基本情况
巢晖(CHAOHui),男,1970年3月出生,籍贯湖南汨罗,理学博士,教授,博士生导师,现任化学与化学工程学院副院长。
先后在《J.Biol.Inorg.Chem.》、《Inorg.Chem.》、《DaltonTrans》、《J.Inorg.Biochem.》、《Inorg.Chem.Commun》、《Helv.Chim.Acta》等国内外核心期刊发表论文92篇,SCI收录76篇,论文被引用600多篇次。参编英文著作“MetallotherapeuticDrugsandMetal-BasedDiagnosticAgents:TheUseofMetalsinMedicine”(德国JohnWiley&Son出版公司出版,2005年)。被20多种国内外学术刊物(包括Inorg.Chem,J.Phys.Chem.A,J.Phys.Chem.B,DaltonTrans,J.Inorg.Biochem,Inorg.Chem.Commun,Inorg.Chim.Acta,Anal.Chim.Acta,Bioorg.Med.Chem.等)聘请担任论文评审专家。
联系方式
·邮箱:ceschh@mail.sysu.edu.cn
·联系电话:020-84134058(O),84034750(H)
·实验室地址:中山大学南校区化学南楼010/012室
·通讯地址:广州市新港西路135号中山大学化学与化学工程学院丰盛堂
·邮编:510275
教育经历
·1988-1992学士:湖南科技大学化学化工学院;
·1994-1997硕士:南开大学化学学院;
·1997-2000博士:中山大学化学与化学工程学院;
·2000-2003访问学者:香港科技大学化学系;
·2004-2005博士后:美国TexasA&M大学化学系;
工作经历
·2000-2002讲师:中山大学化学与化学工程学院;
·2002-2007副教授:中山大学化学与化学工程学院;
·2008-至今教授:中山大学化学与化学工程学院;
·2002年6月:被遴选为中山大学无机化学专业、化学生物学专业硕士生导师;
·2006年11月:被遴选为中山大学无机化学专业博士生导师;
·2005年-至今:中山大学光电材料与技术国家重点实验室固定研究人员;
·2005年-至今:中山大学生物无机与合成化学教育部重点实验室固定研究人员。
讲授课程
1.本科生:《无机化学》、《无机化学实验》、《现代化学》(逸仙班)
2.研究生:《配位化学》
科研方向
1.DNA/RNA生物大分子结构识别及其生物功能调控的化学基础和应用研究。
2.金属多吡啶配合物为基元的分子器件设计及其光电性能应用。
科研项目
主持和参加国家自然科学基金、973计划项目、教育部新世纪优秀人才支持计划项目、教育部科学技术研究重点项目、教育部留学回国人员科研启动基金、广东省自然科学基金、国家重点实验室开放基金及广东省科技计划项目等多项课题研究。
获奖情况
1.2001年获中国高校自然科学奖二等奖(第九完成人)
2.2005年获中国化学会“青年化学奖”
3.2006年入选教育部”新世纪优秀人才支持计划”
4.2006年入选广东省高等学校“千百十工程”人才培养计划(校级)
5.2007年获中山大学化学与化工学院“53奖教金”
论著一览
1.FengGao,HuiChao*,FengZhou,XinChen,Yuan-FangWei,Kang-ChengZheng,Liang-NianJi*,“Synthesis,DNAbindingandtopoisomeraseIIinhibitionactivitiesofruthenium(II)polypyridylcomplexcontaining11-aminopteridino[6,7-f][1,10]phenanthrolin-13(12H)-one”,J.Inorg.Biochem.,2008,inpress.
2.FengGao,HuiChao*,Liang-NianJi*,“DNA-Binding,PhotocleavgeandTopoisomeraseInhibitingofFunctionalizedRuthenium(II)PolypyridylComplexes”,Chemistry&Biodiversity,2008,inpress.(Review)
3.Hui-JuanYu,HuiChao*,LongJiang,Lv-YingLi,Shu-MeiHuangandLiang-NianJi*,“Singleoxygen-mediatedDNAphotocleavageofadi-bithiazolylruthenium(II)complex[Ru(btz)2(dppz)]2+”,Inorg.Chem.Commun.,2008,inpress.
4.FengGao,HuiChao*,Yuan-FangWei,Yi-XianYuan,BinPeng,XinChen,Kang-ChengZhengandLiang-NianJi*,“Synthesis,DNA-BindingandPhotocleavageStudiesofRuthenium(II)Complexes[Ru(phen)2(ppd)]2+and[Ru(phen)(ppd)2]2+(ppd=Pteridino[6,7-f][1,10]-phenanthroline-1,13(10H,12H)-dione,phen=1,10-Phenanthroline)”,Helv.Chim.Acta,2008,inpress.
5.F.AlbertCotton,HuiChao*,ZhongLi,CarlosA.Murillo,QingshengWang,“Effectofaxialanthraceneligandsontheluminescenceoftrinickelmolecularwires”,J.Organomet.Chem.,2008,inpress.
6.巢晖*,高峰,计亮年*,“钌(II)多吡啶配合物与DNA相互作用研究”,化学进展,2007,19(12),1844-1851。(化学生物学专辑,Review)
7.FengGao,HuiChao*,Jin-QuanWang,Yi-XianYuan,BinSun,Yuan-FangWei,BinPengandLiang-NianJi*,“TargetingtopoisomeraseIIwiththechiralDNA-intercalatingruthenium(II)polypyridylcomplexes”,J.Biol.Inorg.Chem.,2007,12,1015-1027.
8.BinPeng,HuiChao*,BinSun,HongLi,FengGaoandLiang-NianJi*,“Syntheses,DNA-bindingandphotocleavagestudiesofcobalt(III)mixed-polypyridylcomplexes:[Co(phen)2(dpta)]3+and[Co(phen)2(amtp)]3+”,J.Inorg.Biochem.,2007,101,404-411.
9.FengGao,HuiChao*,FengZhou,BinPeng,Liang-NianJi*,“pHresponsive“off-on-off”luminescentswitchofanovelruthenium(II)complex[Ru(bpy)2(pipipH2)]2+”,Inorg.Chem.Commun.,2007,10,170-173.
10.FengGao,HuiChao*,FengZhou,Lian-CaiXu,Kang-ChengZheng,Liang-NianJi*,“Synthesis,Characterization,andDNA-BindingPropertiesoftheChiralRuthenium(II)ComplexesΔ-andΛ-[Ru(bpy)2(dmppd)]2+(dmppd=10,12-Dimethylpteridino-[6,7-f][1,10]phenanthroline-11,13(10H,12H)-dione;bpy=2,2’-Bipyridine)”,Helv.Chim.Acta,2007,90,36-51.
11.F.AlbertCotton,HuiChao*,CarlosA.Murillo*andQingshengWang,“Atrimetalchaincocoonedbytwoheptadentatepolypyridylamideligands”,DaltonTrans.,2006,5416-5422.
12.FengGao,HuiChao*,FengZhou,Yi-XianYuan,BinPengandLiang-NianJi*,“DNAinteractionsofafunctionalizedruthenium(II)mixed-polypyridylcomplex[Ru(bpy)2ppd]2+”,J.Inorg.Biochem.,2006,100,1487-1494.
13.Yun-JunLiu,HuiChao*,Yi-XianYuan,Hui-JuanYuandLiang-NianJi*,“Ruthenium(II)mixed-ligandcomplexescontaining2-(6-methyl-3-chromonyl)imidazo-[4,5-f][1,10]phenanthroline:synthesis,DNA-bindingandphotocleavagestudies”,Inorg.Chim.Acta,2006,359,3807-3814.
14.HuiChao,Liang-NianJi,“Chapter11.Cobaltcomplexesaspotentialpharmaceuticalagents”,inMetallotherapeuticDrugsandMetal-BasedDiagnosticAgents:TheUseofMetalsinMedicine,Eds.MarcelGielenandEdwardR.T.Tiekink,May,2005,JohnWiley&SonsLtd(ISBN:0-470-86403-6).(BookChapter)
15.HuiChao*,Lian-NianJi,“DNAinteractionswithRu(II)polypyridinecomplexescontainingasymmetricligands”,BioinorganicChemistryandApplication,2005,3,15-28.(Review)
16.Yun-JunLiu,HuiChao*,Jun-HuaYao,Li-FengTan,Yi-XianYuan,Liang-NianJi,“Ruthenium(II)complexescontainingasymmetric2-(pyrazin-2-yl)naphthoimidazole:syntheses,characterization,DNA-bindingandphotocleavagestudies”,Inorg.Chim.Acta,2005,358,1904-1910.
17.Li-FengTan,HuiChao*,Yun-JunLiu,HongLi,BinSun,Liang-NianJi*,“DNA-bindingandphotocleavagestudiesof[Ru(phen)2(NMIP)]2+”,Inorg.Chim.Acta,2005,358,2191-2198.
18.Yun-JunLiu,HuiChao*,Li-FengTan,Yi-XianYuan,WeiWei,Liang-NianJi*.“Interactionofpolypyridylruthenium(II)complexcontainingasymmetricligandwithDNA”.J.Inorg.Biochem.,2005,99,530-537.
19.Li-FengTan,HuiChao*,HongLi,Yun-JunLiu,BinSun,WeiWei,Liang-NianJi*.“Synthesis,characterization,DNA-bindingandphotocleavagestudiesof[Ru(bpy)2(PPIP)]2+and[Ru(phen)2(PPIP)]2+”.J.Inorg.Biochem.,2005,99,513-520.
20.Yun-JunLiu,HuiChao*,Jun-HuaYao,HongLi,Yi-XianYuan,Liang-NianJi*.“Synthesis,characterizationandDNAinteractionstudiesof[Ru(bpy)2(CMIP)]2+and[Ru(phen)2(CMIP)]2+(CMIP=2-(3-chromonyl)imidazo[4,5-f][1,10]-phenanthroline)”.Helv.Chim.Acta,2004,87,3119-3130.
21.Xiang-LiWang,HuiChao*,HongLi,Xian-LanHong,Yun-JunLiu,Li-FengTan,Liang-NianJi*.“DNAinteractionsofcobalt(III)mixed-polypyridylcomplexescontainingasymmetricligands.”J.Inorg.Biochem.,2004,6,1143-1150.
22.Xiang-LiWang,HuiChao*,HongLi,Xian-LanHong,Liang-NianJi*,Xiao-YuanLi*.“Synthesis,crystalstructureandDNAcleavageactivitiesofcopper(II)complexeswithasymmetrictridentateligands.”,J.Inorg.Biochem.,2004,98,423-429.
23.Xian-LanHong,HuiChao*,Li-JunLin,Kang-ChengZheng*,HongLi,Xiang-LiWang,Feng-CunYun,Liang-NianJi*.“Synthesis,characterizationandDNA-bindingpropertiesofcomplexes[Ru(dppt)(dipn)]2+and[Ru(pta)(dipn)]2+.”Helv.Chim.Acta.,2004,87,1180-1193.
24.Xian-LanHong,HuiChao*,Jun-HuaYao,HongLi,Liang-NianJi*.“Synthesis,characterization,electrochemistryandsolvatochromicstudiesof[Ru(dppt)(dien)]2+and[Ru(pta)(dien)]2+”.Polyhedron,2004,23,815-821.
25.HuiChao*,Zhi-RenQiu,Li-RongCai,HaoZhang,Xiao-YuanLi*,Kam-SingWong,Liang-NianJi*.“Mono-,di-andtetranuclearruthenium(II)complexescontaining3-(pyridin-2-yl)-as-triazino[5,6-f]1,10-phenanthroline:synthesis,characterization,electrochemicalandphotophysicalproperties.”Inorg.Chem.,2003,42,8823-8830.
26.Cai-WuJiang,HuiChao*,HongLi,Liang-NianJi*,“Syntheses,CharacterizationandDNA-bindingStudiesofRuthenium(II)TerpyridineComplexes:[Ru(tpy)(PHBI)]2+and[Ru(tpy)(PHNI)]2+.”J.Inorg.Biochem.,2003,93,247-255.
27.Cai-WuJiang,HuiChao*,Xian-LanHong,HongLi,Wen-JieMei,Liang-NianJi*,“EnantiopreferentialDNA-
28.HuiChao*,Wen-JieMei,Qi-WenHuang,Liang-NianJi*,“DNABindingStudiesofRuthenium(II)ComplexesContainingAsymmetricTridentateLigands.”J.Inorg.Biochem.,2002,92,165-170.
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