陈裕明 教授

流行病学系




办公电话



电子邮件
chenyum@mail.sysu.edu.cn



学术简历
医学博士（香港中文大学）
医学硕士（华中科技大学，原同济医科大学）
预防医学学士（中南大学，原湖南医科大学）
　　香港中文大学博士，中山大学统流系流行病学方向教授，兼任广东省营养学会副理事长、中国营养学会理事、中华预防医学会科技奖评审委员会委员等。教育部“新世纪优秀人才计划”获得者。主持国家自然科学基金面上项目5项，中山大学5010（50项10年）项目，以及其他课题多项。在JCEM, Am J Epidemiol, Am J Clin Nutr, Heart, Br J Cancer, Osteoporos Int, Bone, Int J Obes, Sci Rep, Int J Cardiol，Diabetes Care，Microbiome等国际著名期刊发表SCI论文共170余篇（被SCI论文引用5300余次），其中第一或通信作者论文90余篇。主要研究方向为营养膳食等暴露因素与代谢性疾病（骨质疏松、动脉硬化、代谢综合征、脂肪肝、肥胖及少肌症等）的流行病学研究。?
社会兼职
1.?中国营养学会 理事
2.?广东省营养学会 副理事长
3.?中国营养学会 社区营养与健康管理分会 副主任委员
4.?中国营养学会 营养流行病分会 副主任委员
5.?广东省营养学会 社区营养与慢病管理专业委员会 副主任委员
6.?广东省营养学会 妇幼专业委员会 副主任委员

主要承担或参与的课题（5-6项代表性课题）
1. 中老年人血液维生素D适宜水平研究. 国家自然科学基金，批准年月：2017.8；批准号：**, 60万；主持人
2.?膳食、血浆及红细胞脂肪酸与中老年人动脉粥样硬化关系的6年前瞻性研究.国家自然科学基金，2014.8；No. **；主持人
3.?膳食模式、炎性因子、氧化应激及其相关基因对中老年居民骨质疏松影响的前瞻性研究。国家自然科学基金，2012.8；No. **, 主持人。
4.?膳食抗氧化剂、抗氧化酶、氧化应激及相关基因对妇女髋骨骨折的交互作用。国家自然科学基金，2010.8；No. **；主持人
5. 候选基因及膳食模式对妇女髋骨骨折的交互作用。国家自然科学基金，2008.9，No. **，主持人
6?营养膳食及基因多态性对动脉粥样硬化影响的前瞻性研究。国家自然科学基金 重点项目， 2011.9；No. **. 第二
7.?青少年、哺乳期妇女、绝经期妇女钙需要量研究。国家十一五支撑项目“我国重点人群铁、钙需要和膳食应用研究（No. 2008BAI58B02）”分题。批准年月：2008.11，起止年月，2009.1-2010.12。
8.?常见慢病的患病与发病趋势及其影响因素的前瞻性研究。中山大学“临床医学研究5010计划”。No.**；2007.11-2015.10。主持人
9. 托菲尔婴儿配方奶粉和金领冠呵护婴儿配方奶粉的临床喂养效果研究。内蒙古伊利集团公司。2015.9~2017.12. 主持人
10. KMS卫生巾/护垫使用效果研究。广东景兴卫生用品有限公司。2013.10~2016.10，主持人
11.?奶及其制品摄入量对中老年人骨流失影响的前瞻性研究.中国营养学会营养科研基金—伊利营养与健康研究基金. 2014.2；主持人。
12. 餐饮行为及膳食模式对中老年社区居民动脉粥样硬化剂及代谢综合征影响的前瞻性研究. 中国红十字会--中国肯德基餐饮健康基金。 2013.12，主持人。
13. 中老年妇女骨质疏松相关膳食模式与膳食质量指数研究。 达能营养科学基金。2012.12，主持人。

近期发表的主要文章，? * 通信作者
1. ? Xu FZ#, Fu YQ#, Sun TY, Jiang ZL, Miao ZL, Shuai ML, Gou WL, Ling CW, Jian Yang, Wang J*, Chen YM *, Zheng JS*. The interplay between host genetics and the gut microbiome reveals common and distinct microbiome features for human complex diseases. Microbiome Accepted 2020.Sept.08.
2.??? Meng Liu, Luo-shi-yuan Zuo, Ting-yu Sun, Yan-Yan Wu, Yu-ping Liu, Fang-fang Zeng, Chen YM *. Circulating Very-Long-Chain Saturated Fatty Acids Were Inversely Associated with Cardiovascular Health: A Prospective Cohort Study and Meta-Analysis. Nutrients 2020 Sept. 4, 12, 2709; doi:10.3390/nu**.
3.??? Yun-yang Deng#, Yu-ping Liu#, Chu-wen Ling, Yi-hong Li, Yan-Yan Wu, Yue-bin Ke*, Chen YM *.? Higher healthy lifestyle score associated with greater bone mineral density in middle-aged and elderly Chinese adults. Arch Osteoporosis 2020 Aug 17;15(1):129. doi: 10.1007/s11657-020-00758-9.
4.??? Zhong QW#, Wu YY#, Xiong F, Liu M， Liu YP, Wang C,? Chen YM*.? Higher flavonoid intake is associated with a lower progression risk of non-alcoholic fatty liver disease in adults: a prospective study.? Br J Nutr. 2020 Jul 27;1-32. doi: 10.1017/S00071**
5.??? Zelei Miao#, Jie-sheng Lin#, Yingying Mao#, Geng-dong Chen, Fang-fang Zeng, Hong-li Dong, Zengliang Jiang, Jiali Wang, Congmei Xiao, Menglei Shuai, Wanglong Gou, Yuanqing Fu, Fumiaki Imamura, Nita Forouhi, Chen YM*, Ju-Sheng Zheng*. Erythrocyte n-6 polyunsaturated fatty acids, gut microbiota and incident type 2 diabetes: a prospective cohort study. Diabetes Care 2020 Jul 28;dc200631.? doi: 10.2337/dc20-0631.
6.??? Li YH#, Sun TY#, Wu YY, Li CF, Ling CY, Zeng FF, Chen YM*. Higher erythrocyte n-3 polyunsaturated fatty acid were associated with a better profile of DXA-derived body fat and fat distribution in adults. Int J Obes 2020 Mar 17. doi: 10.1038/s41366-020-0569-8.
7.??? Ding D#, Li YH#, Xiao ML, Dong HL, Lin JS, Chen GD, Chen ZY, Tang XY*, Chen YM*. Erythrocyte Membrane Polyunsaturated Fatty Acids Are Associated with Incidence of Metabolic Syndrome in Middle-Aged and Elderly People-An 8.8-Year Prospective Study. J Nutr 2020 Mar 13. pii: nxaa039. doi: 10.1093/jn/nxaa039.
8.??? Ding D#, Zhong QW#, Zuoluo SY, Ling CW, Xiong F, Ke YB*, Chen YM*. Association between erythrocyte membrane n-3 and n-6 polyunsaturated fatty acids and carotid atherosclerosis: A prospective study. Atherosclerosis. 2020 Apr;298:7-13. doi: 10.1016/j.atherosclerosis.2020.02.013.
9.??? Wang C#, Ling CW#, Ding D, Li YH, Cao WT, Tang XY*, Chen YM*. Associations of Serum Carotenoids with DXA-Derived Body Fat and Fat Distribution in Chinese Adults: A Prospective Study. J Acad Nutr Diet. 2020 Mar 4. doi: 10.1016/j.jand.2019.12.010.
10.? Dong HL#, Tang XY#, Deng YY, Zhong QW, Wang C, Zhang ZQ*, Chen YM*. Urinary equol, but not daidzein and genistein, was inversely associated with the risk of type 2 diabetes in Chinese adults. Eur J Nutr. 2020 Mar;59(2):719-728.
11.? Chen ZY#, Liu M#, Jing LP, Xiao ML, Dong HL, Chen GD, Chen YM*. Erythrocyte membrane n-3 polyunsaturated fatty acids are inversely associated with the presence and progression of nonalcoholic fatty liver disease in Chinese adults: a prospective study. Eur J Nutr. 2020 Apr;59(3):941-951.
12.? Wang X, Xie J, Pang J, Zhang H, Chen X, Lin J, Li Q, Chen Q, Ma J, Xu X, Yang Y, Ling W*, Chen Y*. Serum SHBG is associated with the development and regression of non-alcoholic fatty liver disease: a prospective study. J Clin Endocrinol Metab. 2020 Mar 1;105(3):dgz244. doi: 10.1210/clinem/dgz244. pii: dgz244.
13.? Zeng FF, Chen ZY, Zheng JS, Lin JS, Li YH, Qiu R, Wang C, Sun LL, Chen YM*. Association between erythrocyte fatty acids in de novo lipogenesis pathway and DXA-derived body fat and trunk fat distribution in Chinese adults: a prospective study. Eur J Nutr. 2019 Dec;58(8):3229-3239.
14.? Zheng JS#*, Lin JS#, Dong HL, Zeng FF, Li D, Song Y, Chen YM*. Association of erythrocyte n-3 polyunsaturated fatty acids with incident type 2 diabetes in a Chinese population. Clin Nutr. 2019 Oct;38(5):2195-2201.
15.? Xiao ML#, Chen GD#, Zeng FF, Qiu R, Shi WQ, Lin JS, Cao Y, Ling WH, Chen YM*. Higher serum carotenoids associated with favorable progression of non-alcoholic fatty liver disease in adults: a prospective study. Eur J Nutr 2019 Mar;58(2):721-730.
16.? Lin JS, Dong HL, Chen GD, Chen ZY, Dong XW, Zheng JS,? Chen YM*. Erythrocyte saturated fatty acids and incident type 2 diabetes in Chinese men and women: the Guangzhou Nutrition and Health Study. Nutrients 2018 Oct 1;10(10).
17.? Liao J, Muniz-Terrera G, Scholes S, Hao Y, Chen YM*. Lifestyle index for mortality prediction using multiple ageing cohorts in the USA, UK and Europe. Sci Rep? 2018 Apr 27;8(1):6644.
18.? Cao WT#, Zeng FF#, Li BL#, Lin JS, Liang YY*, Chen YM*. Higher dietary carotenoid intake associated with lower risk of hip fracture in elderly Chinese: A 1070 pairs of case-control study. Bone 2018 Jun;111:116-122.
19.? Wang C#, Qiu R#, Cao Y, Ouyang WF, Li HB, Ling WH, Chen YM*. Higher dietary and serum carotenoid levels are associated with lower carotid intima–media thickness in middle-aged and elderly people. Br J Nutr 2018 Mar;119(5):590-598.
20.? Jing LP, Xiao ML, Dong HL, Lin JS, Chen GD, Ling WH,? Chen YM*. Serum carotenoids are inversely associated with RBP4 and other inflammatory markers in middle-aged and elderly adults. Nutrients, 2018 Feb 25, 10, 260; doi:10.3390/nu**.
21.? Tian HY#, Qiu R#, Jing LP, Chen ZY, Chen GD, Chen YM*. Alternate Mediterranean diet score is positively associated with skeletal muscle mass index in middle-aged adults. Br J Nutr. 2017 Apr;117(8):1181-1188.
22.? Zhang ZQ, Cao WT, Shivappam N, Hebert JR, Li BL, He J, Tang XY, Liang YY, Chen YM*. Association between Diet inflammatory index and osteoporotic hip fracture in elderly Chinese population. J Am Med Dir Assoc 2017 Aug 1;18(8):671-677.
23.? Chen GD#, Ding D#, Tian HY, Zhu YY, Cao WT, Wang C, Chen YM*. Adherence to the 2006 American Heart Association's Diet and Lifestyle Recommendations for cardiovascular disease risk reduction is associated with bone mineral density in older Chinese. ?Osteoporos Int 2017 Apr;28(4):1295-1303.
24.? Cao WT#, He J#, Chen GD, Wang C, Qiu R, Chen YM*. The association between urinary sodium to potassium ratio and bone density in middle-aged Chinese adults.? Osteoporos Int 2017 Mar;28(3):1077-1086.
25.? Chen XC#, Shen TR#, Li Q, Chen X, Li YP, Li D, Chen GD, Ling WH*, Chen YM*. Retinol Binding Protein-4 Levels and Non-alcoholic Fatty Liver Disease: A community-based cross-sectional study. Sci Rep 2017.Feb.;7:45100
26.? Dai XW#, Wang C#, Xu Y, Guan K, Su YX, Chen YM*. Urinary sodium and potassium excretion and carotid atherosclerosis in Chinese men and women. Nutrients 2016 October, 8(10), 612.
27.? Chen GD#, Dong XW#, Zhu YY, Tian HY, He J, Chen YM*. Adherence to the Mediterranean diet is associated with a higher BMD in middle-aged and elderly Chinese. ?Sci Rep.2016 May 9, 6:25662.
28.? Zhang ZQ#, Cao WT#, Liu J, Cao Y, Su YX*, Chen YM*. Greater serum carotenoid concentration associated with higher bone mineral density in Chinese adults. Osteoporos Int. 2016 Apr;27(4):1593-601.
29.? Zhong W, Tang XY, Hou HY, Liora L, Yael L, Yonatan M, Fabiana BY, Wei M, Su YX*, Chen YM *.Tolerance and Efficacy of Infant Formula with High Sn-2 Palmitate in Formula- Fed Chinese Term Infants: an Open Label, Controlled Trial. J Nutr Health Food Eng 2016 Mar 15; 4(2): 00122.?
30.? Wang C#, Lin XL#, Fan YY, Liu YT, Zhang XL, Lu YK, Xu CH, Chen YM*. Diet Quality Scores and Risk of Nasopharyngeal Carcinoma in Chinese Adults: A Case-Control Study. Nutrients. 2016 Feb 25;8(3):112.?
31.? Cao Y#, Wang C#, Guan K, Xu Y, Su YX*, Chen YM*.Association of magnesium in serum and urine with carotid intima-media thickness and serum lipids in middle-aged and elderly Chinese: a community-based cross-sectional study. Eur J Nutr 2016 Feb;55(1):219-26.?
32.? Chen YM#, Liu Y#, Zhou RF, Chen XL, Wang C, Tan XY, Wang LJ, Zheng RD, Zhang HW, Ling WH, Zhu HL*. Associations of gut-flora-dependent metabolite trimethylamine-N-oxide, betaine and choline with non-alcoholic fatty liver disease in adults. Sci Rep 2016 Jan 8;6:19076.
33.? Shi WQ, Liu J, Cao Y, Zhu YY, Guan K, Chen YM*. Association of dietary and serum vitamin E with bone mineral density in middle-aged and elderly Chinese adults: A cross-sectional study. Br J Nutr. 2016 Jan;115(1):113-20. doi: 10.1017/S00071**.
34.? Zeng FF#, Liu YT #, Lin XL, Fan YY, Zhang XL, Xu CH, Chen YM*. Folate, vitamin B6, vitamin B12, and methionine intake and risk of nasopharyngeal carcinoma in Chinese adults: A matched case-control study. Br J Nutr. 2016 Jan;115(1):121-8.
35.? Cao Y, Wang C, Liu J, Liu ZM, Ling WH, Chen YM*. Greater serum carotenoid levels associated with lower prevalence of nonalcoholic fatty liver disease in Chinese adults. Sci Rep ?2015Jul, 5,12951; doi: 10.1038/srep12951.
36.? Chen GD#, Zhu YY#, Cao Y, Liu J, Shi WQ, Liu ZM, Chen YM*. Association of dietary consumption and serum levels of vitamin A and β-carotene with bone mineral density in Chinese adults. Bone. 2015 May 28, 2015; 79: 110–115. Doi: 10.1016/j.bone.2015.05.028.
37.? Chen YM#, Liu Y#, Liu YH, Wang X, Guan K, Zhu HL*. Higher serum concentrations of betaine rather than choline is associated with better profiles of DXA-derived body fat and fat distribution in Chinese adults. Int J obes 2015 Mar;39(3):465-71.
38.? Ye YB, Chen AL, Lu W, Zhuo SY, Liu J, Guan JH,Deng WP, Fang S,Li YB*,Chen YM*. Daidzein and genistein fail to improve glycemic control and insulin sensitivity in Chinese women with impaired glucose regulation: A double-blind, randomized, placebo-controlled trial. Mol Nutr Food Res 2015 Feb;59(2):240-9.
39.? Zeng FF, Sun LL, Liu YH, Xu Y, Guan K, Ling WH, Chen YM*. Higher Erythrocyte n–3 PUFAs Are Associated with Decreased Blood Pressure in Middle-Aged and Elderly Chinese Adults. J Nutr 2014 Aug;144(8):1240-6.
40.? Zeng FF, Xue WQ, Cao WT, Wu BH, Xie HL, Fan F, Zhu HL*, Chen YM*. Diet-quality scores and risk of hip fractures in elderly urban Chinese in Guangdong, China: a case–control study. Osteoporos Int 2014 Aug;25(8):2131-41.
41.Zeng FF#, Xu CH#, Liu YT, Fan YY, Lin XL, Lu YK, Zhang CX, Chen YM*. Choline and betaine intakes are associated with reduced risk of nasopharyngeal carcinoma in adults: a case-control study. Br J Cancer 2014 Feb 4;110(3):808-16.
42.Zhang ZQ, Ho SC*, Chen ZQ, Zhang CX, Chen YM*. ?Reference values of bone mineral density and prevalence of osteoporosis in Chinese adults. Osteoporos Int 2014 Feb;25(2):497-507.
43.Zeng FF, Fan F, Xue WQ, Xie HL, Wu BH, Tu SL, Ouyang WF, Chen YM*. The association of red meat, poultry, and egg consumption with risk of hip fractures in elderly Chinese: a case-control study. Bone 2013 October; 56(2):242–248.?
44.Xie HL, Wu BH, Xue WQ, He MG, Fan F, Ouyang WF, Tu SL, Zhu HL, Chen YM*.? Greater intake of fruit and vegetables is associated with lower risk of osteoporosis-related hip fractures in elderly Chinese: a 1:1 matched case-control study. Osteoporos Int 2013 Nov;24(11):2827-36.
45.Zeng FF, Wu BH, Fan F, Xie HL, Xue WQ, Zhu HL, Chen YM*.Dietary patterns and the risk of hip fractures in elderly Chinese: A matched case-control study. J Clin Endocrinol Metab 2013 Jun;98(6):2347-55.
46.He LP, Tang XY, Ling WH, Chen WQ, Chen YM*. Early C-reactive protein in the prediction of long-term outcomes after acute coronary syndromes: a meta-analysis of longitudinal studies. Heart. 2010;96:339-346.
47.Chen YM, Ho SC*, Lam SS. Higher sea fish intake is associated greater bone mass and lower osteoporosis risk in postmenopausal Chinese women. Osteoporos Int. 2010 Jun;21(6):939-46.
48.Wu JN, Ho SC, Zhou C, Ling WH, Chen WQ, Wang CL, Chen YM*. Coffee consumption and risk of coronary heart diseases: A meta-analysis of 21 prospective cohort studies. Int J Cardiol. 2009; 137: 216-225.
49.Chen YM, Teucher B, Tang XY, Dainty JR, Lee KK, Woo JL, Ho SC*. Calcium Absorption in Postmenopausal Chinese Women: A Randomized Crossover Intervention Study. Br J Nutr 2007;97(1):160-6.
50.Chen YM, Ho SC*, Lam SS, Chan SS. Validity of body mass index and waist circumference in the classification of obesity as compared to percent body fat in Chinese middle-aged women. Int J Obes 2006;30(6):918-925.
51.Chen YM, Ho SC*, Lam SS, Ho SS, Woo JL. Soy isoflavones have a favorable effect on bone loss in Chinese postmenopausal women with lower bone mass: a double-blind, randomized, controlled trial. J Clin Endocrinol Metab.2003 Oct; 88(10):4740-4747.
参编教材与论著
1.? 陈裕明. 队列研究. 王建华 主编. 流行病学大参考（第一卷）（第三版）.
人民卫生出版社. 2015 .
2.? 陈裕明. 骨质疏松流行病学. 沈红兵 主编. 流行病学大参考（第三卷）（第三
版）.人民卫生出版社。2014.
3.? 陈裕明. 第八章 宏量营养素 第一节 钙。中国营养学会 编著. 中国居民膳食
营养素参考摄入量（2013版）.科学出版社，2014.10
4.? 陈裕明（编委）. 预后研究. 沈洪兵 齐秀英 主编. 流行病学. 人民卫生出版社. 2013: pp:114-124. (教材)
5.? 刘苑婷 陈裕明. 第七节? 蔬菜水果与肿瘤. 石汉平、凌文华、李薇 主编.? 肿瘤营养学. 人民卫生出版社 2012
6.? 刘苑婷 陈裕明. 第十节 全谷类食物与肿瘤. 石汉平、凌文华、李薇 主编. 肿瘤营养学. 人民卫生出版社 2012
7.??Yu-ming Chen?and Suzanne C. Ho. Fruit, Vegetables, and Bone Health. In Ronald Ross Watson and Victor R. Preedy, editors: Bioactive Foods in Promoting Health, Oxford: Academic Press, 2010： pp. 173-194.
研究生与博士后培养、专职科研人员招聘
1.? 硕士研究生 每年2-3名 （方向：营养流行病学）
2. 博士研究生 每年1名?? （方向：流行病学 或 营养学）
3. 博士后???? 名额不限? （方向：流行病学 或 营养学）
4. 特聘研究员或副研究员 1-2名
4. MPH和单考班
获奖情况
1. 2013年? 中国营养学会营养相关植物化学物优秀科技论文 二等奖?
2. 2008年? 中国营养学会第二届营养科技奖 二等奖 （第二名）
3. 2006年? 教育部“新世纪优秀人才”
4. 1998年? 广东省教育厅、广东省高教厅等? 南粤教坛新秀
?