职位副教授
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赵军岭，药学院（深圳）副教授。目前的主要研究兴趣包括有机小分子催化的不对称合成方法学、生物活性有机小分子的合成等。具体包括吲哚类化合物在不对称合成中的新应用、基于吲哚结构的新型抗HIV药物的合成以及新型抗流感药物的发现。主持的项目包括国家自然科学基金青年基金、面上项目，广州市“珠江科技新星”项目，并于2016年入选了中国科学院“青年创新促进会”。近年来以通讯作者在Angew. Chem. Int. Ed.，ACS Cat.， Org. Lett.，Adv. Synth. Catal.等国际知名期刊发表20多篇高水平学术论文，担任ACS Cat.，Org. Lett.，J. Org. Chem.，Adv. Synth. Catal.等杂志审稿人。
电子邮箱zhaojling3@mail.sysu.edu.cn
个人经历1999.9-2003.6 河北大学化学与环境科学学院，学士
2003.9-2008.7 中国科学院化学研究所，博士（硕博连读），导师：陈拥军研究员
2008.9-2010.8 香港理工大学，研究助理，合作导师：陈新滋院士
2010.9-2011.12 中国科学院广州生物医药与健康研究院，助理研究员
2012.1-2017.4 中国科学院广州生物医药与健康研究院，副研究员
2017.5-2020.5 中山大学药学院，特聘研究员
2020.5-至今 中山大学药学院（深圳），副教授
研究方向不对称合成方法学，有机小分子催化，吲哚化学，手性小分子药物研究
科研项目1.????????? 国家自然科学基金面上项目（**），2020.1-2023.12，在研，主持
2.????????? 国家自然科学基金面上项目（**），2018.1-2021.12，在研，主持
3.????????? 中国科学院青年创新促进会（**），2016.1-2019.12，已结题，主持
4.????????? 国家自然科学基金青年基金（**），2012.1-2014.12，已结题，主持
5.????????? 广州市科创委珠江科技新星项目（2012J**），2012.7-2015.6，已结题，主持
代表论著1.????????? Yunlong Zhao, Lu Cai, Tongkun Huang, Shanshui Meng,* Albert S. C. Chan,* Junling Zhao* Solvent-Mediated C3/C7 Regioselective Switch in Chiral Phosphoric Acid-Catalyzed Enantioselective Friedel-CraftsAlkylation of Indoles with α-Ketiminoesters, Advanced Synthesis & Catalysis 2020, 362, 1309-1316
2.????????? zhuqing Jia, Xiaoyi Hu, Yunlong Zhao, Fayang G. Qiu,* Albert S. C. Chan,* Junling Zhao* One-Pot Enantioselective Synthesis of 2-Pyrrolidinone Derivatives Bearing a Trifluoromethylated All-Carbon Quaternary Stereocenter, Organic Letters 2019, 21, 9584-9588
3.????????? Shanshui Meng,*# Xiaowen Tang,# Xiang Luo, Ruibo Wu, Junling Zhao,* Albert S. C. Chan,* Borane-Catalyzed Chemoselectivity-Controllable N-Alkylation and ortho C-Alkylation of Unprotected Arylamines Using Benzylic Alcohols, ACS Catalysis, 2019, 9, 8397-8403
4.????????? Shanshui Meng,* Lirong Lin, Haojun Lv, Junling Zhao,* Albert S. C. Chan,* Aerobic oxidation of alcohols with air catalyzed by decacarbonyldimanganese, Green Chem. 2019, 21, 6187-6193
5.????????? Lu Cai,# Yunlong Zhao,# Tongkun Huang, Shanshui Meng,* Albert S. C. Chan,* Junling Zhao,* Chiral Phosphoric Acid Catalyzed Regio and Enantioselective C7 Friedel-Crafts Alkylation of 4-Aminoindoles with Trifluoromethyl Ketones, Organic Letters 2019, 21, 3538-3542
6.????????? Tongkun Huang,# Yunlong Zhao,# Shanshui Meng,* Albert S. C. Chan,* Junling Zhao,* C7-Functionalization of Indoles via Organocatalytic Enantio- selective Friedel-Crafts Alkylation of 4-Aminoindoles with 2-Butene-1,4-diones and 3-Aroylacrylates, Advanced Synthesis & Catalysis 2019, 361, 3632-3638
7.????????? Wen Xun, Bo Xu, Bo Chen, Shanshui Meng, Albert S. C. Chan, Fayang G. Qiu,* Junling Zhao* Regio and Enantioselective Organocatalytic Friedel?Crafts Alkylation of 4?Aminoindoles at the C7-Position, Organic Letters 2018, 20, 590-593
8.????????? Mengjie Xiao, Dengfeng Xu, Weihong Liang, Wenyu Wu, Albert S. C. Chan, Junling Zhao* Organocatalytic EnantioselectiveFriedel–Crafts Alkylation/Lactonization Reaction of Hydroxyindoles with Methyleneoxindoles, Advanced Synthesis & Catalysis 2018, 360, 917-924. (Very Important Publication, Front Cover)
9.????????? Yuyang Ding, Dengfeng Xu, Shanshui Meng,* Yang Li,* Junling Zhao* Chiral Phosphoric Acid Catalyzed Enantioselective Friedel-Crafts Reaction of N-Protected 4-Aminoindoles with β,γ-Unsaturated α-Ketimino Esters, Advanced Synthesis & Catalysis 2018, 360, 664-669
10.?????? Zhengtu Li,# Junling Zhao,# Hongxia Zhou, Li Li, Yuyang Ding, Jing Li, Beixian Zhou, Haiming Jiang, Nanshan Zhong, Wenhui Hu, Zifeng Yang* Cappariloside A shows antiviral and better anti-in?ammatory e?ects against in?uenza virus via regulating host IFN signaling, in vitro and vivo, Life Sciences 2018, 200, 115-125.
11.?????? Shanshui Meng,* Qian Wang, Gongbin Huang, Lirong Lin, Junling Zhao,* Albert S.C. Chan,* B(C6F5)3 Catalyzed Direct Nucleophilic Substitution of Benzylic Alcohols: An Effective Method of Constructing C-O, C-S and C-C Bonds from Benzylic Alcohols, RSC Advances, 2018, 8, 30946-30949.
12.?????? Yunlong Zhao, Qinxin Lou, Longsheng Wang, Wenhui Hu,* Junling Zhao* OrganocatalyticFriedel-Crafts Alkylation/Lactonization Reaction of Naphthols with 3-Trifluoroethylidene Oxindoles: The Asymmetric Synthesis of Dihydrocoumarins, Angewandte Chemie International Edition 2017, 56, 338-342
13.?????? Qinxin Lou, Yuyang Ding, Dengfeng Xu, Guokai Liu,* Junling Zhao* Organocatalytic Enantioselective Synthesis of Dihydropyranoindole Derivatives Bearing Trifluoromethylated All-Carbon- Substituted Stereocenters, Advanced Synthesis & Catalysis 2017, 359, 2557-2563
14.?????? Qing Yang, Yuyang Ding, Fengling Feng, Enxiang Pan, Xiaozhen Fan, Xiuchang Ma, Ling Chen, Junling Zhao,* Caijun Sun* Structure-optimized dihydropyranoindole derivative GIBH-LRA002 potentially reactivated viral latency in primary CD4+ T lymphocytes of chronic HIV-1 patients, MedChemComm 2017, 8, 1806-1809. (Hot article)
15.?????? Yunlong Zhao, Longsheng Wang,* Junling Zhao* Chiral Phosphoric Acid Catalyzed Aza-Friedel-Crafts Alkylation of Indoles with Cyclic Aryl α-Ketimino Esters, Tetrahedron Letters 2017, 58, 213-217
16.?????? Bo Bi, Qinxin Lou, Yuyang Ding, Shengwei Chen, Shasha Zhang, Wenhui Hu,* Junling Zhao* Chiral Phosphoric Acid Catalyzed Highly EnantioselectiveFriedel?Crafts Alkylation Reaction of C3-Substituted Indoles to β,γ-Unsaturated α?Ketimino Esters, Organic Letters 2015, 17, 540-543
17.?????? Shengwei Chen, Qinxin Lou, Yuyang Ding, Shasha Zhang, Wenhui Hu,* Junling Zhao* Organocatalytic Enantioselective Michael Reaction of Malononitrile with β,β-Disubstituted Nitroalkenes, Advanced Synthesis & Catalysis 2015, 357, 2437-2441. (Very Important Publication, Front Cover)
18.?????? Shengwei Chen, Guicheng Zhang, Qinxin Lou, Wei Cui, Shasha Zhang, Wenhui Hu,* Junling Zhao* Organocatalytic Enantioselective Aza-Michael Reaction of Benzotriazole to β, β-Disubstituted Nitroalkenes, ChemCatChem 2015, 7, 1935-1938.(Cover Story)
19.?????? Yuyang Ding, Liufeng Mao, Dengfeng Xu, Hui Xie, Ling Yang, Hongjiang Xu, Wenjun Gen, Yong Gao, Chunguang Xia, Xiquan Zhang, Qingyi Meng, Donghai Wu, Junling Zhao,* Wenhui Hu* C-Aryl Glucoside SGLT2 Inhibitors Containing a Biphenyl Motif as Potential Anti-diabetic Agents, Bioorganic Medicinal Chemistry Letters 2015, 25, 2744-2748
专利申请
孙彩军，赵军岭，陈凌，阳晴，丁宇洋，一种吡喃并吲哚类化合物及其制备方法和在制备抗艾滋病的药物中的应用，4
赵军岭，胡文辉，徐登峰，丁宇洋，杨玲，徐宏江，C-三芳基葡萄糖苷类SGLT-2抑制剂，8
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