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办公地址：广州市大学城外环东路132号中山大学药学院
简单介绍潘昕，女，中山大学药学院副教授,博导。2011年毕业于中山大学，获药剂学博士学位，后留校任教。
研究方向主要研究领域为药物新型制剂和药物释放系统，近年来承担课题10余项，其中包括2017年国家重大新药创新专项子课题，国家自然科学基金青年基金、863子课题、2014年度珠江科技新星、教育部博士点基金、中国博士后科学基金第51批面上资助、广东省医学科研基金等项目。在国内外重要学术刊物，包括Drug Delivery, Eur J Pharm Sci, Eur J Pharm Biopharm, Int J Nanomed, Curr Pharm Design, Int J Pharm, AAPS Pharmscitech等发表论文50余篇，申请专利36项，其中有关制剂应用基础研究的授权专利7项，3项有偿转化。
? ? ?? 学术兼职包括国际专业杂志如Int J Pharm, Eur J Pharm Biopharm, AAPS Pharmscitech, Drug Development and Industrial Pharmacy, Analytical method等审稿人。广东省药学会药物制剂专业委员会秘书长，美国药学科学家协会（AAPS）、国际微囊协会、国际控释协会（CRS）、中国吸入制剂联盟（IDDA）等专业会员。

教育经历2006.09-2011.06?????博士，药剂学，?中山大学，广州?
2002.09-2006.07?????学士，药学，中山大学，广州
工作经历2015.12至今 ? ? ? ? ? ? ? 中山大学药学院副教授
2013.07-2015.12????????中山大学药学院讲师
2011.07-2013.06????????中山大学药学院师资博士后
社会/学术任职1)????????广东省药学会药物制剂专业委员会秘书长
2)????????第二届工业药学与临床药学研讨会（Symposium on Industrial Pharmacy and Clinical Pharmacy）组委会组长
3)????????国际专业杂志Drug Development and Industrial Pharmacy、Analyze method等特邀评审
4)????????美国药学科学家协会American Association of Pharmaceutical Scientists (AAPS)?会员
5)????????国际控释协会Control Release Society (CRS)?会员
6)????????中国吸入制剂联盟Inhalation Drug Delivery Association (IDDA)?会员
7)????????美国药学科学家协会中山大学学生分会(AAPS Sun Yat-Sen University Student Branch )?发起人
荣誉奖励
1) ? ? ?? 2017年广东省科学技术二等奖
2) ? ? ?? 2016 中国产学研合作创新成果奖二等奖（3/7，长效注射微球技术开发及产业化应用，吴传斌团队）
3) ? ? ?? 2016 年中国药学会青年药剂学奖
4) ? ? ?? 2014 广州市珠江科技新星


科研项目1)????? “长效缓控释微球产业化共性关键技术与创新制剂研发-注射用促红细胞生成素微球；国家重大新药创制专项子课题，264.90万元；项目负责人；项目编号：2017ZX**-017
2)????? “干粉吸入剂二元载体表面微结构的定向构建及其增效机理的研究”；国家自然基金面上项目，51万；项目负责人；2017/01-2020/12
3)????? “药食同源多组分功能因子在临床营养制剂中的稳定性研究、工艺研究及中试、产品质量评价”；国家高技术研究发展计划（863 计划）子课题，项目负责人；90万元；2014/01-2016/12。项目编号：2014AA022204
4)????? “基于超细微粒制备技术的微粒成丸机理研究及其在微丸片中的应用”；国家自然科学基金青年基金；23万元；项目负责人；2013/01-2015/12。项目编号：**
5)????? “超细微粒制造系统制备骨架微丸的机理研究及其在口崩微丸片产业化中的应用”，广州市珠江科技新星；30万元；项目负责人；2014/04-2017/03。项目编号：
6)????? “智能型低温超微粒药物制备系统的设计及理论研究”；广东省自然科学基金团队项目；核心成员，等同于项目负责人；50万元, 2016/01-2018/12。
7)????? “基于超细微粒制备技术的微粒成球机理研究及其在石杉碱甲口崩型缓释微丸片中的应用”；教育部博士点基金新教师类；4万元；项目负责人；2012-2014年。项目编号：046
8)????? “基于超细微粒制备技术的微粒成丸机理及其在口崩型缓释微丸片的中的应用”；中国博士后科学基金委；5万元；项目负责人；2011-2013年。项目编号：2012M511625
9)????? “石杉碱甲口崩型缓释微丸片的研究”；广东省卫生厅医学科研基金；0.5万元；项目负责人；2012-2013年。项目编号：B**
10) ?? “多孔/微粗糙甘露醇载体的形成机制及其在干粉吸入剂中的应用”；高校基本科研业务费中山大学青年教师培育项目；15万元；项目负责人。

论著专利部分代表性论文（近三年）：1)????? Y. Huang#, Z. Huang#, X.?Zhang, Z.?Zhao, X.?Zhang, K.?Wang,?C.?Ma,?C.?Zhu, X.?Pan*, C.?Wu. Chitosan-based binary dry powder inhaler carrier with nanometer roughness for improving in vitro and in vivo aerosolization performance. Drug Delivery and Translational Research, 2018, 2018, 8(5): 1274.
2)????? X. Li, Y. Huang, Z. Huang, X. Ma, N. Dong, W. Chen, X. Pan* and C. Wu. Enhancing stability of exenatide containing pressurized metered-dose inhaler via reverse microemulsion system. AAPS Pharm Sci Tech. 2018, 19(6): 2499-2508.?
3)????? T. Peng, P. Yang, C. Zhu*, X. Zhang, X. Wang, H. Ran, X. Bai, J. Zhang, C. Wu, X. Pan*, C. Wu, Mechanistic investigation on the performance of Huperzine a loaded microparticles based on ultra-fine particle processing system, Powder Technology, 2018, 326: 370-378.??
4)????? S. Lin, B. Cai, G. Quan, T. Peng, G. Yao, C. Zhu, Q. Wu, H. Ran, X. Pan*, C. Wu*. Novel strategy for immunomodulation: Dissolving microneedle array encapsulating thymopentin fabricated by modified two-step molding technology, European Journal of Pharmaceutics and Biopharmaceutics, 2018, 122: 104-112.
5)????? L. Chen, L. Mei, D. Feng, D. Huang, X. Tong, X. Pan, C. Zhu*, C. Wu, Anhydrous reverse micelle lecithin nanoparticles/PLGA composite microspheres for long-term protein delivery with reduced initial burst. Colloids and Surfaces B: Biointerfaces, 2018, 163: 146-154.
6)????? L. Mei, Y. Xie, X. Huang, J. Chen, Y. Huang, B. Wang, H. Wang, X. Pan*, C. Wu. An injectable in situ gel with cubic and hexagonal nanostructures for local treatment of chronic periodontitis. Drug Delivery, 2017, 24(1): 1148-1158.?
7)????? L. Mei, J. Chen, S. Yu, Y. Huang, Y. Xie, H. Wang, X. Pan*, C Wu. Expansible thermal gelling foam aerosol for vaginal drug delivery. Drug Delivery, 2017, 24(1): 1325-1337.
8)????? Z. Huang, H. Wu, B. Yang, L. Chen, Y. Huang, G. Quan, C. Zhu, X. Li, X. Pan*, C. Wu. Anhydrous reverse micelle nanoparticles: new strategy to overcome sedimentation instability of peptide-containing pressurized metered dose inhalers. Drug Delivery, 2017, 24(1): 527-538.
9)????? L. Mei, Y. Xie, Y. Huang, B. Wang, J. Chen, G. Quan, X. Pan*, H. Liu, L. Wang, X. Liu, C. Wu. Injectable in situ forming gel based on lyotropic liquid crystal for persistent postoperative analgesia. Acta Biomaterialia, 2018, 67: 99-110. ?
10)??? X. Zhang, J. Zhang, G. Quan, P. Yang, X. Pan*, C. Wu. The serum-resistant transfection evaluation and long-term stability of gene delivery dry powder based on mesoporous silica nanoparticles and polyethyleneimine by freezing-drying. AAPS PharmSciTech. 2017, 18(5): 1536–1543.
11)??? J. Zhang, X. Zhang, X. Wang, Y. Huang, B. Yang, X. Pan*, C. Wu. The influence of maltodextrin on the physicochemical properties and stabilization of beta-carotene emulsions, AAPS PharmSciTech. 2017, 18(3): 821-828.?
12)??? X. Shi, T. Peng, Y. Huang, L. Mei, Y. Gu, J. Huang, K. Han, G. Li, C. Hu, X. Pan*, C. Wu. Comparative studies on glycerol monooleate- and phytantriol-based cubosomes containing?oridonin in vitro and in vivo. Pharm Dev Technol. 2017, 22(3): 322-329.
13)??? Y. Zhou, F. Li, B. Wang, J. Chen, Y. Huang, X. Pan*, G. Li, H. Chen, M. Feng, C. Wu, Stability of the new type of L.Bulgaricus microcapsule, Acta Pharmaceutica Sinica, 2017, 52(7): 1165-1169.
14)??? G. Quan, B. Niu, V. Singh, Y. Zhou, C-Y Wu, X. Pan*, C. Wu*. Supersaturable solid self-microemulsifying drug delivery system: precipitation inhibition and bioavailability enhancement. Int J Nanomed. 2017, 12: 8801-8811.
15)??? T. Peng^#, X. Zhang^#, Y. Huang, Z. Zhao, Q. Liao, J. Xu, Z. Huang, J. Zhang, C. Wu, X. Pan*, C. Wu*. Nanoporous mannitol carrier prepared by non-organic solvent spray drying technique to enhance the aerosolization performance for dry powder inhalation. Scientific Reports, 2017, 7: 46517.
16)??? G. Yao, G. Quan, S. Lin, T. Peng, Q. Wang, H. Ran, H. Chena, Q. Zhang, L. Wang, X. Pan*, C. Wu*. Novel dissolving microneedles for enhanced transdermal delivery of levonorgestrel: in vitro and in vivo characterization. Int J Pharm. 2017, 534: 378-386.
17)??? Z. Huang, X Chen, F. Han, X. Wen, C. Ma, J. Zhang, C. Wu, Y. Huang*, X. Pan*, C. Wu. Formation mechanism and in vitro evaluation of risperidone-containing plga microspheres fabricated by ultrafine particle processing system. Journal of Pharmaceutical Science, 2017, 106(11): 3363-3371.
18)??? J. Huang, T. Peng, Y. Li, Z. Zhan, Y. Zeng, Y. Huang*, X. Pan*, C. Wu. Ocular cubosome drug delivery system for timolol maleate: preparation, characterization, cytotoxicity, ex vivo and in vivo evaluation. AAPS PharmSciTech. 2017, 18(8): 2919-2926.
19)??? H. Zhou, S. Li, Y. Chen, Q. Zhang, X. Bai, C. Zhu*, H. Liu, L. Wang, C-Y Wu, X. Pan*, C. Wu, Evaluation of Streptococcus Thermophilus IFFI 6038 microcapsules prepared using an ultra-fine particle processing system, AAPS PharmSciTech. 2017, 19(3): 1020-1028.
20)??? W. Pan, J. Ma, X. Xiao, Z. Huang, H. Zhou, F. Ge*, X. Pan*, Near-infrared spectroscopy assay of key quality-indicative ingredients of tongkang tablets, AAPS PharmSciTech. 2017, 18(3): 913-919.
21)??? H. Zhou, J. Chen, S. Li, J. Zhang, C. Zhu, H. Ran, M. Luo, X. Pan*, H. Hu*, C. Wu. Preparation of acid-resistant microcapsules with shell-matrix structure to enhance stability of Streptococcus Thermophilus IFFI 6038. Journal of Food Science, 2017, 82(8): 1978-1984. ?
22)??? Z. Zhan, X Zhang, J. Huang, Y. Huang, Z. Huang, X. Pan, G. Quan*, H. Liu, L. Wang, C. Wu. Improved gene transfer with functionalized hollow mesoporous silica nanoparticles of reduced cytotoxicity. Materials, 2017, 10(7): 731.
23)??? J Zhang, C-Y Wu*, X Pan, C Wu. On identification of critical material attributes for compression behaviour of pharmaceutical diluent powders. Materials, 2017, 10(7): 845.
24)??? L. Mei, Y. Xie, H. Jing, Y. Huang*, J. Chen, H. Ran, X Pan, C. Wu. A novel design for stable self-assembly cubosome precursor-microparticles enhancing dissolution of insoluble drugs. Drug development and Industrial Pharmacy, 2017, 43(8): 1239-1243.
25)??? C. Ma, Z. Huang, Y. Zhu, X. Chen, Vikramjeet Singh, Y. Huang*, X. Pan, C. Wu. Production and in vitro evaluation of lamotrigine extend release tablet based on controlled-porosity osmotic pump system. Pharmazie. 2017, 72: 511-51.
26)??? G. Quan, Q. Wu, X. Zhang, Z. Zhan, C. Zhou, B. Chen, Z. Zhang, G. Li, X. Pan*, C. Wu*. Enhancing in vitro dissolution and in vivo bioavailability of fenofibrate by solid self-emulsifying matrix combined with SBA-15 mesoporous silica. Colloids and Surfaces B: Biointerfaces, 2016, 141: 476-482.
27)??? J. Zhang, X. Zhang, X. Wang, Y. Huang, B. Yang, X. Pan*, C. Wu. The influence of maltodextrin on the physicochemical properties and stabilization of beta-carotene emulsions. AAPS PharmSciTech. 2016, 18(3): 821-828.
28)??? T. Peng, S. Lin, B. Niu, X. Wang, Y. Huang, X. Zhang, G. Li, X. Pan*, C. Wu*, Influence of physical properties of carrier on the performance of dry powder inhalers Acta Pharmaceutica Sinica B, 2016 ,6(4): 308-318
29)??? L. Qin, L. Mei, Z. Shan, X. Pan*, C. Wu. Phytantriol based liquid crystal provide sustained release of anticancer drug as a novel embolic agent. Drug Development and Industrial Pharmacy, 2016, 42(2): 307-316.
30)??? L. Huang, J. Yu, X. Pan, T. Peng, Y. Cheng*, Modelling the triphasic mechanics of porous material in articular cartilage, Emerging Materials Research, 2016, 5(1): 50-56.
31)??? J. Ji, J. Zhang, J. Chen, Y. Wang, X. Wang, N. Dong, C. Hu, H. Chen, G. Li, X. Pan*, C. Wu. Preparation and stabilization mechanism of emulsions stabilized by mixed sodium caseinate and soy protein isolate. Food Hydrocolloids, 2015, 51: 156-165.
32)??? C. Zhu, Y. Huang, X. Zhang, L. Mei,G Li, X. Pan*, C. Wu. Comparative studies on exenatide-loaded poly (d, l-lactic-co-glycolic acid) microparticles prepared by a novel ultra-fine particle processing system and spray drying. Colloids and Surfaces B: Biointerfaces, 2015, 132: 103-110.?
33)??? T. Peng, C. Zhu. Y. Huang, G. Quan, L. Huang, L. Wu, X. Pan*, G. Li, C. Wu. Improvement of the stability of doxycycline hydrochloride pellet-containing tablets through a novel granulation technique and proper excipients. Powder Technology, 2015, 270: 221-229.
34)??? Y. Huang, C Zhu, G Li, X. Pan*, C. Wu. Metoprolol tartrate sustained-release binary matrix microspheres for oral administration produced by novel ultra-fine particle processing system. Powder Technology, 2015, 285: 44-50.
35)??? X. Peng, Y. Zhou, K. Han, L. Qin, L. Dian, G. Li, X. Pan*, C. Wu*. Characterization of cubosomes as a targeted and sustained transdermal delivery system for capsaicin. Drug Design Development and Therapy, 2015, 9: 4209-4218.
36)??? Y. Huang, Q. Yao, C. Zhu, X. Zhang, L. Qin, Q. Wang, X. Pan*, C. Wu. Comparison of novel granulated pellet-containing tablets and traditional pellet-containing tablets by artificial neural networks. Pharmaceutical Development and Technology, 2015, 20: 670-675.
37)??? T. Peng, Y. Huang, L. Mei, L. Wu, L. Chen, X. Pan*, C. Wu. Study progression in application of process analytical technologies on film coating. Asian Journal of Pharmaceutical Sciences, 2015, 10(3): 176-185
38)??? G. Quan, X. Pan, Z. Wang, Q. Wu, G. Li, L. Dian, B. Chen, C. Wu*.Lactosaminated mesoporous silica nanoparticles for asialoglycoprotein receptor targeted anticancer drug delivery. Journal of Nanobiotechnology, 2015, 13: 7-18.
39)??? Z. Zhang, G. Quan, Q. Wu, Chan Zhou, F. Li, X. Bai, G. Li, X. Pan, C. Wu*. Loading amorphous asarone in mesoporous silica sba-15 through supercritical carbon dioxide technology to enhance dissolution and bioavailability. European Journal of Pharmaceutics and Biopharmaceutics, 2015, 92: 28-31.
40)??? Y. Dong, P. Dong, D. Huang, L. Mei, Y. Xia, Z. Wang, X. Pan, G. Li, C. Wu*. Fabrication and characterization of silk fibroin-coated liposomes for ocular drug delivery. European Journal of Pharmaceutics and Biopharmaceutics, 2015, 91: 82-90.
41)??? J. Zhang, M. Zhang, J. Ji, X. Fang, X. Pan, Y. Wang*, C. Wu, M. Chen*, Glycyrrhetinic acid-mediated polymeric drug delivery targeting the acidic microenvironment of hepatocellular carcinoma, Pharmaceutical Research, 2015, 32(10): 3376-3390.
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授权专利及专利：
1)????????潘昕，吴传斌。一种微丸片的制备方法中国专利号：ZL 8.6
2)????????吴传斌，吴涵，潘昕。水溶性药物无水反胶束纳米粒及其混悬型气雾剂的制备方法，中国专利号：1.3
3)????????潘昕，黄莹，彭婷婷，张雪娟。表面纳米级粗糙结构的颗粒及其制备方法和应用，中国专利申请号：2.6
4)????????潘昕，黄莹，梅丽玲。一种缓释立方液晶液体硬胶囊的制备和应用，中国专利申请号：5.X：
5)????????潘昕，陈龙楷，冯地桑，黄莹，吴涵，吴传斌。磷脂蛋白质微粒复合微球及其制备方法。中国专利申请号：0.4
6)????????吴传斌，潘昕，付寒。利培酮微球及其制备方法，中国专利申请号：2.5
7)????????吴传斌，潘昕，杜鹏阳，李姝瑾。细辛脑干粉吸入剂及其制备方法，中国专利申请号：9.0
8)????????吴传斌，潘昕，周玥鋆，温新国。美托洛尔缓释微球、缓释药用组合物及其制备方法，中国专利申请号：7.9
9)????????吴传斌，王雯，潘昕。硫酸奈替米星吸入粉雾剂及其制备方法，中国专利申请号：.7
10) ? ?? 吴传斌，袁婷，潘昕。骨化三醇固体脂质分散体及其制备方法，中国专利申请号：.5
学术交流大会报告：
1) ? ? ?? Study on Delivering Macromolecule Drugs，The 1st Diwus Forum on Pharmaceutical Technology, Guangzhou, China, 10 April, 2017.
2) ? ? ?? Influence of Polymers on the Dual Recrystallizations and Physicochemical Stability of Spray-dried Amorphous Solid Dispersion. 2016年中国药学大会， 中国北京。
3) ? ? ?? 溶致液晶凝胶系统的研究及应用，2016中国药学大会，大会报告，2016年12月，中国北京。
4) ? ? ?? The Design and Stabilized Peptide Drugs Used in Pressurized Metered Dose Inhalers(pMDI)，2016中国药学大会，大会报告，2016年11月，中国南京。
5) ? ? ?? 干粉吸入剂纳米粗糙载体的构建及其提高药物传递效率的机理研究，中国颗粒学会学术年会暨海峡两岸颗粒技术研讨会，大会报告，2016年8月，中国成都。
6) ? ? ?? Dry Powder Inhaler Carrier with Nano-metered Topography Roughness Surface and its Enhancement of Lung Delivery Efficiency, Asian Graduate Congress ? on Pharmaceutical Technology, July 9-13, 2016, Singapore.
7) ? ? ?? Peptide drug formulation design based on pMDIs, 2015 SYSU-RMIT Joint Symposium, Nov 17-18，2015, Guangzhou China.
8) ? ? ?? 蛋白质多肽气雾给药系统的设计与评价，第二届全国生物颗粒研讨会，大会报告，2015年12月，中国广州。
9) ? ? ?? Spray-dried Mannitol-Chitosan as Blend Carrier for Dry Powder Inhalers， Particulate Processes in the Pharmaceutical Industry IV, Sep 11-14, 2014, Potsdam, Germany.
10) ? ?? Ultra-fine Particle Process System and Its Application for the Drug-containing Microspheres, The 7^th World Congress of Particle Technology, May 11-14, 2014, Beijing, China.
11) ? ?? 临床营养十三五863重大项目立项前期论证会议，大会报告，2013年3月，中国北京。
12) ? ?? 微丸片制剂产业化技术，中国颗粒学会第八届学术年会，分会场报告，2012年9月，中国杭州。
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