基本介绍
张萍副教授
抗病毒免疫无
女硕士导师
免疫学020-87331938
无
zhangp36atmail.sysu.edu.cn
个人简介：
2002年获微生物学博士学位；2002－2004年，于美国弗吉尼亚州立大学（VCU）接受博士后培训；2005－2008年，在美国加利福尼亚大学（UCSB）任研究助理。
2009年作为“百人计划”引进人才，受聘于中山大学中山医学院。目前主要研究方向是干扰素抗病毒的分子机制，特别是双链RNA调控的蛋白激酶（PKR），包括它在宿主抗病毒效应和病毒感染引起的细胞凋亡，以及抗病毒感染的天然免疫信号传导通路的调控功能与机制研究。
学术论著与教材：
1.ZhaoduanLiang,SiyuWu,YuyeLi,LiHe,MinhaoWu,LifangJiang,LianqiangFeng,PingZhang(共同通讯作者),XiHuang(共同通讯作者).ActivationofToll-LikeReceptor3ImpairstheDengueVirusSerotype2ReplicationthroughInductionofIFN-binCulturedHepatomaCells.PLoSOne.2011;6(8):e23346.
2.MinhaoWu,AnpingPeng,MingxiaSun,QiuchanDeng,LindaD.Hazlett,JinYuan,XialinLiu,QianyingGao,LianqiangFeng,JunfangHe,PingZhang(共同通讯作者),XiHuang(共同通讯作者).TREM-1AmplifiesCornealInflammationafterPseudomonasaeruginosaInfectionbyModulatingToll-LikeReceptorSignalingandTh1/Th2-TypeImmuneResponses.InfectImmun.2011Jul;79(7):2709-16
3.李玉叶,梁兆端,吴思宇,谢炯,何军芳,吴敏昊,黄曦,张萍(通讯作者).固有免疫调控蛋白PKR串联亲和系统的建立及应用.中华微生物和免疫学杂志.2011,31(6):487-491
4.MinhaoWu,PingZhang,XiHuang.2010.Toll-likereceptorsininnateimmunityandinfectiousdiseases.FrontMedChina.4(4):385-393
5.ChristopherS.McAllister1,AnnM.Toth1,PingZhang,PatriciaDevaux,RobertoCattaneo,andCharlesE.Samuel.2010.MechanismsofProteinKinasePKR-MediatedAmplificationofBetaInterferonInductionbyCProtein-DeficientMeaslesVirus.JournalofVirology,84(1):380-386.
6.PingZhang,JeffreyO.Langland,BertramL.Jacobs,andCharlesE.Samuel.2009.ProteinKinasePKR-DependentActivationofMitogen-ActivatedProteinKinasesOccursthroughMitochondrialAdapterIPS-1andIsAntagonizedbyVacciniaVirusE3L.JournalofVirology,83:5718-5725
7.PingZhang,CharlesE.Samuel.2008.InductionofproteinkinasePKR-dependentactivationofinterferonregulatoryfactor3byvacciniavirusoccursthroughadapterIPS-1signaling.TheJournalofBiologicalChemistry,283:34580-34587.
8.PingZhang,BertramL.Jacobs，CharlesE.Samuel.2008.LossofproteinkinasePKRexpressioninhumancellscomplementsthevacciniavirusE3Ldeletionmutantphenotypebyrestorationofviralproteinsynthesis.JournalofVirology,82:840-848.
9.PingZhang,CharlesE.Samuel.2007.ProteinKinasePKRPlaysaStimulus-andVirus-dependentRoleinApoptoticDeathandVirusMultiplicationinHumanCells.JournalofVirology,81:8192-200.
10.AnnieM.Toth,PingZhang,SonaliDas,CyrilX.George,CharlesE.Samuel.2006.Interferonactionandthedouble-strandedRNA-dependentenzymesADAR1adenosindeaminasineandPKRproteinkinase.ProgressinNucleicAcidResearchandMolecularBiology,81:369-434.
11.PingZhang,PriyadarshiBasua,LatashaC.Redmonda,PamelaE.Morris,JeremyW.Ruponc,GordonD.Ginder,JoyceA.Lloyd.2005.AfunctionalscreenforKruppel-likefactorsthatregulatethehumangamma-globingenethroughtheCACCCpromoterelement.BloodCells,Molecule,andDiseases.35:227-235.
12.ChongYin,JianxiuYu,LihuaWang,ZhaofeiLi,PingZhang,YiPang.2003.Identificationofanovelproteinassociatedwithenvelopeofocclusion-derivedvirusinSpodopteralituramulticapsidnucleopolyhedrovirus.VirusGenes,26:5-13.
13.PingZhang,KaiYang,XiaojiangDai,YiPang,DemingSu.2002.Infectionofwild-typeAutographacalifornicamulticapsidnucleopolyhedrovirusinducesinvivoapoptosisofSpodopteralituralarvae.JournalofGeneralVirology,83:3003-3311.学术兼职：
AmericanSocietyforVirology会员科研项目研究课题：
- 张萍
- 张萍58.0000万元2011
- 黄曦
- 黄曦张萍20.0000万元2010
- 张萍
- 张萍35.0000万元2009
- 张萍
- 张萍5.0000万元2009
- 张萍
- 张萍23.0000万元2009
