陈月琴
性别：女
工作电话：
电子邮件：lsscyq@mail.sysu.edu.cn
职称：教授
导师类型：博士生导师
学历：博士
学科方向：0710生物学-10生物化学与分子生物学
研究方向：非编码RNA生物学
个人经历：
教育经历：
1984年???? 西北大学生物系????理学学士；
1987年???? 北京大学生物系??? 理学硕士；
1996年???? 中山大学生科院???? 理学博士。
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工作经历：
2003年至今，聘为中山大学教授；
1999年，被聘为中山大学副教授；
1998-2005年先后在法国国家科研中心（CNRS），哈佛大学，美国陆军研究所任客座研究员。
1996-1998年，中山大学博士后。
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讲授课程
《RNA分子生物学》
学术成就
????????? 多年来，一直致力于非编码RNA在水稻和白血病等民生问题的研究。在这个领域中，解析了一大批与生物能源与生物医药息息相关的ncRNA，取得了一系列重大成果，得到国际同行的普遍认可。其中，2013年，在水稻种鉴定的miR-397具有促进水稻产量的研究，得到国际全行业的强烈震撼。目前，陈老师所著成果先后发表在Nature Biotechnology, Genome Biology, Autophagy，PNAS，Science Signaling，Plant Physiology，JBC等国际一流刊物上，共计70余篇。
??????? 所获荣誉：国家自然科学二等奖 、广东省自然科学一等奖 及“丁颖”科技奖 。
承担课题
??????? 先后承担和主持省部级及国家级重大项目10余项。
论文专著
近五年发表代表性论文：
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Huang W, Wang WT, Fang K, Chen ZH, Sun YM, Han C, Sun LY, Luo XQ, Chen YQ*. MIR-708 promotes phagocytosis to eradicate T-ALL cells by targeting CD47. Mol Cancer. 2018 , 17:12.
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Sun LY, Li XJ, Sun YM, Huang W, Fang K, Han C, Chen ZH, Luo XQ, Chen YQ*, Wang WT*. LncRNA ANRIL regulates AML development through modulating the glucose metabolism pathway of AdipoR1/AMPK/SIRT1. Mol Cancer. 2018,17:127.
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Chen ZH, Wang WT, Huang W, Fang K, Sun YM , Liu SR,Luo XQ, Chen YQ*. The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway. Cell Death Differ. 2017,24: 212-24.
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Zhang JP, Yu Y, Feng YZ, Zhou YF, Zhang F, Yang YW, Lei MQ, Zhang YC, Chen YQ*. MiR408 Regulates Grain Yield and Photosynthesis via a Phytocyanin Protein. Plant Physiol. 2017 ,175:1175-85.
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Lin KY, Ye H, Han BW, Wang WT, Wei PP, He B Li XJ, Chen YQ*. Genome-wide screen identified let-7c/miR-99a/miR-125b regulating tumor progression and stem-like properties in cholangiocarcinoma. Oncogene. 2016,35: 3376-86.
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Wang WT, Ye H, Wei PP, Han BW, He B, Chen ZH, Chen YQ*. LncRNAs H19 and HULC, activated by oxidative stress, promote cell migration and invasion in cholangiocarcinoma through a ceRNA manner. J Hematol Oncol. 2016, 9:117.
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Zhang YC, Liao JY, Li ZY, Yu Y, Zhang JP, Li QF, Qu LH, Shu WS, Chen YQ*. Genome-wide screening and functional analysis identify a large number of long noncoding RNAs involved in the sexual reproduction of rice. Genome Biology. 2014,15:512.
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Zeng CW, Chen ZH, Zhang XJ, Han BW, Lin KY, Li XJ, Wei PP, Zhang H, Li YQ, Chen YQ*. MIR125B1 represses the degradation of the PML-RARA oncoprotein by an autophagy lysosomal pathway in acute promyelocytic leukemia. Autophagy. 2014,10, 1726–37.
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Fang K, Han BW, Chen ZH, Lin KY, Zeng CW, Li XJ,Li JH, Luo XQ, Chen YQ*. A distinct set of long non-coding RNAs in childhood MLL-rearranged acute lymphoblastic leukemia: biology and epigenetic target. Hum Mol Genet. 2014, 23: 3278-88.
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Wang, CY, Zhang SC, Yu Y, Luo YC, Liu Q Ju CL, Zhang YC, Qu LH, Lucas WJ, Wang XJ, Chen YQ*.MiR397b Regulates Both Lignin Content and Seed number in Arabidopsis via Modulating a Laccase Involved in Lignin Biosynthesis. Plant Biotech J. 2014, 12(8):1132-42.
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Wang WT, Zhao YN, Yan JX, Weng MY, Wang Y, Chen YQ*, Hong SJ. Differentially expressed microRNAs in the serum of cervical squamous cell carcinoma patients before and after surgery. J Hematol Oncol. 2014 Jan 10;7:6.
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Wang WT, Chen YQ*. Circulating miRNAs in cancer: from detection to therapy. J Hematol Oncol. 2014 ,5;7:86.
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Zhang YC, Yu Y, Wang CY, Li ZY, Liu Q, Xu J, Liao JY, Wang XJ, Qu LH, Chen F, Xin P, Yan C, Chu J, Li HQ, Chen YQ*.Overexpression of microRNA OsmiR397 improves rice yield by increasing grain size and promoting panicle branching. Nat Biotechnol. 2013, 31：848-53.
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Han BW, Chen YQ*. Potential Pathological and Functional Links Between Long Noncoding RNAs and Hematopoiesis. Sci. Signal. 2013, 6, re5.
Wang WT, Zhao YN, Han BW, Hong SJ, Chen YQ*. Circulating microRNAs identified in a genome-wide serum microRNA expression analysis as noninvasive biomarkers for endometriosis.J Clin Endocrinol Metab. 2013, 98:281-9.
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Duan FT, Qian F, Fang K, Lin KY, Wang WT, Chen YQ*. miR-133b, a muscle-specific microRNA, is a novel prognostic marker that participates in the progression of human colorectal cancer via regulation of CXCR4 expression. Mol Cancer. 2013, 13;12:164.