, Junfang He, Jieying Pu, Jiong Xie, Siyu Wu, Lianqiang Feng, Xi Huang, Ping Zhang*. IPS-1 plays an essential role in dsRNA-induced stress granule formation by interacting with PKR and promoting its activation. Journal of Cell Science, 2014, 127: 2471-2482
4. ? ? ? ?Siyu Wu, Li He, Yuye Li, Tinglong Wang, Lianqiang Feng, Lifang Jiang, Ping Zhang*, Xi Huang*. miR-146a facilitates replication of dengue virus by dampening interferon induction by targeting TRAF6. Journal of Infection. 2013, 67, ( 4): 329–341
5. ? ? ? ?Yuye Li, Jiong Xie, Siyu Wu, Jun Xia, Peifen Zhang, Chao Liu, Ping Zhang*, Xi Huang*. Protein Kinase Regulated by dsRNA Downregulates the Interferon Production in Dengue Virus- and dsRNA-stimulated Human Lung Epithelial Cells. PLoS One. 2013, 8(1):e55108
6. ? ? ? ?Ping Zhang，Siyu Wu, Lietao Li, Zhaoduan Liang , Yuye Li, Lianqiang Feng, Xi Huang*. Adjuvant PIKA protects hepatoma cells from dengue virus infection by promoting TBK-1 dependent innate immune response. Archives of Virology, 2013, 158(4):829-38
7. ? ? ? ?Zhaoduan Liang, Siyu Wu, Yuye Li, Li He, Minhao Wu, Lifang Jiang, Lianqiang Feng, Ping Zhang*, Xi Huang*. Activation of Toll-Like Receptor 3 Impairs the Dengue Virus Serotype 2 Replication through Induction of IFN-b in Cultured Hepatoma Cells. PLoS One. 2011, 6(8):e23346
8. ? ? ? ?Minhao Wu, Anping Peng, Mingxia Sun, Qiuchan Deng, Linda D. Hazlett, Jin Yuan, Xialin Liu, Qianying Gao, Lianqiang Feng, Junfang He, Ping Zhang*, Xi Huang*. TREM-1 Amplifies Corneal Inflammation after Pseudomonas aeruginosa Infection by Modulating Toll-Like Receptor Signaling and Th1/Th2-Type Immune Responses. Infection and Immunity. 2011, 79(7):2709-16.
9. ? ? ? ?Ping Zhang, Jeffrey Langland, Bertram Jacobs, Charles Samuel*. Protein Kinase PKR-Dependent Activation of Mitogen-Activated Protein Kinases Occurs through Mitochondrial Adapter IPS-1 and Is Antagonized by Vaccinia Virus E3L. Journal of Virology, 2009, 83: 5718-5725. ?
10. ? ?Ping Zhang, Charles Samuel*. Induction of protein kinase PKR-dependent activation of interferon regulatory factor 3 by vaccinia virus occurs through adapter IPS-1 signaling. Journal of Biological Chemistry, 2008, 283: 34580-34587.
11. ? ?Ping Zhang, Bertram Jacobs，Charles Samuel*. Loss of protein kinase PKR expression in human cells complements the vaccinia virus E3L deletion mutant phenotype by restoration of viral protein synthesis. Journal of Virology, 2008, 82: 840-848.
12. ? ?Ping Zhang, Charles Samuel*. Protein Kinase PKR Plays a Stimulus- and Virus-dependent Role in Apoptotic Death and Virus Multiplication in Human Cells. Journal of Virology, 2007, 81: 8192-8200.
13. ? ?Christopher McAllister, Ann Toth, Ping Zhang, Patricia Devaux, Roberto Cattaneo, Charles E. Samuel*. ?Mechanisms of Protein Kinase PKR-Mediated Amplification of Beta Interferon Induction by C Protein-Deficient Measles Virus. Journal of Virology, 2010, 84(1):380-386.
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学术兼职：
American Society for Virology 会员
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科研项目研究课题：
1. ?Notch受登革病毒调控的分子机制及其对固有免疫和病毒复制的影响： 张萍
负责人：张萍 参与人： 经费：70.0000 万元 年份：2013
2. ?PKR在登革病毒固有免疫中的调控作用： 张萍
负责人：张萍 参与人： 经费：30.0000 万元 年份：2012
3. ?PKR在登革病毒诱导干扰素合成过程中的调控作用与分子机制： 张萍
负责人：张萍 参与人： 经费：58.0000 万元 年份：2011
4. ?广州管圆线虫病的免疫调节机制研究： 张萍
负责人：张萍 参与人： 经费：35.0000 万元 年份：2009
5. ?与PKR相互作用的先天免疫调控蛋白的鉴定和功能分析： 张萍
负责人：张萍 参与人： 经费：5.0000 万元 年份：2009
6. ?与 PKR相互作用的先天免疫相关蛋白的鉴定和功能分析： 张萍
负责人：张萍 参与人： 经费：23.0000 万元 年份：2009
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